Clinical trials: Pulpitis - Irreversible, open to volunteers
Symptomatic Irreversible Pulpitis (SIP)
Comparison Of Acetaminophen, NSAIDs, And Trypsin-Chymotrypsin Plus Acetaminophen For Post-Endodontic Pain After Single-Visit Root Canal Treatment
This randomized control trial will be planned according to PRIRATE 2020 guideline for reporting randomized trials in Endodontics.
- Trial name
- NCT07759349
- Testing
- Acetaminophen, NSAID, trypsin-chymotrypsin
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
the Effect of Instrumentation Kinematics on Intraoperative and Post-operative Pain
Effect of Instrumentation Kinematics on Intraoperative and Post-operative Pain in Maxillary Premolars With Acute Irreversible Pulpitis
Post-endodontic pain refers to the discomfort experienced following endodontic procedures. The incidence of post-operative pain is reported to be 25-40% regardless of the pulp and periradicular condition.
- Trial name
- Instrumentatio (NCT07250399)
- Testing
- EdgeOne Fire reciprocating system, JZ file system
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Al-Azhar University
Cryotherapy
Effect of Two Different Cryotherapy Irrigation Protocols on Postoperative Endodontic Pain
The aim of this study is to evaluate the effect of intracanal cryotreated (2-3°C) 2.5% sodium hypochlorite and Saline used throughout the procedure, compared with a room-temperature irrigation protocol with a final cryotreated…
- Trial name
- NAOCL/EDTA (NCT07676409)
- Testing
- Full Cryotherapy Irrigation (FC), Final Flush Cryotherapy Irrigation (FFC), Conventional Irrigation (CI)
- Volunteers
- 45 people
- Sponsor
- Cairo University
Irreversible Pulpitis (Toothache)
Evaluation Of Laser Versus Conventional Pulpotomies In Mature Molar Teeth With Irreversible Pulpitis
this clinical trial is evaluating the outcome of laser assisted pulpotomy compared to conventional pulpotomy in mature teeth with symptomatic irreversible pulpitis (SIP) assessed by CBCT followed by automated segmentation using…
- Trial name
- NCT07287709
- Testing
- Diode laser, Sodium Hypochlorite Solution
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Rana Hegaz
Symptomatic Irreversible Pulpitis, Symptomatic Apical Periodontitis
Effect of Cryotherapeutic and Nanotherapeutic Sodium Hypochlorite on Post-Operative Endodontic Pain.
This randomized clinical trial aims to compare the effects of conventional, cryotherapeutic, and nanotherapeutic sodium hypochlorite solutions used as final root canal irrigants on postoperative pain and substance P levels.
- Trial name
- NCT07923669
- Testing
- Cryotherapeutic Sodium Hypochlorite Irrigation., Nanotherapeutic Sodium Hypochlorite Irrigation
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- October 6 University
Irreversible Pulpitis
Child's Behavior Using Single Rotary File System Versus Manual Instrumentation in Pulpectomy of Primary Molars
The primary aim is to compare the behavior of the children during using conventional manual instrumentation versus rotary instrumentation by single rotary system for pulpectomy in primary molars through a Randomized Clinical…
- Trial name
- NCT07415694
- Testing
- Fanta AF F one rotary files 20 taper 4, Manual files (k files ,Mani, Inc., Japan).
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pulpectomy, Irreversible Pulpitis
Clinical and Radiographic Outcomes of Rotary Instrumentation in Primary Molars
This study will evaluate the clinical and radiographic outcomes of rotary versus manual pulpectomy in children with irreversible pulpitis.A single-visit pulpectomy will be performed for all patients.
- Trial name
- NCT07319741
- Testing
- Rotary Instrumentation, Manual Instrumentation
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Anfal mohamed elmotaz almogtaba
Irreversible Pulpitis, Apical Periodontitis
Bite Force Measurements
ABSTRACT: Acute dental pain from untreated decay often drives patients to emergency rooms (ERs), where the lack of definitive dental treatment results in nearly 75% of these patients receiving analgesics, predominantly opioids.
- Conditions
- Irreversible Pulpitis, Apical Periodontitis, Pulpal Necrosis
- Trial name
- NCT06843525
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- Rutgers, The State University of New Jersey
Symptomatic Irreversible Pulpitis and Post Operative Pain
Ultrasonic Activated Irrigation and Intracanal Cryotherapy for Reducing Pain After Root Canal Treatment
This randomized controlled trial aims to evaluate the effect of ultrasonic activated irrigation with and without intracanal cryotherapy on postoperative pain following single-visit root canal treatment in teeth with symptomatic…
- Trial name
- NCT07663227
- Testing
- Ultrasonic Activated Irrigation, Intracanal cryotherapy
- Volunteers
- 60 people
- Sponsor
- Dr Arsalan Ali Khan
Post Operative Pain
Assessment of Post-Operative Pain After Using Cryotherapy and Dexamethasone
Evaluation and comparing the effect of cryotherapy and dexamethasone on inflammatory mediators and post-operative pain in symptomatic irreversible pulpitis with acute apical periodontitis.
- Trial name
- NCT07738302
- Testing
- cold NaOCl , dexamethasone, NaOCl, dexamethasone, cold NaOCl and cold saline
- Volunteers
- 60 people
- Sponsor
- Suez Canal University
Symptomatic Irreversible Pulpitis (SIP)
Regenerative Potentials of Mature Mandibular Molars With Symptomatic Irreversible Pulpitis Enhanced With Different Scaffolds
The current study aims to assess the influence of different scaffolds on postoperative pain and success rate of pulpotomy in mandibular mature molars with symptomatic irreversible pulpitis
- Trial name
- NCT07196683
- Testing
- Regenerative pulpotomy
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Cairo University
Pulpitis - Irreversible
Outcome of Pulpotomy With MTA and Biodentin in Permanent Teeth With Caries Exposure
The success of pulpotomy treatment is affected by the type of biologically active material used.The effects of MTA and biodentine are compared in mature permanent teeth with caries exposure.It is expected that pulpotomy using…
- Trial name
- NCT06913283
- Testing
- Pulp Therapy with Mineral trioxide aggregate (MTA), Pulp Therapy with Biodentine
- Where
- Pakistan
- Volunteers
- 136 people
- Sponsor
- Altamash Institute of Dental Medicine
Pulpitis - Irreversible
Clinical and Radiographic Success of Pulpotomy Using Neoputty Mineral Trioxide Aggregate Versus Pulpectomy Using Endoflas In Primary Molars With Irreversible Pulpitis: A Randomized Controlled Trial
The goal of this randomized clinical trial is to evaluate the clinical and radiographic success of pulpotomy using Neoputty MTA vital primary molars diagnosed with symptomatic irreversible pulpitis.
- Trial name
- NCT06922578
- Testing
- NeoPUTTY MTA pulpotomy, Endoflas pulpectomy
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Cairo University
Symptomatic Irreversible Pulpitis and Post Operative Pain
Laser-Assisted vs Conventional Total Pulpotomy in Symptomatic Irreversible Pulpitis
his randomized controlled clinical trial will compare laser-assisted total pulpotomy with conventional total pulpotomy in permanent molar teeth diagnosed with symptomatic irreversible pulpitis.
- Trial name
- LASERPULP (NCT07850258)
- Testing
- Conventional Total Pulpotomy, Laser-Assisted Total Pulpotomy
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- meliksahgunduz
Post-operative Pain, Pulpitis - Irreversible
Outcomes of Pulpotomy and Root Canal Treatment in Teeth With Symptomatic Irreversible Pulpitis
The aim of this study is to evaluate the clinical effectiveness of total pulpotomy (TP), radicular pulpotomy (RP), and root canal treatment (RCT) in mandibular premolar and/or molar teeth diagnosed with symptomatic irreversible…
- Conditions
- Post-operative Pain, Pulpitis - Irreversible, Success Rate
- Trial name
- NCT07375576
- Testing
- Total Pulpotomy, Radicular pulpotomy, Root canal treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemal University
Root Canal Infection
Postoperative Pain After Using a Minimally Invasive Reciprocating Single-file System in Mandibular Molars With Symptomatic Irreversible Pulpitis
The aim of the present study is to assess the incidence and severity of postoperative pain after root canal preparation of mandibular molars with symptomatic irreversible pulpitis using a minimally invasive reciprocating…
- Trial name
- NCT07718607
- Testing
- Reciprocating rotary single-file system, Wave One Gold rotary file system
- Volunteers
- 56 people
- Sponsor
- Minia University
Symptomatic Irreversible Pulpitis
Preoperative Dexamethasone Injection to Improve Local Anesthesia Success in Endodontic Treatment
This study aims to determine whether giving a single dose of 4mg dexamethasone before root canal treatment can reduce the amount of pain patients experience during the procedure .
- Trial name
- DILAS (NCT07699315)
- Testing
- dexamethasone, Saline (0.9% NaCl)
- Volunteers
- 60 people
- Sponsor
- Watim Medical & Dental College
Pulpitis - Irreversible, Ozone
Zinc Oxide Ozonated Olive Oil in LSTR
This study will be carried out to evaluate and compare the clinical and radiographic effect of zinc oxide-ozonated olive oil (ZnO-OO) versus Modified Triple Antibiotic Paste (MTAP) as a Lesion Sterilization and Tissue Repair…
- Conditions
- Pulpitis - Irreversible, Ozone, Pulp Disease, Dental, Primary Teeth
- Trial name
- Zn-OO/MTAP (NCT06854744)
- Testing
- lesion sterlization and tissue repair, Zinc Oxide Ozonated Oil, Modified Triple Antibiotic Paste
- Where
- 2 sites in Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tanta University
Postoperative Pain
Effect of Passive Ultrasonic Irrigation Activation Cycle on Postoperative Pain
One of the most important goals of root canal treatment is to eliminate bacteria from infected canals. However, conventional irrigation methods combined with mechanical preparation applied during root canal treatment may not be…
- Trial name
- NCT06711029
- Testing
- Conventional needle irrigation, Passive Ultrasonic Irrigation with 3*20 sn, Passive Ultrasonic Irrigation with 6*10 sn
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Esin Özlek
Irreversible Pulpitis
Post Operative Pain Following Pulpectomy Versus Pulpotomy in Primary Molars Wit Irreversible Pulpitis
Study will evaluate and compare post operative pain for primary molars with irreversible pulpitis after pulpotomy and pulpuectomy
- Trial name
- NCT06903013
- Testing
- Non vitalPulp therapy, Vital pulp therapy
- Volunteers
- 50 people
- Sponsor
- Minia University