Clinical trials: Puncture
Post-Dural Puncture Headache
Effectiveness of Nebulized Dexmedetomidine for Treatment of Obstetric Post-Dural Puncture Headache
Postdural puncture headache (PDPH) is a common complication, following neuraxial techniques. The obstetric population is particularly prone to PDPH. Therefore, treatment of PDPH is a key issue in obstetric anesthesia.
- Trial name
- NCT04327726
- Testing
- Dexmedetomidine Nebulization, 0.9% Saline Nebulization
- Where
- Egypt
- Volunteers
- 43 people
- Sponsor
- Zagazig University
Central Nervous System Infections, Pseudotumor Cerebri
A Study to Test Performance of Needle Placements for Neuraxial Procedures Using Tactile Imaging vs Control
This study will compare the VerTouch device to the conventional palpation technique for performing diagnostic and therapeutic neuraxial procedures.
- Conditions
- Central Nervous System Infections, Pseudotumor Cerebri, Neurological Disorder, Cancer
- Trial name
- NCT04796935
- Testing
- Tactile Imaging (VerTouch), Control (palpation)
- Where
- 3 sites in United States
- Volunteers
- 95 people
- Sponsor
- IntuiTap Medical, Inc
Pain, Patient Satisfaction
Patient-Controlled Sedation in Port Implantation (PACSPI-2)
The goal of the study is to determine if patient-controlled sedation (PCS) with propofol and alfentanil reduces patient-reported pain perception during implantation of subcutaneous venous port (SVP).
- Conditions
- Pain, Patient Satisfaction, Cancer, Venous Puncture
- Trial name
- PACSPI-2 (NCT05688384)
- Testing
- Propofol + Alfentanil
- Where
- Sweden
- Volunteers
- 340 people
- Sponsor
- Region Jönköping County
Post-Lumbar Puncture Headache
Headache After Diagnostic Lumbar Puncture
The objectives of this study are to investigate the effects of needle design, needle size and stylet reinsertion on the risk for headache after diagnostic LP (lumbar puncture, Post-LP headache).
- Trial name
- HELPUmeå (NCT03960749)
- Testing
- Sprotte 25G needle, stylet reinserted, Sprotte 25G needle, stylet not reinserted, Sprotte 22G needle, stylet reinserted
- Volunteers
- 1,000 people
- Sponsor
- Jonatan Salzer
Conscious Sedation, Simple Lacerations Less Than 4 cm
A Comparison of Intranasal Midazolam and Nitrous Oxide (N2O) Minimal Sedation for Minor Procedures in a Pediatric Emergency Department
The objective of this project is to compare the sedative effects of intranasal midazolam versus inhaled nitrous oxide (N2O) for minor procedures in the pediatric emergency department.
- Conditions
- Conscious Sedation, Simple Lacerations Less Than 4 cm, Lumbar Punctures, Minor Incision Drainage of Abscesses Not Requiring Extensive Debridement
- Trial name
- NCT03085563
- Testing
- Nitrous Oxide, Midazolam
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- University of Colorado, Denver
Pudendal Nerve Block
Ultrasound-guided Pudendal Nerve Block in Children: A Descriptive Study of Feasibility
Objective: Description of a new transperineal technique of pudendal nerve block (PNB), under ultrasound-guidance. Methods : Successive inclusions after parental consent of 60 children undergoing perineal surgery under general…
- Trial name
- NCT02496325
- Testing
- Ultrasound guided transperineal pudendal nerve block
- Where
- France
- Volunteers
- 196 people
- Sponsor
- University Hospital, Montpellier
Post Dural Puncture Headache
Effect of Intravenous Oxytocin on Post Dural Puncture Headache After Caesarean Sections
Spinal anesthesia is the preferred anesthetic technique for cesarean section because of its advantages over epidural and general anesthesia.
- Trial name
- NCT07853924
- Testing
- oxytocin, Normal Saline
- Volunteers
- 100 people
- Sponsor
- Assiut University
Cardiovascular Diseases, Bleeding
Safe and Fast Radial Hemostasis Using Synergistic Strategies: SAFE & FAST Trial
The Safe and Fast Radial Hemostasis using Synergistic Strategies (SAFE \& FAST) trial is an interventional study aimed at reducing the incidence of radial artery occlusion (RAO) rebound bleeding, and the required compression…
- Conditions
- Cardiovascular Diseases, Bleeding, Arterial Puncture, Catheter Complications
- Trial name
- NCT06549842
- Testing
- Heparin, Terumo Radial Band, Vaosband
- Where
- 2 sites in United States, India
- Volunteers
- 451 people
- Sponsor
- Regional Hospital of Scranton
Spinal Puncture Complications
Optimization Lumbar Puncture In Children
The study is carried out in a prospective randomized controlled way. In the context of informed understanding from parents, compared with traditional process(no anesthesia; lying without the pillow and fasting water and food for…
- Trial name
- OLPIC (NCT02454894)
- Testing
- lidocaine, postoperative management
- Sponsor
- Beijing Children's Hospital
Spinal Cord Injuries, Myofascial Pain Syndrome
Effectiveness of Dry Needling as a Treatment of Shoulder Myofascial Pain Syndrome in Spinal Cord Injury Patients
Shoulder pain in people with spinal cord injury is one of the most prevalent in acute and chronic patients because of weakness in shoulder periarticular muscles, and also because of overuse of these part of the body in assistive…
- Conditions
- Spinal Cord Injuries, Myofascial Pain Syndrome, Shoulder Pain, Puncture
- Trial name
- NCT03709797
- Testing
- Dry needling in infraspinatus muscle
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad de León
Atrial Fibrillation
Conventional Versus RF Needle Transseptal Puncture for Cryoballoon Ablation
This will be a prospective single-blinded, randomized, controlled trial comparing the effectiveness and safety of transseptal puncture using the Baylis transseptal system to transseptal left atrial access with standard…
- Trial name
- CRYO-LATS (NCT03199703)
- Testing
- Baylis transseptal system group, Standard conventional transseptal group
- Where
- 6 sites in Canada
- Volunteers
- 135 people
- Sponsor
- Jason Andrade
Parturients in Labour
Alteration in Hearing Following Accidental Dural Puncture. A Study in Parturients
Headache following accidental dural punction as during epidural analgesia can be severe and sometimes very disabling. The incidence of PDPH is 10-40%, most starting within 48 h of dural puncture.
- Trial name
- AHEAD (NCT01682967)
- Where
- 2 sites in Sweden
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Örebro University, Sweden
Chronic Low Back Pain (CLBP)
Disc Puncture Does Not Accelerate Degenerative Changes in Lumbar Discs of Patients With Discogenic Pain
Procedures 10 years ago performed included intradiscal nucleoplasty (ACUTHERM) and intradiscal electrothermal therapy (IDET). At follow up MRI scans evaluated by two blinded specialists for disc degeneration were carried out.
- Trial name
- NCT07567404
- Testing
- Intradiscal electrothermal Therapy
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- SRH Gesundheitszentrum Bad Herrenalb
Validation, Dried Blood Spot
To Validate an Analytical Method to Measure Concentration of Tacrolimus in Blood Taken From Finger Pricks
The principal aim of this study is to define the relationship between tacrolimus concentrations determined from the finger prick DBS (Dry Blood Spot) method and those determined from blood samples collected by venepuncture in…
- Conditions
- Validation, Dried Blood Spot, Transplant Patients
- Trial name
- NCT02377609
- Testing
- Tacrolimus
- Where
- 6 sites in France, United Kingdom
- Volunteers
- 108 people
- Sponsor
- Astellas Pharma Europe Ltd.
Intracranial Hypotension
The Blood Patch in the Management of Intracranial Hypotension
Intracranial hypotension results from leakage and/or hypotension of cerebrospinal fluid. It can be spontaneous or secondary to a dural puncture complicating perimedullary anesthesia or a lumbar puncture.
- Trial name
- BPIH (NCT06498804)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Strasbourg, France
Acute Myocardial Infarction
SpinChip Hs-cTnI Sample Type Validation
During a heart attack, the protein troponin I is released from the heart muscle into the bloodstream. Measurements of cardiac troponin in blood are used as an aid in the diagnosis of heart attack.
- Trial name
- HEAT-2 (NCT06453707)
- Testing
- SpinChip hs-cTnI
- Where
- Norway
- Volunteers
- 180 people
- Sponsor
- SpinChip Diagnostics ASA
Nurse's Role, Simulation
Training Procedural Simulation of Nurses in Reducing Complications Related to Arteriovenous Fistula Puncture
Interest of training in procedural simulation of nurses in the reduction of complications related to arteriovenous fistula puncture in hemodialysis patients
- Conditions
- Nurse's Role, Simulation, Arteriovenous Fistula
- Trial name
- SIMFAV (NCT03680209)
- Testing
- Simulation
- Where
- France
- Volunteers
- 1,280 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Pain Management, Hemodialysis
Virtual Reality Distraction During Arteriovenous Fistula Puncture
The cannulation of arteriovenous fistula is a painful procedure in hemodialysis patients. Previous studies have shown the effectiveness of virtual reality in reducing pain during needle-related procedures
- Conditions
- Pain Management, Hemodialysis, Virtual Reality
- Trial name
- NCT05399199
- Testing
- virtual reality distraction
- Where
- Egypt
- Volunteers
- 93 people
- Sponsor
- Mansoura University
Calcific Tendinitis of the Shoulder
Comparison of the Effect of Radial Shock Wave, Ultrasound-guided Needle Puncture, and Combination of Both in the Treatment of Calcific Tendinitis of the Shoulder
Calcific tendinitis of the shoulder is a common enthesopathy, and is characterized by inflammation around calcium hydroxyapatite crystal deposits, usually located in the supraspinatus tendon, near its insertion place.1 The…
- Trial name
- NCT02677103
- Testing
- radial extracorporeal shock wave therapy, ultrasound-guided needle puncture, RSWT and USNP
- Where
- Taiwan
- Volunteers
- 61 people
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Mechanical Complication of Cardiac Pacemaker
Comparison of Axillary Vein Puncture With Subclavian Vein Puncture in Pacemaker Implantation
The intrathoracic subclavian venous technique for pacemaker implantation may be associated with serious complications. Axillary vein puncture tends to reduce lead implantation complications such as pneumothorax and lead crush…
- Trial name
- NCT02358551
- Testing
- Placement of electrode lead through axillary vein puncture, Placement of electrode lead through subclavian vein puncture
- Where
- China
- Volunteers
- 220 people
- Sponsor
- China-Japan Friendship Hospital