Clinical trials: Puncture
Labor Pain, Epidural Analgesia
Different Spinal Needles Sizes and Dural Puncture Epidural For Labor Analgesia
The rationale behind the dural puncture epidural (DPE) technique lies in the fact that a dural perforation with a spinal needle purportedly creates a conduit for accelerated translocation of local anesthetics from the epidural to…
- Trial name
- NCT03389945
- Testing
- 25G Dural Puncture Epidural Block, 27G Dural Puncture Epidural Block
- Where
- 2 sites in Chile
- Volunteers
- 140 people
- Sponsor
- University of Chile
ALLERGIC RHINITIS
Repeated Nasal Challenge in Skin Prick-puncture Negative and Intradermal Positive Dust Mite Allergic Rhinitis Patients
Subjects who have a clinical history of perennial rhinitis symptoms associated with dust exposure or not associated with other perennial allergens, will have a positive challenge with Dermatophagoides pteronyssinus.
- Trial name
- DUSTMITE (NCT01179282)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Tecar Therapy Efficacy in the Treatment of PDPH
Radiofrequency Therapy of the Neck Muscles for Treating the Post-dural Puncture Headache After Cesarean Delivery.
Postdural puncture headache (PDPH) is a frequent complication after neuraxial anaesthesia due to accidental puncture of the dura mater. After spinal anaesthesia, the rate of PDPH may reach up to 28,7% of cases.
- Trial name
- NCT05695677
- Testing
- Capacitive-Resistive Radiofrequency therapy of the neck muscles
- Where
- 2 sites in Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Pruritus
Inter-arm and Inter-period Reproducability of the Dermal Blood Flow Response After a Histamine Skin Prick.
To evaluate the inter-arm and inter-period reproducibility of the dermal blood flow response induced by a skin prick of histamine, subjects will receive histamine (10 mg/ml) and negative control skin pricks on the volar surface…
- Trial name
- NCT04396977
- Testing
- Histamine 10 mg/ml skin prick
- Where
- Belgium
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Post-Dural Puncture Headache
Effect of Small Versus Large Epidural Needles on Postdural Puncture Headache Study
The purpose of this study is to determine the effect of 19g versus =>18g traditional Tuohy-type epidural needles on the incidence and severity of postdural puncture headache (PDPH).
- Trial name
- NCT00370604
- Testing
- 19g Tuohy-type epidural needle, 23g catheter, => 18g Tuohy-type needle
- Where
- 4 sites in Canada
- Volunteers
- 1,081 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Nesting Technique During Heel Prick Blood Collection, Natural Position During Heel Prick Blood Collection
Nestıng Technıque for Paın Management Durıng Heel Prick in Term Neonates
Background: Determining the effectiveness of pain management strategies in newborns provide evidence to promote high-quality midwifery practices.
- Trial name
- Nestıng (NCT07462884)
- Testing
- Nesting technique
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Mersin University
Radial Artery Spasm
Topical Nitroglycerine for Prevention of Radial Artery Spasm
In a randomized, double-blind trial, 100 patients undergoing angiography were pre-treated with either topical nitroglycerin (NTG) or placebo.
- Trial name
- NCT06912139
- Testing
- Nitroglycerin transdermal
- Where
- Romania
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy "Victor Babes" Timisoara
Allergy, Anxiety
The Effects of Virtual Reality and Music on Pain, Anxiety, Itching, and Vital Signs
Aim: This study aimed to examine the effects of virtual reality and music on pain, anxiety, itching, and vital signs of children during a skin prick test and evaluation.
- Conditions
- Allergy, Anxiety, Pain, Itching
- Trial name
- NCT06479967
- Testing
- The VR glasses group, the music group
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Uludag University
Anesthesia, Spinal Puncture
Intravenous Fentanyl or Local Anesthetic Infiltration for Pain Reducing During Spinal Needle Insertion
Background and Objectives: Spinal puncture is painful procedure which may cause patient refusal of spinal anesthesia in future surgery.
- Trial name
- NCT01157247
- Testing
- Comparison of intravenous fentanyl and local anesthetic infiltration in pain reducing during spinal needle puncture
- Where
- Croatia
- Volunteers
- 88 people
- Sponsor
- Croatian Society of Regional Anesthesia and Analgesia
Interventional Radiology
The Impact of Puncture Angle on Total Fluoroscopy Time Reduction During Percutaneous Biliary Drainage
The purpose of this study is to retrospectively assess the importance of initial bile duct puncture angle on total fluoroscopy time and overall efficacy during ultrasound and fluoroscopy guided percutaneous transhepatic biliary…
- Trial name
- NCT04653987
- Testing
- Percutaneous biliary drainage
- Volunteers
- 130 people
- Sponsor
- Institut za Rehabilitaciju Sokobanjska Beograd
Hymenoptera Allergy
Determinism of the Mechanism of Action of Specific Immunotherapy in Hymenoptera Venom Allergy
Currently, most of the protocols used for desensitization to Hymenoptera venoms consist of a very rapid increase in doses of venom extracts administered during the SIT in a day without systemic reaction of the patient which is…
- Trial name
- MAISAVEN (NCT02295488)
- Testing
- biological sampling, Desensitization protocol (Alyostall®)
- Where
- France
- Volunteers
- 29 people
- Sponsor
- University Hospital, Rouen
Depression, Anxiety
The Effect of Psychological State on Post Spinal Puncture Headache and Backache
To investigate the effect of patient mood before spinal anesthesia on post spinal puncture headache and backache
- Trial name
- NCT03427372
- Testing
- anxiety scale, depression scale
- Where
- Turkey (Türkiye)
- Volunteers
- 370 people
- Sponsor
- Ahi Evran University Education and Research Hospital
Allergy Skin, Allergic Skin Reaction
SPT for Sensitization of Collagen Dressing
The goal of this clinical trial is to determine the sensitization (contact allergy) potential of the test product ColActive Plus Collagen Matrix Dressing after a skin prick test on the skin of healthy human subjects.
- Trial name
- NCT06271993
- Testing
- ColActivePlus Collagen Matrix Dressing
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Covalon Technologies Inc.
Cardiovascular Diseases, Acute Abdomen
Effectiveness of Point of Care Blood Analysis Obtained From Skin Puncture Blood
This study aimed to evaluate the correlation between the point of care blood analysis obtained from skin puncture blood and conventional blood analysis obtained from venous and arterial blood.
- Conditions
- Cardiovascular Diseases, Acute Abdomen, Respiratory Disease, Renal Disease
- Trial name
- NCT03096665
- Testing
- blood test
- Where
- South Korea
- Volunteers
- 250 people
- Sponsor
- Hanyang University
Pain, Anxiety
Midazolam Sedation for Neonatal Lumbar Puncture
Lumbar puncture is one of the most common painful procedures performed on neonates in the Emergency Department (ED). The investigators will study in a randomized controlled trial, the efficacy of intravenous administration of a…
- Trial name
- NCT00942539
- Testing
- Midazolam
- Where
- Israel
- Volunteers
- 12 people
- Sponsor
- Rambam Health Care Campus
Atrial Fibrillation, Left Atrial Appendage Closure
The Usefulness of Biatrial 3D Printing to Plan Transseptal Puncture for the Left Atrial Appendage Closure
The aim of the study is to assess the usefulness of pre-procedural 3D printing of both atria to plan optimum site for transseptal puncture for the left atrial appendage closure.
- Trial name
- NCT05743322
- Testing
- Left atrial appendage closure
- Where
- Czechia
- Volunteers
- 60 people
- Sponsor
- Charles University, Czech Republic
Pain
The Effects of the Parents' Voice to Reduce the Heel Puncture Pain in High-Risk Neonates
High-risk neonates are forced to be separated from their parents due to hospitalization, and clinical medical treatment often causes pain and physical stress in high-risk newborns.
- Trial name
- NCT05003661
- Testing
- Parents' Voice
- Where
- Taiwan
- Volunteers
- 105 people
- Sponsor
- National Yang Ming Chiao Tung University
Pain
Video/Audio Distraction Analgesia for Simulated Oncology Procedure Pain
The purpose of this study is to compare the analgesic efficacy of three different types of video/audio distraction in normal volunteers subjected to carefully controlled and non-injurious thermal pain delivered to the skin of the…
- Trial name
- NCT00701571
- Testing
- Virtual Reality distraction
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Washington
Vascular Closure, Endovascular Procedure
Safety and Efficacy of the Vascular Closure Device (Tonbridge) in Hemostasis Treatment of Femoral Artery Puncture
The purpose of this study is to verify the safety and efficacy of the Vascular Closure Device (Tonbridge) in hemostasis treatment for femoral artery puncture.
- Conditions
- Vascular Closure, Endovascular Procedure, Hemostasis, Femoral Artery
- Trial name
- NCT05822804
- Testing
- Vascular Closure Device (Tonbridge), EXOSEAL Vascular Closure Device (Codis Corporation)
- Where
- 7 sites in China
- Volunteers
- 228 people
- Sponsor
- Ton-Bridge Medical Tech. Co., Ltd
Post-Dural Puncture Headache, Ganglion Sphenopalatine Block
The Effect of Ganglion Sphenopalatine Block (GSP-block) Follow-Up
The purpose of this study is to evaluate the long term effects of the ganglion sphenopalatine block (GSP block) on postdural puncture headache.
- Trial name
- GSP-FOLLOW (NCT05301387)
- Testing
- Ganglion Sphenopalatine Block
- Where
- Denmark
- Volunteers
- 38 people
- Sponsor
- University Hospital Bispebjerg and Frederiksberg