Clinical trials: Puncture
Pain, Anxiety
Lumbar Puncture in Emergency Under Nitrous OXide
Lumbar puncture (LP) is a frequent exam that can cause pain and anxiety. In a scheduled setting, it has been shown that nitrous oxide use during the procedure was able to reduce both pain and anxiety.
- Trial name
- LENOX (NCT03941990)
- Testing
- Fixed 50:50 mixture of nitrous oxide and oxygen
- Where
- France
- Volunteers
- 88 people
- Sponsor
- University Hospital, Clermont-Ferrand
Surgery Scheduled
Evaluating the Effectiveness of Dermal Analgesia Provided by the Application of Lidocaine and Prilocaine Cream 5% on the Puncture Site of Axillary Blocks
Prospective Study, monocentric, controlled, randomized study. Evaluating the effectiveness of dermal analgesia provided by the application of Lidocaine and Prilocaine Cream 5% on the puncture site of axillary blocks.Our study…
- Trial name
- NCT01673542
- Testing
- Lidocaine-Prilocaine 5%, DEXERYL
- Where
- France
- Volunteers
- 32 people
- Sponsor
- Poitiers University Hospital
Aortic Dissection, Left Subclavian Artery Occlusion
Endovascular Repair With In Situ nEedle feNestration of Left Subclavian Artery to Treat AoRtic Dissection(RISEN STAR):A Multicenter Prospective Trial.
Background: Aortic dissection (AD) is a common emergency in vascular surgery, which seriously threatens human life and health. The rupture of Stanford type B dissection is located in aortic arch and the dissection range is from…
- Conditions
- Aortic Dissection, Left Subclavian Artery Occlusion, Vascular Diseases, Interventional Therapy
- Trial name
- NCT05186181
- Testing
- In situ fenestration
- Where
- China
- Volunteers
- 217 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Post-Dural Puncture Headache
Is Aminophylline More Effective Than Neostigmine/Atropine Mixture in the Treatment of Post-dural Puncture Headache
Objectives: To compare the safety and efficacy of IV aminophylline versus IV neostigmine/atropine mixture in the treatment of post-dural puncture headache (PDPH).
- Trial name
- RCT (NCT03997006)
- Testing
- IV Aminophylline, IV Neostigmine Methylsulfate + Atropine Sulphate
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Damanhour Teaching Hospital
Postdural Puncture Headache, Sphenopalatine Ganglion Block
Sphenopalatine Ganglion Block for Post-Dural Puncture Headache
The investigators are attempting to determine a less invasive method of treatment for postdural puncture headaches that can occur after regional anesthesia.
- Trial name
- NCT02181205
- Testing
- bupivacaine
- Where
- United States
- Sponsor
- Wake Forest University Health Sciences
Coronary Catheterization
Comparing Advanced Hemostasis and Ultrasound-Guided Puncture to Conventional Approaches in Distal Radial Access
Meta-analysis results show that distal radial access (DRA) is associated with a significant reduction in the risk of radial artery occlusion compared to conventional transradial access (TRA).
- Trial name
- ALPHA&OMEGA (NCT06835829)
- Testing
- Transradial potassium ferrate hemostatic patch, Distal radial potassium ferrate hemostatic patch, Ultrasound-guidance
- Where
- 6 sites in Belgium, Italy
- Volunteers
- 480 people
- Sponsor
- Associazione per lo Studio delle Malattie Cardiovascolari Cardiva ONLUS
Postdural Puncture Headache
The Relationship Between Post Dural Puncture Headache and Joint Laxity
Post-spinal headache is divided into 3 according to the severity scale. It is divided into 3 groups as mild, moderate and severe according to the presence of symptoms such as nausea, vomiting, and dizziness that prevent daily…
- Trial name
- NCT05212194
- Testing
- examination
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Adiyaman University Research Hospital
Hypersensitivity, Food
Prospective Study About Sensitization Pattern to Insects as Food Source in Patients With House Dust Mite Allergy
Patients allergic to seafood and/or sensitized to Tropomyosin of Skin Prick tests SPT or crustacean origin will may be also be sensitized to edible insects.
- Trial name
- InFood (NCT04239131)
- Testing
- Skin prick test
- Where
- Switzerland
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Pain
"Lidocaine 4% Cream (LMX4) vs Placebo for Pain Due to Lumbar Puncture in Infants 0-60 Days of Age."
The study's hypothesis is LMX4 cream, a topical anesthetic cream, will reduce the pain of infants undergoing Lumbar Puncture (spinal tap).
- Trial name
- NCT00533468
- Testing
- Lidocaine Cream 4%
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- State University of New York at Buffalo
Lumbar Puncture
AI-Assisted Instruction Versus Peer Learning for Sustained Lumbar Puncture Competency
This study compared three teaching methods for training resident physicians in lumbar puncture, a critical medical procedure used to collect spinal fluid for diagnosing conditions like meningitis.
- Trial name
- AI-Assisted (NCT07873073)
- Testing
- Peer Learning
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Diminished Ovarian Reserve (DOR)
Multi-Site Cortical Puncture for DOR
A multicenter, prospective, randomized controlled clinical trial. The target population consists of patients undergoing IVF/ICSI artificial reproduction who plan to undergo ovarian stimulation and embryo retrieval (DOR) within 4…
- Trial name
- MSCPD (NCT07568639)
- Testing
- multiple ovarian cortex punctures, routine oocyte retrieval procedure
- Where
- 7 sites in China
- Volunteers
- 214 people
- Sponsor
- First Affiliated Hospital of Guangxi Medical University
Radial Artery Hemostasis
Radial Artery Puncture Hemostasis Study
RAPHE is an open label randomized clinical trial to assess physical, biological and chemical methods of radial artery puncture hemostasis following coronary catheterization.
- Trial name
- RAPHE (NCT04857385)
- Testing
- Radial artery hemostasis
- Where
- 3 sites in Hungary
- Volunteers
- 600 people
- Sponsor
- Semmelweis University Heart and Vascular Center
Dural Puncture Epidural Technique
The Impact of Using Different Spinal Needle Sizes on the Efficacy of the Dural Puncture Epidural Block
The aim of this study is to compare the dural puncture epidural technique (DPET) with either 25-gauge spinal needle or 27-gauge spinal needle versus conventional epidural technique and evaluate whether DPET improves onset and…
- Trial name
- NCT06287047
- Testing
- Epidural analgesia
- Where
- Egypt
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cardiovascular Diseases, Acute Abdomen
Effectiveness of Point of Care Blood Analysis Obtained From Skin Puncture Blood
This study aimed to evaluate the correlation between the point of care blood analysis obtained from skin puncture blood and conventional blood analysis obtained from venous and arterial blood.
- Conditions
- Cardiovascular Diseases, Acute Abdomen, Respiratory Disease, Renal Disease
- Trial name
- NCT03096665
- Testing
- blood test
- Where
- South Korea
- Volunteers
- 250 people
- Sponsor
- Hanyang University
Chronic Obstructive Pulmonary Disease
Efficacy of Interval Aerobic Training Versus Laser Puncture Therapy on Restless Leg Syndrome in Copd Patient
DETERMINE HOW TO IMPROVE THE QUALITY OF LIFE FOR PATIENTS WITH COPD BY DECREASING TINTENSITY OF THE RESTLESS SYNDROME
- Trial name
- NCT06955000
- Testing
- traidmail, laser puncture therapy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Pharos University in Alexandria
Cesarean Section, Postoperative Nausea and Vomiting (PONV)
Restrictive vs Liberal Intraoperative Fluid Strategy and Postoperative Outcomes After Elective Cesarean Section
Spinal anesthesia for elective cesarean section is frequently associated with hemodynamic instability and postoperative complications such as postoperative nausea and vomiting (PONV) and delayed gastrointestinal recovery.
- Conditions
- Cesarean Section, Postoperative Nausea and Vomiting (PONV), Postdural Puncture Headache (PDPH), Postoperative Ileus
- Trial name
- NCT07440667
- Testing
- Restrictive intraoperative crystalloid fluid strategy (≤3 mL/kg/h), Liberal intraoperative crystalloid fluid strategy (>3 mL/kg/h)
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Nigde Omer Halisdemir University
Dural Puncture Epidural Technique
Dural Puncture Epidural Technique Versus Conventional Epidural Technique During Vaginal Surgeries
The study aims to evaluate whether the dural puncture epidural technique (group B) improves sacral block anesthesia during vaginal surgeries compared with the conventional epidural technique (group A).
- Trial name
- NCT04921761
- Testing
- Conventional epidural, Dural puncture epidural
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Research Centre, Egypt
Analgesia, Obstetrical, Post-Dural Puncture Headache
Intrathecal Catheter Placement Versus Resiting Epidural Catheter After Dural Puncture in Obstetric Patients
Epidural anesthesia represents the most popular method for pain relief during labour. Unintentional dural puncture (UDP) occurs in 0.4-1.5% of labour epidural analgesia, representing therefore the most common complication.
- Trial name
- ItaREVI (NCT05977361)
- Testing
- Resiting Epidural Catheter, Intrathecal Catheter Placement
- Volunteers
- 181 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Food Allergy
Skin Prick Test for the Diagnosis of Food Allergy- a Comparison of Different Commercial Extracts and Raw Food
Immediate food allergy is , sometimes , a life threatening situation . Diagnosis is done by skin prick test with commercial extracts.
- Trial name
- NCT01508299
- Testing
- skin test
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Meir Medical Center
Chronic Low Back Pain (CLBP)
Disc Puncture Does Not Accelerate Degenerative Changes in Lumbar Discs of Patients With Discogenic Pain
Procedures 10 years ago performed included intradiscal nucleoplasty (ACUTHERM) and intradiscal electrothermal therapy (IDET). At follow up MRI scans evaluated by two blinded specialists for disc degeneration were carried out.
- Trial name
- NCT07567404
- Testing
- Intradiscal electrothermal Therapy
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- SRH Gesundheitszentrum Bad Herrenalb