Clinical trials: Puncture
Pruritus
Influence of Antipruritics on the Dermal Blood Flow Response to Histamine, Cinnamaldehyde and Capsaicin.
In order to validate the accuracy and reliability of the histamine skin prick model for histaminergic itch and vasodilation, the dermal blood flow response induced by a histamine skin prick will be evaluated after the…
- Trial name
- NCT04399148
- Testing
- Desloratadine 5 mg, Aprepitant 125 mg, Ketotifen 1 MG
- Where
- Belgium
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Pediatric Lumbar Puncture
Identification of Cerebrospinal Fluid With Injeq IQ-Needle During Paediatric Lumbar Puncture
This is clinical feasibility study on the device performance with paediatric patients. The main objective is to validate the performance of investigational device in distinguishing and identifying the cerebrospinal fluid (CSF)…
- Trial name
- NCT02792660
- Testing
- Injeq IQ-Needle
- Where
- 2 sites in Finland
- Volunteers
- 40 people
- Sponsor
- Injeq Ltd
Newborn, Maternal Voice
The Effect of Maternal Voice and Music Therapy on Pain and Stress During Heel Prick Testing in Newborns
During the adaptation process to the extrauterine environment, healthy newborns face procedures such as hepatitis B vaccination, vitamin K injection, blood sugar monitoring, bilirubin or metabolic disease screening.
- Conditions
- Newborn, Maternal Voice, Music Therapy, Heel Prick Testing
- Trial name
- NCT07773792
- Testing
- Music Therapy, Maternal Voice
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Bilecik Seyh Edebali Universitesi
Deep Intracerebral Hemorrhage (ICH)
Neuronavigation-assisted Stereotactic Puncture With Tenecteplase for Acute Intracerebral Hemorrhage
Background Minimally invasive puncture surgery followed by thrombolysis has been proven to be an effective approach for managing hypertensive intracerebral hemorrhage.
- Trial name
- NAS-TNK (NCT06868511)
- Testing
- Neuronavigation-assisted Stereotactic Minimally Invasive Puncture Combined with Tenecteplase, Standard medical treatment
- Where
- China
- Volunteers
- 732 people
- Sponsor
- Beijing Tiantan Hospital
Blood Flow Indexes
Doppler Ultrasonography Assessed Vascular Changes Before and After Radial Artery Puncture
The investigators designed a study to assess whether there were any blood flow indexes change before and after radial artery puncture with doppler ultrasonography
- Trial name
- NCT03294993
- Testing
- Ultrasound assess
- Where
- China
- Sponsor
- China Medical University, China
Chronic Kidney Diseases
The Effect of Virtual Reality Application on Pain Due to Fistula Puncture in Hemodialysis Patients
The aim of this study is to examine the effect of virtual reality application on fistula puncture-related pain (FPi-A) in hemodialysis patients.
- Trial name
- NCT05807906
- Testing
- virtual reality application
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people
- Sponsor
- Hacettepe University
Respiratory Tract Disease, Acute Pain
Intranasal Ketamine as a Sedative for Venipuncture
Randomized clinical trial, controlled, double-blind, parallel two-arm.
- Conditions
- Respiratory Tract Disease, Acute Pain, Diseases of the Digestive System
- Trial name
- NCT02929524
- Testing
- Ketamine
- Volunteers
- 39 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Procedural Pain in Newborns
Leg and Foot Massage for Pain in Newborns Receiving Heel Stick
This study aims to evaluate the effect of a leg and foot massage program on pain in newborns receiving heel stick for monitoring serum bilirubin levels.
- Trial name
- NCT07893028
- Testing
- Leg and Foot Massage
- Where
- Thailand
- Volunteers
- 42 people
- Sponsor
- Chulalongkorn University
Hemodialysis Patients
Effect on Pain and Comfort Associated With Fistula Puncture
Purpose This study was carried out as the design of the targeted design in terms of targeting and comfort in the patient with hemodialysis.
- Trial name
- NCT05574595
- Testing
- Music theraphy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kırklareli University
Laparoscopic Entry Technique
A Comparison of Three Different Entry Points to Establish the Pneumoperitoneum
The Palmer's point and periumbilical region are the common laparoscopic entry site to establish the pneumoperitoneum. In the present study, the investigators assess the safety and feasibility of Meng's point as a new laparoscopic…
- Trial name
- NCT02804529
- Testing
- Veress needle
- Where
- China
- Volunteers
- 90 people
- Sponsor
- China-Japan Friendship Hospital
Kidney Transplant Failure and Rejection
Home Based Monitoring of Kidney Transplants Utilizing Capillary Microsamples
Renal transplant recipients are followed as out patients at the transplant center for about 8 weeks after surgery. Between 1-2 weeks after surgery, 50 standard immunological patients will be randomized (1:1) to either follow…
- Trial name
- HBM-KTx (NCT04369612)
- Testing
- Standard follow-up, Home-based monitoring
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- Oslo University Hospital
Post-Dural Puncture Headache
Is Theophylline More Effective Than Sumatriptan in the Treatment of Post-dural Puncture Headache
Objectives: To compare the safety and efficacy of oral theophylline versus oral sumatriptan in the treatment of post-dural puncture headache (PDPH).
- Trial name
- NCT04257851
- Testing
- Theophylline Anhydrous Oral Tablet, Sumatriptan Succinate Oral Tablet
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Damanhour Teaching Hospital
Immediate Hypersensitivity
Comparison of Difference Histamine Concentration (1, 5 and 10 mg/ml) for Skin Prick Test Positive Control
Skin prick test (SPT) was used for diagnostic test for type 1 hypersensitivity. The efficacy and safety of SPT were proved. The positive control of SPT is histamine.
- Trial name
- NCT02561429
- Testing
- SPT
- Where
- Thailand
- Volunteers
- 180 people
- Sponsor
- Mahidol University
Anesthesia, Spinal Puncture
Intravenous Fentanyl or Local Anesthetic Infiltration for Pain Reducing During Spinal Needle Insertion
Background and Objectives: Spinal puncture is painful procedure which may cause patient refusal of spinal anesthesia in future surgery.
- Trial name
- NCT01157247
- Testing
- Comparison of intravenous fentanyl and local anesthetic infiltration in pain reducing during spinal needle puncture
- Where
- Croatia
- Volunteers
- 88 people
- Sponsor
- Croatian Society of Regional Anesthesia and Analgesia
Acute Lymphoblastic Leukemia, Pediatric
Virtual Reality During Lumbar Punctures in Acute Lymphoblastic Leukemia
Over 90% of children and adolescents diagnosed with acute lymphoblastic leukemia (ALL) will survive long term. Part of the successful treatment that patients receive is the delivery of chemotherapy directly into their spinal…
- Trial name
- VIRALL (NCT06722638)
- Testing
- Use of Virtual Reality Headset
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Children's National Research Institute
Anesthesia, Local, Headache
Ultrasonographic Optic Nerve Sheath Diameter in Postdural Puncture Headache Diagnosis
This study aims to investigate the hypothesis that ultrasonographic optic nerve sheath diameter (ONSD) measurement can help predict the development and severity of postdural puncture headache (PDPH) in patients undergoing spinal…
- Trial name
- NCT07100158
- Testing
- Ultrasonographic Measurement of Optic Nerve Sheath Diameter (ONSD)
- Where
- Turkey (Türkiye)
- Volunteers
- 176 people
- Sponsor
- Ankara City Hospital Bilkent
Puncture Site Pain
Vapocoolant Spray Effectiveness On Arterial Puncture Pain: Randomized Double Blind Placebo-Controlled Trial
This study was aimed to compare pain levels from arterial blood gas (ABG) sampling performed with vapocoolant spray in comparison to placebo.
- Trial name
- NCT01860248
- Testing
- Vapocoolant spray, Water spray
- Where
- Iran
- Volunteers
- 80 people
- Sponsor
- Tehran University of Medical Sciences
Local Anesthetics, Ultrasound Guidance
Duplex Guided Application of Local Anesthetic Before Femoral Artery Catheterization
The aim of this study is to evaluate the optimization of local anesthetic effect with duplex ultrasound-guided injection of lidocaine before femoral artery puncture during diagnostic or therapeutic interventional procedures.
- Conditions
- Local Anesthetics, Ultrasound Guidance, Catheterization
- Trial name
- NCT00903825
- Testing
- Ultrasound guided injection of femoral local anesthetic (lidocaine), Injection of femoral local anesthetic (lidocaine) with manual palpation
- Where
- Greece
- Volunteers
- 200 people
- Sponsor
- University of Patras
Headache
Treatment of Post-dural Puncture Headache in Postpartum Patients: Sphenopalatine Ganglion Block to Epidural Blood Patch.
The purpose of this research study is to compare the effectiveness of a sphenopalatine ganglion block to an epidural blood patch for post-dural puncture headache relief in randomized postpartum parturients over a 48 hour period.
- Trial name
- NCT02962427
- Testing
- Sphenopalatine ganglion Block, Epidural blood patch
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Colorado, Denver
Lumbar Puncture
Ultrasound Guided Diagnostic Lumbar Puncture in Neurology
Subjects who are having a lumbar puncture as part of their clinical care will be randomized to either a traditional landmark based lumbar puncture or ultrasound guided lumbar puncture.
- Trial name
- NCT03815045
- Testing
- Landmark-based lumbar puncture, Ultrasound-guided lumbar puncture
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Dartmouth-Hitchcock Medical Center