Clinical trials: Puncture
Post-Dural Puncture Headache
Sphenopalatine Block Versus Greater Occipital Nerve Block in PDPH
Management of postdural puncture headache (PDPH) has always been challenging for anesthesiologists. PDPH not only increases the misery of the patient, but the length of stay and overall cost of treatment in the hospital also…
- Trial name
- NCT05235256
- Testing
- bilateral sphenopalatine ganglion block, bilateral greater occipital nerve block, lidocaine plus dexamethasone
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Headache Disorders, Secondary, Post-Dural Puncture Headache
Association Between Chronic Headache and Back Pain With Childbirth
This study uses a single questionnaire to evaluate two separate primary outcomes: 1. To identify association between chronic headache in women who have given birth to children as compared to a control group of women who have…
- Conditions
- Headache Disorders, Secondary, Post-Dural Puncture Headache, Migraine Disorders, Back Pain
- Trial name
- NCT04091321
- Where
- United States
- Volunteers
- 1,112 people
- Sponsor
- Stanford University
Osteoporotic Vertebral Compression Fractures, Vertebroplasty
Standardized Study Protocol of Percutaneous Vertebroplasty Based on Pedicle Nine-Grid Zoning Method
The goal of this clinical trial is to verify the safety and efficacy of the pedicle "Nine-grid Zoning Method" in assisting percutaneous vertebroplasty (PVP) for the treatment of lumbar osteoporotic vertebral compression fractures…
- Trial name
- NCT07616583
- Testing
- Nine-grid Area Division Method Assisted PVP, Traditional Standard Percutaneous Vertebroplasty (PVP)
- Where
- China
- Volunteers
- 68 people
- Sponsor
- Beijing Friendship Hospital
Drug Use, Hepatitis C
Evaluation of the Use of the GenXpert to Detect Hepatitis C RNA
The results of the GX device are equivalent to standard venous blood sampling. With this study we are going to determine the prevalence in drug users with difficult venous access.
- Trial name
- NCT04717856
- Testing
- screening: HCV RNA test and risk factors questionaire
- Where
- Belgium
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Spontaneous Intracranial Hypotension, Intracranial Hypotension
Pathophysiology and Treatment of Cerebrospinal Hypotension Exploration Study
The goal of this observational study is to learn about the effects of a low-pressure environment on the brain in patients with intracranial hypotension and to potentially improve diagnostics and treatment of this condition.
- Conditions
- Spontaneous Intracranial Hypotension, Intracranial Hypotension, Post-Lumbar Puncture Headache
- Trial name
- PATCHES (NCT06805591)
- Where
- Denmark
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Lumbar Puncture
The First Puncture Success Rate of a Novel Injeq IQ-Tip™ System in Pediatric Lumbar Punctures
The investigation aims to demonstrate the first puncture success rate, as proxy of clinical benefit and clinical performance, of bioimpedance spectroscopy based spinal needle guidance method among pediatric hemato-oncology…
- Trial name
- IQ-LP-03 (NCT04070144)
- Testing
- IQ-Tip(tm) system
- Where
- 3 sites in Finland
- Volunteers
- 50 people
- Sponsor
- Injeq Ltd
Hemostasis of Arterial Punctures
Safety and Efficacy Study Comparing Thrombin for Arterial Sealing
This trial is designed as a prospective, multi-center, randomized, double blinded clinical trial to evaluate the safety and efficacy of the Thrombin VSI.
- Trial name
- NCT00388284
- Testing
- Arterial Sealing
- Where
- 6 sites in United States
- Volunteers
- 270 people
- Sponsor
- Vascular Solutions LLC
Post-Dural Puncture Headache
Evaluation of Post-dural Puncture Headache in Female Patients Undergoing Obstetric and Non-obstetric Surgery
The goal of this observational study is to compare the incidence, severity, and potential risk factors for Post-dural Puncture headaches (PDPH) in obstetric and non-obstetric female patients undergoing spinal anesthesia.
- Trial name
- NCT06992063
- Testing
- Spinal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Duzce University
Intratumoral Injection, Cancer
The Clinical Efficacy and Safety of Intratumoral Injection of Chemotherapy for Advanced Solid Tumors
This project intends to investigate the clinical efficacy of intra-tumoural injection of chemotherapeutic agents (e.g. cisplatin, oxaliplatin, etc.)via fine needle aspiration guided by CT or ultrasound in patients with advanced…
- Trial name
- NCT06430515
- Testing
- Intratumoral Injection of Chemotherapy
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Wuxi People's Hospital
Dry Eyes, Sjogren's Disease With Dry Eyes
Treating Dry Eyes and Corneal Ulcers With Fingerprick Autologous Blood
To investigate if fresh finger prick autologous blood (FAB) instead of serum from venesection, is a safe and effective treatment for dry eyes and corneal ulcers/ epithelial defects.
- Conditions
- Dry Eyes, Sjogren's Disease With Dry Eyes, Persistent Corneal Epithelial Defects, Chronic Corneal Ulcers
- Trial name
- FAB (NCT02153515)
- Testing
- Your own ( autologous) finger prick of blood produced with a diabetic lancet
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Bedford Hospital NHS Trust
Biomarker
Exploring the Potential of Finger Prick Blood for Assessment of BIOmarkers for LOw Grade Inflammation and CVD Risk
There are currently no minimally invasive techniques for the measurement of lipopolysaccharide (LPS) and Apo-B48 that can be used in samples collected in field settings.
- Trial name
- BIOLOGIC (NCT04996589)
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- Wageningen University and Research
Pain
Contribution of Hypnosis During a Lumbar Puncture.
The purpose of this study is to assess the effect of hypnosis, as add on therapy, on patients requiring a lumbar puncture (LP) as part of their medical management.
- Trial name
- HYPNOPLUS (NCT05092906)
- Testing
- LP with complementary hypnoanalgesia, LP with standard of care
- Where
- France
- Volunteers
- 74 people
- Sponsor
- University Hospital, Grenoble
Vascular Access Complication, Coronary Artery Disease
Distal Radial Access for Coronary Procedures
Distal radial access (DRA) in the anatomical snuffbox (AS) is a relatively novel approach that can be considered an alternative to trans radial access (TRA) for coronary procedures.
- Conditions
- Vascular Access Complication, Coronary Artery Disease, STEMI, Non STEMI
- Trial name
- DISTAL (NCT06165406)
- Testing
- Distal radial access
- Where
- Spain
- Volunteers
- 2,000 people
- Sponsor
- Hospital Arnau de Vilanova
Pain
Laser Acupuncture for Pain Prevention in Neonates
Pain prevention and/or therapy in neonates is still a challenge. It is widely accepted that early pain experience can have a tremendous impact on the pain memory.
- Trial name
- NCT00528125
- Testing
- active laser acupuncture
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Children Hospital Homburg
Acute Lymphoblastic Leukemia, Pediatric
Virtual Reality During Lumbar Punctures in Acute Lymphoblastic Leukemia
Over 90% of children and adolescents diagnosed with acute lymphoblastic leukemia (ALL) will survive long term. Part of the successful treatment that patients receive is the delivery of chemotherapy directly into their spinal…
- Trial name
- VIRALL (NCT06722638)
- Testing
- Use of Virtual Reality Headset
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Children's National Research Institute
Gynecologic Disease Requiring Laparoscopic Hysterectomy Under Neuraxial Anesthesia
Dural Puncture Epidural Technique Versus Conventional Epidural Techmique
This study will be conducted on 50 patients of ASA grade I and II aged from 25 to 55 years and presented for laparoscopic hysterectomy.
- Trial name
- NCT05032677
- Testing
- Conventional Epidural Technique, Dural Puncture Epidural Technique using pencil-point 25G Whitacre needle
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Coronary Artery Disease, Puncture
Hemostasis Pad Using Chitosan After Invasive Percutaneous Procedures
Arterial access is the key step during the endovascular treatment of cardiovascular diseases. This study was designed to confirm the safety and efficacy of the hemostasis pad using chitosan in patients undergoing percutaneous…
- Trial name
- NCT02954029
- Testing
- ezClot (hemostasis pad), BloodSTOP ix pad, Rotary compression device
- Where
- South Korea
- Volunteers
- 315 people
- Sponsor
- Seoul National University Bundang Hospital
Healthy
Central Venous Catheter Insertion Train the Trainer
The investigators previously successfully implemented a central venous catheter (CVC) simulation-based mastery learning (SBML) curriculum at Northwestern University.
- Trial name
- NCT02402257
- Testing
- CVC Train the Trainer
- Where
- United States
- Volunteers
- 226 people
- Sponsor
- Northwestern University
Pregnancy Related, Analgesia, Epidural
Dural Puncture Epidural vs Standard Epidural Analgesia in Labor
This randomized prospective study compares Dural Puncture Epidural (DPE) and Standard Epidural Analgesia in term laboring women.
- Conditions
- Pregnancy Related, Analgesia, Epidural, Labor Pain
- Trial name
- DPE-LABOR (NCT07278895)
- Testing
- Dural Puncture Epidural (DPE), Standard Epidural Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Allergy, Nut
Low Dose Multi-Nut Oral Immunotherapy in Pre-schoolers With a Multi-Nut Allergy
The LMNOP trial will be a 2-armed, open-label, randomised controlled trial (RCT), 2:1. Over a period of 18 months, children in the Multi-Nut Oral Immunotherapy Treatment (OIT) Group (experimental arm) will undergo low dose OIT to…
- Trial name
- LMNOP (NCT05049512)
- Testing
- Multi-nut OIT
- Where
- Australia
- Volunteers
- 12 people
- Sponsor
- Murdoch Childrens Research Institute