Clinical trials: Puncture
Post-Dural Puncture Headache
Effect of Intrathecal Neostigmine on Post-dural Puncture Headache.
Intravenous neostigmine was recently reported as an effective treatment for PDPH for parturients after intrathecal (IT) block which is postulated to be through its central effects on CSF secretion and cerebral vascular tone…
- Trial name
- NCT05289323
- Testing
- Neostigmine Methylsulfate, Dextrose 5%/Nacl 0.9% Inj
- Where
- Egypt
- Volunteers
- 722 people
- Sponsor
- Alexandria University
Pain Score (VAS)
Nebulized Dexmedetomidine or Lidocaine for Treatment of Post Dural Puncture Headache in Parturients Undergoing Elective Cesarean Section Under Spinal Anesthesia
Post-dural puncture headache (PDPH) is a well-recognized and potentially serious complication of subarachnoid block. While advancements in spinal needle design have reduced its incidence in recent years, PDPH still affects a…
- Trial name
- NCT06607861
- Testing
- saline group, dexmedetomidine group, lidocaine group
- Where
- Egypt
- Volunteers
- 114 people
- Sponsor
- Minia University
Premature Infant, Breast Feeding, Exclusive
Amphia Premature Infant Pain Study
Last thirty years, many research was performed concerning pain in the newborn. These investigations showed us the negative effects of pain in the neonatal period.
- Conditions
- Premature Infant, Breast Feeding, Exclusive, Puncture Skin
- Trial name
- APIP (NCT01276366)
- Testing
- breast feeding, supplemental breast milk, sucrose
- Where
- Netherlands
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Amphia Hospital
Labor Pain
Dural Puncture Epidural (DPE) Technique: Efficacy and Safety Overview.
Neuraxial techniques such as lumbar epidural and combined spinal-epidural (CSE) are the most effective methods for labor analgesia and are associated with high patient satisfaction.
- Trial name
- NCT07704554
- Testing
- Dural Puncture Epidural (DPE) Technique
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Ohio State University
Blood Gas Analysis, Pain
A Randomized Controlled Trial on the Effect of Needle Gauge on the Pain and Anxiety Experienced During Arterial Puncture
Arterial blood-gas (ABG) measurements are the gold standard to evaluate pulmonary gas exchange. However, arterial punctures are more painful than venous punctures and, in ICU patients, cause greater anxiety than tracheal…
- Trial name
- NCT02320916
- Testing
- 23Gauge, 25Gauge
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Rouen
Pain, Patient Satisfaction
Patient-Controlled Sedation in Port Implantation (PACSPI-2)
The goal of the study is to determine if patient-controlled sedation (PCS) with propofol and alfentanil reduces patient-reported pain perception during implantation of subcutaneous venous port (SVP).
- Conditions
- Pain, Patient Satisfaction, Cancer, Venous Puncture
- Trial name
- PACSPI-2 (NCT05688384)
- Testing
- Propofol + Alfentanil
- Where
- Sweden
- Volunteers
- 340 people
- Sponsor
- Region Jönköping County
Hunter Syndrome
Collection and Study of Cerebrospinal Fluid in Patients With Hunter Syndrome
The purpose of the study is to collect data on CSF biomarkers in patients with Hunter Syndrome that would serve as reference data for comparison with cognitively impaired patients with Hunter syndrome, patients with other…
- Trial name
- NCT01449240
- Testing
- No treatment
- Where
- 7 sites in United States, United Kingdom
- Volunteers
- 10 people
- Sponsor
- Shire
Lumbar Puncture
Ultrasound-assisted vs Palpation-guided Lumbar Punctures
The goal of this randomized clinical trial is to determine whether ultrasound-assisted lumbar puncture improves first-needle insertion success compared with the standard palpation technique in adults undergoing a clinically…
- Trial name
- NCT07824284
- Testing
- Ultrasound-Assisted Lumbar Puncture, Standard Palpation-Guided Lumbar Puncture
- Where
- 2 sites in United States
- Volunteers
- 132 people
- Sponsor
- The Cooper Health System
Pruritus
Influence of H1-antihistamines on the Dermal Blood Flow Response to Histamine, Cinnamaldehyde and Capsaicin.
In order to validate the accuracy and reliability of the histamine skin prick model for histaminergic itch and vasodilation, the dermal blood flow response induced by a histamine skin prick will be evaluated after the…
- Trial name
- NCT04399525
- Testing
- Desloratadine Single Dose, Levocetirizine Single Dose, Desloratadine Fourfold Dose
- Where
- Belgium
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Rotator Cuff Tendinitis, Ultrasonography, Interventional
Ultrasound-guided Lavage of Calcific Deposits of the Rotator Cuff
The primary goal of the study is to assess ultrasonographic Power Doppler signals after ultrasound-guided puncture and lavage of rotator cuff calcific tendinitis of the shoulder.
- Conditions
- Rotator Cuff Tendinitis, Ultrasonography, Interventional, Ultrasonography, Doppler, Color
- Trial name
- Kalklavage (NCT05264935)
- Testing
- Ultrasound-Guided Puncture and Lavage (UGPL)
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Schulthess Klinik
Heart Diseases, Atrial Septal Dilatation
Transcatheter Microguidewire Drilling for Transseptal Left Atrial Access
This study aims to investigate the safety and efficacy of transcatheter microguidewire drilling (TMD) for transseptal left atrial access in patients with abnormal atrial septal morphology.
- Trial name
- TMD (NCT04561908)
- Testing
- Transseptal puncture with Brockenbrough-needle, Microguidewire-assisted transseptal puncture
- Where
- 2 sites in China
- Volunteers
- 100 people
- Sponsor
- China National Center for Cardiovascular Diseases
Pain, Acute, Venous Puncture
Procedural Pain in Children: Intervention With the Hospital Clown
This study evaluates the effect of an intervention with a hospital clown compared to standard care on pain experience for acute hospitalized children receiving venipuncture.
- Conditions
- Pain, Acute, Venous Puncture, Children, Adult
- Trial name
- NCT03366623
- Testing
- Hospital clown, No hospital clown intervention
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
HIV Infections
HIV - Monotherapy in Switzerland (MOST-ch)
The investigators plan to conduct a two arm study, to compare failure rates in the central nervous system (CNS) and genital compartment in virologically fully suppressed patients continuing a highly active antiretroviral therapy…
- Trial name
- MOST (NCT00531986)
- Testing
- Lopinavir-Monotherapy, HAART
- Where
- 6 sites in Switzerland
- Volunteers
- 60 people
- Sponsor
- Cantonal Hospital of St. Gallen
Postdural Puncture Headache
Sphenopalatine Ganglion Block for Postdural Puncture Headache
Background: Postdural puncture headache (PDPH), which is one of the complications of spinal anesthesia, is a condition that negatively affects the quality of life of patients, causes late mobilization and prolonged hospital stay.
- Trial name
- NCT04892290
- Testing
- Conservative Treatment for Postdural Puncture Headache
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Sakarya University
Arterio-venous Fistula, Puncture, Chronic Desease
Impact of the Arteriovenous Fistula Puncture Technique On the Hemodialysis Session For Patient and Caregiver
40000 patients are hemodialysis each year in France . In the case of chronic care, 78% of patients have an arteriovenous fistula.
- Trial name
- NCT03355508
- Testing
- pucture in the arteriovenous fistula
- Where
- France
- Volunteers
- 42 people
- Sponsor
- Poissy-Saint Germain Hospital
Asthma
A Study of Efficacy of New Doses of Xolair to Protect From Allergen Challenge in Groups of Asthma Patients Defined by IgE Levels
This study was intended to demonstrate that patients with standard and high immunoglobulin E (IgE) levels can be protected from allergen induced broncho-constriction by Xolair
- Trial name
- NCT00624832
- Testing
- Xolair
- Where
- 6 sites in Germany, Netherlands and 1 more
- Volunteers
- 60 people
- Sponsor
- Novartis
NPH (Normal Pressure Hydrocephalus)
The Effects of Exercise on Gait Characteristics, Balance, and Performance in Patients With Normal Pressure Hydrocephalus
The goal of this study is to investigate effect of exercise program on balance, gait and performance in patients with normal pressure hydrocephalus applied with lumbar puncture.
- Trial name
- NCT05679934
- Testing
- Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people
- Sponsor
- Dokuz Eylul University
Lumbar Puncture
Ultrasound Assisted Lumbar Puncture in the Neonate
Clinicians are often unable to successfully do a spinal tap. Ultrasound has been proposed as a method to improve success but it is not known if it helps. This study is designed to see if ultrasound improves the success rate.
- Trial name
- NCT02918149
- Testing
- Palpation Landmark Technique, Ultrasound-Assisted Technique LP
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- Children's Hospital of Philadelphia
Anxiety and Fear
The Effect of Therapeutic Play on Children's Anxiety and Fear Before Lumbar Puncture
The study will be conducted with the randomized controlled experimental method. The children who attended the pediatric department will divide into two groups via randomization in the computer environment.
- Trial name
- NCT06199206
- Testing
- Theraputic Play
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Maltepe University
Newborn
Pain and Comfort Levels During Heel Stick Blood Sampling in Newborns
Aim: The study was designed to determine the effect of Buzzy® and Shotbloker® application on pain and comfort levels in newborns during heel pricking. Method:The study was a randomised controlled trial.
- Trial name
- NCT07081048
- Testing
- Buzzy®.Group, ShotBlocker Group
- Where
- Turkey (Türkiye)
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Tarsus University