Clinical trials: Puncture
Nervous System Diseases
Cerebrospinal Fluid Collection and Repository Storage
Background: Cerebrospinal fluid (CSF) is the liquid around the brain and spinal cord. Many diseases can only be diagnosed by examining the CSF. A lumbar puncture is used to collect and test CSF.
- Trial name
- NCT01862107
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Lumbar Puncture, Pediatrics
Video-Assisted Informed Consent for Neonatal Lumbar Puncture
The purpose of this study is to explore the effectiveness of video-assisted neonatal lumbar puncture consent processes against a conventional consent discussion to inform parents about pediatric lumbar puncture in the pediatric…
- Conditions
- Lumbar Puncture, Pediatrics, Emergency Department Patient, Informed Consent
- Trial name
- NCT07074925
- Testing
- Video assisted informed consent, Standard consent
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Texas at Austin
Traumatic Lumbar Puncture
Variability of Infant LP Insertion Site Based On Procedural Experience
The reported rate of unsuccessful traditional LP in children (defined as the inability to obtain cerebrospinal fluid or obtaining a traumatic puncture) is as high as 50%.
- Trial name
- NCT02949869
- Testing
- Spinal Sonography
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Lumbar Puncture, Virtual Reality
Effect of Virtual Reality Distraction on Pain, Anxiety, Vital Signs in Patients Undergoing Lumbar Puncture
Lumbar puncture (LP) is one of the most frequently applied interventional procedures in the clinical field. It is still used as the gold standard diagnostic tool in some infectious and non-infectious diseases.
- Conditions
- Lumbar Puncture, Virtual Reality, Distraction
- Trial name
- NCT07044856
- Testing
- distraction with virtual reality
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Inonu University
Calcific Tendinitis of the Shoulder
Comparison of the Effect of Radial Shock Wave, Ultrasound-guided Needle Puncture, and Combination of Both in the Treatment of Calcific Tendinitis of the Shoulder
Calcific tendinitis of the shoulder is a common enthesopathy, and is characterized by inflammation around calcium hydroxyapatite crystal deposits, usually located in the supraspinatus tendon, near its insertion place.1 The…
- Trial name
- NCT02677103
- Testing
- radial extracorporeal shock wave therapy, ultrasound-guided needle puncture, RSWT and USNP
- Where
- Taiwan
- Volunteers
- 61 people
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Lung Cancer
Study on the Diagnosis of Ground-glass Lung Cancer by Microwave Ablation Combined With Puncture Biopsy
This study is a multicenter study. It plans to screen 200 patients with pulmonary nodule lesions with ground glass as the main body, take CT thin-layer scanning 3D reconstruction, apply AI and fragment omics technology to…
- Trial name
- NCT06776588
- Testing
- Microwave ablation combined with biopsy
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Beidahuang Industry Group General Hospital
Fever
Ultrasound-Assisted Lumbar Puncture in Children
The aim of this study is to determine if emergency physician performed ultrasound-assisted lumbar puncture improves first-time success rates in a pediatric population.
- Trial name
- NCT03099642
- Testing
- ultrasound-assisted lumbar puncture
- Where
- Canada
- Volunteers
- 166 people
- Sponsor
- St. Justine's Hospital
Kidney Transplantation, Liver Transplantation
A Study to Compare the Finger Prick Whole Blood MITRA Assay Method With the Established Venepuncture Whole Blood Method for Quantitative Determination of Tacrolimus Blood Concentrations in Transplant Patients
The purpose of this study is to assess relationship between tacrolimus concentrations determined via whole blood MITRA assay method with those determined using the established and validated whole blood venepuncture method using…
- Trial name
- MITRA (NCT03465969)
- Testing
- tacrolimus
- Where
- 4 sites in France, United Kingdom
- Volunteers
- 80 people
- Sponsor
- Astellas Pharma Europe Ltd.
Virtual Reality, Children, Only
Use of Virtual Reality Mask During Blood and Skin Allergic Tests in 7 to 13 Children
Main objective : Evaluate the effect of using a virtual reality mask during the blood test and pricks tests in allergic children aged from 7 to 13 years.
- Conditions
- Virtual Reality, Children, Only, Pain, Procedural, Anxiety and Fear
- Trial name
- REVAPRICK (NCT05378581)
- Testing
- Virtual reality mask, control arm
- Where
- 2 sites in France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Clermont-Ferrand
Pulmonary Nodules
Robot-Assisted Versus Manual Puncture for Pulmonary Nodule Ablation
Pulmonary nodule ablation is an established minimally invasive treatment for selected patients with pulmonary nodules. Accurate puncture is critical for procedural efficiency and safety.
- Trial name
- NCT07714629
- Where
- China
- Volunteers
- 104 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Procedural Pain, Procedural Anxiety
Three Distraction Techniques for Pain and Anxiety in Children During Allergy Skin Prick Testing
This randomized controlled trial compared three distraction techniques-animated cartoons, DistrACTION® Cards, and interactive video games-with standard care for reducing procedural pain and anxiety in children aged 6-10 years…
- Trial name
- NCT07796087
- Testing
- Animated cartoon distraction, Distraction card intervention, Interactive video game distraction
- Where
- Turkey (Türkiye)
- Volunteers
- 161 people
- Sponsor
- Istanbul University
Lumbar Puncture
Hemorrhage Elimination During Lumbar Puncture Using Ultrasound Measurements (HELPUS)
This is a clinical trial to determine the extent to which ultrasound-assisted lumbar puncture using a standardized procedure, including use of ultrasound to ascertain the presence of cerebrospinal fluid (CSF) at L3 - L5 and the…
- Trial name
- HELP (NCT07612644)
- Testing
- ultrasound contrast
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Vanderbilt University Medical Center
Interventional Radiology
The Impact of Puncture Angle on Total Fluoroscopy Time Reduction During Percutaneous Biliary Drainage
The purpose of this study is to retrospectively assess the importance of initial bile duct puncture angle on total fluoroscopy time and overall efficacy during ultrasound and fluoroscopy guided percutaneous transhepatic biliary…
- Trial name
- NCT04653987
- Testing
- Percutaneous biliary drainage
- Volunteers
- 130 people
- Sponsor
- Institut za Rehabilitaciju Sokobanjska Beograd
Anesthetic Regional Techniques for Vaginal Surgeries
Regional Anesthesia
Both techniques are efficacious for sacral anesthesia during vaginal surgeries. Dural puncture epidural technique allows partial confirmation of epidural catheter placement.
- Trial name
- NCT04933500
- Testing
- Whitacre spinal needle
- Where
- Egypt
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Reham Ali Abdelhaleem Abdelrahman
Ultrasound Therapy; Complications
Utility of Ultrasound-Guided Site Marking in Pediatric Lumbar Punctures
The standard way to identify landmarks in the spine before inserting a needle for a lumbar puncture is to feel by touch. The purpose of this research is to determine if doing an ultrasound to identify landmarks before performing…
- Trial name
- NCT04828746
- Testing
- Ultrasound Guided Skin Marking
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Carilion Clinic
Submucosal Tumor, Pancreas Tumor
25G and 22G Puncture Needles
The screened patients were randomly assigned 25G puncture needles and 22G puncture needles in a 1;1 ratio, based on the computer-generated random order, before receiving an ultrasound endoscope puncture.
- Trial name
- NCT05101772
- Where
- China
- Volunteers
- 73 people
- Sponsor
- Peking Union Medical College Hospital
Cryptococcal Meningitis, HIV
Study Evaluating Efficiency and Tolerance of High-dose Fluconazole Associated With Flucytosine as Induction Therapy for Cryptococcal Meningitis Associated With HIV in Sub-saharan Africa
The aim of the trial is to demonstrate that in a sub-Saharan African setting, the association of: 1. Oral treatment : high dose of fluconazole (1600mg/d) associated with flucytosine (100 mg/kg/j) as induction therapy 2.
- Trial name
- Flucocrypto (NCT01715922)
- Testing
- Fluconazole, Flucytosine, lumbar punctures
- Where
- 7 sites in Burundi, Côte d’Ivoire
- Volunteers
- 41 people
- Sponsor
- ANRS, Emerging Infectious Diseases
Traumatic Tap
Lumbar Puncture Stylet Technique in Children
Lumbar puncture (LP) is a procedure performed frequently among children in the emergency department (ED). Although it has been performed for decades, and for distinct indications, the technique itself can often lead to traumatic…
- Trial name
- LiPSTICk (NCT05009173)
- Testing
- Lumbar puncture using the stylet-in technique, Lumbar puncture using the stylet-out technique
- Where
- Canada
- Volunteers
- 395 people
- Sponsor
- St. Justine's Hospital
Allergic Rhinitis, Allergic Asthma
Diagnostic Equivalence of the Skin Prick Test Tape vs. Conventional Skin PrickTest
Testing of a new ready-to-use Tape in comparison to the currently used skin prick test for the diagnosis of allergies. Assessment of clinical equivalence of the SPT Tape for representative common inhalant allergens to…
- Conditions
- Allergic Rhinitis, Allergic Asthma, Allergic Conjunctivitis, Food Allergy
- Trial name
- SPTTapeD1 (NCT03820154)
- Testing
- Skin Prick Test, Skin Prick Test TAPE
- Volunteers
- 75 people
- Sponsor
- Prof. Dr. Claus Bachert BVBA
Hemostasis of Arterial Punctures
Flow Dynamics During Simulated Hemostasis at the Proximal and Distal Radial Arteries
Transradial access (TRA) has been widely adopted for coronary angiography and percutaneous coronary intervention, as it has been shown to significantly reduce bleeding complications, vascular complications, and mortality compared…
- Trial name
- FLOW-PRADA (NCT07686003)
- Testing
- Air-filled hemostatic band
- Where
- South Korea
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Wonju Severance Christian Hospital