Clinical trials: Puncture
Cryotherapy Effect
Evaluation of Efficacy of Cryotherapy for Skin Anesthesia During Arterial Puncture
the purpose of this study is to evaluate the cryotherapy effect by vapocoolant spray to reducing pain during puncture for artérial blood gas
- Trial name
- SNOW (NCT03973385)
- Testing
- Cryotherapy
- Where
- 4 sites in France
- Volunteers
- 200 people
- Sponsor
- Versailles Hospital
Two Different Techniques to Perform Epidural Using Ultrasound
Accuro and the Use of Real Time Ultra Sound With Acoustic Puncture Assisted Device to Confirm Epidural Space End Point
Aim of the work: To compare the use of the Accuro ultrasound and a real time ultrasound guided epidural combined with the acoustic puncture assisted device to perform the epidural anesthesia Secondary aim is to compare the…
- Trial name
- NCT04204070
- Testing
- Accuro, APAD
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Newborn Pain
The Effect of 3 Different Auditory Applications on Newborn Heel Prick Procedure
In pain management of neonates in interventional applications, health professionals should be able to evaluate pain, reduce or eliminate pain. Pharmacologic and nonpharmacologic methods are used in pain management.
- Trial name
- NCT06167551
- Testing
- mother lullaby group, white noise group, classical music group
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Namik Kemal University
Spinal Puncture, Diagnostic Imaging
Ultrasound-Assisted Lumbar Puncture
Although the lumbar puncture is a common procedure and has been performed without ultrasound for decades, other research studies suggest that there may be some benefits to using ultrasound.
- Trial name
- NCT03167190
- Testing
- Point-of-care ultrasound, Traditional Landmark-based Lumbar Puncture
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Asthma, Perennial Allergic Rhinitis
Subcutaneous Immunotherapy for Mouse in Adults
This is an open label trial of mouse allergenic extract administered by subcutaneous injection in adults with asthma and mouse sensitivity.
- Trial name
- SCITMO (NCT02532179)
- Testing
- Mouse Allergenic Extract
- Where
- 4 sites in United States
- Volunteers
- 12 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Acute Pain
Effect of Remote Local Peripheral Nerve Cooling on Pain of Arterial Puncture
In this project, volunteers will be recruited to cool the superficial skin of the axillary brachial plexus away from the puncture point, resulting in local peripheral nerve cooling, and observe its impact on the pain of arterial…
- Trial name
- NCT06838572
- Testing
- Skin cooling to 20°C, Skin cooling to 15°C, Skin cooling to 8°C
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Postdural Puncture Headache
Cosyntropin Versus Epidural Blood Patch (EBP) for Treatment of Treatment of Post Dural Puncture Headache
PDPH is a common problem after either intentional or unintentional Dural puncture. It is especially common in young female patients and in patients undergoing Lumbar Puncture using the typical kit containing large 20 gauge…
- Trial name
- PDPH (NCT02394457)
- Testing
- Cosyntropin, Epidural Blood Patch
- Volunteers
- 29 people
- Sponsor
- United States Naval Medical Center, San Diego
Pacemaker, Implantable Cardioverter-defibrillator
Ultrasound-guided Axillary Versus Conventional Cephalic Venous Access for Implantation of Cardiac Devices
The implantation of cardiac electronic devices is a common procedure in the Electrophysiology Laboratory. The most commonly used venous access sites are the cephalic, the axillary and the subclavian vein.
- Trial name
- NCT04958369
- Testing
- Ultrasound-guided axillary venous access, Cephalic venous access
- Where
- Greece
- Volunteers
- 114 people
- Sponsor
- University Hospital of Patras
Allergy to House Dust, Allergy Pollen
Validation and Reproducibility of S.P.A.T. With Allergens
To improve accuracy and take out human error opportunities, Hippo Dx developed S.P.A.T., an automated skin prick test. This study will provide a comparison between manual and automated skin prick test in allergic and non-allergic…
- Trial name
- NCT05824637
- Testing
- Skin Prick Automated Test, Skin Prick Manual Test
- Where
- Belgium
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Hippocreates
Theophylline, Sumatriptan
Theophylline, Versus Sumatriptan and Gabapentin in The Treatment of Post-Dural Puncture Headache
The aim of this study is to compare the safety and efficacy of theophylline, sumatriptan, and gabapentin in the treatment of post-dural puncture headache.
- Conditions
- Theophylline, Sumatriptan, Gabapentin, Post-Dural Puncture Headache
- Trial name
- NCT07515456
- Testing
- Theophylline, Sumatriptan, Gabapentin
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Tanta University
Transcatheter Aortic Valve Replacement
Ultrasound-guided Femoral Puncture to Reduce Access- Related Complications After TAVR: (ACCESS-TAVR SIRIO)
Recent observational data showed a marked reduction of vascular and bleeding complications by the use of ultrasound(US)-guided femoral artery puncture to gain the vascular access and guide the implantation of the Perclose…
- Trial name
- NCT05637983
- Testing
- US-guided femoral puncture vs Fluoroscopy-guided puncture
- Where
- Italy
- Volunteers
- 508 people
- Sponsor
- Fondazione Toscana Gabriele Monasterio
Allergy
Development and Evaluation of an Artificial Intelligence Model for the Diagnosis of Aeroallergies
To improve accuracy and take out human error, Hippo Dx previously developed S.P.A.T., an automated skin prick test. Now, Hippo Dx will develop and evaluate a S.P.A.T.
- Trial name
- SPAT_AI (NCT05918354)
- Testing
- Skin Prick Automated Test
- Where
- 6 sites in Belgium, Germany
- Volunteers
- 993 people
- Sponsor
- Hippocreates
Atrial Fibrillation
Three Dimensional Navigation IntraCardiac Guidance Kit for Atrial Septal Puncture
This study aims to evaluate the safety and efficacy of a three-dimensional navigation intracardiac guidance kit to perform atrial septal puncture in patients requiring catheter ablation, which will be compared with procedures…
- Trial name
- NCT06188351
- Testing
- Three-Dimensional Navigation Atrial Septal Puncture, Conventional Atrial Septal Puncture
- Where
- China
- Volunteers
- 136 people
- Sponsor
- Tongji Hospital
Laparoscopic Entry Technique
A Comparison of Three Different Entry Points to Establish the Pneumoperitoneum
The Palmer's point and periumbilical region are the common laparoscopic entry site to establish the pneumoperitoneum. In the present study, the investigators assess the safety and feasibility of Meng's point as a new laparoscopic…
- Trial name
- NCT02804529
- Testing
- Veress needle
- Where
- China
- Volunteers
- 90 people
- Sponsor
- China-Japan Friendship Hospital
Ventricular Tachycardias, Myocardial Infarction (MI)
Endo-ePIcardial Versus Endocardial Only Catheter Ablation for ISchemic Driven Ventricular Tachycardia (EPISODE VT)
The EPISODE VT trial is designed to compare efficacy and safety of two modalities for interventional treatment - endocardial ablation and endo-epicardial ablation in a population of patients with post myocardial infarction (ICD…
- Conditions
- Ventricular Tachycardias, Myocardial Infarction (MI), Implantable Cardiac Defibrillator, Ablation
- Trial name
- EPISODE_VT (NCT07240441)
- Testing
- Endocardial VT ablation, Endo-epicardial VT ablation
- Where
- 9 sites in Poland
- Volunteers
- 220 people
- Sponsor
- MEDICOVER SP Z O.O.
Mitral Regurgitation
Double Transseptal Guide Sheath to Prevent Dock Drop During SAPIEN M3 Transcatheter Mitral Valve Replacement
This study looks at a heart procedure called transcatheter mitral valve replacement. Doctors use a device called SAPIEN M3 to replace a damaged heart valve.
- Trial name
- DGS-M3 (NCT07878195)
- Where
- Austria
- Volunteers
- 77 people
- Sponsor
- Medical University of Vienna
Pediatric Lumbar Puncture
Intravenous Fluid Administration's Effect on Pediatric Lumbar Puncture
The purpose of this project is to determine if administration of normal saline intravenous fluids prior to a lumbar puncture improves first time success of lumbar puncture in infants less than 3 months of age.
- Trial name
- NCT05302765
- Testing
- Normal Saline Intravenous Fluids
- Where
- United States
- Volunteers
- 182 people
- Sponsor
- University of Alabama at Birmingham
Pseudotumor Cerebri
Optic Nerve Sheath Diameters in Idiopathic Intracranial Hypertension Patients
Idiopathic intracranial hypertensionis a type of increased intracranial pressure. Diagnosis is made by lumbar puncture, which is an invasive technique.
- Trial name
- NCT04603118
- Testing
- Optic ultrasonography, Lumbar puncture
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Ege University
Allergy
Sensitivity and Specificity of 3 Solutions of Allergen Extract for Diagnosis by Skin Prick Testing
A Phase III study to determine the sensitivity and specificity of three solutions of different allergen extracts for diagnosis by skin prick-test: 5 Grasses pollen, Birch pollen, Dermatophagoides pteronyssinus mite
- Trial name
- NCT01964768
- Testing
- Skin prick-test
- Volunteers
- 324 people
- Sponsor
- Stallergenes Greer
Post-Dural Puncture Headache
Comparison of Nebulized Neostigmine/Atropine Versus Lignocaine in Treating Acute Post-dural Puncture Headache Following Subarachnoid Block in Parturient Undergoing Elective Cesarean Section. A Randomized, Clinical Trial.
Post-dural puncture headache (PDPH) is a common and debilitating complication of spinal anesthesia in pregnant patients undergoing cesarean sections, with an incidence ranging from 0.5% to 2% (1).
- Trial name
- NCT06824025
- Testing
- lidocaine group ( nebulized lidocaine + saline) total volume 4 ml
- Where
- Egypt
- Volunteers
- 111 people
- Sponsor
- Minia University