Clinical trials: Puncture Skin
Allergic Rhinitis, Asthma
Randomized Evaluation of Ten Allergy Skin Prick Test Devices
The goal of this study is to compare ten current and readily available FDA approved allergy skin prick devices to determine the most sensitive and specific product and methods used for the diagnosis of allergic disease.
- Conditions
- Allergic Rhinitis, Asthma, Food Allergy, Skin Testing
- Trial name
- NCT03509766
- Testing
- Histamine skin testing
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Rhinitis, Allergic, Perennial, Rhinitis, Allergic, Seasonal
Optimal Concentration of Dermatophagoides Pteronyssinus (Dp) Allergen Extract for Skin Prick Test (SPT) of Thai Population
The purpose of this study is to determine the appropriate concentration of diagnostic reagent of house dust mite (Dp) to be used in diagnostic allergy skin prick test among Thai population with allergic rhinitis.
- Conditions
- Rhinitis, Allergic, Perennial, Rhinitis, Allergic, Seasonal, Skin Prick Test
- Trial name
- DSPT (NCT01172613)
- Where
- 2 sites in Thailand
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Siriraj Hospital
Peanut Allergy
Evaluation of Allergenicity of Hypoallergenic Peanut Product in Peanut Allergic Subjects
This is a proof of concept study to determine the safety and allergenicity of hypoallergenic peanut product extract as compared to standard peanut extract in an adult population with known peanut allergy.
- Trial name
- peanut (NCT01489514)
- Testing
- Epicutaneous skin prick testing
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Allergy to Grass Pollen (Secale Cereale)
Biological Standardization of Secale Cereale Allergen Extract
The objective of this study is to determine the biologic activity of a Secale cereale allergen extract in histamine equivalent prick (HEP) units, in order to be used as in-house reference preparation (IHRP).
- Trial name
- NCT01408238
- Testing
- Four different concentrations of Secale cereale allergen extract, positive control and negative control
- Where
- 2 sites in Spain
- Volunteers
- 35 people
- Sponsor
- Laboratorios Leti, S.L.
Asthma
A Study of Efficacy of New Doses of Xolair to Protect From Allergen Challenge in Groups of Asthma Patients Defined by IgE Levels
This study was intended to demonstrate that patients with standard and high immunoglobulin E (IgE) levels can be protected from allergen induced broncho-constriction by Xolair
- Trial name
- NCT00624832
- Testing
- Xolair
- Where
- 6 sites in Germany, Netherlands and 1 more
- Volunteers
- 60 people
- Sponsor
- Novartis
Breast Cancer
Can Methylprednisoloneacetate Prevent Seroma After Mastectomy for Primary Breast Cancer
A randomised double-blinded study, in which the patients either get methylprednisoloneacetate or saline solution in the mastectomy cavity to evaluate the efficacy of methylprednisoloneacetate in preventing seroma in patients…
- Trial name
- NCT01380912
- Testing
- methylprednisoloneacetate
- Where
- 2 sites in Denmark
- Volunteers
- 160 people
- Sponsor
- Copenhagen University Hospital at Herlev
Migraine
Influence of Ubrogepant and Sumatriptan on the Dermal Blood Flow Response to Histamine, Cinnamaldehyde and Capsaicin
The involvement of calcitonin gene-related peptide (CGRP) in the cinnamaldehyde-induced dermal blood flow increase and in the mechanism of action of triptans will be investigated.
- Trial name
- NCT05654298
- Testing
- Sumatriptan, Ubrogepant
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Allergy Pollen, Allergic Reaction
Phleum Pratense and Dactylis Glomerata Allergen Extracts Standardization
The primary objective is to assess the concentration of each allergen extract (Phleum pratense and Dactylis glomerata) that induces a wheal size equivalent to that produced by a 10 mg/mL histamine dihydrochloride solution.
- Conditions
- Allergy Pollen, Allergic Reaction, Allergic Skin Reaction
- Trial name
- NCT06957496
- Testing
- Allergenic extracts
- Where
- Spain
- Volunteers
- 31 people
- Sponsor
- Inmunotek S.L.
Allergy Pollen
Microassay and Allergy Skin Prick Test Correlation Study
The purpose of this study is to evaluate the potential correlation of the results of allergen-specific skin prick tests (SPT) to that of allergen-specific microarray determination (microassay test).
- Trial name
- NCT03514303
- Testing
- Spiriplex Allergenex Microassay
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- United Allergy Services
Atopic Dermatitis, Probiotics
Effect of Probiotics in the Atopic Dermatitis
This study was designed to evaluate the efficacy of probiotics in the treatment of atopic dermatitis. Probiotics in AD patients were effective in reducing SCORAD index levels, but not effective in skin prick test positivity…
- Trial name
- NCT01224132
- Testing
- probiotic ® pur
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Type I Hypersensitivity
Investigation of Safety+Efficacy of Different Doses of RagweedMATAMPL;Assessment of Residual Allergenicity Using Skin Prick Test
The purpose of this study is to assess the immunological differences between three RagweedMATAMPL treatment arms compared to placebo with respect to immunoglobulin levels.
- Trial name
- NCT00258635
- Testing
- RagweedMATAMPL
- Where
- 4 sites in United States
- Volunteers
- 69 people
- Sponsor
- Allergy Therapeutics
Healthy Adult
This Study Evaluates Skin Response Following Application of a Collagen-based Material in Healthy Adult Volunteers Using a Standardized Skin Prick Test. Skin Responses Will be Assessed at Multiple Time Points Following Application, and the Study is Intended to Evaluate Dermal Safety.
This study evaluates the allergic (immunogenic) response following application of a collagen-based material in healthy adult volunteers using a standardized skin prick test.
- Trial name
- SPT (NCT07473674)
- Testing
- Collagen Matrix Skin Prick Test Device
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- SerenaGroup, Inc.
Sensitization to Legumes
Prevalence of Sensitization to Legumes in a Region From Southern France (Légumineuses)
The Mediterranean diet is a model for health. Indeed, according to some epidemiological studies, it would participate in the prevention of various diseases such as cardiovascular diseases, diabetes type 2, cancer and obesity.
- Trial name
- Légumineuses (NCT03686891)
- Testing
- Skin prick tests with four native legumes
- Where
- France
- Volunteers
- 2,000 people
- Sponsor
- University Hospital, Montpellier
Allergy Skin Prick Test Reading
Digital Device Reading Skin Prick Test
Skin prick tests (SPTs), or intraepidermal tests, are the first diagnostic approach for people with a suspected allergy. SPTs are very simple, safe and quick.
- Trial name
- NCT06743737
- Testing
- Digital skin test reading device
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Type I Hypersensitivity
Assessment of Residual Allergenicity of Tree (Birch, Hazel, and Alder) Pollen Allergoid Using Skin Prick Testing
The purpose of this study is to evaluate the residual allergenicity of Tree MATA (modified pollen allergen tyrosine adsorbate) by skin prick testing.
- Trial name
- NCT00107705
- Testing
- Tree MATA MPL
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Allergy Therapeutics
Pain, Anxiety
Effect of Virtual Reality and Serious Games on Pain, Fear, Anxiety, and Satisfaction During Skin Prick Testing in Children
This randomized controlled trial evaluated the effectiveness of virtual reality (VR) and serious gaming (SG) in reducing pain, fear, and anxiety, and improving satisfaction during skin prick testing (SPT) in children aged 6-12…
- Conditions
- Pain, Anxiety, Fear, Allergy
- Trial name
- NCT06993259
- Testing
- Virtual Reality, Serious game
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Trakya University
Hay Fever
Evaluation of High Speed Laser Doppler Imaging Technology
Skin prick tests (SPT) are commonly used in daily allergological practice to assess skin reactivity to allergens. Multiple factors can contribute to non-optimal results of conventional wheal and flare measurement (CWFM) of SPT…
- Trial name
- HSL-DI (NCT02619331)
- Testing
- Allergy test reading
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Immediate Hypersensitivity
Comparison Between spIgE and Skin Prick Test of Local and Imported Aeroallergens
The prevalence of Allergic rhinitis(AR) and asthma was increased world wide. In 1998, ISAAC found that prevalence of AR and asthma inThailand was in moderately high group.
- Trial name
- NCT02561390
- Testing
- Skin prick test, specific IgE measurement
- Where
- Thailand
- Volunteers
- 84 people
- Sponsor
- Mahidol University
Vitiligo, Non-segmental Vitiligo
Comparison of Needling and Microneedling Plus Phototherapy in Localized Vitiligo Patients
This randomized controlled trial aims to compare the efficacy of needling versus microneedling, both followed by narrowband UVB therapy, in achieving repigmentation in patients with localized stable non-segmental vitiligo.
- Trial name
- NCT06991972
- Testing
- Needling + NBUVB, Microneedling + NBUVB
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Khyber Teaching Hospital
Pain
Association With Spinal Needle-puncture Pain and Menstrual Phase
This prospective observational study aimed to evaluate the relationship between menstrual phase cycles and spinal needle-puncture pain during spinal anesthesia in female patients of reproductive age.
- Trial name
- NCT05481255
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Konya Meram State Hospital