Clinical trials: Quadriceps Atrophy
ICU Acquired Weakness, Quadriceps Muscle Atrophy
Ultrasound Measurement of Quadriceps Shortening During Neuromuscular Electrical Stimulation in Critically Ill Patients
ICU-Aw is highly prevalent (50%) among critically ill patients. Its diagnosis is usually delayed as it requires patients' awakening and collaboration to provide accurate measurement.
- Trial name
- DETECT (NCT04722445)
- Testing
- Early ultrasound measurement of quadriceps shortening during neuromuscular electrical stimulation (NMES)
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Groupe Hospitalier du Havre
Anterior Cruciate Ligament Rupture, Quadriceps Muscle Atrophy
Blood Flow Restriction After Anterior Cruciate Ligament Reconstruction (ACLR)
Muscle strength and muscle volume decrease rapidly with the immobilization process after sports-related injury and surgery. Depending on the decrease in muscle strength and muscle volume, functional performance also deteriorates…
- Trial name
- ACLR (NCT05500872)
- Testing
- Cross-education and blood flow restriction training, Cross-education
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Hacettepe University
Cancer, Post-cancer
Correlation Between Ultrasound-assessed Quadriceps Muscle Mass and Baseline Whole-body Densitometry Muscle Index in the Post-cancer Population (JUMP Research II)
Therapeutic advances in oncology have transformed the prognosis of cancer patients, placing a significant number of them either in a context of recovery or in prolonged remission close to a chronic disease.
- Conditions
- Cancer, Post-cancer, Hematology
- Trial name
- JUMPresearchII (NCT06007794)
- Testing
- JUMP group
- Where
- France
- Volunteers
- 55 people
- Sponsor
- Hospices Civils de Lyon
Sarcopenia in Elderly
Muscle Strength Asymmetry In Sarkopenic And Non-sarcopenic Older Adults
The purpose of this observational study is to examine whether differences in muscle strength between the dominant and non-dominant sides of the body are associated with sarcopenia in older adults.
- Trial name
- NCT07414888
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
COPD, Quadriceps Muscle Atrophy
Clinimetric Properties of Muscle Mass and Stiffness Measurements of the Quadriceps in Patients With COPD
A large amount of patients with COPD suffer from muscle dysfunction characterized by losses of muscle mass and strength. Studies have shown an association between a loss of quadriceps muscle mass and premature death.
- Trial name
- Metriquad (NCT06994689)
- Testing
- Perimetry and ShearWave measurement of the quadriceps muscle before and after a pulmonary rehabilitation (PR) programme
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Groupe Hospitalier du Havre
Muscle Atrophy
Effectiveness of the Kinesio Taping® in Muscle Activation
Forty-eight female patients will be randomized into three groups to receive the Kinesio taping, placebo Kinesio taping and control group. The group Kinesio taping receive the correct application of the method described.
- Trial name
- EKTAQRIH (NCT01991171)
- Testing
- Kinesio Taping
- Where
- Brazil
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Paulista University
Muscle Weakness, Quadriceps Muscle Atrophy
NM Balance Regulation With ULLS and Loss of Sleep
The goal of this trial is to learn about how restricted sleep and not bearing weight on the leg affects muscle strength and posture control.
- Conditions
- Muscle Weakness, Quadriceps Muscle Atrophy, Sleep Disturbance
- Trial name
- NCT05956964
- Testing
- Sleep Restriction, Sleep Adequate
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Lance Bollinger
Osteoarthritis, Knee, Anterior Cruciate Ligament Injuries
Vibration and Post-traumatic Osteoarthritis Risk Following ACL Injury
The goal of this randomized clinical trial is to evaluate the effects of vibration on factors related to the risks of post-traumatic knee osteoarthritis and secondary anterior cruciate ligament (ACL) injury in individuals who…
- Conditions
- Osteoarthritis, Knee, Anterior Cruciate Ligament Injuries, Post-traumatic Osteoarthritis, Quadriceps Muscle Atrophy
- Trial name
- NCT04875052
- Testing
- Experimental: Whole Body Vibration, Experimental: Local Muscle Vibration, Standard ACL Rehabilitation
- Where
- 2 sites in United States
- Volunteers
- 114 people
- Sponsor
- University of North Carolina, Chapel Hill
Muscle Loss
Plyometric Exercises Versus Isometric Exercises With Theraband Elastic Band in Water Polo Players
Introduction: The improvement of strength affects muscle volume, dynamic stability and sports performance in water polo athletes.
- Trial name
- NCT03872076
- Testing
- Experimental, Control
- Where
- Spain
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Investigación en Hemofilia y Fisioterapia
Muscle Fiber Atrophy, Type II
The Effect of Neuromuscular Electrical Stimulation (NMES)
The purpose of this project is to test the effectiveness of neuromuscular electrical stimulation (NMES) that produces 40 % of maximum voluntary contraction (MVC) in increasing muscle size and improvement in muscle force output…
- Trial name
- NMES (NCT00765739)
- Testing
- Neuromuscular electrical stimulation, voluntary strengthening exercise
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Abdominal Obesity, Cardiac Disease
Effects of Different Dietary Interventions on Abdominal Fat Components, Quadriceps Muscles and Cardiometabolic Parameters
The study aims to evaluate the impact of different dietary interventions on body composition (abdominal fat components and quadriceps muscles) and cardiometabolic parameters.
- Conditions
- Abdominal Obesity, Cardiac Disease, Metabolic Disease, Cardiometabolic Syndrome
- Trial name
- NCT06320782
- Testing
- Calorie restriction and balanced distribution of macronutrients, Calorie restriction and low-carbohydrate diet, Calorie restriction and low-fat diet
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Pernambuco
Sepsis, Critical Illness
Indirect Calorimetry Usage and Effect in Ventilator-free Days and Muscle Thickness in Septic Ventilated Patients
Patients admitted to the ICU with diagnosis of sepsis and requiring mechanical ventilation for at least 24-hours and receiving enteral or parenteral nutrition will be prospectively randomized to one of two arms.
- Conditions
- Sepsis, Critical Illness, Respiratory Failure, Nutrition Disorders
- Trial name
- NCT03440593
- Testing
- Caloric delivery will target results of IC measurement.
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Baylor Research Institute
COPD - Chronic Obstructive Pulmonary Disease, Muscle Atrophy
Progressive Resistance Training of the Extensor Muscle of the Thigh in COPD-patients Hospitalized With an Exacerbation
We want to test the hypothesis, that resistance training by the use of weigth cuffs on the angle can prevent loss or improve the strength of the quadriceps muscle in COPD patients admitted to hospital due to an exacerbation.
- Trial name
- NCT01812460
- Testing
- Intervention-training-group
- Where
- Denmark
- Sponsor
- Frederikssunds Hospital, Denmark
ACL Injury, Quadriceps Muscle Atrophy
BFR Therapy After ACL Reconstruction
This study is a prospective, double-blinded, randomized control trial examining the effect of blood flow restriction (BFR) therapy on reducing post-operative quadriceps atrophy in patients undergoing anterior cruciate ligament…
- Trial name
- BFR (NCT03794570)
- Testing
- Blood flow restriction therapy - with Delfi Personalized Tourniquet System
- Where
- United States
- Sponsor
- Steadman Philippon Research Institute
Muscle Atrophy, Proximal, Muscle Atrophy
Ultrasound for Rectus Femoris Measurement
Postoperative protocols for orthopedic procedures on the lower limb often require a period of immobilization to protect the surgical site.
- Conditions
- Muscle Atrophy, Proximal, Muscle Atrophy, ACL Tear, Quadriceps Muscle Atrophy
- Trial name
- NCT04105816
- Testing
- 892.1550 Ultrasonic pulsed doppler imaging system, Thigh circumference measurement
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Robert Westermann
Age-Related Atrophy, Physical Disorder
Efficacy of Neuromuscular Electrical Stimulation in Geriatric Population
The decline in physical function and strength was seen by the nature of aging. The older adults often complain of fatigue. For these reasons, proper rehabilitation approaches should be used to ensure healthy life and to keep the…
- Trial name
- NCT03409575
- Testing
- 5 minutes stimulation, 10 minutes stimulation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Sevim ACARÖZ CANDAN
Anterior Cruciate Ligament Injuries, Quadriceps Muscle Atrophy
The Effects of Whole-body Vibration on Increasing Quadriceps Strength in Patients With ACL Ruptures
Introduction: Approximately 35% patients can not return to sports after anterior cruciate ligament reconstruction(ACLR). Persistent quadriceps weakness is a factor that prevents patients return to sports.
- Trial name
- NCT04988828
- Testing
- Whole body vibration
- Where
- Hong Kong
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Knee Arthroscopic Surgery, Arthrogenic Muscle Inhibition
Blood Flow Restriction Training in Knee Arthropathy
Arthrogenic muscle inhibition (AMI) is the key neurophysiological cause of impeding quadriceps activation following anterior cruciate ligament reconstruction (ACLR).
- Conditions
- Knee Arthroscopic Surgery, Arthrogenic Muscle Inhibition, Quadriceps Muscle Weakness
- Trial name
- NCT07837154
- Testing
- Blood flow restriction training with 60%-80% occlusion
- Where
- China
- Volunteers
- 56 people
- Sponsor
- Yuxiu Ji
Quadriceps Muscle Atrophy, Tourniquet
Evaluation of Ischemia and Reperfusion Interval With Neuromonitorization in Tourniquet Application
The goal of this clinical trial is to compare two differential tourniquet pressure in lower extremity surgery cases. The main questions it aims to answer are: What are the perioperative neurophysiological effects of ischemia and…
- Conditions
- Quadriceps Muscle Atrophy, Tourniquet, EMG
- Trial name
- NCT05926154
- Testing
- Surgical tourniquet pressure selection
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Istanbul University
Anterior Cruciate Ligament Injuries, Quadriceps Muscle Atrophy
The Effect of PEMF for Patients With Quadriceps Muscle Weakness After ACLR
In Hong Kong, over 3000 Anterior Cruciate Ligament Reconstructions (ACLR) are performed each year in order to restore knee function after an ACL injury. The ultimate goal of ACLR is to fulfil the return-to-play (RTP) criteria.
- Trial name
- NCT05184023
- Testing
- Pulse Electromagnetic Field
- Where
- Hong Kong
- Volunteers
- 80 people
- Sponsor
- Chinese University of Hong Kong