Clinical trials: Quadriceps Muscle Weakness
ICU Acquired Weakness
Respiratory and Quadriceps Muscle Fatigability After an ICU Acquired Weakness
Muscle dysfunction can be lead to poor outcomes moreover ICU muscle weakness recovery are not correctly described. The investigators aimed to assess the ability for quadriceps or respiratory muscles to repeat an effort at a…
- Trial name
- NCT05396066
- Testing
- Muscle evaluation
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Groupe Hospitalier du Havre
Critical Illness, Respiratory Failure
Treatment of Muscle Weakness in Critically Ill Patients
Patients who are admitted to the intensive care unit and require mechanical ventilation frequently develop profound respiratory and limb muscle weakness.
- Conditions
- Critical Illness, Respiratory Failure, Myopathy, Weakness
- Trial name
- NCT02247895
- Testing
- Electrical stimulation
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Gerald Supinski
Muscle Weakness, Anterior Cruciate Ligament Rupture
Does Gabapentin Reduce Quadriceps Muscle Weakness After Anterior Cruciate Ligament Reconstruction?
Anterior cruciate ligament (ACL) injury is a common sport injury in both professional and recreational athletes. Furthermore, persistent quadriceps weakness and wasting are frequently observed after anterior cruciate ligament…
- Trial name
- NCT03496389
- Testing
- Gabapentin, Tramadol, Panadol
- Volunteers
- 30 people
- Sponsor
- Hospital Authority, Hong Kong
Anterior Cruciate Ligament Injuries, Knee Injuries
Effects of Early Rehabilitation Using Blood Flow Restriction and/or Surface Electromyography Biofeedback on Quadriceps Activation and Strength After Anterior Cruciate Ligament Reconstruction: A Multicenter Randomized Controlled Trial
Many patients experience quadriceps inhibition after anterior cruciate ligament (ACL) reconstruction, delaying strength recovery, hindering return to sport, and potentially increasing the risk of re-injury.
- Conditions
- Anterior Cruciate Ligament Injuries, Knee Injuries, Muscle Weakness
- Trial name
- NCT07145606
- Testing
- Standard Rehabilitation, Blood Flow Restriction (BFR) Training, sEMG Biofeedback
- Where
- 4 sites in France, Switzerland
- Volunteers
- 200 people
- Sponsor
- Haute Ecole ARC Sante
ACL Injury, Sport Injury
Muscular Activations During Eccentric Quadriceps Exercises
The aim of this study is to investigate muscular activations during various quadriceps exercises commonly used in clinical settings.
- Conditions
- ACL Injury, Sport Injury, Sports Physical Therapy, Muscle Weakness
- Trial name
- NCT06162130
- Testing
- Eccentric quadriceps exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Ordu University
Burns, Muscle Weakness
Reallocating Rehabilitation Time to Wii Fit or Pilates After Lower-Limb Burn Injury
This randomized controlled trial will evaluate whether reallocating part of a fixed-duration supervised rehabilitation session to Wii Fit or Pilates will improve functional outcomes in adults with healed lower-extremity burns.
- Conditions
- Burns, Muscle Weakness, Exercises, Functional Performance
- Trial name
- NCT06081504
- Testing
- Wii fit exercises program, Pilates exercises program, Standard physical therapy program
- Where
- 2 sites in Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Weakness
Effect of All-Stim 2 Quadriceps Treatments on Limb Muscle Strength In Mechanically Ventilated Patients
Patients that are on mechanical ventilators in medical intensive care units (MICU) have extremely weak leg muscles. Currently there is no treatment to prevent or reverse this weakness.
- Trial name
- NCT02332187
- Testing
- Active electrical stimulation using an All Stim stimulator
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Gerald Supinski
Pneumatic Tourniquet, Muscle Weakness
Effect of Tourniquet Use on Muscle Thigh Function.
The use of a pneumatic tourniquet with the purpose of maintaining an operative field free of blood is a common practice in orthopedic surgery.
- Trial name
- NCT03473106
- Testing
- Pneumatic tourniquet use
- Where
- Chile
- Volunteers
- 30 people
- Sponsor
- University of Chile
Patellofemoral Pain Syndrome
Muscle Strength Loss and Its Effect on Knee Cap Motion in Volunteers With Anterior Knee Pain
Background: Researchers are interested in how the muscles affect the movement of the knee cap. These muscles may be related to different kinds of knee pain that are not caused by an injury or a disease.
- Trial name
- NCT01862731
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Knee Osteoarthritis, Knee Arthritis
Rate of Torque Development and Voluntary Quadriceps Activation in Patients With Knee Osteoarthritis: A Quantitative Analysis Before and After a Single Session of Manual Physical Therapy
This is a randomized control trial to determine if there is a measurable change in voluntary quadriceps activation, RTD, pain, and function before and after a single session of manual physical therapy.
- Conditions
- Knee Osteoarthritis, Knee Arthritis, Knee Pain Chronic, Knee Deformity
- Trial name
- NCT04234282
- Testing
- Manual Physical Therapy
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Jennifer Moreno Clinic
Intensive Care Unit Acquired Weakness, Muscle Weakness
Early Assessment of Quadriceps Muscle Recovery by Dynamometry and 3D Ultrasound in Intensive Care Patients Under Invasive Mechanical Ventilation
Patients in intensive care often develop acquired muscle weakness (ICUAW or Intensive Care Unit Acquired Weakness) due to immobilization and muscle atrophy.
- Trial name
- DYNAMOREA (NCT07069959)
- Testing
- Early assessment of quadriceps muscle strength
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Nantes University Hospital
ICU Acquired Weakness
Evaluation of Diaphragmatic Function and Quadriceps Muscle Thickness in Patients Receiving High Protein Nutrition
Different Protein Doses' Effect on Diaphragmatic Function and Quadriceps Thickness
- Trial name
- NCT06025760
- Testing
- patients who will receive 2 gm protein/kg/day will be evaluated by ultrasound for diaphragmatic function and quadriceps muscle thickness
- Volunteers
- 32 people
- Sponsor
- Zagazig University
Muscle Strength, Muscle Weakness
Performance Output With Haptics - Evaluating Athlete Response and Unrealized Potential
This minimal risk, randomized, double-blind, placebo controlled Institutional Review Board (IRB)-approved observational study with functional measurements, will evaluate athletic performance after use of a drug- free…
- Trial name
- POWER-UP (NCT06430879)
- Testing
- VICTORY PATCH
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- SuperPatch Limited LLC
Stroke, Hemiparesis
Quadriceps Muscle Activity and Gait Kinematics in Patients With Post-Stroke Stiff-Knee Gait Compared With Healthy Controls
Stiff-knee gait (SKG) is a frequent gait abnormality in people with post-stroke hemiparesis and is characterized by insufficient knee flexion during the swing phase of walking.
- Trial name
- FW QUADRI (NCT07857967)
- Where
- Luxembourg
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Frédéric Chantraine
Knee Arthroscopic Surgery, Arthrogenic Muscle Inhibition
Blood Flow Restriction Training in Knee Arthropathy
Arthrogenic muscle inhibition (AMI) is the key neurophysiological cause of impeding quadriceps activation following anterior cruciate ligament reconstruction (ACLR).
- Conditions
- Knee Arthroscopic Surgery, Arthrogenic Muscle Inhibition, Quadriceps Muscle Weakness
- Trial name
- NCT07837154
- Testing
- Blood flow restriction training with 60%-80% occlusion
- Where
- China
- Volunteers
- 56 people
- Sponsor
- Yuxiu Ji
Muscle Weakness
Effect of Mode of Femoral Nerve Analgesia on Quadriceps Muscle Strength
Quadriceps muscle strength is an important determinant of quality of recovery in elderly patients after total knee arthroplasty.
- Trial name
- NCT02007850
- Testing
- ropivacaine
- Where
- South Korea
- Volunteers
- 36 people
- Sponsor
- Seoul National University Hospital
Muscle Weakness After Anterior Cruciate Ligament Reconstruction
Contralateral Strength-training After Anterior Cruciate Ligament (ACL) Reconstruction
The main aims of the study are (1) to examine the impact of contralateral strength training on the quadriceps muscle function after ACL surgery and (2) to compare the magnitude of cross-education induced by NMES versus eccentric…
- Trial name
- NCT01901965
- Testing
- Neuromuscular electrical stimulation, eccentric training
- Where
- Switzerland
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Schulthess Klinik
Foot Drop, Thigh Muscles Weakness (Hamstrings or Quadriceps)
Evaluation of the Safety and Performance of the NESS L300 Plus System
The study is designed to evaluate the safety and efficacy of using the L300 Plus as a neuroprosthesis device for walking in patients following an UMN injury or disease.
- Conditions
- Foot Drop, Thigh Muscles Weakness (Hamstrings or Quadriceps), Upper Motor Neuron Injury or Disease
- Trial name
- L300Plus (NCT01237860)
- Testing
- NESS L300 Plus System
- Where
- Israel
- Volunteers
- 45 people
- Sponsor
- Bioness Inc
Muscle Weakness, Quality of Life
The Impact of Early Mobilization Protocol in Patients in the ICU
Advances in intensive care and mechanical ventilation (MV) in the past two decades have increased critically ill patient survival.
- Conditions
- Muscle Weakness, Quality of Life, Weaning Acceleration, ICU Length of Stay
- Trial name
- NCT01769846
- Testing
- Early mobilization protocol
- Where
- Brazil
- Volunteers
- 28 people
- Sponsor
- Universidade Federal de Santa Maria
Pain, Postoperative, Muscle Weakness
Low-Volume Pericapsular Nerve Group (PENG) Block With Dexamethasone vs Standard-Volume PENG Block After Total Hip Arthroplasty
The goal of this clinical trial is to compare two regimens of the pericapsular nerve group (PENG) block, an ultrasound-guided injection of local anaesthetic targeting the nerves supplying the front of the hip joint, for…
- Conditions
- Pain, Postoperative, Muscle Weakness, Arthroplasty, Replacement, Hip
- Trial name
- NCT07855341
- Testing
- Pericapsular nerve group (PENG) block, Bupivacaine, Dexamethasone
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University