Clinical trials: Quality of Life
Cancer Of Prostate, Prostate Neoplasms
Highly Conformal, Hypofractionated, Focally Dose Escalated Post-Prostatectomy Radiotherapy
Background: Sometimes prostate cancer comes back after a person's prostate is removed. In this case, radiation is a common treatment. Radiation kills prostate cancer cells. It can be very effective.
- Conditions
- Cancer Of Prostate, Prostate Neoplasms, Prostate Cancer, Neoplasms of Prostate
- Trial name
- NCT03388619
- Testing
- Prostate bed with integrated boost, Prostate bed irradiation only, Whole Body Bone Scan
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Cancer Institute (NCI)
Frail Older Adults
CogXergaming to Promote Physical Activity and Cognitive Function in Frail Older Adults
Due to the age associated sarcopenia and reduced cardiovascular fitness, frail older adults experience significant decrease in physical function which comprises of mobility, endurance, muscle strength and balance control.
- Trial name
- NCT04534686
- Testing
- CogXergaming, Matter of Balance Training
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- University of Illinois at Chicago
Overweight and Obesity, Physical Activity
Implementation and Evaluation of a Before School Physical Activity Program in Revere, MA
This study evaluates the implementation of the BOKS program in three schools (K-8) in Revere, MA, and its effect on participating students with regard to BMI, cognitive, and quality of life outcomes.
- Conditions
- Overweight and Obesity, Physical Activity, Quality of Life, Fitness
- Trial name
- NCT03805295
- Testing
- BOKS Program
- Where
- United States
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Cystic Fibrosis
Sildenafil Exercise: Role of PDE5 Inhibition
Exercise intolerance is an understudied phenomenon in people with CF. The investigators hypothesized that vascular dysfunction plays a significant role, and can be partially reversed by administration of the phosphodiesterase…
- Trial name
- NCT04039087
- Testing
- Sildenafil 40mg oral capsule
- Where
- 2 sites in United States
- Volunteers
- 31 people
- Sponsor
- National Jewish Health
Skin Diseases, Telemedicine
Impact of Teledermatology on Health Services Outcomes in the Department of Veterans Affairs
This study compares store and forward teledermatology with the conventional clinic-based consult process. Our primary objective is to determine whether the mean change in quality of life, as rated by the subscale scores and…
- Conditions
- Skin Diseases, Telemedicine, Quality of Life
- Trial name
- NCT00488293
- Testing
- Store and forward teledermatology
- Where
- 2 sites in United States
- Volunteers
- 392 people
- Sponsor
- US Department of Veterans Affairs
Patient Experience, Medical Emergencies
Effectiveness and Clinical Outcomes of Municipal Acute Wards Versus a General Hospital
Demographic changes in the industrialized world are expected to prompt a need for better organized and more efficient health care services.
- Conditions
- Patient Experience, Medical Emergencies, Mortality, Morbidity
- Trial name
- NCT03885206
- Testing
- Level of healthcare services
- Where
- Norway
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Ostfold University College
Stoma
Coloplast DialogueStudy
The main purpose of the study is to document real life experience on SenSura with focus on skin condition and quality of life.
- Trial name
- NCT00626821
- Testing
- SenSura
- Where
- United States
- Volunteers
- 3,017 people
- Sponsor
- Coloplast A/S
Breast Cancer, Head and Neck Cancer
Using Traditional Acupuncture in the Management of Cancer Treatment Related Lymphoedema
RATIONALE: Acupuncture and moxibustion may improve well-being and quality of life in patients with lymphedema caused by breast cancer or head, neck, and throat cancer.
- Conditions
- Breast Cancer, Head and Neck Cancer, Lymphedema
- Trial name
- AMWELL-SL (NCT00828516)
- Testing
- Acupuncture and moxibustion
- Where
- United Kingdom
- Volunteers
- 56 people
- Sponsor
- East and North Hertfordshire NHS Trust
Neuropathic Pain
Effectiveness of rTMS on Pain and Quality of Life in Patients With Cancer Neuropathic Pain. Clinical Trial.
The purpose of this study is to evaluate the effectiveness of Repetitive transcranial magnetic stimulation (rTMS) on pain and quality of life in patients with cancer neuropathic pain.
- Trial name
- NCT05480410
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- Colombia
- Volunteers
- 10 people
- Sponsor
- Fundacion Universitaria Maria Cano
Renal Transplant
Enteric-Coated Mycophenolate Sodium on Quality of Life in Patients With Gastrointestinal Symptoms Related to Mycophenolate Mofetil Therapy After Kidney Transplantation
This open, multi-center randomized controlled study is designed to investigate the quality of life in patients with mycophenolate mofetil (MMF)-induced gastrointestinal (GI) adverse events after converting to enteric-coated…
- Trial name
- NCT00239005
- Testing
- Enteric-Coated Mycophenolate Sodium (EC-MPS), Mycophenolate Mofetil (MMF)
- Where
- United Kingdom
- Volunteers
- 134 people
- Sponsor
- Novartis Pharmaceuticals
Fall Patients, Delirium
Implementation of Multidisciplinary Assessments for Geriatric Patients in an ED Observation Unit
This project will implement a 2 step protocol for multidisciplinary geriatric assessment in the Emergency Department (ED). Candidate: Dr.
- Conditions
- Fall Patients, Delirium, Quality of Life, Functional Status
- Trial name
- IMAGE (NCT04068311)
- Testing
- Geriatric Screening tools
- Where
- United States
- Volunteers
- 373 people
- Sponsor
- Ohio State University
Chronic Hepatitis C
Real World Evidence of the Effectiveness of Paritaprevir/Ritonavir, Ombitasvir, ± Dasabuvir, ± Ribavirin in Patients With Chronic Hepatitis C
This study seeks to provide evidence of the effectiveness and obtain patient reported outcomes (PRO) and work productivity data of the interferon-free regimen of paritaprevir (PTV)/ritonavir (r) + ombitasvir (OBV), +/- dasabuvir…
- Trial name
- NCT02640547
- Volunteers
- 394 people
- Sponsor
- AbbVie
Rosacea
Internet Surveys and Their Impact on Adherence for Rosacea
An investigator-blinded, prospective, 6 month study of subjects with persistent erythema associated with active rosacea will be conducted in 20 subjects aged 18 years and older.
- Trial name
- NCT03048058
- Testing
- brimonidine topical gel 0.33% & survey, brimonidine topical gel 0.33% & SOC
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Wake Forest University Health Sciences
Depression
Effectiveness of Methylphenidate in Improving Cognition and Function in Older Adults With Depression
This study will evaluate the safety and effectiveness of methylphenidate in improving cognition and function in older adults with depression.
- Trial name
- NCT00602290
- Testing
- Citalopram, Methylphenidate (MPH)
- Where
- United States
- Volunteers
- 181 people
- Sponsor
- University of California, Los Angeles
Anxiety, Depressive Symptoms
Stepped-Care Telehealth for Distress in Cancer Survivors
Mental health issues in post-treatment adult cancer survivors are associated with multiple adverse outcomes and may represent a cancer health disparity for rural survivors.
- Conditions
- Anxiety, Depressive Symptoms, Sleep Disturbance, Recurrent Disease
- Trial name
- Telehealth (NCT03060096)
- Testing
- Severe Anxiety/depression: High Intensity Stepped Care, Moderate Anxiety/depression: Low Intensity Stepped care, Enhanced Usual Care Control
- Where
- 166 sites in United States
- Volunteers
- 68 people
- Sponsor
- Wake Forest University Health Sciences
Diabetes, Diabetes Mellitus
QBSAfe: A Novel Approach to Diabetes Management Focused on Quality of Life, Burden of Treatment, Social Integration and Avoidance of Future Events
The purpose of this study is to co-develop a toolkit (known as the QBSAfe toolkit) with patients, family caregivers, and clinicians that focuses on palliating symptoms, alleviating burden of treatment, facilitating social…
- Trial name
- QBSAfe (NCT04514523)
- Testing
- QBSAfe Toolkit
- Where
- 3 sites in United States
- Volunteers
- 91 people
- Sponsor
- Yale University
Pain, Dementia
Music Based Caregiving in Patients With Pain and Dementia
The main objective of this study is to evaluate the pain-relieving effect of a well-characterized non-pharmacological treatment program, music-based caregiving (MBC), to patients in nursing homes with dementia and pain.
- Conditions
- Pain, Dementia, Music, Activity, Motor
- Trial name
- NCT04229446
- Testing
- Music based caregiving
- Where
- 2 sites in Norway
- Volunteers
- 276 people
- Sponsor
- Oslo University Hospital
Osteoarthritis
Prospective Multicenter Non-interventional Study in Patients With Knee or Hip Osteoarthritis Having a Theraflex Treatment
The main purpose of this study is to evaluate how a long-term treatment with Theraflex during 64 weeks affects pain intensity in the affected knee or hip joint, the activity in daily living, the quality of life and patient…
- Trial name
- NCT03330288
- Testing
- Theraflex, BAY 874017
- Where
- 2 sites in Russia
- Volunteers
- 1,102 people
- Sponsor
- Bayer
Pain, Quality of Life
Simultaneous RZV and aIIV4 Vaccination
The overall aim of the study is to compare the safety of simultaneous Zoster Vaccine Recombinant, Adjuvanted (RZV) (SHINGRIX®) and Quadrivalent Influenza Vaccine, Adjuvanted (FLUAD®) versus simultaneous Zoster Vaccine…
- Conditions
- Pain, Quality of Life, Injection Site Reaction, Adverse Drug Event
- Trial name
- NCT05007041
- Testing
- FLUAD® Quadrivalent, Fluzone® High-Dose Quadrivalent, SHINGRIX®
- Where
- 2 sites in United States
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- Duke University
Malignant Tumors
Additive Homeopathy in Cancer Patients
The investigators aim to investigate the validity of their previous results in a randomized prospective, placebo-controlled, double-blind, multicenter controlled evaluation of questionnaires in patients with advanced malignant…
- Trial name
- HIC (NCT01509612)
- Testing
- Additive classical homeopathy
- Where
- Austria
- Volunteers
- 150 people
- Sponsor
- Medical University of Vienna