Clinical trials: Quality of Life (QOL)
ICU Acquired Weakness
Evaluation of FDY-5301 in Major Trauma Patients in ICU
The purpose of this study is to evaluate the efficacy, safety, and pharmacokinetics (PK) of FDY-5301 compared to placebo in major trauma ICU patients at risk of intensive care unit acquired weakness (ICUAW)
- Trial name
- NCT04430283
- Testing
- FDY-5301
- Where
- 5 sites in United States
- Volunteers
- 8 people
- Sponsor
- Faraday Pharmaceuticals, Inc.
Spinal Surgery
Quality of Life, Expectations, Thoughts and Fears of Patients on the Waiting List for Spinal Surgery
The objective of this qualitative prospective observational study is to analyze the cognitive aspect, the emotional-behavioral state and the quality of life of patients during their stay on the waiting list for two categories of…
- Trial name
- chirurgia-1 (NCT06323694)
- Testing
- quality of life
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Istituto Ortopedico Rizzoli
Diabetes Mellitus, Diabetes Mellitus, Type 2
Determinants of Bone and Muscle Quality and Strength in Obesity With and Without Diabetes
Background: Osteoporotic fractures are a major public health issue. They cause substantial disability, loss of autonomy, morbidity and excess mortality.
- Conditions
- Diabetes Mellitus, Diabetes Mellitus, Type 2, Obesity, Body Weight
- Trial name
- BODI2 (NCT04093856)
- Where
- 2 sites in Canada
- Volunteers
- 40 people
- Sponsor
- Suzanne Morin
Oral Cancer
AI-based Physiotherapy for Oral Cancer Patients
This study examines the effects of AI-based physiotherapy on oral function, shoulder function, whole-body physical function, and quality of life in oral cancer patients.
- Trial name
- NCT06785051
- Testing
- AI-based physiotherapy, Conventional physiotherapy, Scar management
- Where
- 2 sites in Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Urticaria
An Open-Label Study of the Effects of Desloratadine (Aerius.) Treatment on the Quality of Life of Patients With Chronic Idiopathic Urticaria (Study P02540)
This open-label study is being conducted to determine the effect of DL treatment for CIU on symptom and disease severity, quality of life, daytime functioning, and quality of sleep.
- Trial name
- NCT00795522
- Testing
- Desloratadine
- Volunteers
- 51 people
- Sponsor
- Organon and Co
Inflammatory Arthritis
Effect of a Self-Management Intervention for Patients Newly Diagnosed With Inflammatory Arthritis: The NISMA Trial
Background: In patients newly diagnosed with inflammatory arthritis, a self-management intervention is anticipated to enhance self-management skills, thereby improving patient function, well-being, and survival.
- Trial name
- NCT06533423
- Testing
- Newly diagnosed with Inflammatory arthritis - a Self-MAnagement intervention (NISMA)
- Where
- 2 sites in Denmark
- Volunteers
- 130 people
- Sponsor
- Glostrup University Hospital, Copenhagen
Urge Urinary Incontinence
The Long Term Outcomes of Rehabilitation and Drug Treatment for in Urgency Urinary Incontinence
Urinary Urge Incontinence (UUI) is the involuntary urine loss associated with a strong sensation to void. UUI usually associated with reduced bladder capacity. The pathophysiology is unclear.
- Trial name
- UUI (NCT00498888)
- Testing
- tolterodine, bladder training, pelvic floor muscle training
- Where
- Israel
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Assuta Hospital Systems
Obesity, Diabetes
Calorie Restriction and Changes in Body Composition, Disease, Function, and Quality of Life in Older Adults
The investigators want to determine if the benefits of weight loss outweigh the potential risk in a group of older adults. The investigators will test the hypothesis that changes in diet composition alone or in conjunction with…
- Conditions
- Obesity, Diabetes, Hypertension, Hyperlipidemia
- Trial name
- CROSSROADS (NCT00955903)
- Testing
- Exercise, Reduced Calorie Diet, Weight Maintenance Diet
- Where
- United States
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Multiple Sclerosis, Constipation
Symptoms and Treatment Assessment of Ano-Rectal Disorders in Multiple Sclerosis Patients : STAR-Q
Multiple sclerosis (MS) is known to cause urinary disorders, sexual and bowel dysfunction. Urinary symptoms due to MS are well known and profit of multiple questionnaire or tool developed in MS patients.
- Conditions
- Multiple Sclerosis, Constipation, Fecal Incontinence
- Trial name
- STAR-Q (NCT04996186)
- Testing
- Clinical interviews
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Pierre and Marie Curie University
Cognitive Therapy
Exploring the Effectiveness of Group Cognitive Stimulation Therapy in People With Schizophrenia.
Background: Cognitive dysfunction is the core defect of schizophrenia, which seriously affects the emotional, social functions and quality of life in people with schizophrenia.
- Trial name
- NCT04916483
- Testing
- group cognitive stimulation therapy, usual care
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- National Yang Ming Chiao Tung University
Kidney Transplantation
Development and Testing of the Kidney BEAM-KIDS Digital Platform for Children After Kidney Transplantation
Children and young people (CYP) with chronic kidney disease (CKD) say that physical activity, school, social activities and tiredness are the main issues they want to improve.
- Trial name
- BEAM-KIDs (NCT05453656)
- Testing
- exercise
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Queen Margaret University
Open Heart Surgery, Life Quality
The Effect of Informing the Relatives of Patients Undergoing Open Heart Surgery
The goal of this type of study clinical trial is to determine the effect of informing the relatives of patients undergoing open heart surgery on the patients; quality of life and caregiver burden.The main question it aims to…
- Conditions
- Open Heart Surgery, Life Quality, Caregiver Burden
- Trial name
- NCT06436872
- Testing
- informing patients with using a booklet
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people
- Sponsor
- Trakya University
Purpura Fulminans
Outcomes of Purpura FULminans in Adults - The hOPeFUL Study
Purpura fulminans (PF) is a rare life-threatening infectious disease characterized by the association of a sudden and extensive purpura together with acute circulatory failure.
- Trial name
- hOPeFUL (NCT03216577)
- Testing
- Phone interview measuring health-related quality of life variables
- Where
- 26 sites in France
- Volunteers
- 74 people
- Sponsor
- Henri Mondor University Hospital
Mukbang
The Association Between Watching Mukbang Videos and the Appetite of Children With Cancer
The purpose of this study is to record the "Mukbang" watching behavior and appetite of children with cancer during inpatient radiotherapy and chemotherapy through intensive longitudinal study, explore their correlation, and the…
- Trial name
- NCT05493020
- Testing
- Questionnaires set
- Where
- China
- Volunteers
- 179 people
- Sponsor
- Sun Yat-sen University
Quality of Life
Quality of Life of Postnatal Mothers Attending Maternal and Child Health Clinic in Biratnagar
Objectives: Assessing health-related quality of life (HRQoL) and its predictors is essential for providing adequate healthcare and developing necessary interventions in women post-delivery.
- Trial name
- QoL (NCT05777382)
- Testing
- inquiry to postnatal mothers
- Where
- Nepal
- Volunteers
- 129 people
- Sponsor
- Tribhuvan University, Nepal
Soft Tissue Sarcoma, Bone Sarcoma
Assessment of the Functional Outcome and Quality of Life in Sarcoma Patients
Primary bone and soft tissue sarcomas are an exceptionally rare form of cancer, collectively accounting for only 1% of all malignancies diagnosed.
- Trial name
- QOLSarcoma (NCT05051059)
- Testing
- Functional outcome, Health related quality of life (HRQoL) assessment
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Frailty, Frailty At Older Adults
ASSESSMENT of FRAILTY AS a PROGNOSTIC FACTOR for MORTALITY, DISABILITY, and QUALITY of LIFE AFTER ICU ADMISSION
Between 30% and 40% of elderly patients (over 70 years old) who require hospitalization and treatment in Intensive Care Units (ICU) exhibit a state of frailty.
- Trial name
- FG-UCI (NCT06793462)
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Quality of Life, Coping
Effects of Multicomponent Exercise on Quality of Life, Coping With Stress, and Well-Being in Older Women
The aim of this study is to evaluate the effects of multi-component exercise on quality of life, coping with stress and well-being in elderly women.
- Conditions
- Quality of Life, Coping, Well-being, Older People
- Trial name
- NCT06849427
- Testing
- multicomponent exercise intervention
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Antalya Bilim University
Adverse Effect of Radiation Therapy
IORT-Boost-Study, Prospective Observational Study for Intraoperative Radiotherapy of the Breast as a Boost
In this study the investigators observe the investigation, whether the new method for Boost-Irradiation with the Intrabeam Device of Zeiss Germany influences local recurrence, acute and late effects of Radiotherapy, overall…
- Trial name
- NCT02114086
- Where
- Switzerland
- Volunteers
- 163 people
- Sponsor
- Kantonsspital Münsterlingen
Posttraumatic Stress Disorder, Depression
A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and Comorbidity
The overarching goal of this UH2-UH3 proposal is to work with the NIH Health Care Systems Research Collaboratory to develop and implement a large scale, cluster randomized pragmatic clinical trial demonstration project that…
- Conditions
- Posttraumatic Stress Disorder, Depression, Alcohol-Related Disorders, Suicidal Ideation
- Trial name
- TSOS6 (NCT02655354)
- Testing
- Motivational Interviewing, Cognitive Behavioral Therapy Elements, Care Management
- Where
- 24 sites in United States
- Volunteers
- 635 people
- Sponsor
- University of Washington