Clinical trials: Quality of Life Impairment
Physical Functional Impairment, Cognitive Impairment
Community Recreation to Enhance Function in Aging
This aim of this study is to examine the therapeutic impacts of a group-based recreational program that delivers guided visual artmaking and dual-task exergaming, to older adults.
- Trial name
- NCT07104435
- Testing
- Artmaking and exergaming
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Quality of Life, Aging
Effects of Functional Training by High Intensity Intervals in Older Adults With Mild Cognitive Impairment.
To analyze the effects of a high intensity interval functional training program (HIFT), in the cognitive and functional capacities of Colombian older adults with mild cognitive impairment.
- Trial name
- NCT04638322
- Testing
- HIFT Group
- Where
- Colombia
- Volunteers
- 52 people
- Sponsor
- University of Jaén
Hearing Impaired
Functioning, Disability, and Quality of Life in the Adult Hearing Impaired
The short-term research objectives of the proposed study are as follows: 1. To measure the effects of audiological intervention on selected domain specific (i.e., Communicative, Interpersonal, and Social roles) and overall…
- Trial name
- NCT00037986
- Testing
- Hearing Aids
- Where
- United States
- Volunteers
- 330 people
- Sponsor
- US Department of Veterans Affairs
Schizophrenia, Schizoaffective Disorder
The Effects of tDCS on Auditory Hallucination, Insight, Neurocognitive Function and HRV in Patients With Schizophrenia
The study aimed to investigate whether transcranial direct current stimulation could modify auditory hallucination, insight, neurocognitive function, heart rate variability, psychosocial functioning and quality of life in…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Auditory Hallucination, Verbal, Neurocognitive Dysfunction
- Trial name
- NCT03388554
- Testing
- tDCS
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Heart Failure, Cardiac Failure
Heart Failure Insomnia Treatment Study
The purpose of this study is to compare a short, behavioral treatment for insomnia with sleep monitoring to determine whether these approaches are effective in reducing insomnia and improving sleep quality among patients with…
- Conditions
- Heart Failure, Cardiac Failure, Congestive Heart Failure, Insomnia
- Trial name
- H-FITS (NCT03636880)
- Testing
- Brief treatment for Insomnia, Sleep Monitoring
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Ohio State University
Urge Urinary Incontinence
The Long Term Outcomes of Rehabilitation and Drug Treatment for in Urgency Urinary Incontinence
Urinary Urge Incontinence (UUI) is the involuntary urine loss associated with a strong sensation to void. UUI usually associated with reduced bladder capacity. The pathophysiology is unclear.
- Trial name
- UUI (NCT00498888)
- Testing
- tolterodine, bladder training, pelvic floor muscle training
- Where
- Israel
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Assuta Hospital Systems
Posttraumatic Stress Disorder, Depression
A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and Comorbidity
The overarching goal of this UH2-UH3 proposal is to work with the NIH Health Care Systems Research Collaboratory to develop and implement a large scale, cluster randomized pragmatic clinical trial demonstration project that…
- Conditions
- Posttraumatic Stress Disorder, Depression, Alcohol-Related Disorders, Suicidal Ideation
- Trial name
- TSOS6 (NCT02655354)
- Testing
- Motivational Interviewing, Cognitive Behavioral Therapy Elements, Care Management
- Where
- 24 sites in United States
- Volunteers
- 635 people
- Sponsor
- University of Washington
Alzheimer Disease, Cognitive Impairment, Mild
Low Level Laser Therapy Impact on Cognitive Function and Quality of Life in Alzheimer Anemic Elderly Patients
Alzheimer's is a type of dementia that affects memory, thinking and behavior. Symptoms eventually grow severe enough to interfere with daily tasks.
- Trial name
- NCT04496778
- Testing
- low level laser therapy ( laser acupuncture combined with nasal laser irradiation), aerobic exercise
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Dementia, Alzheimer Disease
Effects of Remote-based Resistance Training on Cardiometabolic Risk Factors, Cognitive Function, and Quality of Life in Adults Living With Alzheimer's Disease and/or Related Dementias
The investigators aim to study the effects of a 24-week remote-based resistance exercise training program on cardiovascular disease risk factors, cognitive function, and quality of life in older adults living with mild cognitive…
- Conditions
- Dementia, Alzheimer Disease, Dementia, Vascular, Lewy Body Disease
- Trial name
- NCT05004558
- Testing
- Remote-based Resistance Exercise Training
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Drexel University
Alzheimer Disease, Dementia
Jigsawdio Multisensory Platform for People With Mild Cognitive Impairment, Alzheimer's Disease, or Related Dementias
This study will evaluate Jigsawdio, a personalized multisensory jigsaw puzzle platform, for adults aged 60 years and older with mild cognitive impairment or mild dementia.
- Conditions
- Alzheimer Disease, Dementia, Mild Cognitive Impairment
- Trial name
- NCT07839286
- Testing
- Jigsawdio Multisensory Puzzle Platform, Standard Jigsaw Puzzle Activity
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Callahan-Young LLC DBA Jigsawdio
Psoriasis
A Study of the Impact of Apremilast (CC-10004) on Quality of Life, Efficacy, and Safety in Adults With Manifestations of Plaque Psoriasis and Impaired Quality of Life
The primary objective of the study is to assess the impact of treatment with apremilast 30 mg twice daily for 16 weeks, compared to placebo, on health-related quality of life (QOL) in adults with manifestations of plaque…
- Trial name
- EMBRACE (NCT03774875)
- Testing
- Apremilast
- Where
- 72 sites in France, Germany and 4 more
- Volunteers
- 277 people
- Sponsor
- Amgen
Older Adults, Hearing Impairment
Effect of an Aural Rehabilitation Program in Hearing-impaired Older Adults
Hearing impairment in older adults is becoming a common health problem as the population ages. The impact of hearing impairment in older adults includes not only physical function and cognitive performance, but also depression…
- Conditions
- Older Adults, Hearing Impairment, Nursing
- Trial name
- NCT05083221
- Testing
- Hear-Talk-Activity audiological program
- Where
- Taiwan
- Volunteers
- 96 people
- Sponsor
- National Taiwan University Hospital
Cognitive Impairment
Virtual Reality-Assisted Reminiscence Therapy in Older Adults With Cognitive Impairment
This study evaluated whether immersive virtual reality (VR) could enhance the effects of reminiscence therapy in older adults with cognitive impairment attending day-care services.
- Trial name
- NCT07825909
- Testing
- Virtual Reality-Assisted Reminiscence Therapy, Traditional Reminiscence Therapy
- Where
- 2 sites in Italy
- Volunteers
- 60 people
- Sponsor
- Istituto Universitario Salesiano Venezia-Mestre (IUS)
Dementia, Neurocognitive Disorders
Effectiveness and Cost-Effectiveness of Cognitive Stimulation Therapy - Spain (CST-ES) in People Living With Dementia
This study aims to evaluate the effectiveness and cost-effectiveness of CST-ES, the Spanish adaptation of Cognitive Stimulation Therapy (CST), to improve cognition and quality of life in people with mild to moderate dementia.
- Conditions
- Dementia, Neurocognitive Disorders, Mild Cognitive Impairment
- Trial name
- NCT06372002
- Testing
- Cognitive Stimulation Therapy (CST)
- Where
- 46 sites in Spain
- Volunteers
- 683 people
- Sponsor
- Instituto de Mayores y Servicios Sociales (IMSERSO)
Periodontal Diseases, Oral Halitosis
The Effect of Regular Home Use of Dual-light Antibacterial Photodynamic Therapy (aPDT) or the Use of a Powered Toothbrush in Older Individuals With Periodontitis and Mild Cognitive Impairment.
Objective: To compare three different oral hygiene regimens regarding plaque index (PI), bleeding on probing (BOP), the number of deepened periodontal pockets ≥4 mm (PPD), oral halitosis, and changes in oral health-related…
- Trial name
- e-DENT II (NCT07166224)
- Testing
- Oral-B Powered toothbrush, Dual-Light aPDT Treatment - Lumoral
- Where
- 2 sites in Sweden
- Volunteers
- 90 people
- Sponsor
- Blekinge Institute of Technology
Glioma
Application of Cognitive Training Based on the Remind Strategy in Glioma Patients With Cognitive Impairment
The purpose of this study is to form an interdisciplinary team to dynamically evaluate patient cognitive outcomes and develop an individualized cognitive training program for Chinese brain tumor patients
- Trial name
- NCT06327048
- Testing
- Individual cognitive rehabilitation training based on Remind strategy was given
- Where
- China
- Volunteers
- 69 people
- Sponsor
- YuanYuan Ma
Depression, Heart Failure
Combined Illness Management and Psychotherapy in Treating Depressed Elders
The purpose of this research study is to test a program developed to help patients with chronic heart or lung problems take care of themselves and cope with their illness or limitations.
- Conditions
- Depression, Heart Failure, Chronic Obstructive Pulmonary Disease
- Trial name
- COPE (NCT01337726)
- Testing
- Combined Psychotherapy and Illness Management, Illness Management Only
- Where
- 2 sites in United States
- Volunteers
- 226 people
- Sponsor
- University of Iowa
Mild Cognitive Impairment
Maintaining Independence and Quality of Life in Aging Adults Through Targeted Cognitive Training
Mild Cognitive Impairment, Alzheimer's Disease and Parkinson's Disease all represent a range of degenerative conditions that have cognitive impairments which all limit the ability for older individuals to self-manage care…
- Trial name
- NCT04539132
- Testing
- ABI Wellness Program
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kwantlen Polytechnic University
Stroke
Robot Mediated Therapy-Feasibility Study and Preliminary Effects
The goal of this clinical trial is to investigate the feasibility of the application of robot mediated impairment-training (RMIT) and robot mediated task-specific training (RMTT) in acute stroke patients with upper limb…
- Trial name
- NCT05729633
- Testing
- Robot mediated upper limb therapy
- Volunteers
- 4 people
- Sponsor
- Changi General Hospital
Mild Cognitive Impairment
The Feasibility and Effect of Digital Cognitive Training in Mild Cognitive Impairment
The goal of this study is to assess the feasibility and effect of digital cognitive training based on the principles of Differential Outcome Training (DOT) in patients with Mild Cognitive Impairment.
- Trial name
- NCT06399978
- Testing
- Brain Blossom - Gamified Differential Outcome Training, Gamified Non-Differential Outcome Training
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Pernille Louise Kjeldsen