Clinical trials: Quantitative Computed Tomography
Cystic Fibrosis
Skeletal Health and Bone Marrow Composition in Adolescents With Cystic Fibrosis
The investigators will be evaluating bone marrow composition via magnetic resonance imaging in adolescents diagnosed with cystic fibrosis (CF) compared to healthy, matched controls.
- Trial name
- NCT06216704
- Testing
- Magnetic resonance relaxometry, Magnetic resonance spectroscopy, Blood Draw
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Arthritis, Rheumatoid
Progression of Bone Erosions in Rheumatoid Arthritis Assessed by HR-pQCT and Conventional X-ray
Today, regular X-ray examination is not sufficiently sensitive for detecting progression of bone destruction in rheumatoid arthritis, but a new type of high-resolution CT scanner, the High-Resolution peripheral Quantitative…
- Trial name
- RACTX (NCT03429426)
- Where
- Denmark
- Volunteers
- 625 people
- Sponsor
- Aarhus University Hospital
Age-Related Osteoporosis
Dose-dependent Effects of Vitamin D on Bone Health
We propose to conduct a randomized double blind trial of three doses of vitamin D, 400, 4000, and 10,000 International Units (IU) per day, to assess the effect on bone density and architecture as assessed by high resolution…
- Trial name
- NCT01900860
- Testing
- Vitamin D
- Where
- Canada
- Volunteers
- 311 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Alpha-1 Antitrypsin Deficiency
The Use of High Resolution Chest Computed Tomography in Alpha-1 Antitrypsin Deficiency
Individuals with a deficiency of alpha-1 antitrypsin (AAT) often develop emphysema. Traditional lung function tests may not be the most accurate way to measure the progression of emphysema.
- Trial name
- QUANTUM-1 (NCT00532805)
- Where
- 7 sites in United States
- Volunteers
- 49 people
- Sponsor
- Medical University of South Carolina
Inspiration Expiration Thoracic TDM Sequences of Patients With Diffuse Interstitial Lung Disease (DIP)
Digital Modeling of Thoracic CT and Pulmonary Fibrosis
Currently, to our knowledge, there is little data on the combination of tools based on a similar concept to understand and evaluate ILDs.
- Trial name
- MLQ-CT (NCT06618924)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Coronary Artery Disease
Quantitative Analysis of Functional CT Imaging of Coronary Atherosclerosis
The purpose of this prospective observational study is to evaluate the diagnostic and prognostic performance of a "one-stop" comprehensive coronary artery anatomy and function assessment for CAD.
- Trial name
- NCT04986410
- Testing
- CCTA, CT-MPI, CT-FFR, SPECT-MPI
- Where
- China
- Volunteers
- 640 people, healthy volunteers welcome
- Sponsor
- Qilu Hospital of Shandong University
Chronic Obstructive Pulmonary Disease
Analysis With Clusters of QUAntitative Tomodensitometric Vascular, bronchIal and Parenchymal Pulmonary Parameters for COPD Patients
Chronic obstructive pulmonary disease (COPD) is caused by tobacco consumption. The goal is to characterize on clinical and radiological data, using computed tomography, this illness in order to improve diagnostic and be able to…
- Trial name
- ACQUAVIP (NCT03337854)
- Where
- France
- Volunteers
- 270 people
- Sponsor
- University Hospital, Bordeaux
Lung Inflammation, Sarcoidosis
Validation of the Analysis Methodology Behind the Use of Quantitative 18F-FDG PET/CT to Assess Lung Inflammation
The purpose of this study is to validate the method of analysing Positron Emission Tomography (PET) images to assess lung inflammation.
- Trial name
- VERIFY (NCT03312712)
- Testing
- PET/CT scan, LPS Challenge, Saline Challenge
- Where
- 2 sites in United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Osteoporosis, Bone Loss
Bone Microarchitectural Database Constitution From HR-pQCT Device in Clinical Situation Potentially Associated With Bone Loss
Bone fracture occurrence is associated with an increasing of morbidity and mortality. Some factors of fracture occurrence have been highlighted.
- Trial name
- DMPOs (NCT02532439)
- Testing
- HR-pQCT, DEXA, pQCT
- Where
- France
- Volunteers
- 287 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Coronary Artery Disease, Atherosclerosis
Measuring Athlete's Risk of Cardiovascular Events 3 (MARC-3)
Regular endurance exercise is widely known to improve cardiovascular health and reduce the risk of heart disease. Yet several imaging studies have shown that male endurance athletes have a higher prevalence of coronary artery…
- Trial name
- MARC-3 (NCT07625488)
- Where
- 2 sites in Netherlands
- Volunteers
- 250 people
- Sponsor
- Radboud University Medical Center
Traumatic Brain Injury
Single Photon Emission Computed Tomography (SPECT) Imaging Study of Professional American Football Players
The investigators primary objective is to acquire preliminary data on one-hundred former NFL veterans with at least one full year of professional service using brain SPECT imaging in order to assess the degree to which NFL…
- Trial name
- NCT01515839
- Testing
- Multivitamin Supplement intervention
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Amen Clinics, Inc.
Hypo or Hyperthyroidism
Thyroid Uptake Quantification Validation on a Three-dimensional (3D) Cadmium-Zinc-Telluride (CZT) New Generation Gamma Camera
Thyroid scintigraphy using technetium-99m (99mTc) pertechnetate is traditionally performed using planar imaging to estimate thyroid uptake.
- Trial name
- QThy2Dvc3D (NCT07610460)
- Testing
- No Intervention: Observational Cohort
- Where
- Monaco
- Volunteers
- 27 people
- Sponsor
- Centre Hospitalier Princesse Grace
Dental Diseases
Dual Energy Cone-Beam Computed Tomography (DE-CBCT) Assessment of Jaw Bone Density
Current radiologic imaging modalities used in dentistry provide information on the morphology of the hard tissues. Additional information on the density of bone has practical relevance, for example, in dental implant treatment…
- Trial name
- NCT04686084
- Testing
- Dual-energy computed tomography scan
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of California, Los Angeles