Clinical trials: Quitting Smoking
Smoking &Amp; Tobacco Cessation
An Innovative Conversational Agent (Quitbot) for Smoking Cessation
This phase III trial compares two remote digital smoking cessation programs to see how well they work for quitting smoking.
- Trial name
- NCT04308759
- Testing
- Experimental Smoking Cessation Program, Control Smoking Cessation Program
- Where
- United States
- Volunteers
- 1,647 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Smoking Cessation
Cigarette Pack Inserts for Smoking Cessation
This study will test whether cigarette package inserts (i.e., small printed leaflets inside cigarette packs) with messages about the benefits of cessation and tips for quitting can help smokers quit.
- Trial name
- NCT04075682
- Testing
- Inserts with efficacy messages, Pictorial warnings on packs
- Where
- 2 sites in United States
- Volunteers
- 387 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Tobacco Use Disorder
Persistence-Targeted Smoking Cessation
The investigators propose to develop a theory-based smoking cessation intervention (called Persistence-targeted smoking cessation; PTSC).
- Trial name
- PTSC (NCT01654107)
- Testing
- Persistence Targeted Smoking Cessation, Clearing The Air, Nicotine lozenge
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Tobacco Use Disorder
Evaluation of Oral Tobacco as a Harm Reduction Method for Smokers
Recently, tobacco companies have developed new oral tobacco products that are purportedly less harmful than conventional tobacco products.
- Trial name
- NCT00711100
- Testing
- Camel Snus, Marlboro Snus, Stonewall
- Where
- 2 sites in United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Smoking Cessation
Automated Mobile Contingency Management for Smoking Cessation: A Pilot RCT (SCC PREVAILgo)
The purpose of the proposed project is to pilot test an automated mobile phone-based contingency management (CM) approach to tobacco (smoking) cessation.
- Trial name
- NCT03739437
- Testing
- Mobile Contingency Management, Standard Care
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Smoking Cessation
Smartband Mindfulness Study
To determine treatment fidelity for a smartband/smartphone-based smoking monitoring, notification and brief mindfulness intervention.
- Trial name
- NCT03995225
- Testing
- Smartband automatic smoking detection combined with brief mindfulness interventions
- Where
- United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Yale University
Smoking Cessation
Informing Tobacco Treatment Guidelines for African American Non-Daily Smokers
The researchers are testing if counseling alone or counseling plus over-the-counter nicotine replacement therapies (NRT), like the patch,gum, or lozenge, helps African American non-daily smokers quit smoking.
- Trial name
- NCT02244918
- Testing
- Nicotine Replacement Therapy, Smoking Cessation Counseling
- Where
- 2 sites in United States
- Volunteers
- 278 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Smoking Cessation
PATH Partnering to Achieve Tobacco-free Health
The overall aim of this 5-year project is to capitalize on the strong theoretical and promising empirical evidence for Acceptance \& Commitment Therapy (ACT) as an intervention for smoking cessation by comparing the effectiveness…
- Trial name
- PATH (NCT01533974)
- Testing
- Acceptance & Commitment Therapy (ACT), Cognitive Behavioral Therapy (CBT)
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Insomnia, Nicotine Dependence
Study of Lunesta Versus Placebo for Sleep Problems Related to Smoking Cessation and Zyban
Objectives: The primary objective of this study is to determine the efficacy of eszopiclone at treating sleep problems related to withdrawal from nicotine in healthy smokers attempting smoking cessation.
- Trial name
- NCT00511134
- Testing
- Eszopiclone, Bupropion
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Yale University
Smoking Cessation, Second Hand Tobacco Smoke
Smoke-free Home Intervention in Permanent Supportive Housing
The focus of this study is on expanding access to voluntary smoke-free homes to formerly homeless residents residing in permanent supportive housing and examining the impact of this intervention on reducing tobacco-caused…
- Trial name
- NCT04855357
- Testing
- Resident counselling, Staff Training
- Where
- United States
- Volunteers
- 452 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Smoking Cessation
Partnering With Food Bank to Provide Tobacco Treatment to Underserved Smokers
This study evaluates the efficacy and economic impact of a theoretically-based, fully automated, interactive smartphone-based smoking cessation intervention.
- Trial name
- NCT05004662
- Testing
- Smartphone-delivered automated treatment, Nicotine patch, Counseling
- Where
- United States
- Volunteers
- 502 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Smoking Cessation
Nicotine Lozenge Bioequivalence Study
To compare the bio equivalence of new nicotine lozenge formulation with the reference nicotine lozenge so as to deliver the same nicotine blood profile.
- Trial name
- NCT01536704
- Testing
- Nicotine (2 mg), Nicotine (4 mg)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Smoking
Twitter-enabled Mobile Messaging for Smoking Relapse Prevention
We conducted a two-arm (test vs. control, N=160) randomized controlled trial of small, private, online support groups for quitting smoking with 20 people per group who were seeking to quit smoking.
- Trial name
- NCT01602536
- Testing
- smoking cessation aides, Twitter
- Where
- 2 sites in United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Smoking Cessation
Treatment of Smoking Lapses and Relapses
Many smokers who try to stop smoking with nicotine medications (NM) such as gum, lozenge and patch, go back to smoking (i.e., a slip or lapse).
- Trial name
- NCT01807871
- Testing
- nicotine patch, experimental use, nicotine patch, labeled use
- Where
- United States
- Volunteers
- 701 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Smoking Cessation
An Alternative Dosing Schedule of Varenicline for Smoking Cessation
The purpose of this study is to explore the use of an prolonged alternative dosing schedule using varenicline for smoking cessation leading to greater quit rates and higher rates of continuous abstinence.
- Trial name
- NCT00835900
- Testing
- varenicline
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Smoking Cessation
Advancing Tobacco Use Treatment for African American Smokers
The purpose of this study is to examine whether or not providing Chantix (varenicline) will help African American smokers quit smoking.
- Trial name
- KIS-IV (NCT02360631)
- Testing
- Chantix
- Where
- 2 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Lisa Sanderson Cox, PhD
Nicotine Dependence, Cigarettes
Penn State TXT2Quit Study
This study is evaluating the feasibility and short term smoking cessation outcomes of an automated smoking cessation intervention delivered via mobile phone text messaging as an adjunct to Varenicline in a primary care setting.
- Trial name
- NCT02367391
- Testing
- Motivational Text Messages, Control
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Smoking, Cigar
Cigarillo Warnings Image Sorting Study
The goal of this study is to examine the impact of repeated exposure to cigarillo warnings on cigarillo users' intentions and behaviors for cigarillo smoking.
- Trial name
- NCT05838378
- Testing
- Package image sorting with pictorial warnings, Package image sorting with Surgeon General text-only warnings, Package image sorting with FDA text-only warnings
- Where
- United States
- Volunteers
- 764 people, healthy volunteers welcome
- Sponsor
- Boston University
Smoking Cessation, HIV
TMS for Smoking Cessation in PLWHA Cessation in People Living With HIV/AIDS (PLWHA)
The pilot study proposal aims to modulate craving and attentional bias towards smoking cues in 40 people living with HIV/AIDS (PLWHA) using transcranial magnetic stimulation (TMS), with functional MRI (fMRI) brain correlates.
- Conditions
- Smoking Cessation, HIV, Craving
- Trial name
- NCT04936594
- Testing
- iTBS, TMS
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Gopalkumar Rakesh
Smoking Cessation
Pharmacokinetic Study of 4 mg Nicotine Lozenge.
This is a randomized, single center, open label, single dose, four way crossover study in fasted healthy male subjects to compare the pharmacokinetics of nicotine following administration of 3 prototype 4mg nicotine lozenge to an…
- Trial name
- NCT01669122
- Testing
- nicotine
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline