Clinical trials: Quitting Smoking
Smoking Cessation
Nicotine Lozenge Bioequivalence Study
To compare the bio equivalence of new nicotine lozenge formulation with the reference nicotine lozenge so as to deliver the same nicotine blood profile.
- Trial name
- NCT01536704
- Testing
- Nicotine (2 mg), Nicotine (4 mg)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Tobacco Cessation
Pilot Testing a Digital Intervention to Improve Smoking Cessation in Persons With Serious Mental Illness
All patients with serious mental illness are abstinent while in the hospital for a psychiatric admission yet almost all return to smoking after discharge.
- Trial name
- NCT04367506
- Testing
- BecomeAnEX, Usual Care
- Where
- 2 sites in United States
- Volunteers
- 59 people
- Sponsor
- University of Maryland, Baltimore
Smoking Cessation
Smoking Cessation for American Indians
American Indians and Alaska Natives (AI/ANs) have the highest smoking rates of the major racial/ethnic groups in the United States, approaching 40% to 50%.1-3 In addition, this underserved population has very low smoking…
- Trial name
- NCT01106456
- Testing
- All Nations Breath of Life (ANBL), Nontailored program (NT), Pharmacotherapy
- Where
- 2 sites in United States
- Volunteers
- 463 people, healthy volunteers welcome
- Sponsor
- Won Choi, PhD, MPH
Tobacco Dependence, Smoking Cessation
Use of Varenicline for 4-weeks Prior to Quitting
Varenicline (Champix) is a relatively new medicine that is effective in helping people to quit smoking. It is normally started 1-week before stopping smoking and used for up to 12-24 weeks.
- Trial name
- NCT00789074
- Testing
- Varenicline
- Where
- United Kingdom
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Tobacco Smoking
Heart Rate Variability Biofeedback for Smoking Cessation Treatment
The purpose of the study is to conduct an open trial examining the feasibility and acceptability of an adapted heart rate variability biofeedback and smoking cessation treatment that was using a primarily virtual remote…
- Trial name
- HRVB-SCT (NCT05224050)
- Testing
- Cognitive-Behavioral Smoking Cessation, Heart Rate Variability Biofeedback, Nicotine patch
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Smoking
Promoting Tobacco Control and Smoking Cessation in Workplaces [Phase I]
Previous research shows a significant proportion of smokers work in full-time employment. Given that the majority of smokers do not aware of the smoking cessation services available in Hong Kong, implementing smoking cessation…
- Trial name
- NCT02179424
- Testing
- Workshop, Face-to-face counseling, Phone counseling
- Where
- China
- Volunteers
- 642 people
- Sponsor
- The University of Hong Kong
Any Cancer Type
Mindfulness-Based Ecological Momentary Intervention For Smoking Cessation Among Cancer Survivors
The purpose of the study is to obtain feedback on a new quit-smoking treatment among individuals with a cancer diagnosis using a prototype app we developed.
- Trial name
- NCT06476548
- Testing
- EMI
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Smoking Cessation
Improving Adherence to Web-Based Cessation Programs: A Social Network Approach
This study will compare the efficacy of an interactive, evidence-based smoking cessation website (WEB) alone and in conjunction with 1) a theory-driven, empirically-informed social network (SN) protocol designed to integrate…
- Trial name
- NCT01544153
- Testing
- WEB, Social Network, Nicotine Replacement Therapy (NRT)
- Where
- United States
- Volunteers
- 5,292 people
- Sponsor
- Truth Initiative
Smoking
Trial of An Innovative Smartphone Intervention for Smoking Cessation
The goal of this study is to determine whether the novel smartphone app (SmartQuit) provides higher quit rates than the current standard smoking cessation app.
- Trial name
- NCT02724462
- Testing
- Smartphone-delivered Intervention (SmartQuit), : Smartphone-delivered Intervention (Standard of care app)
- Where
- United States
- Volunteers
- 2,503 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Smoking, Cessation
Usability Study of a Smoking Cessation Intervention During a Dental Cleaning
The goal of this usability study is to pilot test the recruitment procedures, data acquisition methods, and text message program integration required to support the planning of a future clinical trial.
- Trial name
- NCT04247061
- Testing
- Educational video, Text-message program
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Boston University
Cigarette Smoking
Controlled Study of the Ability of a Smokefree Tobacco Product to Increase the Quit Rate Among Cigarette Smokers
The study aims to assess if use of a low-nitrosamine, Swedish, smokefree tobacco product for oral use ("snus") can increase the quit rate among cigarette smokers who wish to stop smoking
- Trial name
- NCT00843622
- Testing
- Low-nitrosamine smokefree tobacco product for oral use
- Where
- 4 sites in United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Swedish Match AB
Smoking Cessation, Smoking, Tobacco
Pivot Breath Sensor Human Factors and Usability Study
Prospective, observational open label, single center study enrolling up to 15 subjects to evaluate human factors and usability of the Pivot Breath Sensor.
- Trial name
- NCT03835260
- Testing
- Pivot Breath Sensor
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Jennifer Marler, MD
Cessation, Smoking
Efficacy of a Smoke-Free Homes Intervention
The purpose of this study is to test whether the integration of a smoke-free homes intervention into the clinical guidelines for tobacco cessation can encourage sustained smoking cessation in low-income primary care patients.
- Trial name
- SFH 5A RCT (NCT04547686)
- Testing
- Smoke-Free Homes Intervention, Quitline
- Where
- United States
- Volunteers
- 916 people
- Sponsor
- Emory University
Smoking Cessation
A Study to Evaluate the Effect of Lorcaserin Hydrochloride on Smoking Cessation
In smokers who are motivated to stop smoking, treatment with lorcaserin compared with placebo will provide greater abstinence as measured by the last 4 weeks of treatment (Weeks 9-12). The target quit date was Day 15.
- Trial name
- NCT02044874
- Testing
- APD356-lorcaserin hydrochloride
- Where
- 31 sites in United States
- Volunteers
- 603 people
- Sponsor
- Arena Pharmaceuticals
Smoking Cessation, Nicotine Addiction
Circuitry-Guided Smoking Cessation in Schizophrenia
In a double-blinded, randomized, parallel controlled design, patients with schizophrenia spectrum disorder will be exposed to active or sham repetitive transcranial magentic stimulation (TMS) which was guided by functional…
- Conditions
- Smoking Cessation, Nicotine Addiction, Schizophrenia
- Trial name
- NCT03281629
- Testing
- Active TMS stimulation
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Maryland, Baltimore
Nicotine Dependence
An Effectiveness Trial of Maintenance Therapy for Nicotine Dependence
The transdermal nicotine patch is the most widely used form of tobacco dependence treatment in the US and Europe, but most smokers are unable to successfully quit with this form of treatment.
- Trial name
- NCT01047527
- Testing
- Transdermal nicotine patch
- Where
- 2 sites in United States
- Volunteers
- 525 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Smoking Cessation, Overweight
Internet-Administered Smoking Cessation Treatment for Overweight and Obese Smokers
This project will be a randomized clinical trial testing the efficacy of an internet-administered smoking cessation treatment for overweight and obese smokers.
- Conditions
- Smoking Cessation, Overweight, Obesity
- Trial name
- NCT01259466
- Testing
- Nicotine patch
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Yale University
Oral Disease, Smoking
Promoting Oral Health Among Smokers Randomized Trial
The current study will test the effectiveness of a multi-modal behavioral intervention (the Oral Health 4 Life program) targeted to smokers who are ready to quit smoking and seeking services through tobacco quitlines.
- Trial name
- NCT02347124
- Testing
- Usual Care Control, Enhanced Intervention
- Where
- United States
- Volunteers
- 718 people
- Sponsor
- Kaiser Permanente
COPD
Imaging Regional Lung Defect Severity
The purpose of this study is to develop and evaluate the usefulness of magnetic resonance imaging (MRI) using inert perfluorinated gases mixed with oxygen for regional assessment of pulmonary function.
- Trial name
- DIAL1001004 (NCT01640288)
- Testing
- Perfluorinated Gas/Oxygen Mixture, High Resolution CT of the Chest
- Where
- United States
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Hal C Charles
Smoking Cessation
Tobacco Treatment in the Context of Lung Cancer Screening
The proposed study will test a medication plus text messaging intervention specifically designed for lung cancer screening patients.
- Trial name
- NCT03927989
- Testing
- Text messaging plus nicotine replacement therapy, Standard Care at Lung Cancer Screening
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina