Clinical trials: Quitting Smoking
Smoking, Smoking Cessation
STARS (Smoking Treatment And Remote Sampling) Study
This is a research study to find out if a smoking cessation medications, either varenicline or nicotine replacement products (patches or lozenges), are effective when given to smokers, remotely, as a one-time sample.
- Conditions
- Smoking, Smoking Cessation, Tobacco Smoking, Cigarette Smoking
- Trial name
- NCT04525755
- Testing
- Varenicline 0.5 MG, Nicotine Replacement Therapy (NRT)
- Where
- United States
- Volunteers
- 652 people
- Sponsor
- Medical University of South Carolina
Nicotine Dependence
Adjunctive Mood Management for Telephone-based Smoking Cessation
Smoking is the leading cause of morbidity and mortality in the U.S. Interventions that increase successful quit attempts among depressed smokers with chronic medical illnesses are particularly important for the VA healthcare…
- Trial name
- NCT02500589
- Testing
- Behavioral mood management, Health education
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- VA Office of Research and Development
Tobacco Use Disorder
Novel Medication as a Potential Smoking Cessation Aid
The purpose of this study is to provide preliminary information assessing if levomilnacipran may be effective at increasing smoking cessation rates.
- Trial name
- NCT02265367
- Testing
- Levomilnacipran
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- University of Minnesota
Smoking Cessation
An Alternative Dosing Schedule of Varenicline for Smoking Cessation
The purpose of this study is to explore the use of an prolonged alternative dosing schedule using varenicline for smoking cessation leading to greater quit rates and higher rates of continuous abstinence.
- Trial name
- NCT00835900
- Testing
- varenicline
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Nicotine Dependence
Adaptive Pharmacotherapy for Smoking Cessation
The purpose of this study is to assess an "adaptive" approach to smoking cessation pharmacotherapy. The protocol is designed to compare adaptive vs.
- Trial name
- NCT02501265
- Testing
- Varenicline Standard Protocol, Nicotine Patch Standard Protocol, Varenicline Adaptive Protocol
- Where
- United States
- Volunteers
- 188 people
- Sponsor
- Duke University
Smoking Cessation
An EPIC Based BPA to Enhance Quit Line Referral and Use
Smoking is the number one cause of preventable death in the United States. Given the magnitude of the problem, interventions aimed at promoting smoking cessation have the potential to make large changes in improving health…
- Trial name
- NCT03229356
- Testing
- Best Practices Advisory (BPA), BPA + Enhanced Education
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Smoking Cessation
Nicotine Mouth Film for Craving Relief.
Nicotine mouth film is a new dosage form of nicotine replacement therapy. The purpose of this study is to investigate the craving relief efficacy of nicotine mouth film by comparing mint nicotine mouth film to nicotine lozenge in…
- Trial name
- NCT01702532
- Testing
- Nicotine
- Where
- 2 sites in United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Smoking Cessation
Twitter-enabled Mobile Messaging for Smoking Relapse Prevention (Tweet2Quit)
Tweet2Quit is an innovative smoking cessation intervention that combines real-time online peer-to-peer support with auto messaging.
- Trial name
- Tweet2Quit (NCT02823028)
- Testing
- NRT, Web Guide, Tweet2Quit
- Where
- 2 sites in United States
- Volunteers
- 980 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Tobacco Use, Tobacco Smoking
Persistence Targeted Smoking Cessation in Serious Mental Illness (SMI)
Due to the pandemic, this study was modified from a randomized clinical trial to test the feasibility, initial efficacy, and mechanisms of action of our PTSC-S intervention to a feasibility and acceptability test of our…
- Conditions
- Tobacco Use, Tobacco Smoking, Tobacco Use Cessation, Tobacco Use Disorder
- Trial name
- PTSC-S (NCT03873337)
- Testing
- Persistence Targeted Smoking Cessation in SMI (PTSC-S), Nicotine patch
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Rutgers, The State University of New Jersey
Smoking Cessation
Comparison of Conservative and Aggressive Smoking Cessation Treatment Strategies in a Vascular Surgery Office Practice
The aim of this study is to prove that the use of Bupropion with counseling works better than counseling alone for patients to quit smoking.
- Trial name
- NCT01850589
- Testing
- Aggressive Therapy
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Smoking Cessation
Informing Tobacco Treatment Guidelines for African American Non-Daily Smokers
The researchers are testing if counseling alone or counseling plus over-the-counter nicotine replacement therapies (NRT), like the patch,gum, or lozenge, helps African American non-daily smokers quit smoking.
- Trial name
- NCT02244918
- Testing
- Nicotine Replacement Therapy, Smoking Cessation Counseling
- Where
- 2 sites in United States
- Volunteers
- 278 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Cigarette Smoking-Related Carcinoma
Website Smoking Cessation Intervention for the Promotion of Smoking Cessation in Low-Income Veterans
This phase I trial studies how well a new electronic (e)-health smoking cessation program (called Vet Flexiquit) works in promoting smoking cessation in low-income veterans who may or may not be ready to quit smoking.
- Trial name
- NCT04502524
- Testing
- Smoking Cessation Intervention (New website), Smoking Cessation Intervention (Standard of care website), Health Education
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Tobacco Use Disorder
Pilot Study of Nicotine Replacement for Smoking Cessation During Pregnancy
We plan to examine the feasibility, acceptability, preliminary quit rates, overall nicotine exposure and adverse effects of the nicotine inhaler for smoking cessation in pregnancy.
- Trial name
- NCT00888979
- Testing
- Nicotrol Inhaler
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Hartford Hospital
Cocaine Dependence, Methamphetamine Dependence
Smoking-Cessation and Stimulant Treatment (S-CAST)
The primary objective of this study is to evaluate the impact of substance-abuse treatment as usual plus smoking-cessation treatment (TAU+SCT), relative to substance-abuse treatment as usual (TAU), on drug-abuse outcomes.
- Conditions
- Cocaine Dependence, Methamphetamine Dependence, Nicotine Dependence
- Trial name
- S-CAST (NCT01077024)
- Testing
- Smoking-cessation treatment
- Where
- 12 sites in United States
- Volunteers
- 538 people
- Sponsor
- University of Cincinnati
Smoking Cessation, HIV
A Smoking Cessation Trial in HIV-infected Patients in South Africa
The purpose of this study is to conduct a randomized controlled trial (RCT) of intensive anti-smoking counseling plus nicotine replacement therapy versus intensive anti-smoking counseling alone among HIV-infected patients in…
- Trial name
- JHU (NCT01484340)
- Testing
- Nicotine, Intensive Counseling
- Where
- 3 sites in South Africa
- Volunteers
- 560 people
- Sponsor
- Johns Hopkins University
Smoking Cessation
SmokefreeSGM, A Text-based Smoking Cessation Intervention for Sexual and Gender Minority Groups
The purpose of this study is to pretest the design of a text-based smoking cessation program tailored to sexual minority individuals.
- Trial name
- NCT05029362
- Testing
- SmokefreeSGM
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- The University of Texas Health Science Center, Houston
Smoking Cessation
Use of Nicotine Replacement Therapy (NRT) Sample and Brief Smoking Cessation Advice for Recruiting Smokers
Background More than 60% of the daily smokers in Hong Kong have never tried and have no intention to quit smoking. About 30.8% of daily smokers attempted to quit but failed.
- Trial name
- NCT03717051
- Testing
- Nicotine replacement therapy (NRT) sampling, Medication counseling
- Where
- Hong Kong
- Volunteers
- 834 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Weight Change, Body, Smoking Cessation
Efficacy of Two Novel Behavioral Post-cessation Weight Gain Interventions
The study aims to randomize 400 participants to 1 of 3 arms: a) a weight stability intervention prior to smoking cessation (Group 1); b) a weight loss intervention prior to smoking cessation (Group 2); or c) a self-guided weight…
- Trial name
- NCT03156660
- Testing
- Weight gain prevention (Group 1), Weight loss intervention (Group 2), Self-guided intervention (Group 3)
- Where
- United States
- Volunteers
- 305 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Lung Cancer Screening, Smoking Cessation
Gain-framed Messages and NRT for Lung Cancer Screening Patients
This research is a randomized smoking cessation trial conducted within and specifically personalized for lung cancer screening patients presenting to a lung screening clinic.
- Trial name
- NCT03069924
- Testing
- Gain-framed messaging, Unframed messaging materials
- Where
- 2 sites in United States
- Volunteers
- 367 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Smoking Cessation, Electronic Cigarette Use
Cessation of Smoking Trial in the Emergency Department
The Cessation of Smoking Trial in the Emergency Department (CoSTED) is an National Institute for Health Research (NIHR) Health Technology Assessment (HTA) funded randomised controlled trial (RCT).
- Conditions
- Smoking Cessation, Electronic Cigarette Use, E-Cig Use, Vaping
- Trial name
- COSTED (NCT04854616)
- Testing
- CoSTED Intervention
- Where
- United Kingdom
- Volunteers
- 972 people, healthy volunteers welcome
- Sponsor
- Norfolk and Norwich University Hospitals NHS Foundation Trust