Clinical trials: Quitting Smoking
Smoking Cessation
Novel Smoking Cessation Drug for Schizophrenia
The investigators will evaluate effects of a novel drug that improves nicotinergic receptor function vs. placebo on short-term smoking abstinence in smokers with schizophrenia who have a high interest in quitting.
- Trial name
- TRENDS (NCT02230384)
- Testing
- Active JNJ Drug
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- K.N. Roy Chengappa
Smoking Cessation
Hospital-based Patient Navigation and Smoking Cessation
In a pilot randomized controlled trial (RCT), smokers hospitalized on the general internal medicine or family medicine service will be randomized to: 1) enhanced traditional care (ETC), or 2) patient navigation (PN).
- Trial name
- NCT03452371
- Testing
- Patient Navigation, Enhanced Traditional Care
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Boston Medical Center
Smoking Cessation
Personalized Smoking Cessation Tool Based on Patient Lung CT Image
Imbio is developing a Smoking Cessation Report (Report) that includes data analysis from a CT lung cancer screening exam. This randomized controlled (RCT) trial will clinically validate the Report's effectiveness at motivating…
- Trial name
- NCT03087617
- Testing
- Imbio Smoking Cessation Report, Smoking Cessation Counseling, Usual Care
- Where
- United States
- Volunteers
- 321 people
- Sponsor
- Imbio
Smoking Cessation
PATH Partnering to Achieve Tobacco-free Health
The overall aim of this 5-year project is to capitalize on the strong theoretical and promising empirical evidence for Acceptance \& Commitment Therapy (ACT) as an intervention for smoking cessation by comparing the effectiveness…
- Trial name
- PATH (NCT01533974)
- Testing
- Acceptance & Commitment Therapy (ACT), Cognitive Behavioral Therapy (CBT)
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Smoking Cessation
Testing the Integrated mHealth App Intervention "SiS-H"
The present study is a pilot randomized controlled trial (RCT) that seeks to test the feasibility, acceptability, process outcomes, and exploratory outcomes of a newly integrated, app-based smoking cessation treatment (SiS-H…
- Trial name
- NCT05886621
- Testing
- Smiling instead of Smoking - HIV, QuitGuide
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Massachusetts General Hospital
Smoking, Smoking Cessation
Improving the Population-Wide Effectiveness of U.S. Tobacco Cessation Quitlines
Research shows that smoking cessation is the most significant preventable health behavior change that a person can make to lower cancer risk.
- Trial name
- NCT01087905
- Testing
- Nicotine patch, Nicotine gum, CMAC
- Where
- 2 sites in United States
- Volunteers
- 987 people
- Sponsor
- University of Wisconsin, Madison
Cigarette Smoking
Smoking Cessation Intervention in Public Housing
The major aim of this study is to test the effectiveness of a bundled, multi-level intervention (Sister to Sister) on smoking cessation outcomes in female smokers residing in public housing neighborhoods.
- Trial name
- NCT01035151
- Testing
- Experimental, Control
- Where
- 2 sites in United States
- Volunteers
- 420 people
- Sponsor
- Medical University of South Carolina
Smoking Cessation, Smoking
A Quit Smoking Study Using Smartphones
The objective of this research is to determine whether smartphone games show promise for helping smokers increase their chances of quitting.
- Conditions
- Smoking Cessation, Smoking, Nicotine Dependence
- Trial name
- NCT02164383
- Testing
- Nicotine patch, Cessation Counseling, Mobile Games
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Wisconsin, Madison
Smoking Cessation
Informing Tobacco Treatment Guidelines for African American Non-Daily Smokers
The researchers are testing if counseling alone or counseling plus over-the-counter nicotine replacement therapies (NRT), like the patch,gum, or lozenge, helps African American non-daily smokers quit smoking.
- Trial name
- NCT02244918
- Testing
- Nicotine Replacement Therapy, Smoking Cessation Counseling
- Where
- 2 sites in United States
- Volunteers
- 278 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Smoking, Smoking Cessation
QuitFast: Evaluating Transcranial Magnetic Stimulation as a Tool to Reduce Smoking Directly Following a Quit Attempt
Cigarette smoking constitutes the greatest preventable cause of mortality and morbidity in the US. The most critical period for long term success of smoking cessation appears to be in the first 7 days after the quit date.
- Conditions
- Smoking, Smoking Cessation, Craving, Addiction
- Trial name
- NCT04159571
- Testing
- Real TBS to the vmPFC
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Wake Forest University Health Sciences
Tobacco Use Disorder, Smoking Cessation
Mechanisms of Lorcaserin for Smoking Cessation
Identifying new medication options is critical for curbing the health burdens of cigarette smoking. Currently approved smoking cessation medications act on nicotinic receptors, and additional work is needed to identify…
- Trial name
- NCT04396834
- Testing
- Lorcaserin Oral Tablet
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- The Mind Research Network
Smoking Cessation
Smoking Cessation Study In Healthy Adolescent Smokers
The study is designed to see if varenicline combined with age appropriate (adolescent) smoking cessation counseling will help teens quit smoking.
- Trial name
- NCT01312909
- Testing
- Varenicline 1mg BID, Varenicline 0.5mg BID
- Where
- 80 sites in United States, Canada and 4 more
- Volunteers
- 312 people
- Sponsor
- Pfizer
Cigarette Smoking
Financial Incentives for Smoking Cessation Among Mothers
Investigators will examine whether adding financial incentives and nicotine replacement dual therapy to current best practices for smoking cessation (i.e.
- Trial name
- NCT05740098
- Testing
- Best Practices, Financial Incentives, Nicotine Replacement Therapy
- Where
- United States
- Volunteers
- 198 people
- Sponsor
- University of Vermont
Nicotine Dependence, Cigarette Smoking
Smoking Cessation for Smokers With Sleep Problems
This is a pilot research study examining two types of behavioral counseling along with the nicotine patch for smoking cessation.
- Conditions
- Nicotine Dependence, Cigarette Smoking, Insomnia
- Trial name
- NCT01277887
- Testing
- Cognitive-Behavioral Counseling, Smoking Cessation Counseling
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Yale University
Endothelial Dysfunction
Impact of Smoking Cessation and γ-Tocopherol to Restore Vascular Endothelial Function
Cigarette smoking is a significant risk factor for cardiovascular disease (CVD) and is the leading cause of premature mortality in the US.
- Trial name
- NCT01314443
- Testing
- Nicotine Replacement Therapy (NRT), Gamma-Tocopherol, Smoking cessation
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Smoking Cessation
Supplemental Nicotine Administration for Smoking Cessation in Posttraumatic Stress Disorder (PTSD)
The investigators propose to evaluate the relationship between PTSD, mood, craving and withdrawal symptoms and factors associated with relapse in the context of a randomized clinical smoking cessation trial.
- Trial name
- NCT01055886
- Testing
- nicotine patch
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Duke University
Smoking Cessation
Varenicline Observational Investigation In The Cessation of Smoking
The purpose of this study is to determine the safety and efficacy of varenicline in the real-world environment of smokers attending primary care in routine clinical practice with the addition of being offered behavioral support…
- Trial name
- CHOICES (NCT00669240)
- Testing
- Varenicline
- Where
- 52 sites in Belgium, Greece and 2 more
- Volunteers
- 567 people
- Sponsor
- Pfizer
Smoking Cessation
Automated Mobile Contingency Management for Smoking Cessation: A Pilot RCT (SCC PREVAILgo)
The purpose of the proposed project is to pilot test an automated mobile phone-based contingency management (CM) approach to tobacco (smoking) cessation.
- Trial name
- NCT03739437
- Testing
- Mobile Contingency Management, Standard Care
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Tobacco Dependence, Smoking
Bupropion SR Plus Counseling for Smoking Cessation
The purpose of this study was to determine if bupropion plus counseling was more effective than bupropion alone or counseling alone in helping smokers quit smoking.
- Trial name
- NCT01621009
- Testing
- Active bupropion + counseling, Active bupropion, No counseling
- Where
- United States
- Volunteers
- 463 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Smoking Cessation
Smoking Cessation After Hospitalization for a Cardiopulmonary Illness
Smoking-related cardiopulmonary diseases account for a large number of hospital admissions. We investigated the efficacy of hypnotherapy as an aid to a counseling-based smoking cessation program in improving quit rates of…
- Trial name
- STOPP (NCT01791803)
- Testing
- hypnotherapy, Nicotine
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- North Shore Medical Center