Clinical trials: RANDOMIZED, open to volunteers
Urological Surgery, Photobiomodulation (PBM)
PBM Patch for Postoperative Pain Relief After Urological Surgery
This study is a prospective, randomized, double-blind, placebo-controlled clinical study designed to evaluate the efficacy and safety of a photobiomodulation (PBM) patch (Super Vi PBM Patch - Soothing) and an enhanced PBM patch…
- Conditions
- Urological Surgery, Photobiomodulation (PBM), Non-pharmacological Intervention, Double-blind Randomized Controlled Study
- Trial name
- NCT07671612
- Testing
- Super Vi PBM Patch - Soothing, Super Vi PBM Patch - Soothing EX
- Where
- 2 sites in Taiwan
- Volunteers
- 300 people
- Sponsor
- National Taiwan University Hospital
Liposome Bupivacaine, Erector Spinae Plane Block
The Effect of Liposomal Bupivacaine Erector Spinae Plane Block
This is a single-center, randomized, controlled, double-blind clinical trial. A total of 148 patients undergoing elective open upper abdominal surgery will be included and randomly assigned 1:1 to receive ultrasound-guided…
- Conditions
- Liposome Bupivacaine, Erector Spinae Plane Block, Postoperative Analgesia, Randomized Controlled Trial
- Trial name
- NCT07667439
- Testing
- Liposomal bupivacaine plus bupivacaine hydrochloride, Bupivacaine hydrochloride monotherapy
- Where
- China
- Volunteers
- 148 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Depressive Disorder (Per DSM-V Criteria, Mild-to-moderate), Acute Coronary Syndrome (ACS)
Efficacy of Transcutaneous Auricular Vagus Nerve Stimulation on Alleviating Major Depressive Disorder in Patients With Acute Coronary Syndrome After Percutaneous Coronary Intervention:A Prospective, Double-Blind,Randomized Controlled Study
This is a randomized, controlled study. ACS follow- up patients aged 18 to 80 years old with hemodynamic stability, who are 14 days to 1 year after PCI, are screened through the HAMD score and the HAMA score.
- Conditions
- Depressive Disorder (Per DSM-V Criteria, Mild-to-moderate), Acute Coronary Syndrome (ACS), Percutaneous Coronary Intervention (PCI), Depressive Disorder
- Trial name
- NCT07454070
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) Intervention
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Jing Han
This Study Will Develop Nurse Bridge and Test Its Six-month Effects on Nursing Students' Career Outcomes Using a Two-phase Randomized Controlled Trial
The Effectiveness of a Digital Career-Focused Mobile Application on Nursing Students' Career Planning and Career Trajectories .
Methods: This three-year experimental study is divided into two phases. In the first phase, a mixed-methods approach will be used.
- Trial name
- NurseBridge (NCT07628673)
- Testing
- Nurse Bridge App
- Where
- Taiwan
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
COPE, Breast Cancer
Creating Opportunities For Personal Empowerment (COPE) In Women With Breast Cancer During First-Line Therapy: A Pilot Randomized Controlled Trial
To learn if the Creating Opportunities for Personal Empowerment (COPE) intervention is feasible, acceptable, and helpful (compared to usual care) in women with breast cancer who are receiving first line treatment.
- Conditions
- COPE, Breast Cancer, First Line Therapy, Randomized Controlled Trial (RCT)
- Trial name
- NCT07610499
- Testing
- Standard of Care (SOC), Intervention sessions
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- M.D. Anderson Cancer Center
Postoperative Care, Rehabilitation
Multimodal AI-Guided Recovery Management After Lung Cancer Surgery
This study is a multicenter, prospective, randomized controlled trial designed to evaluate the effectiveness and safety of a multimodal artificial intelligence (AI)-guided postoperative recovery management system in patients…
- Conditions
- Postoperative Care, Rehabilitation, Artificial Intelligence (Al), Randomized Controlled Trial (RCT)
- Trial name
- AI-LungRecover (NCT07588737)
- Testing
- Conventional Internet-Based Rehabilitation Information, Large Language Model-Assisted Rehabilitation Nursing
- Where
- China
- Volunteers
- 868 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Forearm Injuries, Radius Fractures
Time to Healing in Displaced Pediatric Diaphyseal Forearm Fractures Treated With Bioabsorbable Compared to Titanium Intramedullary Nails
This study looks at children with forearm fractures that need surgery. The standard treatment uses titanium nails, which usually need to be removed in a second operation later.
- Conditions
- Forearm Injuries, Radius Fractures, Ulna Fractures, Fractures, Bone
- Trial name
- FOREST (NCT07536581)
- Testing
- Bioabsorbable intramedullary nail, Titanium elastic intramedullary nail
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Children's Fractures Interest Group, Denmark
Urinary Tract Infections, Recurrent
Electroacupuncture for the Prevention of Recurrent Lower Urinary Tract Infection in Women
The goal of this clinical trial is to evaluate if electroacupuncture works to prevent recurrent lower urinary tract infections in female patients. It will also learn about the safety of electroacupuncture.
- Conditions
- Urinary Tract Infections, Recurrent, Electroacupuncture, Randomized Controlled Trial (RCT)
- Trial name
- rLUTI (NCT07507851)
- Testing
- Electroacupuncture
- Where
- 2 sites in China
- Volunteers
- 312 people
- Sponsor
- Yanjun Zhang, Baoyan Liu
High Fidelity Simulation Training, Randomized Controlled Trials
Effect of Visual Deprivation of the Team Leader on Team Performance During Simulated Medical Emergencies
This multicenter randomized controlled study aims to evaluate the impact of temporary visual deprivation of the medical team leader on non-technical skills and team performance during high-fidelity simulated medical emergencies.
- Conditions
- High Fidelity Simulation Training, Randomized Controlled Trials, Education, Medical, Continuing, Education, Medical
- Trial name
- LEAD ME (NCT07427641)
- Testing
- Visual deprivation
- Where
- France
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Hyaluronan-EnRiched Medium, Randomized Controlled Trial
Effect of Hyaluronan-enriched Medium on the Cumulative Ongoing Pregnancy Rate.
Assessing whether the use of hyaluronan-enriched transfer medium can increase the cumulative ongoing pregnancy rate
- Trial name
- TETHER (NCT04697823)
- Testing
- use of hyaluronan-enriched transfer medium
- Where
- Belgium
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Rectal Cancer, Adenocarcinoma, Neoadjuvant Therapy
Neoadjuvant Chemoradiotherapy Plus Tislelizumab With or Without Probio-M9 in pMMR/MSS Locally Advanced Rectal Cancer
This prospective, single-center, randomized controlled trial aims to assessing the efficacy and safety of neoadjuvant chemoradiation plus Tislelizumab (PD-1 inhibitor) with or without Probio-M9 and subsequent TME surgery, by…
- Conditions
- Rectal Cancer, Adenocarcinoma, Neoadjuvant Therapy, Immunotherapy, Probio-M9
- Trial name
- NCRIT-PM9 (NCT07458529)
- Testing
- CRT+PD-1 inhibitor+Probio-M9
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Seventh Medical Center of PLA General Hospital
Elderly (People Aged 65 or More), LMA
Effects of Continuous Monitoring and Progressive Regulation of Inflatable Laryngeal Mask Airway Cuff Pressure on Postoperative Pharyngolaryngeal Complications in Elderly Patients
Currently, research on laryngeal mask airway (LMA) has been continuously deepened both domestically and internationally, which has greatly promoted the optimization process of clinical application and related management…
- Conditions
- Elderly (People Aged 65 or More), LMA, Randomized Controlled Trial, Laryngeal Mask Airways
- Trial name
- NCT07461467
- Testing
- Regulated and monitored ILMA, Empirically inflated LMA
- Where
- China
- Volunteers
- 146 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Problem-based Learning in Nursing Education, Nurses
Homogeneous vs. Heterogeneous Learning Style Grouping in Problem-Based Learning Among Nurses
Problem-based learning (PBL) is a learner-centered educational approach that helps nurses improve clinical skills through group discussion, case analysis, and collaborative problem-solving.
- Conditions
- Problem-based Learning in Nursing Education, Nurses, Randomized Clinical Trial
- Trial name
- NCT07435558
- Testing
- Homogeneous FSLSM-Based PBL Grouping, Heterogeneous FSLSM-Based PBL Grouping
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
DIGEST, Evidence Based Measurement
Dissemination and Implementation of DIGEST™ as an Evidence-based Measurement Tool for Dysphagia: A Randomized Implementation Trial
To improve swallowing outcomes in cancer through clinical implementation of the Dynamic Imaging Grade of Swallowing Toxicity (DIGEST™) as an evidence-based practice (EBP) tool to grade pharyngeal dysphagia (difficulty swallowing)…
- Conditions
- DIGEST, Evidence Based Measurement, Dysphagia, Randomized Implementation
- Trial name
- NCT07283653
- Testing
- No intervention, DIGEST Training Program, DIGEST Training + Practice Facilitation
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- M.D. Anderson Cancer Center
Lumbar Microdiscectomy, Postoperative Rehabilitation
Effectiveness of a Visual Feedback Exercise Program Following Lumbar Surgery
The aim of this study is to compare the effectiveness of stabilization exercises performed with visual feedback guided by a laser pointer after lumbar microdiscectomy surgery with that of standard stabilization exercises.
- Conditions
- Lumbar Microdiscectomy, Postoperative Rehabilitation, Randomized Controlled Trial
- Trial name
- NCT07382830
- Testing
- Exercise, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Suleyman Demirel University
Pediatric Urolithiasis, Extracorporeal Shock Wave Lithotripsy
Optical Motion Capture-Assisted Ultrasound for Pediatric ESWL
The incidence of pediatric urinary system stones has shown an upward trend in recent years, and Extracorporeal Shock Wave Lithotripsy (ESWL) has become one of the most important minimally invasive treatments for pediatric upper…
- Conditions
- Pediatric Urolithiasis, Extracorporeal Shock Wave Lithotripsy, Optical Motion Capture, Ultrasound Localization
- Trial name
- NCT07299032
- Testing
- ESWL with Optical Motion Capture-Assisted Ultrasound Localization, ESWL with Conventional Ultrasound Localization
- Where
- China
- Volunteers
- 80 people
- Sponsor
- The Children's Hospital of Zhejiang University School of Medicine
Endoscopy, Pain
Effect of Visualized Meditation on Anxiety, Pain, and Comfort in Patients Undergoing Endoscopy
Endoscopy is one of the most frequently performed procedures for the early diagnosis and treatment of many diseases and plays a crucial role in the diagnosis and treatment of upper gastrointestinal disorders.
- Conditions
- Endoscopy, Pain, Comfort, Randomized Controlled Trial
- Trial name
- NCT07261839
- Testing
- Visualized meditation
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- University of Gaziantep
Spinal Diseases, Endoscopy Simulation
Comparing 3D and 2D Views in Biportal Spine Surgery: A Pilot Simulation Study
This study aims to compare three-dimensional (3D) and two-dimensional (2D) visualization in biportal endoscopic spine surgery using a simulated environment.
- Conditions
- Spinal Diseases, Endoscopy Simulation, Lumbar Vertebrae, Randomized Controlled Trial
- Trial name
- NCT07171801
- Testing
- Three-Dimensional Endoscopic Visualization, Two-Dimensional Endoscopic Visualization
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Felix Corr
Kidney Transplantation Recipients, Sodium-Glucose Transporter 2 Inhibitors
SGLT2i Safety and Efficacy on Kidney Allograft Function in Non-diabetic Kidney Transplant Recipients
This clinical trial investigates whether 18 months of daily SGLT2i (10 mg Forxiga) preserves kidney function and evaluates safety, based on eGFR changes and adverse event occurrence in non-diabetic kidney transplant recipients.
- Conditions
- Kidney Transplantation Recipients, Sodium-Glucose Transporter 2 Inhibitors, Non-Diabetic Patients, Randomized Controlled Trial
- Trial name
- SGL-TX-GFR (NCT07143773)
- Testing
- SGLT-2 inhibitor
- Where
- Denmark
- Volunteers
- 88 people
- Sponsor
- Odense University Hospital
Intracranial Aneurysm, CT Angiography
Stepped-Wedge Cluster Randomized Trial of AI-Assisted CTA Detection for Intracranial Aneurysms in Regional Hospitals
This study (IDEAL 2) is a nationwide stepped-wedge cluster-randomized trial designed to prospectively enroll over 14,400 patients undergoing outpatient head CT angiography (CTA).
- Conditions
- Intracranial Aneurysm, CT Angiography, AI (Artificial Intelligence), Cluster Randomized Trial
- Trial name
- IDEAL2 (NCT07124624)
- Testing
- AI-Assisted CTA Interpretation, Standard CTA Interpretation
- Volunteers
- 14,400 people, healthy volunteers welcome
- Sponsor
- Jinling Hospital, China