Clinical trials: RANDOMIZED
Myofacial Pain Syndrome, Botulinum Toxin
Botulinum Toxin A in Patients With Myofascial Pain Syndrome With and Without Zinc Supplementation
Research question: Dose the use of oral zinc supplement improve the effects of botulinum toxins injection in patients with myofascial pain dysfunction syndrome? Statement of the problem: MPDS Patients treated with botulinum toxin…
- Trial name
- NCT05605886
- Testing
- Solvazinc 50mg
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pain, Acute
Comparison of Morphine With Nalbuphine in a Multimodal Approach for Pain Relief in Patients Undergoing Gynecological Procedures: Randomized Controlled Double Blind Clinical Trial
This study was conducted in the Aga Khan University Hospital, Karachi. Pakistan is developing country and overall shortage of Morphine in developing country.
- Trial name
- NCT06191770
- Testing
- Morphine,
- Where
- Pakistan
- Volunteers
- 66 people
- Sponsor
- Aga Khan University Hospital, Pakistan
Retroperitoneal Sarcoma
Neoadjuvant Short-course Hypofractionated PBT for Non-metastatic RPS
The investigators' study titled "PROTONS-RPS: a Phase II non-Randomized Open-label single-arm Trial Of Neoadjuvant Short-course hypofractionated proton beam therapy for non-metastatic RetroPeritoneal Sarcoma" is a phase II trial…
- Trial name
- PROTONS-RPS (NCT05302570)
- Testing
- Hypofractionated Proton Beam Therapy
- Where
- 2 sites in United States
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Exercise
High-Intensity Functional Training (HIFT) vs Moderate-Intensity Continuous Training (MICT) in College Students
The purpose of this study is to compare two types of exercise programs in college students: high-intensity functional training and moderate-intensity continuous training.
- Trial name
- NCT07745270
- Testing
- High-Intensity Functional Training (HIFT), Moderate-Intensity Continuous Training (MICT)
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Miami
Premenstrual Syndrome
The Effect of Mandala Art Therapy in Coping With Premenstrual Syndrome
Mandala practice will be applied to women with premenstrual syndrome. The intervention group (Mandala practice group) and the control group each consisted of 60 women.
- Trial name
- NCT06144073
- Testing
- Intervention (Mandala art therapy) group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Healthy Volunteers
To Demonstrate Equivalent Pharmacokinetic Properties of HD204 and Bevacizumab (Avastin®) in Healthy Male Subjects
The purpose of this study is to compare the pharmacokinetics, as well as to evaluate the safety, tolerability and immunogenicity of HD204, US-Avastin and EU-Avastin in healthy male subjects after intravenous administration of a…
- Trial name
- NCT03390673
- Testing
- HD204, Avastin
- Where
- 2 sites in New Zealand
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Prestige Biopharma Limited
Healthy
Pharmacokinetic Study of JNJ-42756493 in Healthy Participants
The purpose of this study is to evaluate the absolute bioavailability (the extent to which a drug or other substance becomes available to the body) of JNJ-42756493 following a single 10 milligram (mg) dose as an oral solution…
- Trial name
- NCT02218073
- Testing
- JNJ-42756493 10 mg tablet, JNJ-42756493 10 mg Oral Solution, JNJ-61818549
- Where
- Belgium
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Incisional Hernia of Anterior Abdominal Wall
Study on the Efficacy of Prophylactic on Lay Mesh in Preventing Post-operative Hernia in Liver Transplant Patients
Study Design: Single-blinded, randomized, prospective clinical trial. Study Population: End-stage liver disease patients' candidates for liver transplantation.
- Trial name
- NCT04512469
- Testing
- Low molecular weight mesh
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Chronic Subjective Tinnitus
Transcutaneous Auricular Vagus Nerve Stimulation Combined With Tailor-Made Notched Music Training Therapy for Chronic Subjective Tinnitus
This study is a prospective, multicenter, randomized, controlled, open-label clinical trial designed to evaluate the superiority of transauricular vagus nerve microcurrent stimulation (taVNS) combined with Tailor-Made Notched…
- Trial name
- NCT07469969
- Testing
- transcutaneous auricular vagus nerve stimulation combined with tailor-made notched music training therapy, tinnitus retraining therapy
- Where
- China
- Volunteers
- 386 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Small-cell Lung Cancer
Amrubicin Study for Elderly Patients With Extensive-disease Small-cell Lung Cancer (ED-SCLC)
The purpose of this study is to compare the efficacy and toxicity of amrubicin with carboplatin plus etoposide in elderly patients with extensive-disease small-cell lung cancer.
- Trial name
- NCT00286169
- Testing
- Amrubicin Hydrochloride
- Where
- 8 sites in Japan
- Volunteers
- 130 people
- Sponsor
- Sumitomo Pharma Co., Ltd.
Obesity, Morbid
Body Composition Optimization Intervention RCT
This study aims to identify if the addition of structured nutrition/weight loss counseling to patients at the bariatric clinic can increase the conversion from bariatric clinic to surgical candidacy from (the current) 11% to a…
- Trial name
- NCT05993169
- Testing
- Body Composition optimization visits
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Jacob M. Elkins
Primary Insomnia
Sleep Laboratory Study to Investigate the Safety and Efficacy of Neu-P11 in Primary Insomnia Patients
This is a phase II study. It is conducted using a randomized, double-blind, 3-arm placebo controlled, parallel group design. Eligible patients will be randomized in a 1:1:1 ratio to receive Neu-P11 20 mg, Neu-P11 50 mg or placebo…
- Trial name
- NCT01489969
- Testing
- Neu-P11
- Where
- 9 sites in United States
- Volunteers
- 137 people
- Sponsor
- Neurim Pharmaceuticals Ltd.
Bipolar Disorder, Attention Deficit Hyperactivity Disorder
Aripiprazole Associated With Methylphenidate in Children and Adolescents With Bipolar Disorder and ADHD
There is a scarcity of clinical trials assessing the effects of medications in children with bipolar disorder. This study aims to assess the efficacy of Aripiprazole associated with Methylphenidate (MPH)for the treatment of…
- Trial name
- NCT00305370
- Testing
- Aripiprazole
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Federal University of Rio Grande do Sul
Endometritis
Doxycycline Prophylaxis at Vacuum Aspiration Trial
This study is a randomized, double-blinded, controlled trial comparing two regimens of doxycycline for the prevention of infection after surgical abortion.
- Trial name
- Tu Du Doxy (NCT00547170)
- Testing
- Doxycycline pre-operatively, Doxycycline post-operatively
- Where
- Vietnam
- Volunteers
- 1,000 people
- Sponsor
- University of Pittsburgh
IPF
A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase III Study to Evaluate the Efficacy and Safety of HSK44459 Tablets in Patients With Idiopathic Pulmonary Fibrosis
This study aims to evaluate the efficacy and safety of HSK44459 tablets in patients with idiopathic pulmonary fibrosis (IPF).
- Trial name
- NCT07519070
- Testing
- HSK44459
- Volunteers
- 420 people
- Sponsor
- Haisco Pharmaceutical Group Co., Ltd.
Lung Cancer
Postoperative Rehabilitation in Operation for LUng CAncer (PROLUCA)
Purpose The purpose of the PROLUCA study is to investigate the efficacy of early postoperative rehabilitation in a non-hospital setting in patients with operable lung cancer, with focus on exercise training.
- Trial name
- PROLUCA (NCT02439073)
- Testing
- Rehabilitation
- Where
- Denmark
- Volunteers
- 235 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Friedreich Ataxia
Efficacy Study of Epoetin Alfa in Friedreich Ataxia
Friedreich's ataxia (FRDA) is a rare genetic disorder characterised by severe neurological disability and cardiomyopathy. Friedreich's ataxia is the consequence of frataxin deficiency.
- Trial name
- FRIEMAX (NCT01493973)
- Testing
- Epoetin alfa
- Where
- 3 sites in Italy
- Volunteers
- 56 people
- Sponsor
- Federico II University
Obesity, Lipid Disorders
A Clinical Study to Evaluate the Safety,Tolerability and PK of ZYT1, Following Oral Administration in Healthy Volunteers
This is a clinical study to evaluate the safety, tolerability and pharmacokinetics of ZYT1, following oral administrations in healthy volunteers. The study shall be divided into four plans as given below: 1.
- Trial name
- NCT01543269
- Testing
- ZYT1
- Where
- India
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Zydus Lifesciences Limited
Cancer Head Neck, Cancer, Head
Randomized Evaluation of Machine Learning Assisted Radiation Treatment Planning vs Standard Radiation Treatment Planning
The purpose of this study is to determine the magnitude of clinical benefit achieved through machine learning assisted radiation treatment planning (MLAP) on post-treatment clinical outcomes such as acute toxicity and patient…
- Conditions
- Cancer Head Neck, Cancer, Head, Cancer Neck
- Trial name
- NCT05979883
- Testing
- Machine Learning Assisted Radiation (MLAP) RapidPlan, Radiation Therapy Standard of Care (SOC)
- Where
- 6 sites in United States
- Volunteers
- 204 people
- Sponsor
- Mayo Clinic
Breast Cancer
Efficacy of Exercise Using Connected Activity Trackers and Therapeutic Education in Localized Breast Cancer
The 3-year DISCO study aims to systematically implement physical activity in breast cancer patients. The primary objective is to investigate the efficacy of a connected device (personalized non-supervised exercise program…
- Trial name
- DISCO (NCT03529383)
- Testing
- Connected device, Therapeutic education
- Where
- 3 sites in France
- Volunteers
- 436 people
- Sponsor
- Centre Leon Berard
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