Clinical trials: RANDOMIZED
IVF, Infertility
Is Adding E2 to P4 Luteal Support In High Responder Long Gn-RH Agonist ICSI Cycles Detrimental to Outcome? RCT
Study if supporting luteal phase of high responder (high egg production or high Estradiol level) long Gn_Rh agonist protocol ICSI/IVF cycle by combined Estradiol and progesterone impairs or improves outcome in terms of pregnancy…
- Trial name
- NCT01790282
- Testing
- estradiol plus progesterone 100 mg IM injection, Progesterone IM of 100 mg
- Where
- Egypt
- Volunteers
- 220 people
- Sponsor
- Mansoura Integrated Fertility Center
Peri-Implantitis
Peri-implantitis Surgical Regenerative Therapy Using Bovine Bone Substitute With Hyaluronic Acid
The study aimed to assess 6- and 12-months evaluation of clinical, microbiological, and radiography outcomes after performing peri-implantitis regenerative surgical therapy with the bovine bone substitute with or without…
- Trial name
- NCT05171582
- Testing
- Surgery 1 (Test group), Surgery 2 (Control group)
- Where
- Serbia
- Volunteers
- 25 people
- Sponsor
- Botiss Medical AG
Affect, Alcohol Consumption
Automated Telephone Follow-up in the Swedish Prison and Probation Services
The purpose of this study is to investigate whether automated telephony may be used for daily assessments of paroled offenders, and whether a brief intervention based on these daily assessments may result in a more positive…
- Conditions
- Affect, Alcohol Consumption, Substance Abuse
- Trial name
- NCT01727882
- Testing
- Brief feedback, Daily assessments
- Where
- Sweden
- Volunteers
- 108 people
- Sponsor
- Region Skane
Prostate Cancer
PR.7 Companion Trial: Effect of Intermittent Versus Continuous Androgen Suppression on Bone Loss and Body Composition
The purpose of this study is to determine, in patients entered on the National Cancer Institute of Canada (NCIC)-PR.7 trial of intermittent versus continuous androgen ablation, whether the rates of osteoporosis, fractures, and…
- Trial name
- NCT00228124
- Where
- Canada
- Volunteers
- 300 people
- Sponsor
- Ontario Cancer Research Network
Advanced Breast Cancer
A Study to Learn About a New Medicine Called Vepdegestrant (ARV-471, PF-07850327) in People Who Have Advanced Metastatic Breast Cancer
A study to learn about a new medicine called ARV-471 (PF-07850327) in people who have advanced metastatic breast cancer.
- Trial name
- VERITAC-2 (NCT05654623)
- Testing
- ARV-471, Fulvestrant
- Where
- 312 sites in United States, Argentina and 29 more
- Volunteers
- 624 people
- Sponsor
- Pfizer
Gut Microbiota
Effects of Riboflavin on Faecalibacterium Prausnitzii and the Gut Microbiota
The purpose of this trial is to investigate comprehensively the effect of riboflavin supplementation on the abundance of F. prausnitzii and on other members of the gut microbiota in faeces of healthy volunteers.
- Trial name
- NCT02929459
- Testing
- Riboflavin Dose 1, Riboflavin Dose 2
- Where
- Netherlands
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- dsm-firmenich Switzerland AG
Breast Cancer
Comparison of Two Regimens of Liposomal Doxorubicin in Treating Women With Metastatic Breast Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known which regimen of liposomal doxorubicin is more effective for metastatic breast cancer.
- Trial name
- NCT00005980
- Testing
- pegylated liposomal doxorubicin hydrochloride
- Where
- 14 sites in Austria, France and 7 more
- Volunteers
- 116 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Close Contacts of Active Tuberculosis
Efficacy of Nyaditum Resae(R) Against Active TB in Georgia
The use of a supplement food like "Nyaditum resae" is a reliable opportunity to stop the progression towards active TB through the most updated knowledge of this disease:the induction of tolerance.
- Trial name
- NCT02897180
- Testing
- Nyaditum resae(R)
- Where
- Georgia
- Volunteers
- 3,300 people, healthy volunteers welcome
- Sponsor
- Fundació Institut Germans Trias i Pujol
Major Depressive Disorder
Study to Evaluate Treatment Effects Associated With the NeuroStar SoftStart Treatment Feature
The purpose of this study is to evaluate the comfort of the NeuroStar® Advanced Therapy System regular prescribed TMS protocol versus a New Feature.
- Trial name
- Comfort Start (NCT05535062)
- Testing
- repetitive Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Neuronetics
General Medical Inpatient Conditions
IMPaCT (Individualized Management Towards Patient-Centered Targets)
The investigators propose a pilot randomized controlled trial of a care transitions intervention in which trained Community Health Workers will act as supports for socioeconomically vulnerable patients who are being discharged…
- Trial name
- PaCT (NCT01346462)
- Testing
- Patient-Centered Transition Intervention
- Where
- United States
- Volunteers
- 513 people
- Sponsor
- University of Pennsylvania
Pancreatic Cancer, GastroEsophageal Cancer
Supportive Oncology Care At Home RCT
This research study is evaluating a program that entails remote monitoring and home-based care for people with cancer who are receiving chemotherapy, radiotherapy, or chemoradiotherapy.
- Conditions
- Pancreatic Cancer, GastroEsophageal Cancer, Rectal Cancer, Head and Neck Cancer
- Trial name
- NCT04544046
- Testing
- Supportive Oncology Care at Home, Usual Care
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Massachusetts General Hospital
Smoking Cessation, Surgery--Complications
Smoking Cessation Prior to Gynecological Surgery
This study evaluates whether current smokers scheduled for gynecological surgery will stop smoking to a higher extent if they or the surgeon is exposed to information on smoking cessation prior to surgery in a web-based…
- Trial name
- NCT03942146
- Testing
- Information on smoking cessation
- Where
- Sweden
- Volunteers
- 1,609 people
- Sponsor
- Sahlgrenska University Hospital
Pregnancy, Pregnancy-Related Pain
Integrated Medical, Surgical and Physiotherapy Care for Pregnant Women With Chronic Diseases
This non-randomized controlled quasi-experimental study evaluates the effectiveness of an integrated medical-surgical and physiotherapy community-based care model for pregnant women with chronic diseases.
- Conditions
- Pregnancy, Pregnancy-Related Pain, Musculoskeletal Disorders, Physical Therapy
- Trial name
- IMSP-PregCD (NCT07589946)
- Testing
- Physiotherapy-based Care, control group
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Sinai University
Low-level Laser Acupuncture in Patients With Total Knee Arthroplasty
Low-level Laser Acupuncture Reduces Postoperative Pain and Morphine-related Side Effects in Patients With Total Knee Arthroplasty:
Total knee arthroplasty is a common and effective surgical procedure for patients with end-stage knee osteoarthritis, and wound pain is still a problem for many of the patients.
- Trial name
- NCT03995446
- Testing
- low-level laser
- Where
- Taiwan
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Insulin Checklist
The Effect of a Checklist on the Education of Simulated Patients During Insulin Initiation
The increasing prevalence of diabetes is associated with increased insulin use. In developing countries it is frequently necessary to use insulin, with the needle and syringe method of administration being the cheapest approach.
- Trial name
- NCT02266303
- Testing
- Insulin Start-up Checklist
- Where
- Barbados
- Volunteers
- 100 people
- Sponsor
- The University of The West Indies
Post Operative Pain
Ultrasound-guided Transversus Abdominis Plane Block After Hysterectomy
In this randomized, controlled, observer-blinded study we plan to evaluate ultrasound-guided transversus abdominis plane (TAP) block for postoperative pain management in patients undergoing abdominal hysterectomy.
- Trial name
- TAP (NCT01153503)
- Testing
- TAP block
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Autism Spectrum Disorder (ASD), Autism
Xenon Therapy for Children With Autism Spectrum Disorder
This study aims to evaluate the efficacy and safety of inhaled xenon for the treatment of children with autism spectrum disorder (ASD).
- Trial name
- ASD; Xe (NCT07435103)
- Testing
- Xenon
- Where
- China
- Volunteers
- 72 people
- Sponsor
- The Children's Hospital of Zhejiang University School of Medicine
Neurocysticercosis
Treatment of Peri-calcification Edema in Neurocysticercosis (NCC)
Three-arm open, randomized comparative study of acetazolamide, dexamethasone, or no additional treatment to evaluate decrease in peri-calcification edema in neurocysticercosis
- Trial name
- NCT02945527
- Testing
- Acetazolamide, Dexamethasone
- Where
- Peru
- Volunteers
- 4 people
- Sponsor
- Universidad Peruana Cayetano Heredia
Asthma
Effect of a Mobile App on Improving Asthma Control in Patients With Persistent Asthma
mINSPIRERS_RCT aims to assess the magnitude of the effect of a mobile app for improving asthma control in adolescents and adults with persistent asthma, followed at primary and secondary care in Portugal.
- Trial name
- mINSPIRERS_RCT (NCT05129527)
- Testing
- InspirerMundi app, Usual care
- Where
- Portugal
- Volunteers
- 124 people
- Sponsor
- Universidade do Porto
Hepatocellular Carcinoma
Prophylactic Antibiotics Before RFA for HCC
This randomized prospective study aims to investigate whether prophylactic administration of antibiotics has an influence on inflammatory markers, liver function test results, or the incidence of post-procedural infection in…
- Trial name
- NCT02534961
- Testing
- Cefazolin
- Where
- Taiwan
- Volunteers
- 600 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
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