Clinical trials: RCT
Anxiety Disorder of Adolescence
RCT of CBT Based C.A.T Project for Pakistani Adolescents With Anxiety Disorders.
Anxiety Disorders are the most prevalent mental health conditions among adolescents. The current randomized control trial aims to assess the efficacy of the C.A.T Project protocol among adolescents aged 14 to 17 years diagnosed…
- Trial name
- NCT07202715
- Testing
- CBT Based C.A.T Project- Intervention for Anxious Adolescents.
- Where
- 3 sites in Pakistan
- Volunteers
- 50 people
- Sponsor
- National University of Science and Technology
Partially Edentulous Maxilla, Mandible
Submerged vs. Nonsubmerged Single Laser-microgrooved Dental Implants.
Aim: to evaluate and compare radiographic marginal bone loss (MBL) and soft tissue parameters around submerged/two-stage and nonsubmerged/one-stage single implants with same tapered body design and surface, same thread design and…
- Trial name
- NCT03674762
- Testing
- Microgrooved dental implants
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Opioid Dependency
A Six-Month Randomized Controlled Trial (RCT) of Probuphine Safety and Efficacy in Opioid Addiction
Probuphine (buprenorphine implant) is an implant placed just below the skin containing buprenorphine (BPN). BPN is an approved treatment for opioid dependence. This study will confirm the efficacy of Probuphine vs.
- Trial name
- NCT01114308
- Testing
- Probuphine (buprenorphine implant), Buprenorphine
- Where
- 20 sites in United States
- Volunteers
- 287 people
- Sponsor
- Titan Pharmaceuticals
Sepsis, Severe Sepsis
RCT of Sepsis Machine Learning Algorithm
The focus of this study will be to conduct a prospective, multi-center randomized controlled trial (RCT) at Cape Regional Medical Center (CRMC), Oroville Hospital (OH), and UCSF Medical Center (UCSF) in which a machine-learning…
- Conditions
- Sepsis, Severe Sepsis, Septic Shock
- Trial name
- NCT03882476
- Testing
- InSight
- Volunteers
- healthy volunteers welcome
- Sponsor
- Dascena
Alzheimer's Disease
A Prospective Multicenter RCT Study of Deep Jugular Lymphovenous Anastomosis in the Treatment of Alzheimer's Disease
This research aims to observe the efficacy and safety of surgery compared with traditional medical treatment for moderate to severe dementia in Alzheimer's disease.
- Trial name
- NCT07060391
- Testing
- Deep cervical lymphatic-venous anastomosis, Donepezil drug treatment
- Volunteers
- 186 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Coronary Artery Disease
Acrobat Coronary Stent System Effectiveness European Study
The purpose of this randomized controlled trial (RCT) is to demonstrate the clinical benefit and impact on resource utilization of percutaneous coronary interventions (PCI) with the Svelte Acrobat Stent System compared to any…
- Trial name
- ACES (NCT01761591)
- Testing
- PCI with Svelte Acrobat, PCI with other BMS
- Where
- 12 sites in Belgium, France and 1 more
- Volunteers
- 300 people
- Sponsor
- Svelte Medical Systems Europe
Schizophreniform Disorders, Bipolar Disorder
REWRITALIZE Your Recovery - Evaluation of a Creative Writing Group Intervention
Health institutes call for psychosocial interventions and recovery-oriented approaches as supplement to pharmacological treatment for mental health disorders.
- Conditions
- Schizophreniform Disorders, Bipolar Disorder, Severe Depression, Ptsd
- Trial name
- REWR (NCT06251908)
- Testing
- Rewritalize, Standard mental health care
- Where
- 6 sites in Denmark
- Volunteers
- 300 people
- Sponsor
- Amager Hospital
Low Back Pain
Office Program Effects on Pain, Posture, Muscle Physiology, Stress, Ergonomics, and Quality of Life in LBP Workers
This interventional study aims to evaluate the effectiveness of an office worker's program in reducing low back pain and improving physical and psychosocial outcomes among office employees.
- Trial name
- NCT07250568
- Testing
- Exercise, Education, Advice
- Where
- Indonesia
- Volunteers
- 60 people
- Sponsor
- Suci Wahyu Ismiyasa
Gastrointestinal Erosions and/or Ulcers
Efficacy of Proton Pump Inhibitors in Gastrointestinal Erosions and/or Ulcers
The aim of this study is to collect the data of clinical efficacy and safety after the usage of bonoprazon and esomeprazole when the patients take NSAIDs more than 2 weeks and have gastrointestinal symptoms who have had…
- Trial name
- NCT03315676
- Testing
- Oral Bonoprazan, Oral Esomeprazol
- Where
- Japan
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Shinshu University
Behavior
Developing a Physically More Active Lifestyle Based on One's Own Values - RCT Among Sedentary Adults
The main objective of the study is to provide data of the effectiveness and feasibility of the Acceptance and Commitment Therapy in enhancing the physically active lifestyle among sedentary adults.
- Trial name
- NCT01796990
- Testing
- ACT, REF
- Where
- Finland
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Likes - Foundation for Sport and Health Sciences
Prematurity
Effect of Osteopathic Manipulative Treatment on Reduction of Pain in Complicated Newborns: RCT
The aim of the present 3 armed placebo control parallel group randomized control trial is to explore the extent to which osteopathic manipulative treatment is effective in reducing pain in a population of complicated newborns.
- Trial name
- NCT02146690
- Testing
- osteopathic manipulative treatment, usual care
- Where
- Italy
- Volunteers
- 225 people
- Sponsor
- European Institute for Evidence Based Osteopathic Medicine
Post-traumatic Stress Symptoms, Psychosocial Distress
An RCT of Trauma Focused-Cognitive Behavioral Therapy With Sexually Exploited, War-affected Girls in the DRC
To date, no RCT has examined the efficacy of Trauma-Focused Cognitive Behavioral Therapy with Sexually Exploited, War Affected Adolescent Girls in the Democratic Republic of Congo.
- Trial name
- NCT01483261
- Testing
- Trauma-Focused Cognitive Behavioral Therapy
- Where
- Republic of the Congo
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Paedophilia, Hebephilia
Study on the Effectiveness of Berlin Dissexuality Therapy as Part of the Model Project in Accordance With §65d SBG V
The main goal of this clinical trial is to learn if psychotherapy works to reduce consumption of child abuse imagages.
- Trial name
- BEDIT-RCT (NCT06607042)
- Testing
- Psychotherapy
- Volunteers
- 60 people
- Sponsor
- Charite University, Berlin, Germany
Dementia
Improving Wellbeing and Health for Care Home Residents During COVID-19
More than 400,000 people in the UK live in care homes. These individuals are particularly vulnerable to COVID-19; many are frail and the majority have concurrent physical health problems and dementia.
- Trial name
- COVIDWHELD (NCT04590469)
- Testing
- COVID WHELD
- Where
- United Kingdom
- Sponsor
- University of Exeter
Income, Infant, Newborn
Integrating Systems and Basic Income: Improving Outcomes for Families of Young Children
Early childhood is a critical period, laying the foundation for future growth and deveopment. This foundational period has an outsized effect, impacting health, well-being and achievement across one's lifespan. The U.S.
- Conditions
- Income, Infant, Newborn, Mothers, Poverty
- Trial name
- NCT07261254
- Testing
- Community Health Worker, Community Health Worker + Guaranteed Basic Income
- Where
- United States
- Volunteers
- 2,400 people
- Sponsor
- Stanford University
Non-Small Cell Lung Carcinoma, Compliance Behavior
Patient Navigation for Lung Cancer Screening in an Urban Safety-Net System
The study proposes to evaluate a patient navigation intervention among a sample of 446 individuals referred for CT-based lung cancer screening in an urban safety-net setting.
- Conditions
- Non-Small Cell Lung Carcinoma, Compliance Behavior, Prevention Harmful Effects
- Trial name
- NCT02758054
- Testing
- Patient Navigation
- Where
- United States
- Volunteers
- 447 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Sarcopenia, Connective Tissue Diseases in Old Age
RCT of Combination Effect of Vibration Treatment and HMB Supplementation on Myosteatosis and NMJ Degeneration
The investigators' pre-clinical study confirms the positive effects of combined treatment (VT + HMB) on reducing fat-to-lean tissue ratio, intramuscular fat infiltration and increasing muscle strength in sarcopenia animal model.
- Conditions
- Sarcopenia, Connective Tissue Diseases in Old Age, Musculoskeletal Abnormalities
- Trial name
- NCT05525039
- Testing
- Low-magnitude High-frequency Vibration, β-hydroxy β-methylbutyrate (HMB) supplement, Protein supplement
- Where
- 3 sites in Hong Kong
- Volunteers
- 200 people
- Sponsor
- Chinese University of Hong Kong
Interparental Conflict, Marital Conflict
Love Together, Parent Together: A Protocol for a Pilot Study of an Intervention for Interparental Couples With Young Children
The COVID-19 pandemic has created a population-level threat to social relationships that requires a population-level solution. Among those who are particularly vulnerable to heightened conflict are interparental couples with…
- Conditions
- Interparental Conflict, Marital Conflict, Marital Relationship, Internet-Based Intervention
- Trial name
- L2P2 (NCT05261022)
- Testing
- Love Together, Parent Together (L2P2)
- Where
- Canada
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- York University
Rectal Cancer
Robotic-assisted Versus Conventional Laparoscopic Approach for Rectal Cancer Surgery
This is a prospective randomized controlled study that was conducted on patients of both sexes and definite age group at National Cancer Institute-Egypt and with adenocarcinoma of the rectum located within 15 cm from the anal…
- Trial name
- NCT03589131
- Testing
- Total Operative time, Margin assessment, Conversion rate to open surgery
- Volunteers
- 57 people
- Sponsor
- National Cancer Institute, Egypt
Sepsis, Septic Shock
Early Administration of Vitamin C in Patients With Sepsis or Septic Shock in Emergency Departments
In this clinical trial the effect of early administration of Vitamin C is investigated in patients admitted at the emergency department with sepsis or septic shock.
- Conditions
- Sepsis, Septic Shock, Sepsis, Severe
- Trial name
- c-easie (NCT04747795)
- Testing
- Vitamin C, Normal saline
- Where
- 8 sites in Belgium
- Volunteers
- 301 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven