Clinical trials: RECURRENT PREGNANCY LOSS
Pregnancy, Miscarriage
Aspirin, Heparin and Miscarriage
Efficacy of low dose aspirin (LDA) versus LDA plus low-molecular-weight-heparin (LMWH) in patients with a history of recurrent miscarriages.
- Trial name
- NCT01917799
- Testing
- Aspirin, Heparin
- Where
- Libya
- Volunteers
- 150 people
- Sponsor
- University of Khartoum
Recurrent Pregnancy Loss
Treatment of Recurrent Pregnancy Loss Using Mesenchymal Stem Cells
Treatment of Recurrent pregnancy loss using mesenchymal stem cells capable of differentiation in the endometrial-decidual direction.
- Trial name
- NCT05520112
- Testing
- Mesenchymal stem cells capable of differentiation in the endometrial-decidual direction, Standard treatment according to the clinical protocols
- Where
- Belarus
- Volunteers
- 20 people
- Sponsor
- Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus
Thrombophilia
Fertility, Hypercoagulability, and Inflammation (FREYA) Registry
A PubMed search of "thrombophilia" and "infertility" yields only 98 articles, the majority found in foreign medical journals and subspecialty journals with narrow readerships.
- Trial name
- FREYA (NCT04537416)
- Testing
- No intervention
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Brigham and Women's Hospital
Recurrent Pregnancy Loss
Hydroxychloroquine in Unexplained Recurrent Pregnancy Loss
To investigate efficacy and safety of Hydroxychloroquin in improving pregnancy outcome in women with unexplained recurrent pregnancy loss .
- Trial name
- NCT05237843
- Testing
- Hydroxychloroquine
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Thrombophilia With Recurrent Pregnancy Loss
Diagnosis and Treatment Strategy of Recurrent Spontaneous Abortion Associated With Thrombophilla
In this clinical cohort study, the investigators observe the efficacy of low molecular weight heparin in the treatment of thrombophilia with recurrent pregnancy loss with a prospective randomized controlled trial.
- Trial name
- NCT02986594
- Testing
- Aspirin, Heparin
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Shanghai First Maternity and Infant Hospital
Abortion, Habitual
RECAB-ASA; Treatment of Recurrent Abortion With Aspirin
The aim of this study is to examine whether treatment with 75 mg aspirin daily compared with placebo could reduce the risk for a new miscarriage.
- Trial name
- RECAB-ASA (NCT02823743)
- Testing
- Aspirin
- Volunteers
- 400 people
- Sponsor
- Göteborg University
Recurrent Pregnancy Loss
Biweekly Follow-Up and At-Home Ultrasound Reduce Anxiety in Women With Recurrent Pregnancy Loss
Spontaneous pregnancy loss is a relatively common phenomenon, with 10-15% of clinically recognized pregnancies ending in miscarriage.1 Recurrent pregnancy loss (RPL) is a disorder defined by two or more failed pregnancies2.
- Trial name
- NCT05656846
- Testing
- PulseNmore ES™, Standard Ultrasound
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Chronic Endometritis
Hysteroscopy and CD138+ Plasma Cell Density in Chronic Endometritis
The goal of this observational study is to learn if a hysteroscopy exam alone can find chronic endometritis, a long-lasting inflammation of the lining of the uterus.
- Trial name
- NCT07733713
- Volunteers
- 100 people
- Sponsor
- Centro A.M.B.R.A. (Associazione Medici e Biologi per la Riproduzione Assistita)
Recurrent Miscarriage
Nutritional Deficiency and Recurrent Miscarriage
This prospective cohort study primarily aims to examine the association between blood niacin levels and recurrent miscarriage.
- Trial name
- NCT05267678
- Testing
- No intervention
- Where
- China
- Volunteers
- 499 people
- Sponsor
- Westlake University
Pregnancy Loss
Role of Low-Molecular-Weight Heparin in Unexplained Recurrent Pregnancy Loss
Using low-molecular-weight heparin (LMWH), outcomes such as live birth rate and the occurrence of pregnancy complications are some of the variables reported in some studies, with varying degrees of success.
- Trial name
- NCT06484634
- Testing
- Low molecular weight heparin
- Where
- Pakistan
- Volunteers
- 175 people
- Sponsor
- RESnTEC, Institute of Research
Abortion, Spontaneous, Abortion, Habitual
RPL: Interval to Live Birth and Adverse Perinatal Outcomes
This will be a retrospective observational cohort study utilizing the data from the British Columbia Perinatal Data Registry (BCPDR).
- Conditions
- Abortion, Spontaneous, Abortion, Habitual, Birth Intervals, Pregnancy Loss
- Trial name
- NCT04360564
- Testing
- Recurrent pregnancy loss
- Where
- Canada
- Volunteers
- 140,000 people, healthy volunteers welcome
- Sponsor
- Children's & Women's Health Centre of British Columbia
Pre-Eclampsia
Hydroxychloroquine May be Beneficial for Preeclampsia
The purpose of this research is to investigate the impact of hydroxychloroquine on the incidence of hypertensive pregnancy disorders in women with a history of recurrent spontaneous abortion (RSA).
- Trial name
- NCT06020378
- Testing
- Hydroxychloroquine
- Where
- China
- Volunteers
- 462 people
- Sponsor
- RenJi Hospital
Microbiome, Recurrent Pregnancy Loss
Elucidating the Microbiome in Patients With Recurrent Pregnancy Loss
Recurrent pregnancy loss (RPL) is defined as 2 or more consecutive miscarriages1 This condition affects about 1-3% of couples during their reproductive years.
- Trial name
- NCT05612620
- Testing
- coulture
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assuta Ashdod Hospital
Endometrial Clear Cell Adenocarcinoma, Ovarian Clear Cell Cystadenocarcinoma
Dasatinib in Treating Patients With Recurrent or Persistent Ovarian, Fallopian Tube, Endometrial or Peritoneal Cancer
This phase II trial studies how well dasatinib works in treating patients with ovarian, fallopian tube, endometrial, or peritoneal cancer that has come back or is persistent.
- Conditions
- Endometrial Clear Cell Adenocarcinoma, Ovarian Clear Cell Cystadenocarcinoma, Recurrent Fallopian Tube Carcinoma, Recurrent Ovarian Carcinoma
- Trial name
- NCT02059265
- Testing
- Dasatinib, Laboratory Biomarker Analysis
- Where
- 227 sites in United States
- Volunteers
- 35 people
- Sponsor
- National Cancer Institute (NCI)
Recurrent Pregnancy Losses, Positive Anti Phospholipid Syndrome
Preconceptional Thromboprophylaxis in Recurrent PREGNANCY LOSSES Caused by Antiphospholipid Syndrome
Preconceptional use of low molecular weight heparin (enoxaparin) and aspirin in patient with recurrent miscarriages with positive anti phospholipid antibodies increase the implantation rate and the duration of pregnancy with low…
- Trial name
- NCT01661439
- Testing
- low molecular weight heparin (enoxeparine)
- Where
- Egypt
- Volunteers
- 316 people, healthy volunteers welcome
- Sponsor
- Woman's Health University Hospital, Egypt
Recurrent Miscarriage
3D Ultrasound to Assess in Recurrent Miscarriage
This observational study aims to compare the prevalence of acquired abnormalities of the uterus (fibroids, polyps, intrauterine adhesions, adenomyosis) in women who have recurrent miscarriages with the fertile population.
- Trial name
- 3D-ARM (NCT06164015)
- Testing
- 3D Ultrasound scan with power Doppler angiography
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University Hospitals of Derby and Burton NHS Foundation Trust
Recurrent Miscarriage, Infertility
Iron Status in Female Infertility and Recurrent Miscarriage
Multiple studies suggest a link between the iron status and the development of the endometrium. Therefore, a sufficient iron supply seems to relevant for female fertility and reproduction.
- Conditions
- Recurrent Miscarriage, Infertility, Iron-deficiency
- Trial name
- NCT05034250
- Testing
- Blood sample
- Where
- Austria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Abortion, Recurrent
Platelet Indices and Recurrent Pregnancy Loss
The aim of this study was to evaluate relationship between platelet indices, red blood cell indices and recurrent pregnancy loss.
- Trial name
- NCT05190796
- Testing
- platelet indices
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Menoufia University
Recurrent Miscarriage
Use of Platelet Indices for Prediction of Recurrent Miscarriage
Platelet indices might be a marker for platelet activation, and thus could predict thrombosis. This might be the cause in some cases of recurrent miscarriage.
- Trial name
- NCT03710226
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Rania Hassan Mostafa
Thrombophilia
Thrombin Generation and Gestational Outcome
In total 120 pregnant women's with history of recurrent miscarriages, are planned for inclusion in this trial. After signing an informed consent a blood sample will be obtained from each participant.
- Trial name
- NCT02139670
- Where
- Israel
- Volunteers
- 29 people
- Sponsor
- HaEmek Medical Center, Israel