Clinical trials: RENAL INSUFFICIENCY, CHRONIC
Heart Failure, Chronic Obstructive Pulmonary Disease
Metabolic Changes in Patients With Chronic Cardiopulmonary Disease
This study aims to evaluate prevalence of sarcopenia and cachexia in patients with chronic cardiopulmonary disease. The investigators will also investigate metabolic disorders like glucose metabolism, presence of metabolic…
- Conditions
- Heart Failure, Chronic Obstructive Pulmonary Disease, Malignancy, Chronic Kidney Disease
- Trial name
- NCT02550808
- Where
- Slovenia
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- General and Teaching Hospital Celje
Renal Insuffiency, Kidney Transplantation
Pre-emptive Kidney Transplantation Quality of Life
The main objective is to assess the psychological impact of pre-emptive kidney transplantation on patients' quality of life taking into account psychological adjustment (response shift), compared to patients who have experienced…
- Trial name
- PreKiTQoL (NCT02154815)
- Testing
- Questionnaires : Patient-Reported Outcomes
- Where
- 5 sites in France
- Volunteers
- 390 people
- Sponsor
- Nantes University Hospital
End-stage Kidney Disease, CD4 T Cells
Effects of High Cut-off (HCO) Hemodialysis on Central Memory CD4+ T and Treg Cells in Patients With End-stage Kidney Disease
In this study, the investigators will evaluate whether CD4+ TCM producing effector cytokines can be distinguished on the basis of their expression of the IL-7 receptor alpha-chain (CD127).
- Conditions
- End-stage Kidney Disease, CD4 T Cells, Central Memory T Cells, Regulatory T Cells
- Trial name
- NCT01103076
- Testing
- Polyamide HD membrane
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier du Centre du Valais
Chronic Kidney Disease
AXOS and Microbial Metabolites in CKD
Chronic kidney disease is associated with the accumulation of various metabolites, i.e., uremic retention solutes. Evidence is mounting that the colonic microbiota contributes substantially to these uremic retention solutes.
- Trial name
- NCT02141815
- Testing
- Arabinoxylan-oligosaccharides, Maltodextrine
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Chronic Kidney Diseases, Coronary Heart Disease
Cardiovascular-Renal Adverse Prognosis Assessment System for Coronary Heart Disease With Chronic Kidney Disease Based on Metabolomics
Coronary heart disease (CHD) combined with chronic kidney disease (CKD) affects a substantial portion of the population and carries a significant disease burden, often leading to poor outcomes.
- Conditions
- Chronic Kidney Diseases, Coronary Heart Disease, Lipid Metabolism Disorders
- Trial name
- CRUISE-MET (NCT06383208)
- Testing
- lipid metabolomics
- Where
- China
- Volunteers
- 470 people, healthy volunteers welcome
- Sponsor
- China-Japan Friendship Hospital
Chronic Kidney Disease
Effects of Low Protein Diet Supplemented Keto-/Amino Acid in Preventing the Progression of Chronic Kidney Disease (CKD)- ELPD Study
The purpose of this study is to determine whether low protein diet and very low protein diet supplemented keto-/amino acid is effective in preventing the progression of chronic kidney disease (CKD , stage 3b and 4).
- Trial name
- ELPD-CKD (NCT01418508)
- Testing
- low protein diet plus α-keto acid, very low protein diet plus α-keto acid
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking Union Medical College Hospital
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis, End Stage Renal Disease
Maintaining or Stopping Immunosuppressive Therapy in Patients With ANCA Vasculitis and End-stage Renal Disease
This prospective randomized trial aims to evaluate the feasibility, risk and benefit of the discontinuation of immunosuppressive maintenance treatments in AAV (Antineutrophil Cytoplasmic Autoantibodies (ANCA)-associated…
- Trial name
- MASTER-ANCA (NCT03323476)
- Testing
- Discontinuation (or not initiation) of Immunosuppressive Therapy, Maintenance (or initiation) of immunosuppressive treatment: Imurel®, Mabthera®,Cellcept®, Cortancyl®
- Where
- 57 sites in France
- Volunteers
- 136 people
- Sponsor
- Centre Hospitalier Departemental Vendee
Chronic Kidney Disease
The Analysis of Correlation About the Spot Urine Sodium and the Blood Pressure in General Population According to the Income Level
Increasing sodium intake raises blood pressure. And high salt intake could hinder the management of chronic disease. Much previous research has confirmed that dietary habits are affected by economic status.
- Trial name
- NCT01960608
- Testing
- 24_hours_urine_sodium
- Where
- South Korea
- Volunteers
- 7,000 people
- Sponsor
- Inje University
Secondary Hyperparathyroidism, Tertiary Hyperparathyroidism
Intraoperative Parathyroid Hormone Monitoring to Guide Surgery in Renal hyperparathyroIdism
The goal of this pilot clinical is to determine the feasibility of a fully powered clinical trial to determine the effectiveness of intraoperative parathyroid hormone (IOPTH) criteria in guiding surgery for secondary and tertiary…
- Trial name
- PEREGRINE (NCT06542315)
- Testing
- Intraoperative parathyroid hormone (IOPTH) monitoring
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- McMaster University
Low-Level Light Therapy, Renal Insufficiency, Chronic
Effects of Low Level Laser Therapy on Functional Capacity and DNA Damage of Patients With Chronic Kidney Failure
This study aims to verify the effects of low level laser therapy (LLLT) on functional capacity, DNA damage, lower limbs muscle strength, quadriceps muscle architecture, muscle pain and perception of lower limb fatigue…
- Conditions
- Low-Level Light Therapy, Renal Insufficiency, Chronic, Renal Dialysis, Clinical Trial
- Trial name
- NCT03250715
- Testing
- Low Level Laser Therapy
- Where
- Brazil
- Volunteers
- 28 people
- Sponsor
- Federal University of Health Science of Porto Alegre
End Stage Kidney Disease
Effect of 25-hydroxyvitamin D and a Structured Exercise Program on Dialysis Patients
This study aims to examine the effect of 25 hydroxyvitamin D supplementation and a structured exercise program on the exercise capacity and quality of life of haemodialysis patients with 25 hydroxyvitamin D insufficiency.
- Trial name
- NCT00798993
- Testing
- Structured Exercise program, Cholecalciferol (25-Hydroxyvitamin D), Usual exercise
- Where
- Australia
- Volunteers
- 19 people
- Sponsor
- Sir Charles Gairdner Hospital
Chronic Kidney Disease
Reduced Calorie Diet Intervention in Kidney Transplant Recipients
The purpose of this study is to measure the effect of a reduced calorie diet intervention in new kidney transplant recipients on the outcomes weight gain, oxidative stress, and insulin resistance.
- Trial name
- NCT00994838
- Testing
- reduced calorie diet
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Vanderbilt University
End-Stage Renal Disease, Kidney Failure
Treatment of Children With Kidney Transplants by Injection of CD4+CD25+FoxP3+ T Cells to Prevent Organ Rejection
T regulatory cells (T regs) are responsible for immune tolerance in solid organ transplant patients. This study will evaluate the treatment of children with kidney transplants either with Campath and other immune system…
- Trial name
- NCT01446484
- Testing
- CD4+CD25+CD127lowFoxP3+ T regulatory cells injection, Alemtuzumab, Mycophenolate mofetil
- Where
- 2 sites in Russia
- Volunteers
- 30 people
- Sponsor
- Pirogov Russian National Research Medical University
Chronic Renal Insufficiency, Pruritus
The Efficacy of VR and AR on Pruritus
The research will be conducted randomly in order to determine the effect of VR and AR on pruritus symptom.
- Conditions
- Chronic Renal Insufficiency, Pruritus, Itch
- Trial name
- NCT04289038
- Testing
- Autogenic Relaxation, virtual reality game application, kidney function narration
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Kidney Failure, Chronic
Effect of Exercise With Virtual Reality in Hemodialysis Patients
Background. An increase in inflammatory biomarkers is associated with impaired kidney function and increased cardiovascular risk and mortality.
- Trial name
- NCT05606484
- Testing
- Exercise with non-immersive virtual reality, Exercise with a static pedal
- Volunteers
- 80 people
- Sponsor
- Universidad Miguel Hernandez de Elche
Chronic Hepatitis C Virus, Hepatitis C Virus
A Study to Evaluate the Efficacy and Safety of ABT-493/ABT-530 in Japanese Adults With Chronic Hepatitis C Virus Infection
The purpose of this phase 3, multicenter study is to evaluate the efficacy and safety of ABT-493/ABT-530 in Japanese adults with chronic Hepatitis C Virus (HCV)-infected, HCV direct-acting antiviral agent (DAA) treatment-naïve…
- Trial name
- CERTAIN-1 (NCT02707952)
- Testing
- ABT-493/ABT-530, OBV/PTV/r
- Volunteers
- 295 people
- Sponsor
- AbbVie
Chronic Kidney Disease, Hemodialysis
Effect of Bedtime Mindfulness Meditation on Anxiety and Spiritual Well-Being in Hemodialysis Patients
This study evaluates whether Bedtime Meditation Based on Mindfulness (BM-BOM) can reduce anxiety and improve spiritual well-being in patients undergoing hemodialysis.
- Conditions
- Chronic Kidney Disease, Hemodialysis, Anxiety, Spiritual Well-being
- Trial name
- BM-BOM (NCT07378748)
- Testing
- Bedtime Meditation Based on Mindfulness (BM-BOM), Passive Rest (Control)
- Where
- Indonesia
- Volunteers
- 58 people
- Sponsor
- Universitas Muhammadiyah Surakarta
Pleural Effusion, Chronic Kidney Disease
Pleural Effusion Types in Chronic Kidney Disease
The purpose of this observational study is to understand the causes of pleural effusion (a buildup of fluid around the lungs) in patients with advanced Chronic Kidney Disease (CKD Stages 3 to 5).
- Trial name
- NCT07547852
- Volunteers
- 100 people
- Sponsor
- Assiut University
Chronic Kidney Diseases, Hypertension
Electronic Tools to Increase Recognition and Improve Primary Care Management for Hypertension in Chronic Kidney Disease
In this project the investigators will create computer reminders through user-centered design and will validate the logic using retrospective electronic health record (EHR) data.
- Trial name
- NCT03679247
- Testing
- Intervention, Control
- Where
- United States
- Volunteers
- 2,026 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
End Stage Renal Disease
Multicentre, Open Label, Randomized, Two-arm, Parallel-group Study to Assess Efficacy and Safety of ENVARSUS® Compared With Tacrolimus Used as Per Current Clinical Practice in the Initial Maintenance Setting in de Novo Kidney Transplant Patients
The purpose of the study is to compare tacrolimus dosing of the new Envarsus®-based immunosuppressive regimen with current clinical practice (Prograf or Advagraf) over 6 months following de novo renal transplantation in a…
- Trial name
- STEADY (NCT02432833)
- Testing
- ENVARSUS®, PROGRAF®, ADVAGRAF®
- Where
- Italy
- Volunteers
- 428 people
- Sponsor
- Chiesi Farmaceutici S.p.A.
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