Clinical trials: RT-PCR
COVID-19
Clinical Validation of Breath Analyser Tests for Diagnosis of COVID-19.
The Sponsor has developed a rapid screening tool intended to determine if the subject tested is COVID-19-free (Negative to COVID-19).
- Trial name
- NCT05094674
- Testing
- Breath Sample analysis
- Where
- United Kingdom
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Tera Group
COVID
Detection of COVID-19 (SARS-CoV-2) in the Semen of COVID+ Patients (Positive RT-PCR on a Nasopharyngeal Swab)
The objective of this study is to look for the presence of SARS-CoV-2 in the semen of patients diagnosed with COVID+ based on RT-PCR analysis of nasopharyngeal swabs.
- Trial name
- COVISPERM (NCT04460534)
- Testing
- diagnostic
- Where
- France
- Volunteers
- 52 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
COVID-19
Efficacy of a Multiplex BangasureTM RT-PCR Kit for the Detection of COVID-19
The outbreak of the severe acute respiratory syndrome (SARS) corona virus (CoV)-2 continues to increase globally. To control the coronavirus disease 2019 (COVID-19) transmission, diagnose is very important step which would help…
- Trial name
- COVID-19 (NCT05190016)
- Where
- Bangladesh
- Volunteers
- 150 people
- Sponsor
- DR. MALA KHAN
Sars-CoV2
Prevalence of COVID-19 Infection Among HCW in a French University Hospital
The objective of this study is to determine the prevalence of SARS-Cov2 infection among health care workers exposed of Lille University Hospital, to describe its evolution during the epidemic taking into account the influence of…
- Trial name
- EXPOCOVIA (NCT04371692)
- Testing
- self-administered questionnaire, SARS-Cov2 testing
- Where
- France
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Non-Metastatic Ewings Sarcoma
Prognostic Value of a Positive RT-PCR Test in Patients With Ewing Sarcoma
This study will determine whether the results of a test called reverse transcriptase-polymerase chain reaction (RT-PCR) correlate with clinical outcomes in patients with Ewing sarcoma, and if they can be used to help identify…
- Trial name
- NCT00339898
- Where
- United States
- Volunteers
- 414 people
- Sponsor
- National Cancer Institute (NCI)
SARS-CoV-2 Infection, COVID-19
Evaluation of Concordance Between Exhaled Air Test (eBAM-CoV) and RT-PCR to Detect SARS-CoV-2
During the COVID-19 pandemic, testing primarily relied on the use of nasopharyngeal swabs to detect the SARS-CoV-2 virus, responsible for the disease.
- Conditions
- SARS-CoV-2 Infection, COVID-19, Coronavirus
- Trial name
- eBAM_CoV (NCT06099795)
- Testing
- eBAM Cov Testing
- Where
- 2 sites in France
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Healthy Participants
COVID-19 Study Assessing the Efficacy and Safety of Anti-Spike SARS CoV-2 Monoclonal Antibodies for Prevention of SARS CoV-2 Infection Asymptomatic in Healthy Adults and Adolescents Who Are Household Contacts to an Individual With a Positive SARS-CoV-2 RT-PCR Assay
Primary Objectives: Cohort A: To evaluate the efficacy of REGN10933+REGN10987 compared to placebo in preventing symptomatic SARS-CoV-2 infection (broad-term) confirmed by RT-qPCR Cohort A and Cohort A1: To evaluate the safety and…
- Trial name
- NCT04452318
- Testing
- REGN10933 + REGN10987
- Where
- 134 sites in United States, Moldova and 1 more
- Volunteers
- 3,303 people, healthy volunteers welcome
- Sponsor
- Regeneron Pharmaceuticals
High Sensitivity and Specificity (With 95% Confidence Interval) of RealDetect™ COVID-19 RT-PCR Kit
Performance Evaluation of RealDetect™ COVID-19 RT-PCR Kit for the Detection of SARS-CoV-2 Virus
The novel Severe acute respiratory syndrome coronavirus 2 (SARS-C0V 2) originated in Wuhan, China in December 2019. As of April 15 2020, the virus has spread across 213 countries/territories with 1,914,916 cases and 123,010…
- Trial name
- NCT04403672
- Testing
- performance evaluation study of RealDetect RT-PCR Kit for COVID-19 detection
- Where
- Bangladesh
- Volunteers
- 120 people
- Sponsor
- Bangladesh Medical Research Council (BMRC)
Influenza
Ellume.Lab Flu A+B Test and iTreat Flu A+B Flu Test Performance Versus Viral Culture and Reverse Transcriptase Polymerase Chain Reaction.
The primary purpose of this study is to validate the sensitivity and specificity of the iTreat Flu A+B Test and the ellume.lab Flu A+B Test in detecting influenza A and influenza B as compared to viral culture.
- Trial name
- NCT03248960
- Testing
- iTreat Flu A+B Test, ellume.lab Flu A+B Test, Reverse Transcriptase Polymerase Chain Reaction (RT-PCR)
- Where
- 8 sites in Australia
- Volunteers
- 381 people
- Sponsor
- Ellume Pty Ltd
COVID-19
Geriatric COVID-19 Serology
Coronaviruses are important human and animal pathogens. At the end of 2019, a new coronavirus was identified as the cause of a cluster of pneumonia cases in Wuhan, a city in China's Hubei province.
- Trial name
- SeroGerCov (NCT05109546)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Strasbourg, France
Minimal Residual Disease, Fertility Preservation
Contamination of Testicle Tissue by RT-PCR in Participants With Solid Tumors
For prepubertal patients, cryopreservation of testicular tissue is the only option available to preserve their fertility before cancer treatment.
- Trial name
- TESTIMAR (NCT02400970)
- Testing
- malignant cells
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Clermont-Ferrand
Frenulum; Hypertrophy, Diode Laser
Diode Laser Versus Conventional Frenectomy in Children
This prospective, randomized, open-label, parallel-group clinical trial aims to compare diode laser frenectomy with conventional scalpel frenectomy in children aged 8-12 years with a clinical indication for maxillary labial…
- Conditions
- Frenulum; Hypertrophy, Diode Laser, Frenectomy, RT-PCR
- Trial name
- NCT07853599
- Testing
- Diode Laser Frenectomy, Conventional Scalpel Frenectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Yuzuncu Yil University
Pathologically Proven Stage I, II and III Non-Small Cell Lung Cancer (NSCLC)
Analysis of the Incidence of Expression of Tumor Antigens in Pathologically Proven Stage I, II and III Non-Small Cell Lung Cancer(NSCLC) in Asiatic Patients
This study aims to investigate the expression of Melanoma-associated antigen 3 (MAGE-A3), Melanoma-associated antigen C2 (MAGE-C2), New York esophageal squamous cell carcinoma 1 (NY-ESO-1), L antigen family member 1 (LAGE-1)…
- Trial name
- NCT01837511
- Testing
- Data acquisition and analysis
- Where
- 3 sites in Singapore, South Korea
- Volunteers
- 377 people
- Sponsor
- GlaxoSmithKline
Maternal Fetal Infection Transmission, COVID-19
Maternal-foetal Transmission of SARS-Cov-2
One case of maternal-fetal transmission of SARS Cov-2 was published (1). Ig M and Ig G were found at two hours after birth of a new born from a mother COVID-19.
- Conditions
- Maternal Fetal Infection Transmission, COVID-19, SARS-CoV 2
- Trial name
- TMF-COVID-19 (NCT04395924)
- Testing
- Diagnosis of SARS-Cov2 by RT-PCR and : IgG, Ig M serologies in the amniotoc fluid, the blood cord and the placenta
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Breast Cancer, Triple Negative Breast Cancer
Vabb After Neoadjuvant Therapy to Avoid Surgery-pCR to Avoid Breast Surgery
This single arm study aims to evaluate the efficacy and safety of a non-surgical approach, consisting of radiotherapy (RT) alone, for patients who have achieved a complete pathological response (pCR) following neoadjuvant…
- Conditions
- Breast Cancer, Triple Negative Breast Cancer, HER2-positive Breast Cancer, Neoadjuvant Chemotherapy
- Trial name
- BETTY-CRASY (NCT06281210)
- Testing
- Omission of surgical treatment
- Where
- 2 sites in Italy
- Volunteers
- 77 people
- Sponsor
- European Institute of Oncology
Schizophrenia
Disturbances of Kynurenine Pathway of Trytophan Metabolism in Schizophrenia: A Quantitative Reverse Transcription Polymerase Chain Reaction (RT-PCR) Study
In this pilot study, the investigators propose to characterize the pattern of activation of the kynurenine pathway of tryptophan metabolism in peripheral macrophages of patients with schizophrenia.
- Trial name
- NCT00573300
- Testing
- Phlebotomy
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- North Suffolk Mental Health Association
COVID19
Hydroxychloroquine Azithromycin COVID-19 Pregnancy Trial
Up to date, and since December 31st 2019, 2 520 522 cases of COVID-19 including 176 786 deaths, have been reported worldwide. Global efforts are made to save lives and decrease morbidity by evaluating therapeutic strategies.
- Trial name
- HASCOPT (NCT04365231)
- Testing
- Hydroxychloroquine and azithromycin treatment, conventional management of patients
- Sponsor
- Hospital St. Joseph, Marseille, France
HIV Infections
Safety and Effectiveness of a Three-Drug Combination Treatment for Recently Infected or Converted HIV Patients
The purpose of this study is to determine the safety and effectiveness of stavudine (d4T), didanosine (ddI), and BMS-232632 when given early in the course of HIV infection.
- Trial name
- NCT00007202
- Testing
- Atazanavir, Stavudine, Didanosine
- Where
- 5 sites in United States, Brazil
- Volunteers
- 55 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Covid19
Correlation Between Cycle Threshold (Ct) Values in COVID-19, Health Status and Laboratory Biomarkers in the Population of Medellin- Colombia Evaluated in a Specialized Laboratory.
This study will evaluate the correlation between the symptomaticity, Ct value, laboratory biomarkers associated to COVID-19 and the disease progression in hospitalized patients and outpatients with SARS-CoV2 infection diagnosed…
- Trial name
- NCT05067920
- Testing
- Levels of SARS-COV-2 antibodies, rRT-PCR SARS-Cov-2, Hematological and immunological biomarkers
- Where
- Colombia
- Volunteers
- 120 people
- Sponsor
- Universidad de Antioquia
Gastric Cancer
Quantitative Detection of CEA mRNA in the Smog and Tissue Exudate Whole Process Collected During Laparoscopic (Robotic) Radical Gastrectomy in Gastric Cancer Patients
The purpose of this SMOG 01 study is to observe the possibility of intraperitoneal dissemination of tumor cells throughout the entire laparoscopic (robotic) radical gastrectomy for gastric cancer and explore its related…
- Trial name
- NCT06076265
- Testing
- Radical Gastric Cancer Surgery
- Where
- China
- Volunteers
- 80 people
- Sponsor
- The Affiliated Hospital of Qingdao University