Clinical trials: RYGB
Internal Hernia
CTA for Internal Herniation After RYGB Surgery
Introduction: Morbid obesity, defined as a body mass index (BMI) of over 40 kg/m2, is globally an imminent health threat. Conservative therapies do often not yield the desired result.
- Trial name
- CTA-IH (NCT03114761)
- Testing
- CT angiography
- Where
- Netherlands
- Volunteers
- 12 people
- Sponsor
- Rijnstate Hospital
Obesity
MGB/OAGB Versus RYGB After Failed Sleeve
Sleeve Gastrectomy is the most performed bariatric procedure worldwide. But a growing number of data documents that some patients have to be surgical revised due to weight regain or gastro-esophageal reflux disease.
- Trial name
- NCT03526783
- Testing
- Roux en Y gastric bypass, Mini/One anastomosis gastric bypass
- Where
- Germany
- Volunteers
- 55 people
- Sponsor
- Sana Klinikum Offenbach
Obese
Safety and Preliminary Effectiveness of the BaroSense Articulating Circular Endoscopic (ACE) Stapler for Plication of Dilated Post-surgical Gastric Anatomy
The BaroSense Articulating Circular Endoscopic (ACE) Stapler is an investigational instrument indicated for endoluminal trans-oral tissue approximation and ligation in the gastrointestinal tract.
- Trial name
- NCT01388673
- Testing
- BaroSense ACE Stapler for plication of dilated post-surgical gastric anatomy
- Sponsor
- BaroSense Inc.
Bariatric Surgery
Evaluate the Efficacy and Safety of SASI Compared with RYGB in the Treatment of Obesity and Related Metabolic Diseases
Single anastomosis sleeve ileal bypass (SASI) is an improved surgical technique for sleeve gastrectomy (SG), which combines the advantages of SG and Roux-en-Y gastric bypass (RYGB) while avoiding their disadvantages,in order to…
- Trial name
- NCT06598267
- Testing
- SASI, RYGB
- Where
- China
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Obesity
Endomina Post RYGB
Surgery is the only effective treatment for morbid obesity and can be divided into restrictive surgeries (Lap Band and Sleeve gastrectomy), malabsorptive surgeries (Biliary pancreatic deviation and duodenal switch) or a…
- Trial name
- NCT03675035
- Testing
- Endomina
- Where
- Belgium
- Volunteers
- 16 people
- Sponsor
- Erasme University Hospital
Post Bariatric Hypoglycemia
Avexitide for Treatment of Post-Bariatric Hypoglycemia
AVX-001 (LUCIDITY) is a Phase 3 study to evaluate avexitide compared to placebo in participants with post bariatric hypoglycemia (PBH) related to Roux-en-Y gastric bypass (RYGB).
- Trial name
- LUCIDITY (NCT06747468)
- Testing
- Avexitide
- Where
- 21 sites in United States
- Volunteers
- 75 people
- Sponsor
- Amylyx Pharmaceuticals Inc.
Obesity
Comparison of Body Composition Changes With Weight Loss Interventions
This study is being done to compare the effects of a newer class of weight loss medications to weight loss surgery on the body's muscle, metabolism, and side effects over time.
- Trial name
- REFORM (NCT07115069)
- Testing
- GLP-1 receptor agonist, Gastric Bypass Surgery (laparoscopic), Gastric Bypass Surgery (robotic)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Vanderbilt University Medical Center
Obesity
Evaluation of the Absorption Rate From Different Oral Fe-supplements in Obese Volunteers Pre- and Post-RYGB
Obese volunteers who have scheduled a gastric bypass (RYGB) in UZ Leuven will be asked to participate in a cross-over study using commercial available iron supplements.
- Trial name
- NCT02569593
- Testing
- Iron supplements, more specific Ferrodyn and Vista Ferrum
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- KU Leuven