Clinical trials: Radiation, open to volunteers
Ion Beam Radiation Therapy for Tumor Patients
Ion Therapy Patient Registry
The purpose of the study is the prospective and standardized data collection of patients treated with ion therapy at MedAustron.
- Trial name
- REGI-MA-002015 (NCT03049072)
- Testing
- Protons and Carbon Ions
- Where
- Austria
- Volunteers
- 2,800 people
- Sponsor
- EBG MedAustron GmbH
Esophageal Squamous Cell Carcinoma
Phase II Study of Different Doses of Radiotherapy Combined With Sintilimab in the Treatment of Locally Advanced Esophageal Squamous Cell Carcinoma
This study is aimed to evaluate the efficacy and safety of different doses of radiotherapy combined with sintilimab in locally advanced esophageal squamous cell carcinoma.
- Trial name
- NCT06468644
- Testing
- chemoradiotherapy （CRT）+sintilimab 1, CRT+sintilimab 2
- Volunteers
- 60 people
- Sponsor
- Fujian Cancer Hospital
Breast Cancer
Breast Reconstruction and Neoadjuvant Radiotherapy
The purpose the BRENAR pilot study is to assess acute post-surgical complications following mastectomy and immediate breast reconstruction after neoadjuvant radiotherapy (NART).
- Trial name
- BRENAR (NCT05216900)
- Testing
- Neoadjuvant radiotherapy
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- UMC Utrecht
Anaplastic Astrocytoma, IDH-Wildtype, Anaplastic Oligoastrocytoma
Chemotherapy and Radiation Therapy for the Treatment of IDH Wildtype Gliomas or Non-histological (Molecular) Glioblastomas
This phase II trial studies how well temozolomide and radiation therapy work in treating patients with IDH wildtype historically lower grade gliomas or non-histological molecular glioblastomas.
- Conditions
- Anaplastic Astrocytoma, IDH-Wildtype, Anaplastic Oligoastrocytoma, Anaplastic Oligodendroglioma, Diffuse Astrocytoma, IDH-Wildtype
- Trial name
- NCT04623931
- Testing
- Quality-of-Life Assessment, Questionnaire Administration, Radiation Therapy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- M.D. Anderson Cancer Center
Erythrocyte Destruction
A Multi-dimensional Evaluation of the Effects of Linear Accelerator X-ray Irradiation on Red Blood Cells
This study aims to investigate the effects of linear accelerator X-ray irradiation on the structure, mechanics and functional characteristics of red blood cells recovered from patients with malignant tumors during surgery.
- Trial name
- NCT07416045
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Breast Cancer Female
Dermatitis During Adjuvant Irradiation for BREAst Cancer:
In the randomized DAI-BREAC trial, a reminder app will be prospectively tested that reminds breast cancer patients four times each day to perform the required skin care.
- Trial name
- DAI-BREAC (NCT06483477)
- Testing
- Standard skin care, Reminder App
- Where
- 5 sites in Denmark, Germany
- Volunteers
- 268 people
- Sponsor
- University Hospital Schleswig-Holstein
Doxorubicin Induced Cardiotoxicity, Doxorubicin Induced Cardiomyopathy
The Impact of Using Nicorandil for the Prevention of Doxorubicin-Induced Cardiotoxicity
Breast cancer is one of the world's most common cancers in females. Most of the chemotherapy protocols used to treat breast cancer involve doxorubicin. Doxorubicin has a very significant antitumor effect on breast tumors.
- Conditions
- Doxorubicin Induced Cardiotoxicity, Doxorubicin Induced Cardiomyopathy, Doxorubicin, Doxorubicin Adverse Reaction
- Trial name
- NICBREASTRCT (NCT07897409)
- Testing
- Nicorandil Oral Tablet, Adriamycin (Doxorubicin)
- Where
- Egypt
- Volunteers
- 146 people
- Sponsor
- Universiti Sains Malaysia
Liver Cancer
vGRID SBRT: A Phase I Clinical Trial in Unresectable or Metastatic HCC
This trial will provide the maximum tolerated dose for radiation therapy for liver tumors and describe the toxicity profile using the vGRID therapy technique.
- Trial name
- vGRID SBRT (NCT05727787)
- Testing
- Stereotactic Body Radiation Treatment
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Kansas Medical Center
Radiation-induced Intestinal Injury
Study on Biomarkers of Radiation-Induced Intestinal Injury
1. To identify biomarkers of radiation-induced intestinal injury; 2. To develop a predictive model for radiation-induced intestinal injury.
- Trial name
- NCT07528287
- Volunteers
- 220 people
- Sponsor
- Tongji Hospital
Cardiotoxicity, Pediatric Cancer
Cardiotoxicity Assessment Through Comprehensive Heart Imaging to Predict Heart Failure
Anthracycline chemotherapies (e.g. doxorubicin, daunorubicin) are commonly given to treat pediatric cancer, and carry a risk of cardiotoxicity.
- Conditions
- Cardiotoxicity, Pediatric Cancer, Heart Failure
- Trial name
- CATCH-HF (NCT04262830)
- Testing
- Cardiac magnetic resonance imaging (MRI), Accelerometer physical activity monitoring
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Hari Narayan
HCC
Sintilimab Combined With Stereotactic Body Radiotherapy as Neoadjuvant Therapy for Resectable Hepatocellular
This study is a prospective, randomized controlled, phase II trial evaluating the efficacy and safety of neoadjuvant therapy with Sintilimab combined with SBRT in patients with resectable hepatocellular carcinoma.
- Trial name
- NCT07352007
- Testing
- SBRT, Sintilimab, Surgery
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Lei ZHAO
Oral Cavity Squamous Cell Carcinoma, Stage I Lip and Oral Cavity Cancer AJCC v8
Personalized Neck Radiation Therapy Directed by Sentinel Lymph Node Biopsy for the Treatment of Oral Cavity Squamous Cell Carcinoma, PRECEDENT Trial
This phase II trial studies how well personalized neck radiation therapy directed by sentinel lymph node biopsy (SLNB) works in treating patients with oral cavity squamous cell carcinoma (OCSCC).
- Conditions
- Oral Cavity Squamous Cell Carcinoma, Stage I Lip and Oral Cavity Cancer AJCC v8, Stage II Lip and Oral Cavity Cancer AJCC v8, Stage III Lip and Oral Cavity Cancer AJCC v8
- Trial name
- NCT07121595
- Testing
- Biospecimen Collection, Carboplatin, Cisplatin
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Michigan Rogel Cancer Center
Locally Advanced Rectal Carcinoma
Modulated Electro-Hyperthermia in Combination With Multimodal Therapy for Locally Advanced Rectal Cancer
The goal of this clinical trial is to investigate if the addition of modulated electro-hyperthermia (mEHT) improves tumor down-staging and pathological response in adult patients (20 years and above) with locally advanced rectal…
- Trial name
- mEHT (NCT07372300)
- Testing
- Hyperthermia
- Where
- Taiwan
- Volunteers
- 126 people
- Sponsor
- Shih-Kai Hung
Biliary Tract Cancer, Cholangiocarcinoma
Chemoimmunotherapy Combined With Hyperthermia and Spatially-Fractionated Radiotherapy in Advanced Biliary Tract Cancer
This study is being done to see if the investigators can improve the outcome of patients with biliary tract cancer that do not qualify for surgery.
- Trial name
- NCT06546969
- Testing
- Gemcitabine, Cisplatin, Durvalumab
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- University of Maryland, Baltimore
Breast Cancer
Hypofractionated Irradiation At Regional Nodal Area for Breast Cancer Vs Existed Standard Treatment
The main objective of this trial is to investigate the efficacy and safety of hypofractionated radiotherapy of 3 or 4 weeks by comparing with conventional radiotherapy of 5 or 6 weeks using intensity-modulated radiation therapy…
- Trial name
- HARVEST (NCT03829553)
- Testing
- Hypofractionated radiotherapy, Conventional radiotherapy
- Where
- China
- Volunteers
- 801 people
- Sponsor
- Ruijin Hospital
Prostatic Cancer
High-dose Brachytherapy Boost With Stereostatic Body Radiation Therapy to Intermediate or Higher Risk Prostate Cancer
The objective of this phase I/II trial is to prospectively evaluate the toxicity and therapeutic efficacy of Stereostatic Body Radiation Therapy (SBRT) to prostate and pelvic lymph nodes in combination with high-dose-rate (HDR)…
- Trial name
- NCT05754580
- Testing
- High Dose Brachytherapy, Stereostatic Body Radiation Therapy
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- University of Nebraska
Arthritis, Arthropathy
Radiation to Treat Joint Damage Caused by Cancer Immunotherapy
This study will prospectively investigate the feasibility and safety of administering LDRT in patients with immunotherapy-induced inflammatory arthritis.
- Trial name
- NCT07478679
- Testing
- Low dose radiation therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Chicago
Cancer
Iparomlimab and Tuvonralimab Combined With SFRT and Definitive Chemoradiotherapy in Locoregionally Advanced Bulky HNSCC
Study Objectives 1. Primary Objective: The core aim of this study is to investigate whether the sequential approach of Spatially Fractionated Radiotherapy followed by 3 cycles of induction chemotherapy combined with Iparomlimab…
- Trial name
- NCT07041788
- Testing
- Iparomlimab and Tuvonralimab Injection
- Where
- China
- Volunteers
- 25 people
- Sponsor
- Second Affiliated Hospital of Nanchang University
Heart Failure, Cardiotoxicity
The STOP-MED CTRCD Trial
Cancer therapy-related cardiac dysfunction (CTRCD) is when the heart's ability to pump oxygenated blood to the body is compromised. It is a side effect of cancer therapy which can occur as commonly as in 1 in 5 patients.
- Conditions
- Heart Failure, Cardiotoxicity, Cardiac Toxicity, Antineoplastics Toxicity
- Trial name
- STOP-MED CTRCD (NCT06183437)
- Testing
- Stopping Heart Failure Medication(s)
- Where
- 14 sites in United States, Australia and 4 more
- Volunteers
- 335 people
- Sponsor
- Dinesh Thavendiranathan
Lung Cancer
The Regression Pattern of Primary Lesions in Lung Cancer After Definitive Radiotherapy
Definitive radiotherapy is one of the important methods for inoperable locally advanced lung cancer. The recommended dose for definitive radiotherapy is 60-70Gy, and the optimal dose is still uncertain.
- Trial name
- NCT06692972
- Where
- 2 sites in China
- Volunteers
- 500 people
- Sponsor
- China-Japan Friendship Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.