Clinical trials: Radiation Injury
Cisplatin Ototoxicity, Hearing Loss
Randomized Trial Comparison of Ototoxicity Monitoring Programs
This study involves research. Some chemotherapeutic drugs that can permanently reduce hearing are termed "ototoxic". One such drug is the chemotherapy called cisplatin.
- Trial name
- COMP-VA (NCT02099786)
- Testing
- COMP-VA, Standard of care
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Elbow Fracture
Radiation Therapy for Heterotopic Ossification Prophylaxis Acutely After Elbow Trauma
The investigators hypothesized that radiation therapy could be safely administered acutely after elbow trauma, and it would decrease the number of patients that would require surgical excision of heterotopic ossification.
- Trial name
- ElbowHO (NCT00991887)
- Testing
- Radiation Therapy (XRT)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Hypertension, Heart Failure
LSFG-SKIN, Laser Speckle Flowgraphy
The purpose of this project is to quantify normal and abnormal skin blood flow regionally in different areas of the body(face, extremities, over burns and wounds) at baseline and over time in response to treatment or…
- Conditions
- Hypertension, Heart Failure, Vascular Ischemia, Burns
- Trial name
- NCT03660618
- Testing
- laser speckle flowgraphy
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Randy Kardon
Radiation Toxicity
Normal Tissue Oxygenation Following Radiotherapy
This study involves women who have had a diagnosis of breast cancer, and have had a lumpectomy with radiation treatments completed in the past year.
- Trial name
- NCT00677040
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Essentia Health
Cardiac Toxicity, Chemotherapeutic Agent Toxicity
Cardiac Magnetic Resonance Imaging in Patients With Non-Hodgkin Lymphoma or Hodgkin Lymphoma Receiving Doxorubicin
RATIONALE: Diagnostic procedures, such as cardiac magnetic resonance imaging, may help doctors detect early changes in the heart caused by chemotherapy.
- Conditions
- Cardiac Toxicity, Chemotherapeutic Agent Toxicity, Lymphoma
- Trial name
- NCT00577798
- Testing
- contrast-enhanced magnetic resonance imaging
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Cardiotoxicity
Staccato Prochlorperazine Thorough QT/QTc
To assess the safety of Staccato Prochlorperazine on cardiac repolarization (QTc interval duration) at 2 dose levels compared to placebo in healthy volunteers.
- Trial name
- NCT00543062
- Testing
- Inhaled prochlorperazine 5 mg, Inhaled prochlorperazine 10 mg, Oral moxifloxacin
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Alexza Pharmaceuticals, Inc.
Radiation Injury
Longitudinal MR Imaging of Pulmonary Function in Patients Receiving Thoracic Radiation Treatment
The purpose of this study is to determine whether magnetic resonance imaging (MRI) using inhaled hyper polarized xenon-129 (129Xe) gas, and conventional contrast can help visualize impaired lung function and detect changes over…
- Trial name
- NCT02478255
- Testing
- Hyperpolarized 129-Xenon gas, MRI
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Bastiaan Driehuys
Acute Radiation Syndrome
BIO 300 Oral Powder Safety and Pharmacokinetics
Open-label, single ascending dose and multiple single dose study in healthy volunteers to evaluate the safety and pharmacokinetics of BIO 300 Oral Powder (BIO 300).
- Trial name
- NCT04650555
- Testing
- BIO 300 Oral Powder
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Humanetics Corporation