Clinical trials: Radiation Mucositis
Radiation-induced Mucositis of Oral Mucous Membranes
Assessing the Preventing and Therapeutic Effect of Propolis in Radiotherapy Induced Mucositis of Head and Neck Cancers
The purpose of this study is to determine whether propolis is effective in the treatment and prevention of radiotherapy induced oral mucositis.
- Trial name
- NCT01375088
- Testing
- propolis
- Where
- Iran
- Volunteers
- 20 people
- Sponsor
- Mashhad University of Medical Sciences
Head and Neck Tumors, Breathomics
Breathomics in the Diagnosis and Prediction of Radiotherapy-Induced Oropharyngeal Mucositis in Head and Neck Tumors
Radiotherapy-Induced Oropharyngeal Mucositis (RIOM) is one of the most distressing side effects for patients with head and neck tumors during radiotherapy, requiring clinical physicians to manage it according to the severity of…
- Conditions
- Head and Neck Tumors, Breathomics, Volatile Organic Compounds, Radiotherapy-induced Oral Mucositis
- Trial name
- NCT06767488
- Where
- China
- Volunteers
- 375 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Head and Neck Cancer
Clinical Study On Acute Radiotherapy-Induced Oral Mucositis In Patients With Locally Advanced Head And Neck Tumors
To explore a more efficient and scientific clinical treatment plan for acute radiotherapy-induced oral mucositis(RIOM/RTOM).it is hoped that the drug combination can more effectively improve the cure rate of acute RIOM,reduce the…
- Trial name
- NCT05364918
- Testing
- Jeksung combined with anti-radiation spray
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Affiliated Cancer Hospital & Institute of Guangzhou Medical University
Radiotherapy Side Effect, Mucositis
Adjunctive Treatments for the Prevention of Radiotherapy-Induced Mucositis
Radiation therapy (RT) is used in at least 50% of cancer patients and is critical in treating and palliating tumor-related symptoms.
- Trial name
- NCT06117904
- Testing
- MEBO ointment, Symptomatic treatment only
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Beni-Suef University
Oral Mucositis (Ulcerative) Due to Radiation
A Prospective Study on the Therapeutic Outcomes of Mebo and Tantum Verde in Patients With Oral Mucositis
This study aimed to assess the efficacy of MEBO® in the treatment of already established oral mucositis. This is a randomized controlled clinical trial.
- Trial name
- NCT07186114
- Testing
- MEBO Wound Ointment (MEBO), Tantum Verde® mouthwash
- Where
- 2 sites in Egypt
- Volunteers
- 36 people
- Sponsor
- Cairo University
Mucositis
Ectoin® Mouth Wash for the Prevention and Treatment of Chemotherapy-induced Oral Mucositis
This is a 3-week, non-interventional, observational study of patients undergoing chemotherapy (sutent) designed as a three-arm parallel study.
- Trial name
- NCT02816515
- Where
- 3 sites in Hungary
- Volunteers
- 46 people
- Sponsor
- Bitop AG
Nasopharyngeal Neoplasms, Stomatitis
Efficacy and Safety of FORRAD® for the Management of Radiation-induced Mucositis in Patients With Nasopharyngeal Carcinoma Receiving IMRT
Radiation therapy remains the principal treatment for nasopharyngeal carcinoma (NPC). The most frequently occurred radiation-related side effect is probably the radiation-induced oral mucositis (OM), which affects up to 100% of…
- Trial name
- NCT02735317
- Testing
- Oral Ulcer Gargle (FORRAD®), Quadruple mixture, composed of dexamethasone, gentamicin, vitamin B12, and procaine
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Yun-fei Xia
Oral Mucositis
N Acetylcystene in Treatment of Radiotherapy Induced Oral Mucositis in Oral Cancer Patients
Background: Radiotherapy appears to be one of the most effective therapies in head and neck tumors, however, there are a lot of complications related to it.
- Trial name
- NCT07082621
- Testing
- N-acetylcysteine (NAC) spray, Conventional treatment
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Hams Hamed Abdelrahman
Mucositis Oral
Omega-3 Hydrogel and Prevention of Oral Mucositis
Oral mucositis (OM) is recognized as one of the most frequent debilitating sequela encountered by head and neck cancer (HNC) patients treated by radiotherapy.
- Trial name
- NCT05214495
- Testing
- topical oral Omega-3 hydrogel, conventional preventive treatment
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Basma Morsy
Oral Mucositis
Effect of Oral Vitamin C in Assessing the Severity of Oral Mucositis in Chemoradiation of Head and Neck Cancers
The surrounding controversies both advocating and simultaneously opposing the use of vitamin C, mostly extrapolating animal models to human models, it has not been used individually to assess the severity of oral mucositis during…
- Trial name
- NCT02868151
- Testing
- Ascorbic Acid, Zinc acetate
- Where
- India
- Volunteers
- 180 people
- Sponsor
- Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre
Head-and-neck Squamous Cell Carcinoma, Oral Mucositis
Role of SAMITAL® in the Relief of Chemo-radiation (CT-RT) Induced Oral Mucositis in Head and Neck Cancer Patients
The purpose of this study is to: evaluate the activity of SAMITAL in reducing the incidence of severe mucositis in head-and-neck cancer patients undergoing chemo-radiotherapy.
- Trial name
- ROSAM (NCT01941992)
- Testing
- SAMITAL®
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Istituto Oncologico Veneto IRCCS
Oral Mucositis (Ulcerative), Oral Mucositis (Ulcerative) Due to Antineoplastic Therapy
Multicentre Real-life Data Collection Study With CareMin650™ in the Prevention and Treatment of Oral Mucositis and Radio- and/or Chemo-induced Dermatitis
Most patients with cancer or haematological malignancies who receive chemotherapy - broadly defined to include targeted therapies and immunotherapy - and/or external beam radiotherapy may experience serious and disabling adverse…
- Conditions
- Oral Mucositis (Ulcerative), Oral Mucositis (Ulcerative) Due to Antineoplastic Therapy, Oral Mucositis (Ulcerative) Due to Radiation, Dermatitis
- Trial name
- NéoPBM (NCT07054528)
- Where
- France
- Volunteers
- 33,000 people
- Sponsor
- Centre Hospitalier de Valenciennes
Oropharyngeal Cancer, Squamous Cell Carcinoma to the Head and Neck
A Pilot Study at a Single-Institution of Pregabalin in the Management of Mucositis Pain in Patients Undergoing Chemoradiation Therapy to the Head and Neck.
To assess the efficacy of pregabalin in the management of mucositis pain in patients receiving radiotherapy to the head and neck.
- Trial name
- NCT02277548
- Testing
- Lyrica 300 mg
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Oral Mucositis
Laser Therapy Versus Ozone Therapy for Oral Mucositis in Patients With Cancer
This retrospective observational study will compare laser therapy and ozone therapy for the management of oral mucositis in adults with head and neck cancer.
- Trial name
- LOMUC-RETRO (NCT07724444)
- Testing
- Laser Therapy, Ozone therapy
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Pavia
Oral Mucositis, Microbiota
Microbiota and Symptom Distress in Head and Neck Cancer Patients Receiving Radiotherapy
The investigators plan to conduct a 3-year pioneering care research project for mucositis in cancer patients. These include: (1) an analysis of the incidence and severity of mucositis, severity, treatment methods, and treatment…
- Conditions
- Oral Mucositis, Microbiota, Symptoms and Signs
- Trial name
- NCT04843644
- Testing
- honey, propolis, Control
- Volunteers
- 250 people
- Sponsor
- Taipei Medical University
Oral Mucositis
Cobiprostone for the Prevention of Oral Mucositis in Subjects With Head and Neck Cancer Receiving Concurrent Radiation and Chemotherapy
Treatment for head and neck cancer often involves a combination of chemotherapy and radiation. One of the unfortunate consequences of standard care for head and neck cancer is the development of painful mouth sores, known as oral…
- Trial name
- NCT02542215
- Testing
- Cobiprostone, Standard Care - Chemotherapy, Standard Care - Radiation
- Where
- 76 sites in United States
- Volunteers
- 47 people
- Sponsor
- Sucampo Pharma Americas, LLC
Mucositis Oral
Treatment of Chemotherapy and Radiotherapy Induced Oral Mucositis
Oral mucositis consequences can range from pain, decreased oral intake, impaired speech and swallowing to adverse events as severe as septicemia, increased hospitalization, and G-tube feeding A wide variety of agents have been…
- Trial name
- NCT04303312
- Testing
- Benzydamine Hydrochloride, Solcoseryl and pumpkin seed oil
- Volunteers
- 54 people
- Sponsor
- Ghada zaki
Oral Mucositis
A Trial of a Botanical Drug Containing East Indian Sandalwood Oil (EISO) for the Treatment of Oral Mucositis
The initial proposed clinical study will be conducted in adult head and neck cancer subjects. This will be an open-labeled, proof of concept trial to evaluate the efficacy, safety and tolerability of EISO in a form of oral rinse…
- Trial name
- NCT02399228
- Testing
- 0.25% EISO mouth rinse
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Santalis Pharmaceuticals, Inc.
Radiation Induced Oral Mucositis, Oral Mucositis
Effect of Arginine- and Glutamine-based Oral Formulations on Salivary Biomarkers and Clinical Severity of Radiation-induced Oral Mucositis in Head and Neck Cancer: A Randomized Controlled Trial
This triple-blinded, randomized controlled clinical trial investigates the effectiveness of L-arginine and L-glutamine oral suspensions in managing radiation-induced oral mucositis (RIOM) in patients with head and neck cancer…
- Conditions
- Radiation Induced Oral Mucositis, Oral Mucositis, Oral Mucositis Due to Radiation
- Trial name
- NCT07020754
- Testing
- L-arginine Oral Suspension, L-glutamine Oral Suspension, Maltodextrin Oral Suspension (Control)
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Ain Shams University
Head and Neck Cancer, Mucositis
Oral Glutamine and Mucositis of Head and Neck Cancer Patients Undergoing Radiation
This study will enroll 60 consecutive patients who are scheduled to receive radiotherapy with/without chemotherapy due to head and neck cancers. Basic data will be recorded along with tumor related variables.
- Trial name
- NCT02282839
- Testing
- Glutamine
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Taichung Veterans General Hospital