Clinical trials: Radio-frequency Ablation
Atrial Fibrillation
RF Ablation of Atrial Fibrillation
This is an early feasibility trial designed to demonstrate whether a new ablation device can be used safely and effectively in treating atrial fibrillation.
- Trial name
- NCT00265629
- Testing
- RF catheter ablation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- C. R. Bard
Carcinoma, Hepatocellular
Anti-PD-1therapy Combined With Thermal Ablation for Advanced HCC
The inhibition of programmed cell death protein 1 (PD-1) has shown promising antitumor activity in advanced hepatocellular carcinoma (HCC). Unfortunately, less than 20% of HCC have response.
- Trial name
- NCT03939975
- Testing
- pembrolizumab or nivolumab or JS001
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Sun Yat-sen University
Atrial Fibrillation, Atrial Fibrillation Paroxysmal
Intensive Molecular and Electropathological Characterization of Patients Undergoing Atrial Fibrillation Ablation
Rationale: Although there are several individual factors which are known to influence the chances of successful atrial fibrillation (AF) ablation, it remains a challenge to identify patients at risk for ablation failure with…
- Conditions
- Atrial Fibrillation, Atrial Fibrillation Paroxysmal, Atrial Fibrillation, Persistent
- Trial name
- ISOLATION (NCT04342312)
- Testing
- Pulmonary vein isolation
- Where
- 2 sites in Netherlands
- Volunteers
- 500 people
- Sponsor
- Maastricht University
Knee Osteoarthritis (OA), Genicular Nerves Block
The Effect of Pulsed Radiofrequency Ablation of the Genicular Nerve on Pain, Balance, and Proprioception in Patients With Chronic Knee Osteoarthritis
Determination of the effect of ultrasound-guided pulsed radiofrequency applied to the genicular nerve on pain, balance, and proprioception in patients with chronic knee osteoarthritis
- Conditions
- Knee Osteoarthritis (OA), Genicular Nerves Block, Radiofrequency Ablation
- Trial name
- NCT07869771
- Testing
- Genicular nerve block via radiofrequency ablation
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Ankara City Hospital Bilkent
Liver Cancer, Bile Duct Cancer
Intra-luminal Radiofrequency Ablation for Inoperable Malignant Biliary Stenosis
Only a small proportion of patients with biliary obstruction caused by hepatopancreatobiliary malignancies are suitable for surgical resection.
- Conditions
- Liver Cancer, Bile Duct Cancer, Pancreatic Cancer
- Trial name
- NCT02841800
- Testing
- 'Intra-luminal radiofrequency ablation (Habib EndoHPB)
- Volunteers
- 5 people
- Sponsor
- National Taiwan University Hospital
Pancreatic Insulinoma
EUS-RFA Versus Surgery for Pancreatic Insulinoma (ERASIN-RCT)
The goal of this muticentre randomized controlled trial is to compare endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) with surgery for treatment of pancreatic insulinoma.
- Trial name
- ERASIN-RCT (NCT05735912)
- Testing
- Endoscopic ultrasound-guided radio frequency ablation, Surgery
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Persistent Atrial Fibrillation
Effect of Catheter Ablation on Left Atrial Function in Persistent Atrial Fibrillation
A total of 106 patients with drug-refractory persistent atrial fibrillation, who are planned to undergo circumferential pulmonary vein isolation (CPVI), will be randomly allocated into two groups.
- Trial name
- NCT03443232
- Testing
- Cryoballoon ablation, Radiofrequency ablation
- Where
- China
- Volunteers
- 106 people
- Sponsor
- The Second Hospital of Hebei Medical University
Carcinoma, Renal Cell
Palliative Radiofrequency Ablation in Metastatic Renal Cell Carcinoma Patients
The purpose of this study is to evaluate efficacy and safety of Radiofrequency ablation in metastatic renal cell carcinoma patients with primary tumor less than 5 cm before medical treatment.
- Trial name
- NCT00891475
- Testing
- Radiofrequency ablation; Interferon-alpha, Radiofrequency ablation; Sunitinib maleate, Sunitinib maleate
- Where
- Russia
- Volunteers
- 114 people
- Sponsor
- Kidney Cancer Research Bureau
Metastatic Lesions in Vertebral Bodies
Evaluating Clinical Outcomes of Targeted Radiofrequency Ablation and Kyphoplasty (Also Known as Vertebral Augmentation) to Treat Painful Metastatic Vertebral Body Tumors
To evaluate the clinical outcomes of minimally invasive targeted radiofrequency tumor ablation (t-RFA) and kyphoplasty (also known as vertebral augmentation) in painful metastatic lesions in the spine.
- Trial name
- EU-STAR (NCT02081053)
- Testing
- STAR™ Tumor Ablation System and StabiliT® Vertebral Augmentation System
- Where
- 8 sites in France, Germany and 1 more
- Volunteers
- 30 people
- Sponsor
- DFINE Inc.
Bile Duct Cancer
Safety of Biliary Intraductal Radiofrequency Ablation in Patients With Unresectable Extrahepatic Biliary Tract Cancer
The goal of this clinical trial is to provide evidence for the general tolerability of radiofrequency ablation (bRFA) in patients with unresectable bile duct cancer undergoing systemic palliative treatment consisting of systemic…
- Trial name
- Ablatio (NCT06274879)
- Testing
- Gemcitabin, Cisplatin and Durvalumab, Biliary Radiofrequency Ablation, Endoscopic Retrograde Cholangio-Pancreatography with stenting
- Where
- 4 sites in Switzerland
- Volunteers
- 36 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Intractable Allergic Rhinitis
Posterior Nasal Nerve Neurectomy for Treatment of Intractable Allergic Rhinitis
This study aims to compare the outcomes of posterior nasal nerve neurectomy in patients with resistant Allergic rhinitis by using three different methods ( surgical resection vs radiofrequency ablation vs surface coblation )…
- Trial name
- NCT06887842
- Testing
- Posterior Nasal Nerve neurectomy
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Kafrelsheikh University
Liver Carcinoma
Hepatocellular Carcinoma Treated With Iodine-125 Implantation
To prospectively evaluate whether use of combined radiofrequency ablation (RFA) and percutaneous iodine-125 (125I) seeds implantation results in better survival compared with use of RFA alone in patients with hepatocellular…
- Trial name
- NCT01717729
- Testing
- Radiofrequency Ablation, iodine
- Volunteers
- 136 people
- Sponsor
- The Second People's Hospital of GuangDong Province
Atrial Fibrillation
Dual Epicardial Endocardial Persistent Atrial Fibrillation(AF) Study (Staged DEEP)
The purpose of this study is to assess the safety and technical feasibility of treating subjects with Persistent Atrial Fibrillation or Longstanding Persistent Atrial Fibrillation in a minimally invasive thoracoscopic ablation…
- Trial name
- Staged DEEP (NCT01661205)
- Testing
- Ablation procedure staged catheter ablation
- Where
- 6 sites in United States, Belgium and 1 more
- Volunteers
- 30 people
- Sponsor
- AtriCure, Inc.
Renal Cell Carcinoma, Zero Ischemia
Zero Ischemia Laparoscopic Radio Frequency Ablation Assisted Enucleation of Renal Cell Carcinoma With T1a Stage
To evaluate the feasibility and efficiency of zero ischemia laparoscopic radio frequency ablation assisted enucleation of T1a renal cell carcinoma in comparison with the conventional laparoscopic partial nephrectomy.
- Trial name
- NCT01838720
- Testing
- zero ischemia laparoscopic RFA assisted TE, ischemia
- Where
- China
- Volunteers
- 90 people
- Sponsor
- RenJi Hospital
Osteoarthritis of the Knee
Coolief Cooled Radiofrequency vs. Conventional Radiofrequency to Manage OA Knee Pain
This study is being performed to assess the relative effectiveness of genicular nerve ablation with the COOLIEF* Cooled Radiofrequency probe to manage moderate to severe knee pain in patients with osteoarthritis (OA) of the knee…
- Trial name
- NCT04145011
- Testing
- Cooled Radiofrequency, Standard Radiofrequency
- Where
- 7 sites in United States
- Volunteers
- 153 people
- Sponsor
- Avanos Medical
Liver Cancer, Neoplasms, Liver
Study of New Software Used During Ablations
Background: Ablation is a procedure that heats tumor tissue to a high temperature to destroy it. Doctors perform this procedure by putting a probe in the tumor. This delivers heat to the site.
- Conditions
- Liver Cancer, Neoplasms, Liver, Hepatic Neoplasms, Hepatic Cancer
- Trial name
- NCT01906021
- Testing
- CT/CBCT thermometry method, Ablation Probe
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Brugada Syndrome
Epicardial Radiofrequency Catheter Ablation in Patients With Brugada Syndrome
This randomized, sham-controlled, and blinded clinical trial aims to evaluate the effects of radiofrequency catheter ablation on the phenotypic expression of patients with Brugada syndrome.
- Trial name
- NCT05685134
- Testing
- Radiofrequency catheter ablation
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Sao Paulo General Hospital
Hepatocellular Carcinoma
Radiofrequency Ablation for Hepatocellular Carcinoma Using Octopus MP Electrodes
This study is to investigate the therapeutic effect and treatment results of radiofrequency ablation using the Octopus MP electrode capable of temperature monitoring and drug injection and a variable-length electrode for…
- Trial name
- NCT05666271
- Testing
- Radiofrequency ablation
- Where
- South Korea
- Volunteers
- 76 people
- Sponsor
- Seoul National University Hospital
Gonarthrosis
Bipolar Versus Cooled Radiofrequency Ablation for Gonarthrosis
Patients with chronic knee osteoarthritis who do not respond adequately to conservative treatment may benefit from genicular nerve radiofrequency ablation procedures.
- Trial name
- NCT07879664
- Testing
- Bipolar Radiofrequency Ablation, Cooled Radiofrequency Ablation
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Saglik Bilimleri Universitesi
Atrial Fibrillation
The Ablate-by-LAW Study
Of all the determinants of lesion creation during atrial fibrillation (AF) ablation, left atrial wall thickness (LAWT), as measured with multi-detector cardiac tomography (MDCT) is one key element that has been evaluated in some…
- Trial name
- NCT04218604
- Testing
- Personalized atrial fibrillation ablation
- Where
- 5 sites in Germany, Italy and 1 more
- Volunteers
- 106 people
- Sponsor
- Centro Medico Teknon