Clinical trials: Radioactive Seed Implantation
Prostate Cancer
Study Assessing The Efficacy And Safety Of Avodart (Dutasteride) At Improving Urinary Symptoms In Men With Prostate Cancer Who Are Undergoing Seed Implantation
Avodart (dutasteride) reduces the male hormone (DHT) that leads to prostate growth and stimulates cancerous growth. Avodart is currently approved by the FDA to treat men with symptoms of an enlarged prostate.
- Trial name
- NCT00805701
- Testing
- avodart
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Bay State Clinical Trials, Inc.
Hepatocellular Carcinoma, Portal Vein Occlusion
TACE Combined With Iodine-125 Seeds Implantation for HCC
Portal vein tumour thrombus (PVTT) is a common complication of hepatocellular carcinoma (HCC). PVTT has a profound adverse effect on prognosis, with a very short median survival time (2-4 months).
- Conditions
- Hepatocellular Carcinoma, Portal Vein Occlusion, Tumor Thrombus
- Trial name
- NCT03322280
- Testing
- TACE combined with iodine-125 seeds implantation, TACE
- Where
- China
- Volunteers
- 270 people
- Sponsor
- Second Affiliated Hospital of Guangzhou Medical University
Prostate Cancer Patients Undergoing External Radiation and Seed Implantation, High Risk Localised Prostate Carcinoma
Addition of Focal Boost to Primary Radiotherapy for Prostate Cancer in 12 or 20 Fractions
Every year, about 700 Danish men get radiotherapy for prostate cancer with a high-risk of later progression. The risk of relapse is about 40 % after 5 - 8 years, so we need better treatment for these patients in Denmark and…
- Conditions
- Prostate Cancer Patients Undergoing External Radiation and Seed Implantation, High Risk Localised Prostate Carcinoma, Locally Advanced Prostate Cancer, Unfavourable Intermediate Risk Prostate Cancer
- Trial name
- DAPROCA10 (NCT07343349)
- Testing
- Addition of focal boost and hypofractionation
- Where
- 3 sites in Denmark
- Volunteers
- 1,016 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Brachytherapy, Squamous Cell Carcinomas
RISI in the Treatment of Recurrent Metastatic SCC of Thoracic Inlet Lymph Nodes
The malignant tumor at the thoracic entrance is difficult to be surgically removed, and radiotherapy or radiotherapy based comprehensive treatment is often chosen at the initial diagnosis.
- Trial name
- NCT04266327
- Testing
- 3D-printing Template-assisted CT-guided I-125 Seed Implantation
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking University Third Hospital
Accuracy of Coplanar Template Assisted Seed Implantation for Abdominal and Pelvic Cancer
Accuracy of Coplanar Template Assisted Seed Implantation for Abdominal and Pelvic Cancer
In recent years, template guidance has been applied and developed in the field of puncture related operations, such as template-assisted radioactive seed implantation.
- Trial name
- NCT05483452
- Where
- China
- Volunteers
- 34 people
- Sponsor
- Peking University Third Hospital
Breast Neoplasms
A Registry Study of Permanent Breast Seed Implant
Women found to have early stage breast cancer will have their cancer surgically removed followed by radiation treatment to the entire breast, five times per week for several weeks.
- Trial name
- NCT01106521
- Testing
- Permanent breast seeds implant
- Where
- Canada
- Volunteers
- 420 people
- Sponsor
- Sunnybrook Health Sciences Centre
Prostatic Neoplasms, Cancer of the Prostate
Hemi-Ablative Prostate Brachytherapy
This clinical study will evaluate side effects, quality of life and cancer control in patients with prostate cancer diagnosed on only one side of the prostate gland.
- Trial name
- HAPpy (NCT02632669)
- Testing
- Hemigland focal LDR brachytherapy
- Where
- United Kingdom
- Volunteers
- 31 people
- Sponsor
- Royal Surrey County Hospital NHS Foundation Trust
HCC - Hepatocellular Carcinoma, 125I Seeds Implantation
PD-1 Inhibitor Combined With 125I Seed Implantation for Hepatocellular Carcinoma's Extrahepatic Metastasis: Efficacy and Safety
This study aims to explore the effectiveness and safety of 125I seed implantation in the treatment of hepatocellular carcinoma (HCC) with extrahepatic metastases, and to compare the efficacy differences between PD-1 inhibitor…
- Trial name
- NCT06991907
- Testing
- 125I seed implantation, PD-1 Inhibitors
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Jiangxi Provincial Cancer Hospital
Pancreatic Cancer
Iodine-125 Seed Implantation Therapy for Locally Advanced Pancreatic Cancer
This study evaluates the application of 3D-printed template for iodine-125 seed implantation therapy in patients with locally advanced pancreatic cancer.
- Trial name
- NCT03882866
- Testing
- 3D-printed non-coplanar template, 3D-printed coplanar template
- Where
- 8 sites in China
- Volunteers
- 220 people
- Sponsor
- Ruijin Hospital
Prostate Cancer Patients Who Have Brachytherapy Seed Implant
Identifying Prostate Brachytherapy Seeds Using MRI
This study will look at the feasibility of using a type of Magnetic Resonance Imaging called Susceptibility Weighted Imaging (SWI) to detect your implanted radioactive seeds.
- Trial name
- NCT01878058
- Testing
- MRI Scan
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University Health Network, Toronto
Recurrent Rectal Cancer, 125I Seeds Implantation
CTV Exploration of 3D-PT Assisted CT-guided I-125 Seeds Implantation for Recurrent Rectal Cancer
This study is to explore the progression-free survival time (PFS) , overall survival time (OS), quality of life and side effects between two different clinical target volumes in the treatment of 3D printing template-assisted…
- Conditions
- Recurrent Rectal Cancer, 125I Seeds Implantation, Clinical Target Volume
- Trial name
- NCT04710589
- Testing
- CTV
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking University Third Hospital
Malignant Obstructive Jaundice
Comparison of Two Seed Strand Implantation Techniques for Biliary Cancer
This study aimed to compare the safety and effectiveness of two different methods for fabricating and implanting Iodine-125 (^125^I) radioactive seed strands combined with a metal stent for treating malignant obstructive…
- Trial name
- NCT07381439
- Testing
- Percutaneous transhepatic biliary stenting with conventional linear ^125^I seeds strand, Percutaneous transhepatic biliary stenting with novel spiral ^125^I seeds strand
- Where
- China
- Volunteers
- 105 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Hepatocellular Carcinoma, Hepatic Portal Vein Tumor Invasion
Combination Treatment for Advanced Liver Cancer
The purpose of this study is to determine whether TACE combined endovascular stent implantation confers a survival benefit over TACE alone.
- Trial name
- NCT02149771
- Testing
- chemoembolization, endovascular stents implantation, iodine-125 seed strand implantation
- Where
- China
- Sponsor
- Shanghai Zhongshan Hospital
Prostate Cancer
Efficacy of Prostate Seed Implantation for Local Control of Early Stage Prostate Cancer
The primary goal of this project is to evaluate the efficacy of prostate seed implantation for the treatment of early stage prostate cancer for patients treated at Summa Health System/Akron City Hospital and Salem Community…
- Trial name
- NCT00773305
- Volunteers
- 200 people
- Sponsor
- Summa Health System
Prostate Cancer, Post-Brachytherapy Bladder Outlet Obstruction
Prophylactic Urethral Stenting With Memokath After Prostate Implantation for Prostate Adenocarcinoma
The purpose of this study is to determine the feasibility, safety, and efficacy of the Memokath® 028SW stent to prevent urinary obstructive symptoms (difficulty urinating) when used after prostate seed implantation for the…
- Trial name
- NCT00252941
- Testing
- Memokath 028SW Urethral Stent
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The Cleveland Clinic
Pancreatic Cancer Non-resectable, Brachytherapy
I125 Seed Implantation vs Stereotactic Radiotherapy for Pancreatic Cancer
Data of 100 patients with locally advanced pancreatic cancer who received stereotactic radiotherapy or ct-guided radioactive 125I seed implantation in the multicenter of the research group from July 2019 to June 2021 were…
- Conditions
- Pancreatic Cancer Non-resectable, Brachytherapy, Radiotherapy
- Trial name
- Ckvssip (NCT03964064)
- Testing
- Stereotactic Radiotherapy, 3D-printing Template-assisted CT-guided I125 Seed Implantation
- Where
- 4 sites in China
- Volunteers
- 100 people
- Sponsor
- Peking University Third Hospital
Chest Wall Tumor
RISI in the Treatment of Recurrent Chest Wall Malignancies After EBRT
This study will observe the efficacy and toxicities of 3-dimensional printing noncoplanar template assisted CT guided radioactive iodine-125 seeds implantation in the treatment of patients with recurrent chest wall malignancies…
- Trial name
- NCT04077710
- Testing
- Radioactive Iodine-125 Seeds Implantation
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking University Third Hospital
Prostate Cancer, Lower Urinary Tract Symptoms
Botulinum Toxin Injection With Prostate Brachytherapy
The purpose of this study is to see if botox injection into the prostate during seed implantation (brachytherapy) for prostate cancer a) improves urinary symptoms or avoids need for urinary tract instrumentation over the 6-8…
- Conditions
- Prostate Cancer, Lower Urinary Tract Symptoms, Radioactive Seed Implantation
- Trial name
- NCT00681148
- Testing
- Botox injection, Saline injection
- Where
- United States
- Sponsor
- Emory University
Brachytherapy, Desmoid Tumor
CT-guided Radioactive Iodine-125 Seed Implantation for Recurrent Desmoid Tumors
This study aimed to explore the long-term outcomes of CT-guided radioactive iodine-125 (I-125) seed implantation (RISI) for recurrent desmoid tumor.
- Conditions
- Brachytherapy, Desmoid Tumor, Radioactive Iodine-125 Seed Implantation
- Trial name
- NCT06195085
- Testing
- CT-guided radioactive iodine-125 seed implantation
- Where
- China
- Volunteers
- 38 people
- Sponsor
- Peking University Third Hospital
Radioactive Iodine-125 Brachytherapy, Thoracic Cancer
3DPCT Combined With CT Guided RISI in the Treatment of Thoracic Malignant Tumors
The main technical difficulties in radioactive iodine-125 seed implantation (RISI) lie in the complexity of operation and the control of operation quality.
- Conditions
- Radioactive Iodine-125 Brachytherapy, Thoracic Cancer, 3D Printing Coplanar Template, Nuclear Radiation Effects
- Trial name
- NCT05351268
- Testing
- Radioactive seed brachytherapy
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking University Third Hospital