Clinical trials: Radiofrequency Ablation, open to volunteers
Bipolar Radiofrequency Ablation, Unipolar Radiofrequency Ablation
Unipolar Versus Bipolar Radiofrequency Ablation in Knee Osteoarthritis Pain
This study aims to compare the efficacy of unipolar versus bipolar radiofrequency ablation (RFA) in knee osteoarthritis pain.
- Conditions
- Bipolar Radiofrequency Ablation, Unipolar Radiofrequency Ablation, Knee Osteoarthritis, Pain
- Trial name
- NCT07789340
- Testing
- Unipolar radiofrequency ablation, Bipolar radiofrequency ablation
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Tanta University
Catheter Ablation, Radiofrequency
Early Ambulation Safety Evaluation, Ultrasound-guided Percutaneous Venous Closure
The purpose of this study is to evaluate whether patients can safely walk sooner after catheter-based heart procedures when the VASCADE MVP or VASCADE MVP XL vascular closure device is used.
- Trial name
- NCT07910227
- Testing
- VASCADE MVP and MVP XL
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Pennsylvania
Dysplastic Barrett's Esophagus, Radiofrequency Ablation
Impact of RFA on Esophageal Distensibility and Mucosal Impedance
Patients undergoing ablative therapy for management of dysplastic Barrett's Esophagus (BE) will have decreased distensibility over the course of treatment, but improvement in mucosal impedance as BE epithelia is replaced by…
- Conditions
- Dysplastic Barrett's Esophagus, Radiofrequency Ablation, Barrett Esophagus
- Trial name
- NCT07126535
- Testing
- Radiofrequency ablation alone
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Mayo Clinic
Cryoneurolysis, Bipolar Radiofrequency Ablation
Cryoneurolysis Versus Bipolar Radiofrequency Ablation of Genicular Nerves for Pain Relief in Symptomatic Knee Osteoarthritis
This study aims to compare the reduction in knee pain between ultrasound-guided cryoneurolysis and bipolar radiofrequency ablation (RFA), as measured by the Numerical Rating Scale (NRS) at predefined follow-up intervals.
- Conditions
- Cryoneurolysis, Bipolar Radiofrequency Ablation, Genicular Nerves, Pain Relief
- Trial name
- NCT07855367
- Testing
- Ultrasound-guided cryoneurolysis, Bipolar radiofrequency ablation
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- National Cancer Institute, Egypt
Low Risk, Papillary Thyroid Cancer
Radiofrequency Ablation for Management of Benign/Indeterminate Thyroid Nodules and Low Risk Papillary Thyroid Cancers
To track the outcomes of patients who have been treated with RFA and its long-term effectiveness, and to learn more about the quality of life of patients who have received RFA in this study.
- Conditions
- Low Risk, Papillary Thyroid Cancer, Radiofrequency Ablation
- Trial name
- NCT07140757
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- M.D. Anderson Cancer Center
Atrial Fibrillation, Catheter Ablation
Randomized Controlled Trial- Ablation Strategy for Paroxysmal Atrial Fibrillation - Trigger and Substrate Guided Wide Area Radiofrequency Ablation Compared to Pulsed Field Ablation Pulmonary Vein Isolation
Atrial fibrillation (AF) is a common heart rhythm disorder affecting over a million people in North America and is associated with serious complications including stroke, heart failure, reduced quality of life, and premature…
- Conditions
- Atrial Fibrillation, Catheter Ablation, Radiofrequency Catheter Ablation
- Trial name
- AWARE-2 (NCT04823299)
- Testing
- PVI-ONLY, CONTROL ARM, PVI-PLUS ARM, INTERVENTIONAL ARM
- Where
- 2 sites in Canada
- Volunteers
- 556 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Primary Aldosteronism Due to Conn Adenoma, Radiofrequency Ablation Treatment
Radiofrequency Ablation Versus Adrenalectomy for Adenoma in Patients With Primary Aldosteronism and Hypertension
Primary aldosteronism (PA) is characterized by hypertension, frequent hypokalaemia, and an inappropriately high aldosterone-to-renin ratio (ARR).
- Conditions
- Primary Aldosteronism Due to Conn Adenoma, Radiofrequency Ablation Treatment, Adrenalectomy
- Trial name
- ADERADHTA2 (NCT07470580)
- Testing
- RFA -radiofrequency ablation, Adrenalectomy
- Where
- France
- Volunteers
- 134 people
- Sponsor
- University Hospital, Toulouse
Atrial Fibrillation (AF), Atrial Fibrillation Ablation
Pulsed Field Ablation Outcomes With Efficacy and Randomization in Atrial Fibrillation (POWER-AF)
Atrial fibrillation (AF) is one of the most common arrhythmias in clinical practice. As of 2019, there were approximately 59.7 million patients with AF worldwide, including atrial flutter (AF).
- Conditions
- Atrial Fibrillation (AF), Atrial Fibrillation Ablation, Atrial Fibrillation Recurrent, Pulsed Field Ablation
- Trial name
- POWER-AF (NCT07601763)
- Testing
- Pulsed field ablation, Radiofrequency ablation alone, Pulsed field ablation system
- Where
- China
- Volunteers
- 1,574 people
- Sponsor
- China National Center for Cardiovascular Diseases
Endoscopic Ultrasound-Guided Radiofrequency Ablation, Pancreatic Neuroendocrine Tumors (pNET)
Endoscopic Ultrasound-Guided Radiofrequency Ablation for Pancreatic Cystic Neoplasms and Pancreatic Neuroendocrine Tumors
The primary aim of this study is to evaluate the technical feasibility and effectiveness of endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) in the treatment of pancreatic cystic neoplasms (PCNs) and pancreatic…
- Conditions
- Endoscopic Ultrasound-Guided Radiofrequency Ablation, Pancreatic Neuroendocrine Tumors (pNET), Pancreatic Cystic Neoplasms
- Trial name
- NCT07536087
- Testing
- Endoscopic ultrasound-guided radiofrequency ablation for pancreatic cystic lesions, Endoscopic ultrasound-guided radiofrequency ablation of pancreatic solid lesions
- Where
- Czechia
- Volunteers
- 50 people
- Sponsor
- Institute for Clinical and Experimental Medicine
Knee Osteoarthristis, Radiofrequency Ablation
Knee Osteoartritis Genicular Nerve RF Ablation vs Alcohol Neurolysis
The GEN-AL-RF study is a randomized controlled trial designed to compare the clinical efficacy of two interventional techniques for managing chronic knee pain due to osteoarthritis.
- Conditions
- Knee Osteoarthristis, Radiofrequency Ablation, NEUROLYSIS
- Trial name
- GEN-AL-RF (NCT07537335)
- Testing
- genicular nerve block
- Volunteers
- 50 people
- Sponsor
- Sakarya University
Bone Cancer Metastatic, Radiofrequency Ablation
Effectiveness Of Radiofrequency Ablation And Stabilization In Metastatic Spine Lesions By Positron Emission Computed Tomography (PET-CT) Confirmation
This pilot study will try to demonstrate metabolic changes in spine lesions treated by Augmentation and Ablation, according to existing standards of practice.
- Conditions
- Bone Cancer Metastatic, Radiofrequency Ablation, Spine Metastases, Vertebral Metastasis
- Trial name
- ABLASPINE (NCT06716294)
- Testing
- Radiofrequency Ablation and Bone Augmentation
- Where
- Greece
- Volunteers
- 16 people
- Sponsor
- National and Kapodistrian University of Athens
Insulinoma; Pancreas, MEN1
Endoscopic Ultrasound-guided Radiofrequency Ablation for Upper Gastrointestinal Tract Lesions
The goal of this observational study is to evaluate the long-term clinical effectiveness of EUS-RFA and quality of life in patients with pancreatic or adrenal tumors recieving EUS-RFA.
- Conditions
- Insulinoma; Pancreas, MEN1, NETs, Radiofrequency Ablation
- Trial name
- EURAGIL (NCT07272187)
- Testing
- observational study
- Where
- Denmark
- Volunteers
- 138 people
- Sponsor
- Herlev Hospital
Chronic Venous Insufficiency, CVI, Radiofrequency Ablation
Risks and Benefits of Radiofrequency Ablation for Chronic Venous Insufficiency (CEAP C3-C6) in Patients Aged 80 and Over
The prevalence of severe chronic venous insufficiency (CVI) is significant in the growing octogenarian population. While radiofrequency ablation (RFA) is a standard minimally invasive treatment, robust data on its outcomes and…
- Conditions
- Chronic Venous Insufficiency, CVI, Radiofrequency Ablation, Octogenarians(Aged 80 and Over), Cohort Study
- Trial name
- NCT07233616
- Testing
- Endovenous Radiofrequency Ablation
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Chengdu University of Traditional Chinese Medicine
Oral Antiplatele, Anticoagulant Drugs
Effect of Oral Antiplatelet or Anticoagulant Drugs on Postoperative Bleeding Risk and Venous Closure Rate in Patients With Lower Extremity Varicose Veins After Radiofrequency Ablation
This observational study aims to assess the effect of oral antiplatelet or anticoagulant drugs on key postoperative outcomes in patients with lower extremity varicose veins who have undergone radiofrequency ablation.
- Conditions
- Oral Antiplatele, Anticoagulant Drugs, Lower Extremity Varicose Veins, Radiofrequency Ablation
- Trial name
- NCT07208695
- Testing
- Antiplatelet or Anticoagulant Drugs
- Volunteers
- 40 people
- Sponsor
- Chengdu University of Traditional Chinese Medicine
Atrial Fibrillation (AF), Ablation Techniques
Electroporation vs. Radiofrequency Ablation Guided by 3D Imaging in Repeat Procedures for Atrial Fibrillation
This is a prospective, randomized clinical trial evaluating the efficacy and safety of two techniques for repeat catheter ablation in patients with recurrent atrial fibrillation (AF): thermal energy ablation (radiofrequency) and…
- Conditions
- Atrial Fibrillation (AF), Ablation Techniques, Radiofrequency Catheter Ablation, Pulsed Field Ablation
- Trial name
- ERA-rePVI (NCT07141745)
- Testing
- Pulsed field ablation of reccurent atrial arrythmia, Radiofrequency ablation of reccurent atrial arrythmia (standard of care)
- Where
- Poland
- Volunteers
- 250 people
- Sponsor
- Wroclaw Medical University
Plantar Fasciopathy, Chronic Pain
One Cause of Heel Pain is Plantar Fasciopathy (PF). In Most Cases, a Heel Spur is Frequently Present Alongside PF. We Aim to Evaluate the Efficacy of Corticosteroid Injection and Radiofrequency Ablation, Along With Tissue Elasticity Assessed by Ultrasound, in Patients With Chronic Pain (≥6 Months).
Heel pain is common among adults. One cause of heel pain is plantar fasciopathy (PF). In most cases, a heel spur, a bony prominence that extends into the plantar fascia, is frequently present alongside PF.
- Conditions
- Plantar Fasciopathy, Chronic Pain, Corticosteroid Injection, Radiofrequency Ablation
- Trial name
- NCT07120204
- Testing
- Corticosteroid Injection, Radiofrequency thermocoagulation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- TC Erciyes University
Obstructive Hypertrophic Cardiomyopathy, Mavacamten
Efficacy of Mavacamten Combined With Radiofrequency Ablation in Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy
This study aims to evaluate the efficacy and safety of Mavacamten combined with radiofrequency ablation compared to Mavacamten alone in patients with symptomatic obstructive hypertrophic cardiomyopathy (HOCM).
- Conditions
- Obstructive Hypertrophic Cardiomyopathy, Mavacamten, Radiofrequency Ablation
- Trial name
- NCT06856265
- Testing
- radiofrequency ablation, Mavacamten
- Volunteers
- 40 people
- Sponsor
- Shanghai Chest Hospital
Persistent Atrial Fibrillation, Radiofrequency Catheter Ablation
Pulsed Field Ablation Versus Radiofrequency Ablation for Persistent Atrial Fibrillation
This clinical trial aims to compare the efficacy and safety of pulsed field ablation and radiofrequency ablation to treat persistent atrial fibrillation in adults.
- Conditions
- Persistent Atrial Fibrillation, Radiofrequency Catheter Ablation, Pulsed Field Ablation
- Trial name
- PRAISE (NCT06791629)
- Testing
- Pulsed Field Ablation, Radiofrequency Ablation
- Where
- China
- Volunteers
- 700 people
- Sponsor
- Beijing Anzhen Hospital
Radiofrequency Ablation, Atrial Fibrillation
Effect of Mechanical Ventilation on Radiofrequency Ablation in Atrial Fibrillation
Radiofrequency ablation (RFA) for atrial fibrillation (AF) is performed under general anesthesia. The success of the procedure depends on the safe contact of the catheter electrode with the myocardium.
- Conditions
- Radiofrequency Ablation, Atrial Fibrillation, Mechanical Ventilation
- Trial name
- NCT06791915
- Testing
- Radiofrequency Ablation with FCV., Radiofrequency Ablation with VCV.
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Kocaeli City Hospital
Hepatocellular Carcinoma (HCC), Radiofrequency Ablation
Ga-68 Dolacga PET Scan in HCC Under RFA
This study aims to investigate the use of Ga-68 Dolacga PET scan technology to assess treatment response and liver function changes in patients of early-stage liver cancer receiving RFA.
- Conditions
- Hepatocellular Carcinoma (HCC), Radiofrequency Ablation, PET Scan, Computed Tomography
- Trial name
- HCC; RFA (NCT06792097)
- Testing
- Ga-68 Dolacga PET scan
- Volunteers
- 10 people
- Sponsor
- National Taiwan University Hospital