Clinical trials: Radiology, Interventional
Cardiovascular Diseases
Evaluation of Exposure Reduction Using Region-of-Interest Fluoroscopy (X-ray Fovea Imaging) in Cardiac Interventions
The aim of the proposed study is to compare the exposure dose and diagnostic performance of region-of-interest fluoroscopy compared to standard fluoroscopy in patients and interventionists during cardiac interventional…
- Trial name
- NCT00817115
- Testing
- Region-of-Interest Imaging (X-ray Fovea Imaging)
- Where
- Canada
- Volunteers
- 75 people
- Sponsor
- Sunnybrook Health Sciences Centre
Bone Cysts
Aneurysmal Bone Cyst Imaging After Interventional Radiology Treatment
This study aims to describe the clinical outcomeand the radiological appearance of aneurysmal bone cyst treated by means of interventional radiology procedures (percutaneous sclerosis and endovascular embolization)
- Trial name
- KOA-RI (NCT05075148)
- Testing
- radiology
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Montpellier
Radiology, Interventional, Heart Rhythm Disorders
Dosimetric Reference Levels for Radioguided Interventional Procedures in Rhythmology.
Interventional radiology has become a widespread technique used in various fields of medicine to diagnose or treat numerous pathologies. However, the risk of X-rays must be taken into account.
- Trial name
- NR-Rythmo (NCT06507085)
- Testing
- Radio-guided interventions to correct heart rhythm disorders
- Where
- France
- Volunteers
- 4,219 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Tissular Lesion
Interest in Using Ultrasound Fusion in Percutaneous Interventional Radiology
The investigators want to evaluate the accuracy of an ultrasound fusion guiding system in the positioning of a needle (here the accuracy is evaluated with a 22G spinal needle), by comparing the path indicated by the ultrasound…
- Trial name
- ECHOFUSION (NCT02563444)
- Testing
- Ultrasound fusion guiding system - TUS A-500 (Aplio 500)
- Where
- France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Strasbourg, France
Refractory Malignant Ascites
Palliative Care Outcomes in the Management of Malignant Ascites by Interventional Radiology
Malignant ascites leads to significant morbidity in patients with terminal cancer. Paracentesis can provide relief, but repeat hospital visits, pain, and short duration of relief after paracentesis are detrimental to quality of…
- Trial name
- NCT02477657
- Testing
- Paracentesis, Tunneled Intraperitoneal Drain (IPD), Peritoneal-Venous shunts (PVS)
- Where
- United States
- Sponsor
- Abramson Cancer Center at Penn Medicine
Hepatocellular Carcinoma
Immunomonitoring of Interventional Radiology Procedures in the Management of Hepatocellular Carcinoma
This cohort study compares immune response induced in two groups of small HCC patients treated by ablation (group1 RFA, group 2 MWA).
- Trial name
- PAI²HCC (NCT04892810)
- Testing
- Percutaneous ablation
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Grenoble
Grade III Traumatic Splenic Injury in Hemodynamically Stable Patients
Traumatic Injury of Spleen:Laparoscopic Splenectomy Vs Splenic Artery Embolization
The goal of this clinical trial is selection of the best method in management of grade 3 traumatic Splenic Injury in Hemodynamically Stable Patients thus improving the quality of life and clinical outcome.
- Trial name
- NCT07274007
- Testing
- Laparoscopic Splenectomy vs splenic Artery Embolization
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Lung Cancer, Surgery
Neoadjuvant Intra-tumor Double Immunotherapy for Lung Cancer.
This phase II trial studies how well intra-tumor injection of double checkpoint inhibitors work when given alone and in combination with chemotherapy or/and bevacizumab in treating patients with previously untreated stage I-IIIA…
- Conditions
- Lung Cancer, Surgery, Non-small Cell Lung Cancer
- Trial name
- NCT06492421
- Testing
- ipilimumab, pembrolizumab, durvalumab, idarubicin, bevacizumab
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Second Affiliated Hospital of Guangzhou Medical University
Breast Cancer, Interventional Radiology
Using Color Doppler US Artifact to Identify Tumor Markers
Before neoadjuvant chemotherapy (NACT) in cases of locally advanced breast cancer, malignant masses in the breast and biopsy-proven tumor involvement axillary lymph nodes are marked with metallic markers.
- Conditions
- Breast Cancer, Interventional Radiology, Doppler Ultrasound
- Trial name
- NCT06166173
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Medeniyet University
Pain, Analgesia
Thermomechanical Distraction and Social Anesthesia in Interventional Radiology to Improve Patient Satisfaction
The study will prospectively analyze the analgesic and anxiolytic effects of thermomechanical stimulation (cold and vibration effects) with or without patient selected music preference during non-sedating interventional radiology…
- Conditions
- Pain, Analgesia, Anxiety
- Trial name
- NCT04236674
- Testing
- Buzzy thermomechanical device, Music Selection
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Temple University
Surgery, Anesthesiology
Reducing Low-Value Preoperative Investigations in Patients Undergoing Low Risk Surgery
The purpose of this study is to evaluate if a multi-component behavioral intervention given to anesthesiologists and surgeons is associated with decreasing low value preoperative testing orders in patients undergoing low risk…
- Trial name
- Pre-Op (NCT05526495)
- Testing
- Reducing preoperative low-value test ordering
- Where
- 4 sites in Canada
- Volunteers
- 22 people
- Sponsor
- Ottawa Hospital Research Institute
Melanoma (Skin)
Cryotherapy With in Situ Immunotherapy in Melanoma Metastasis
Melanoma is the deadliest form of skin cancer and its incidence has doubled every 20 years in France, where this cancer is responsible of more than 1600 deaths each year.
- Trial name
- CRIRIN (NCT03949153)
- Testing
- Nivolumab 10 MG/ML Intravenous Solution [OPDIVO], Cryotherapy, Ipilimumab Injection
- Where
- France
- Volunteers
- 19 people
- Sponsor
- University Hospital, Strasbourg, France
Arthritis
Transarterial Embolization Versus Sham Procedure in Adults With Treatment-Resistant Inflammatory Arthritis of a Single Large Joint
The goal of this clinical trial is to learn whether transarterial embolization (TAE) can relieve pain and improve well-being in adults with inflammatory arthritis that remains active in only one large joint (wrist, elbow…
- Trial name
- ADVENTURE (NCT07873892)
- Testing
- Transarterial embolization with resorbable gelatin microspheres
- Volunteers
- 30 people
- Sponsor
- Istituto Ortopedico Rizzoli
Acute Cholecystitis
Randomized Trial of Percutaneous vs. Endoscopic Gallbladder Drainage
This is a randomized trial of patients with acute calculous cholecystitis who are never-surgery candidates. Patients will be randomized to one of two treatment groups, percutaneous cholecystostomy or endoscopic ultrasound-guided…
- Trial name
- PEG (NCT07696546)
- Testing
- Percutaneous cholecystostomy, EUS-guided gallbladder drainage
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Orlando Health, Inc.
Aneurysm, Arteriovenous Malformations
Patient Skin Dose in Interventional Radiology
Studies on radiation induced patients' skin lesions in interventional radiology highlighted the need for optimized and personalized patient dosimetry and adapted patient follow-up.
- Conditions
- Aneurysm, Arteriovenous Malformations, Coronary Occlusion, Lung Neoplasms
- Trial name
- DPPRI (NCT04246125)
- Testing
- Interventional radiology : skin dose measurements
- Where
- 5 sites in France
- Volunteers
- 87 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Anxiety, Paramedical Consultation
Pre-operative Interventional Paramedical Consultation: What About the Implantable Device?
The placement of implantable ports is carried out at CHUGA by several departments, including the Interventional Radiology Department.
- Trial name
- COPAIN (NCT07559981)
- Testing
- Paramedical consultation
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Grenoble
Skeletal Age Maturation
BASIC Study: Bone Age Study In Children
This study will see if the introduction of a hand outline on the Xray plate on which the child rests their hand will improve the quality of the Xray and reduce exposure to additional radiation by not having xrays repeated.
- Trial name
- BASIC (NCT04216914)
- Testing
- Hand outline
- Where
- United Kingdom
- Volunteers
- 56 people
- Sponsor
- Sheffield Children's NHS Foundation Trust
Image-Guided Biopsy - Carcinoma, Bronchogenic / Diagnosis- Outpatients
CT Scan Guide Percutaneous Biopsy of Lytic Bone Metastases of Lung Cancer : Contribution in Pathology Diagnosis and Molecular Biology
In case of primary lung cancer, bone metastases biopsy can be done in initial diagnosis or follow-up. Nevertheless, any study focus on rentability and biopsy complications of lytic bone lesion for the context of lung cancer.
- Trial name
- stasfa (NCT03386916)
- Testing
- CT scan guide percutaneous biopsy of lytic bone metastases of lung cancer
- Volunteers
- 80 people
- Sponsor
- University Hospital, Grenoble
Anesthesia, Sedation and Analgesia
Prospective IR-led Sedation Feasibility
This study wants to see if some interventional radiology (IR) procedures can be done without using general anesthesia. General anesthesia needs a lot of staff and equipment. It can also cause side effects.
- Conditions
- Anesthesia, Sedation and Analgesia, Interventional Radiology
- Trial name
- NCT07443254
- Testing
- ketamine, Fentanyl (IV), Midazolam
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- CAMC Health System
Hepatocellular Carcinoma
Synergistic Treatment for Hepatocellular Carcinoma (HCC) Using TACE With Antiangiogenesis
The purpose of this study is to investigate safety and potential therapeutic benefits for patients with hepatocellular carcinoma by transcatheter chemoembolization with the recombinant endostatin (commercially available in…
- Trial name
- TACE HCC (NCT00518557)
- Testing
- Transcatheter Arterial Chemoembolization
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Southeast University, China