Clinical trials: Radiotherapy; Image-Guided
Prostate Cancer, Image Guided Radiotherapy
PINPOINT Feasibility Study
This feasibility study is investigating the application of magnetic resonance imaging (MRI) and transperineal ultrasound (TPUS) to visualise potential sites of relapse and surrounding normal tissue in patient having…
- Trial name
- NCT05481372
- Testing
- Imaging
- Where
- United Kingdom
- Volunteers
- 14 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Prostate Cancer
Randomized Trial of Image -Guided Stereotactic Radiation Therapy (IG-SRT) in Prostate Cancer
Patients with low-risk or favorable intermediate-risk prostate cancer as defined by 1.2016 NCCN criteria will be eligible to participate on this study.
- Trial name
- NCT02911922
- Testing
- Endorectal Balloon, Rectal Spacer, Radiation therapy
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Weill Medical College of Cornell University
Lung Cancer (Non-Small Cell), Lung Metastases From Any Primary
Evaluation of Efficacy of Minimally Invasive Local Therapy for Lung Tumors and Its Impact on Breathing Function
This clinical study is evaluating different treatment options for patients with malignant lung tumors, including both primary lung cancer and tumors that have spread to the lungs from other parts of the body.
- Trial name
- NCT07272356
- Testing
- Surgery, Ablation, SBRT
- Where
- Lithuania
- Volunteers
- 68 people
- Sponsor
- Aurimas Macionis
Neoplasm Metastasis
Non-interventional Observational Study of Stereotactic Body Radiotherapy (SBRT) for Oligometastatic Cancer
The investigators recently published 2 phase II trials on the use of helical tomotherapy for oligometastatic colorectal cancer [1,2].
- Trial name
- NCT02228356
- Testing
- Stereotactic Body Radiation Therapy
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Universitair Ziekenhuis Brussel
Cervical Cancer
Hydrogel Spacer During Definitive Radiotherapy for Cervical Cancer
This prospective, single-center study will evaluate the feasibility, spatial stability, and dosimetric effects of an absorbable hydrogel spacer placed between the cervix/vagina and rectum before definitive radiotherapy for…
- Trial name
- Hydrogel-RT (NCT07904182)
- Testing
- Absorbable Hydrogel Spacer
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Breast Cancer
Pilot Study to Validate Metallic Markers for Image Guided Radiation Therapy for Breast Cancer Tx
The purpose of this study is to test metallic markers in the breast tissue after breast conserving surgery and to observe the metallic markers' stability in the breast for use as tumor bed markers and positioning devices for…
- Trial name
- NCT00802932
- Testing
- Non-contrast Computed Tomography (CT) Scans (Metallic Markers), Non-contrast CT Scans (Metallic Markers)
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Prostatic Adenocarcinoma
Dose Escalation Using Fiducial Markers in Image Guided Volumetric Modulated Arc Therapy to the Focal Lesion Micro Boost of Localized Prostate Cancer
Gold markers implanted in the prostate are used frequently for position verification of the prostate during external-beam radiotherapy.
- Trial name
- NCT03384199
- Testing
- Dose escalation to prostate focal lesion
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Kasr El Aini Hospital
Head and Neck Cancers, Breast Cancer
Feasibility Study of CBCT for IGRT in Cancer Patients
Cone beam computed tomography (CBCT) is an imaging technology that is incorporated into many modern radiation therapy systems. The quality of conventional CBCT is good enough to align patients for their daily radiation therapy…
- Conditions
- Head and Neck Cancers, Breast Cancer, Thoracic Cancers, Liver Cancer
- Trial name
- NCT06681233
- Testing
- Comparison of HyperSight CBCT imaging to conventional CBCT imaging.
- Where
- 4 sites in United States
- Volunteers
- 50 people
- Sponsor
- Varian, a Siemens Healthineers Company
Lumbar Disc Disease, Surgical Procedure, Unspecified
Evaluation of the Contribution of Intraoperative Scans Coupled With the Navigation for the Precision of the Positioning of the Pedicle Screws During a Lumbar Spine Surgery: a Prospective Randomised Study
Investigators team propose to evaluate the impact of the use of intraoperative scanning coupled with Stryker navigation, compared to the conventional fluoroscopy technique, on the accuracy of pedicle screws, in instrumented…
- Trial name
- SCANRACH (NCT04134975)
- Testing
- Spine surgery
- Where
- France
- Volunteers
- 126 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Head and Neck Cancer, Recurrence
BNCT and IG-IMRT for Recurrent Head and Neck Cancer
This is a boron neutron capture therapy (BNCT) combined with image-guided intensity modulation radiotherapy (IG-IMRT) for patients with previously irradiated and locally recurrent head and neck cancer.
- Trial name
- NCT02004795
- Testing
- BNCT + IG-IMRT
- Where
- Taiwan
- Volunteers
- 28 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Rectal Cancer
Cone Beam Computed Tomography (CT) (CBCT) With and Without a Customized Vacuum Immobilization Device (CVID)
This study is designed to investigate whether or not the use of a customized vacuum immobilization device (CVID) to immobilize rectal cancer patients undergoing preoperative pelvic radiation therapy improves the positional…
- Trial name
- NCT00937248
- Testing
- prone pillow and simple ankle fixation device, Customized Vacuum Immobilization Device (CVID)
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University Health Network, Toronto
Head and Neck Cancer, Oropharyngeal Cancer
A Pilot Trial of Image-Guided Adaptive Radiotherapy for Head and Neck Cancer
The goal of this clinical research study is to use computed tomography (CT) scans to measure and guide your radiation therapy. Researchers want to learn if the CT scans can be used to adapt radiation therapy to the changes in…
- Trial name
- NCT00490282
- Testing
- Intensity Modulated Radiation Therapy, Adaptive Radiotherapy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- M.D. Anderson Cancer Center
Radiotherapy, Radiotherapy, Image-Guided
Patient Position Monitoring System for Beam Gated Radiation Therapy of Malignancies of the Chest and Upper Abdomen
This study will evaluate the feasibility of using this novel patient position monitoring system for patients receiving radiation therapy to targets involving the chest or upper abdomen, as these are the most affected by…
- Trial name
- NCT07373496
- Testing
- Patient Position Monitoring System
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Washington University School of Medicine
Breast Cancer
Radiation Therapy Followed by Surgery in Treating Patients With Early-Stage Breast Cancer
RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Giving CT-guided accelerated radiation therapy before surgery may make the tumor smaller and reduce the amount of normal tissue that needs to be removed.
- Trial name
- PAPBI (NCT01024582)
- Testing
- biopsy, fine-needle aspiration, accelerated partial breast irradiation
- Where
- Netherlands
- Volunteers
- 139 people
- Sponsor
- The Netherlands Cancer Institute
Lung Neoplasm, Pelvic Neoplasm
Personalized Estimation of Doses Delivered During Image Guided Radiation Therapy Tests
In image-guided radiotherapy (IGRT), the repeated and increasingly intensive use of on-board positioning imaging, using 2D or 3D Mega-Volt (MV) or kilo-Volt (kV) imaging devices (cone-beam or CBCT scanners), is leading the…
- Conditions
- Lung Neoplasm, Pelvic Neoplasm, Breast Cancer, Cancer, Otorhinolaryngeal
- Trial name
- ELISA (NCT05258383)
- Testing
- 3D maps of physical doses
- Where
- 9 sites in France
- Volunteers
- 320 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cancer of the Prostate
Prostate-Rectal Separation With PEG Hydrogel and Its Effect on Decreasing Rectal Dose
This is a Phase I prospective study of 30 patients to determine whether PEG hydrogel (SpaceOAR) reduces the dose of radiation delivered to the rectum during Image Guided Intensity Modulated Radiotherapy (IG-IMRT) for prostate…
- Trial name
- NCT02212548
- Testing
- PEG Hydrogel (SpaceOAR)
- Where
- Australia
- Volunteers
- 30 people
- Sponsor
- Royal North Shore Hospital
Prostate Cancer
Tumor-directed Radiation Therapy for Patients With the Highest Risk Category of Localized Prostate Cancer
HYPO-RT-PC boost is is an open-label, multicentre, phase II trial evaluating safety and efficacy of real-time image-guided tumor-directed ultra-hypofractionated radiation boost and lymph node irradiation for patients with…
- Trial name
- NCT06220435
- Testing
- Ultra-hypofractionated radiotherapy regimen.
- Where
- 2 sites in Sweden
- Volunteers
- 76 people
- Sponsor
- Region Skane
Prostate Cancer
Hypo-fractionated Radiation Therapy With or Without Androgen Suppression for Intermediate Risk Prostate Cancer
The purpose of this study is to compare the effects, good and/or bad of two treatment methods on subjects and their cancer. Proton beam radiation therapy is one of the treatments for men with prostate cancer who have localized…
- Trial name
- NCT01492972
- Testing
- Radiation, Androgen Suppression Therapy
- Where
- 4 sites in United States
- Volunteers
- 192 people
- Sponsor
- Proton Collaborative Group
Head and Neck Cancer
Image-Guided Adaptive Radiotherapy for in Detecting Tumors During Treatment in Patients With Head and Neck Cancer
This clinical trial studies image-guided adaptive radiotherapy in detecting tumors during treatment in patients with head and neck cancer.
- Trial name
- NCT01843673
- Testing
- computed tomography, cone-beam computed tomography, radiography
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Virginia Commonwealth University
Breast Cancer
Partial Breast Irradiation in a Low-risk Population Screened With MRI
This is a pilot study to determine if partial breast irradiation (PBI) limited to the region of the tumor bed following lumpectomy in patients screened with MRI provides historically similar rates of local failure, limited acute…
- Trial name
- NCT01255553
- Testing
- Partial Breast Irradiation
- Where
- United States
- Sponsor
- University of Chicago