Clinical trials: Randomized, open to volunteers
ICU Delirium
Modified Hospital Elder Life Program at Intensive Care Unit
Delirium, a form of acute brain dysfunction, occurs in up to 81% of patients receiving mechanical ventilation in the intensive care unit (ICU).
- Trial name
- mHelp@ICU (NCT06054828)
- Testing
- mHELP@ICU
- Where
- Taiwan
- Volunteers
- 266 people
- Sponsor
- National Taiwan University Hospital
Hepatocellular Carcinoma
DEB-TACE With Visualable Microspheres Versus PVA Microspheres for HCC
This study will evaluate the safety and efficacy of DEB-TACE with visualable embolization microspheres versus PVA microspheres for hepatocellular carcinoma.
- Trial name
- NCT06190665
- Testing
- DEB-TACE with visualable microspheres, DEB-TACE with PVA microspheres
- Where
- 2 sites in China
- Volunteers
- 188 people
- Sponsor
- Zhongda Hospital
Gastritis, Acute Gastritis
Phase 4 Study of Sto M Tab. in Acute or Chronic Gastritis
This Phase 4, multicenter, randomized, double-blind, active-controlled, non-inferiority study aims to evaluate the non-inferiority of Stoem Tab. compared to Stillen Tab.
- Conditions
- Gastritis, Acute Gastritis, Chronic Gastritis
- Trial name
- NCT07631065
- Testing
- Stillen Tab., Sto M Tab.
- Volunteers
- 470 people
- Sponsor
- Mather's Pharm. Co., Ltd.
Behavioral Health
Behavioral Health Initial Intake Outreach
The goal of this study is to help patients get seen sooner for behavioral health appointments by informing them about group therapy options, which allow more patients to be seen at once, often more quickly than 1:1 therapy.
- Trial name
- NCT07790107
- Testing
- Pre-intake appointment informational messages
- Where
- United States
- Volunteers
- 6,200 people
- Sponsor
- Geisinger Clinic
Cervical Cancer Metastatic, Cervical Cancer Recurrent
A Prospective, Randomized, Parallel Trial of Famitinib Malate at Different Doses Combined With Camrelizumab for the Treatment of Recurrent and Metastatic Cervical Cancer
This study is a prospective, randomized, parallel investigation aimed at evaluating different doses of famitinib malate (20mg, 15mg, or 10mg, once daily, respectively) by analyzing the pharmacokinetics, efficacy, safety, and…
- Trial name
- NCT07143292
- Testing
- Famitinib + Camrelizumab
- Volunteers
- 120 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Acute Ischemic Stroke
Cerebrolysin After Reperfusion in Extended-window EndoVascular Thrombectomy
Acute ischemic stroke caused by blockage of a large brain artery can lead to severe disability. Endovascular thrombectomy is a catheter-based procedure used to remove the blood clot and restore blood flow.
- Trial name
- CARE-EVT (NCT06339411)
- Testing
- Cerebrolysin
- Volunteers
- 100 people
- Sponsor
- Chang Gung Memorial Hospital
Postoperative Urinary Retention (POUR)
Electroacupuncture on Postoperative Urinary Retention After Radical Surgery for Cervical Cancer
This is a prospective, blinded, single-center, randomized controlled trial. Investigators will include 208 patients with postoperative urinary retention (POUR) after radical hysterectomy for cervical cancer who have a clear…
- Trial name
- NCT07253194
- Testing
- EA intervention
- Where
- China
- Volunteers
- 208 people
- Sponsor
- Lu Chao
Insomia Disorder
A Trial to See if Daridorexant Can Help Adults and Elderly People With Insomnia Sleep Better During the Night and Function Better During the Day
The purpose of this clinical trial is to collect more data about the effect of daridorexant in adults and elderly people with insomnia disorder.
- Trial name
- DARI-DREAM (NCT07843329)
- Testing
- Daridorexant
- Volunteers
- 344 people
- Sponsor
- Idorsia Pharmaceuticals Ltd.
IgA Nephropathy (IgAN)
The Randomized Controlled Study of Shenqi Yishen Granules in the Treatment of IgA Nephropathy
The goal of this clinical trial is to learn if Shenqi Yishen Granules works to treat IgA Nephropathy in adults. It will also learn about the safety of Shenqi Yishen Granules.
- Trial name
- NCT07360002
- Testing
- Shenqi Yishen Granules
- Volunteers
- 102 people
- Sponsor
- Keda Lu
Mouthwash, Chlorhexidine
Evaluation of the Anti-Plaque Effect of a Resveratrol-Based Mouthwash Using a 24-Hour Plaque Re-Growth
Dental plaque is a biofilm that accumulates on tooth surfaces and is a primary factor in the development of gingival inflammation.
- Conditions
- Mouthwash, Chlorhexidine, Biofilm Formation, Periodontal Health
- Trial name
- NCT07393802
- Testing
- Resveratrol-Based Mouthwash, Chlorhexidine Gluconate 0.12 % Mouthwash
- Where
- Iraq
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Muscle-invasive Bladder Cancer
Tetra-modality Bladder Preservation Strategies in Muscle-invasive Bladder Cancer: TURBT+ Chemo/Immunotherapy+ Radiation Therapy+ Maintenance Immunotherapy vs. W&W
The purpose of this study is to assess the efficacy and safety of adding the immunotherapy Avelumab as a fourth component, alongside tumor removal, chemotherapy, and radiation, to increase the chance of preserving the bladder in…
- Trial name
- NCT06686381
- Testing
- Maximum TURBT, Chemotherapy + Immunotherapy Induction, Radiotherapy
- Where
- Lebanon
- Volunteers
- 80 people
- Sponsor
- American University of Beirut Medical Center
Acute Pancreatitis (AP)
A Trial of the Arctx Cool Catheter in Acute Pancreatitis
Researchers will compare people who get the ACC Set plus standard of care to people who get standard of care alone. This will show whether adding the ACC Set helps.
- Trial name
- CHILL-AP (NCT07698119)
- Testing
- Treatment, Control
- Volunteers
- 200 people
- Sponsor
- Arctx Medical, Inc.
Crowding of Anterior Mandibular Teeth
Evaluating the Efficacy of Micro-Osteoperforations Technique on the Orthodontic Tooth Movement Acceleration in Moderate Mandibular Anterior Crowding Cases Treated With Clear Aligners
Patients with moderate mandibular anterior crowding will be treated in this study. The efficacy of micro-osteoperforations technique by special drill in accelerating orthodontic tooth movement during clear aligners therapy will…
- Trial name
- NCT05492773
- Testing
- Micro-osteoperforations Technique, Active comparater
- Where
- Syria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hama University
Atrial Fibrillation, Obesity and Obesity-related Medical Conditions
Metabolic Surgery for Atrial Fibrillation Elimination
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia. It is estimated that between 3 and 6 million Americans are currently living with AF, while 12 million people in the United States will have AF in 2030.
- Trial name
- METSAFE (NCT07027969)
- Testing
- Roux-en-Y Gastric Bypass or Sleeve Gastrectomy, Anti-Obesity Medication (AOM) treatment
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ali Aminian
Breast Cancer
Artificial Intelligence (AI)-Based Personalized Exercise Coaching for Patients With Breast Cancer
This prospective, single-center, randomized controlled trial aims to evaluate the effectiveness and safety of an artificial intelligence (AI)-based personalized exercise coaching system in female breast cancer survivors who have…
- Trial name
- NCT07844941
- Testing
- AI-Based Personalized Exercise Coaching, Conventional Exercise Guidance
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Chronic Migraine
Laser Acupuncture for Chronic Migraine
A single-blind randomized controlled trial was conducted from October 2024 to May 2025. Chronic migraine patients were randomly assigned in a 1:1 ratio to receive either Laser acupuncture or sham treatment.
- Trial name
- LAFCM (NCT06219694)
- Testing
- Laser Acupuncture
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Taichung Veterans General Hospital
Hepatitis B
Comparison of TAF and TDF in Preventing Mother-to-Child Transmission of HBV in Pregnancies With High Viral Loads
The main objective of this study is to compare the mother-to-infant transmission rates of hepatitis B between pregnant women receiving treatment with tenofovir alafenamide and those receiving treatment with tenofovir disoproxil…
- Trial name
- NCT06947356
- Testing
- TAF group, TDF group
- Where
- 10 sites in China
- Volunteers
- 210 people
- Sponsor
- Guangzhou 8th People's Hospital
Suicidal Ideation and Behavior, Suicide
RomSi: Mobile Health Intervention to Enhance Suicide Prevention by Reducing Stigma and Increasing Literacy
Suicide is one of the leading causes of death in Spain, representing a public health crisis that requires urgent and effective solutions.
- Trial name
- NCT06759129
- Testing
- Immediate-use of a mobile health application until completion, Delayed use of a mobile health application until completion
- Where
- Spain
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Difficult Mechanical Ventilation Weaning, Spontaneous Breathing Trial
Non-medicinal Technique and Dyspnea in Weaning Patients
This is a randomized, controlled, multicenter, open-label, category 2, parallel-arm study of efficacy and superiority. The target population are patients hospitalized in the intensive care unit (ICU), ventilated with invasive…
- Conditions
- Difficult Mechanical Ventilation Weaning, Spontaneous Breathing Trial, Dyspnea
- Trial name
- Easy Wean (NCT06926231)
- Testing
- Protocolized medical hypnosis, Protocolized standard of care
- Where
- 5 sites in France
- Volunteers
- 82 people
- Sponsor
- Hospices Civils de Lyon
Postoperative Wound Care After TKA
Evaluation of Ioband Coverage Waterproof Dressing Versus Isolated Waterproof Dressing After Primary Total Knee Arthroplasty
Title: Evaluation of Ioband® Coverage Waterproof Dressing in Post-Operative Total Knee Arthroplasty (TKA) Goal: To evaluate the effectiveness of Ioband® coverage waterproof dressing compared to standard waterproof dressing in…
- Trial name
- Wound coverage (NCT06943053)
- Testing
- Isolate waterproof dressing (Opsite), Ioban coverage group
- Where
- 2 sites in Thailand
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Thammasat University Hospital
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