Clinical trials: Randomized-controlled Trial
Stroke
F@ce 2.0 a Mobile Phone-supported and Family-centred Rehabilitation Intervention After Stroke in Uganda
The purpose of the present proposal is to implement and evaluate a new model for mobile phone supported and family-centred rehabilitation intervention (F@ce 2.0) with regard to functioning in activities in daily living and…
- Trial name
- NCT04337034
- Testing
- Mobile phone supported and family-centred rehabilitation, Information and blood pressure measurement
- Where
- 3 sites in Uganda
- Volunteers
- 98 people
- Sponsor
- Karolinska Institutet
Abdominal Cancer, Thoracic Cancer
Validate the Safety and Feasibility of the CT-guided Interventional Robot in Percutaneous Biopsy Procedure.
This multicenter, randomized controlled trial aims to investigate whether the interventional robot can be well and safely used for percutaneous needle biopsy compared with the freehand needle biopsy method under CT guidance in…
- Trial name
- NCT06484764
- Testing
- CT-fluoroscopy guided robot-assisted biopsy of thoracic and abdominal lesions, Freehand CT-guided percutaneous needle biopsy of thoracic and abdominal lesions
- Where
- 3 sites in China
- Volunteers
- 166 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Hypertension
STITCH (Simplified Therapeutic Intervention To Control Hypertension)
The objective of this study is to assess whether the implementation of a primary treatment algorithm using a fixed dose combination therapy will improve the management of hypertension when compared to usual management.
- Trial name
- NCT00129909
- Testing
- fixed dose combination therapy
- Where
- Canada
- Volunteers
- 2,081 people
- Sponsor
- University of Western Ontario, Canada
Respiratory Failure
CTSI-iPad for Vented Patient Communication
This study will enroll 75 mechanically vented adults in the ICU to compare self-reported ease of communication, patient satisfaction, and patient anxiety and frustration levels between a group using a communication application on…
- Trial name
- iPad (NCT03163823)
- Testing
- Proloquo2Go, Standard of Care
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Medical College of Wisconsin
Airway Management
Apneic Intubation Critically Ill Children
This study compares the actual standard of care of intubation in Swiss pediatric intensive care units vs the use of apneic oxygenation using either high flow or low flow oxygen to prevent hypoxemia and to prolong apnea time…
- Trial name
- Penguin (NCT04890288)
- Testing
- Interventional randomized controled trial (RCT) comparing two oxygenation methods to reduce desaturation during intubation vs standard of care.
- Where
- 7 sites in Switzerland
- Volunteers
- 210 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Transcranial Magnetic Stimulation, Behavioral and Psychological Symptoms in Alzheimer's Disease
Network-Guided Individualized TMS for BPSD in Alzheimer's Disease: A Double-blind Randomized Controlled Trial
Evaluate the safety and efficacy of personalized network-guided transcranial magnetic stimulation for treating behavioral and psychological symptoms in patients with Alzheimer's disease.
- Conditions
- Transcranial Magnetic Stimulation, Behavioral and Psychological Symptoms in Alzheimer's Disease, Individualized Navigation
- Trial name
- NET-BPSD (NCT07692542)
- Testing
- transcranial magnetic stimulation
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Anhui Medical University
Pregnancy
The Effect of Ultrasound Visual Feedback on Birth Outcomes in Nulliparous Women With Levator Ani Muscle Co-activation at Term Pregnancy
The study aims to evaluate the effect of ultrasound-based visual feedback training of the pelvic floor muscles in nulliparous women at term pregnancy who present co-activation of the levator ani muscle, on the duration of the…
- Trial name
- CoA_2025 (NCT07675642)
- Testing
- Ultrasound Visual Feedback Training
- Where
- Italy
- Volunteers
- 204 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Awake, Thoracic Epidural Anesthesia
Awake Thoracic Epidural Anesthesia Versus General Anesthesia in Thoracotomy
This study aims to compare awake thoracic epidural anesthesia and general anesthesia in thoracotomy.
- Conditions
- Awake, Thoracic Epidural Anesthesia, General Anesthesia, Thoracotomy
- Trial name
- NCT06930183
- Testing
- Awake thoracic epidural anesthesia, General anesthesia
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Polycystic Ovarian Syndrome (PCOS), Infertility
Theta Healing-Based Intervention in Women With Polycystic Ovary Syndrome
This randomized controlled study aims to evaluate the effect of a Theta Healing-based intervention on fertility concerns, self-compassion, and body image in women diagnosed with Polycystic Ovary Syndrome (PCOS).
- Conditions
- Polycystic Ovarian Syndrome (PCOS), Infertility, Psychological Stress
- Trial name
- NCT07630441
- Testing
- Theta Healing-Based Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 142 people
- Sponsor
- Ankara Medipol University
Malocclusion of Anterior Teeth
Evaluation of Self-ligating Brackets Plus Minor Surgery in Treating Crowded Cases of Malocclusion
Patients at the Orthodontic Department of University of Damascus Dental School will be examined and subjects who meet the inclusion criteria will be admitted then the initial diagnostic records (diagnostic gypsum samples …
- Trial name
- NCT03647241
- Testing
- Self-Ligating Brackets, Traditionally-Ligated Brackets, Corticotomy
- Where
- Syria
- Volunteers
- 60 people
- Sponsor
- Damascus University
CDKL5 Deficiency Disorder
Efficacy and Safety of Daily Home-based Hyperthermic Baths for Reducing Epileptic Seizures in CDKL5 Deficiency Disorder: A PROBE Clinical Trial
The primary objective of this research is to study the efficacy and safety of daily, home-based hyperthermic baths for reducing epileptic seizures in CDKL5 Deficiency Disorder.
- Trial name
- NCT07602205
- Testing
- Home-based hyperthermic Baths
- Volunteers
- 34 people
- Sponsor
- Xuanwu Hospital, Beijing
Immediate Dental Implants Connective Tissue Graft Esthetic Zone
Facial Gingival Level Evaluation Following Soft Tissue Augmentation Using CTG Around Immediate Dental Implants vs Immediate Dental Implants Alone in the Esthetic Zone.
Aim of current study to evaluate connective tissue graft combined with immediate implant placement as an innovative option for less facial gingival tissue recession, less pocket depth and less clinical attachment loss versus…
- Trial name
- NCT03334994
- Testing
- Intervention group:(Group B) connective tissue graft combined with immediate implant.
- Where
- Egypt
- Volunteers
- 18 people
- Sponsor
- Cairo University
Dialysis, Chronic Kidney Disease
Next Generation Advanced Insulin Delivery System in Adults With Diabetes and Advanced Renal Disease
The goal of this this randomized, clinical trial is to test an automated insulin delivery system (AID) in people with type 1 or type 2 diabetes who are on hemodialysis, peritoneal dialysis, or have advanced chronic kidney disease…
- Conditions
- Dialysis, Chronic Kidney Disease, Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1
- Trial name
- NCT06330194
- Testing
- 2nd Generation Automated Insulin Delivery (AID) system
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- Steno Diabetes Center Copenhagen
Myocardial Injury After Noncardiac Surgery (MINS), Myocardial Ischemia
Ivabradine for Prevention of Myocardial Injury After Noncardiac Surgery Trial (PREVENT-MINS)
This study is a multicentre, randomized controlled trial of ivabradine versus placebo.
- Trial name
- PREVENT-MINS (NCT05279651)
- Testing
- Ivabradine
- Where
- 26 sites in Poland
- Volunteers
- 2,146 people
- Sponsor
- Jagiellonian University
Attention Deficit Disorder With Hyperactivity
The Effects of a Peer Co-led Educational Programme for Parents of Children With ADHD
ADHD is associated with a substantial burden on families, and systems pertaining to health, social care, and criminal justice, and there is a need for more knowledge of the effects of non-pharmacological interventions.
- Trial name
- ADHD (NCT04010851)
- Testing
- Peer co-led educational group, Comparator treatment as usual
- Sponsor
- Norwegian University of Science and Technology
Chronic Insomnia Disorder
Online Tai Chi Versus Digital CBT-I for Chronic Insomnia
This multicenter randomized controlled trial will compare online Tai Chi (OTC) with digital cognitive behavioral therapy for insomnia (dCBT-I) in adults with chronic insomnia disorder.
- Trial name
- NCT07853651
- Testing
- Online Tai Chi, Digital Cognitive Behavioral Therapy for Insomnia
- Where
- China
- Volunteers
- 172 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Procedural Sedation
Dexmedetomidine Versus Chloral Hydrate for Pediatric Sedation During EEG
The purpose of the study is: 1. To compare the efficacy of dexmedetomidine versus chloral hydrate as pediatric sedation agents for EEG studies.
- Trial name
- NCT00464451
- Testing
- Dexmedetomidine, Chloral hydrate
- Where
- United States
- Sponsor
- Wesley Medical Center
Immunity
Efficacy and Safety of Nokyong Mixture Extract(CME-PI) on Promotion of Immunity
This study was conducted to investigate the efficacy and Safety of Nokyong Mixture Extract(CME-PI) on Promotion of Immunity
- Trial name
- NCT04010331
- Testing
- Nokyong Mixture Extract(CME-PI)
- Where
- South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Chonbuk National University Hospital
Nutrition, Healthy, Weight Loss
Effect of a Postbiotic Supplementation in Overweight and Obese Subjects: A Randomized Controlled Trial (PARABIOTICS-2).
The principal objective of this project is to evaluate the effect of a postbiotic supplement (inactivated microorganism) on body composition and other physiological and metabolic parameters related to excess body weight in…
- Conditions
- Nutrition, Healthy, Weight Loss, Overweight and Obesity
- Trial name
- PARABIOTICS-2 (NCT07165431)
- Testing
- Postbiotic + nutritional recommendations
- Where
- Spain
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Postpartum Urinary Incontinence, Postpartum Depression (PPD)
Prenatal Exercise Including Perineal Massage and Maternal-Neonatal Outcomes
The study is divided into three phases: Phase 1: Baseline survey to obtain an overall understanding of the current situation of voluntary participation in prenatal perineal massage.
- Conditions
- Postpartum Urinary Incontinence, Postpartum Depression (PPD), Neonatal Complications, Gestational Diabetes
- Trial name
- PEPM-RCT (NCT07314502)
- Testing
- Supervised prenatal exercise including antenatal perineal massage
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- South China Normal University
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