Clinical trials: Randomized-controlled Trial
Depression
Step Away From Depression - Evaluation of a Pedometer Intervention With Inpatients With Major Depression
The purpose of this study is to determine if the use of pedometers can help depressive inpatients in psychiatric clinics to increase their level of physical activity.
- Trial name
- SAD (NCT02850341)
- Testing
- Pedometer
- Where
- 9 sites in Austria, Germany
- Volunteers
- 292 people
- Sponsor
- Charite University, Berlin, Germany
Type 2 Diabetes
Type 2 Continuous Glucose Monitoring Academy
The goal of this clinical trial is to evaluate the Impact of Continuous Glucose Monitoring Academy Education Curriculum Versus Standard Care on Glycemic Outcomes for Youth With Type 2 Diabetes (T2D): The first aim is to determine…
- Trial name
- NCT06516640
- Testing
- Continuous Glucose Monitoring Academy, Standard Education
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Children's Hospital Los Angeles
Voice Alteration
Effects of Finger Kazoo Exercise With and Without Oropharyngeal Enlargement in the Operatic Singing Voice
This clinical trial aimed to evaluate the effects of the semi-occluded vocal tract exercise Finger Kazoo (FK), with and without oropharyngeal expansion, on the singing voice.
- Trial name
- FIKVOX (NCT07129668)
- Testing
- Condition A, Condition B
- Where
- Portugal
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Aveiro University
Anti-CCP Positive Early Rheumatoid Arthritis
Effect Assessment of Periodontal Prophylaxis on Rheumatoid Arthritis Activity.
The purpose of this study is to assess the impact of an intervention (scaled every 06 months associated with the use of mouthwash with essential oils (toothpaste and Listerine® 2 times / day containing polymer Triclosan (Colgate…
- Trial name
- BHYRRA (NCT01706874)
- Testing
- Periodontal prophylaxis
- Where
- France
- Volunteers
- 92 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Influenza and Acute Respiratory Viral Infections
Efficacy of Anaferon for Children in the Treatment of Influenza and Acute Respiratory Viral Infections in Children
The purpose of this study is: To obtain additional data on therapeutic efficacy of Anaferon for children in the treatment of influenza and acute respiratory viral infections in children
- Trial name
- NCT02072174
- Testing
- Anaferon for Children
- Where
- 27 sites in Belarus, Russia and 1 more
- Volunteers
- 569 people
- Sponsor
- Materia Medica Holding
Periodontitis
Injectable Platelet Rich Fibrin in Periodontal Treatment
The aim of this randomized controlled parallel clinical trial is to investigate the efficacy of injectable Platelet Rich Fibrin (iPRF) as an adjunctive to non-surgical periodontal therapy (STEP 1 \& 2 of periodontal treatment).
- Trial name
- I-PRF (NCT06814418)
- Testing
- Non-surgical periodontal treatment, Injectable Platelet Rich Fibrin (I-PRF)
- Where
- Greece
- Volunteers
- 32 people
- Sponsor
- Aristotle University Of Thessaloniki
High Tone Pelvic Floor Dysfunction
Comparing Adjuvant Treatments for High Tone Pelvic Floor Dysfunction
The researchers are comparing two treatments for high tone pelvic floor dysfunction (HTPFD) in conjunction with pelvic floor physical therapy (PFPT).
- Trial name
- NCT07404397
- Testing
- Cyclobenzaprine, Pelvic floor massage wand, Pelvic floor physical therapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Michigan
Depression, Anxiety
Feasibility and Acceptability of W-GenZD vs CBT-light Teletherapy for Adolescents Seeking Mental Health Services
The primary aim of this study is to determine the feasibility and acceptability of the W-GenZD mobile application among a group of adolescents and who have screened and triaged into low-intensity treatment within the Children's…
- Trial name
- NCT05372913
- Testing
- Woebot for Adolescents (W-GenZD) Mobile Application, CBT-Lite Teletherapy Group
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- Woebot Health
Carcinoma, Gastrointestinal Diseases
XELOX Combined With Anlotinib and Penpulimab vs XELOX as Adjuvant Therapy in ctDNA Positive Gastric and Esophagogastric Junction Adenocarcinoma
This is an open label, randomized, phase Ⅱ, multi-cohort study to treat subjects with ctDNA Positive Gastric and Esophagogastric Junction Adenocarcinoma.
- Conditions
- Carcinoma, Gastrointestinal Diseases, Stomach Cancer, Gastroesophageal-junction Cancer
- Trial name
- EXPLORING (NCT05494060)
- Testing
- Anlotinib hydrochloride capsule, Penpulimab Injection, XELOX
- Where
- China
- Volunteers
- 80 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
MDD
Effect of Magnesium Supplementation in Selective Serotonin Reuptake Inhibitors Treated Major Depressive Disorder Patients
A randomized, double-blind, placebo-controlled trial was conducted to assess the effect of magnesium glycinate on symptoms of moderate to severe depression in 90 patients.
- Trial name
- NCT04880460
- Testing
- Magnesium Glycinate tablet 200mg
- Where
- Bangladesh
- Volunteers
- 90 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Esophageal Cancer, Surgery--Complications
Preemptive Endoluminal Negative Pressure in Minimally Invasive Transthoracic Esophagectomy
The primary objective of the preSponge randomized controlled trial (RCT) will be to assess the potential protective effects of preemptive endoscopic negative pressure therapy (ENP) on postoperative morbidity in high-risk patients…
- Conditions
- Esophageal Cancer, Surgery--Complications, Leak, Anastomotic
- Trial name
- NCT04162860
- Testing
- Eso-SPONGE® device
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University of Zurich
Pre-frail Elderly
The Effect of SOD Enzyme on Frailty and HRQOL Among Indonesian Pre-frail Elderly: A Double Blind Randomized Controlled Trial
The primary objective is to determine the effect of SOD enzyme on frailty and health related quality of life among Indonesian pre-frail elderly.
- Trial name
- NCT02753582
- Testing
- SOD+Gliadin Capsule
- Where
- Indonesia
- Volunteers
- 150 people
- Sponsor
- Universitas Indonesia
Covid19
RCT,Double Blind, Placebo to Evaluate the Effect of Zinc and Ascorbic Acid Supplementation in COVID-19 Positive Hospitalized Patients in BSMMU
The first COVID-19 case was identified on March 7, 2020. Since then, 4127 deaths of the total 3,40583 confirmed cases are reported in Bangladesh of August 26, 2020.
- Trial name
- NCT04558424
- Testing
- zinc gluconate and ascorbic acid
- Where
- Bangladesh
- Volunteers
- 50 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Trigeminal Neuralgia, Pain
Clinical Trial of Hyperbaric Oxygen Treatment in Trigeminal Neuralgia Patients
The purpose of this study is to determine whether the hyperbaric oxygen treatment reduces pain and improve the life quality in trigeminal neuralgia patients.
- Trial name
- NCT00866424
- Testing
- Hyperbaric oxygen, Mock hyperbaric chamber
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Xijing Hospital
Posterior Root Tear of the Medial Meniscus, Arthroscopic Transtibial Pullout Suture Repair
Arthroscopic Transtibial Pullout Suture Repair Versus Suture Anchor Repair in Posterior Root Tear of the Medial Meniscus
The menisci play a fundamental role in maintaining normal knee biomechanics by distributing load, absorbing shock, providing stability, and facilitating joint lubrication.
- Conditions
- Posterior Root Tear of the Medial Meniscus, Arthroscopic Transtibial Pullout Suture Repair, Suture Anchor Repair
- Trial name
- NCT07408323
- Testing
- Arthroscopic Transtibial Pullout Suture Repair, Suture Anchor Repair
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Al-Azhar University
Calcific Tendinitis of Shoulder
Ultrasound-Guided Extracorporeal Shock Wave Therapy for Calcific Tendinitis
Calcific tendinitis of the shoulder is a debilitating musculoskeletal condition that significantly impacts the working-age population, typically those between 30 and 60 years of age.
- Trial name
- ESWT (NCT07756307)
- Testing
- Ultrasound guide localization, Palpation localization
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Taipei Medical University WanFang Hospital
Mitral Valve Repair Surgery
Safety and Effectiveness of Early Aspirin Administration After Mitral Valve Repair
This study compares the efficacy and safety of two different antithrombotic drugs, warfarin and aspirin, in early application after mitral valve repair (MVRep).
- Trial name
- NCT06738992
- Testing
- Aspirin, Warfarin
- Where
- China
- Volunteers
- 384 people
- Sponsor
- Guangdong Provincial People's Hospital
HIV (Human Immunodeficiency Virus), Pain
Auricular Point Acupressure for Pain
The goal of this pilot clinical trial is to learn whether auricular point acupressure (APA) can help reduce chronic musculoskeletal pain in adults age 50 and older who are living with HIV.
- Trial name
- NCT07852611
- Testing
- Auricular Point Acupressure
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Dan Song
Chronic Pruritus
Treatment of Chronic Itch in Patients Under Arsenic Exposure With Naloxone
The purpose of this study is to assess the efficacy and safety of sublingual naloxone in the treatment of chronic itch in patients under arsenic exposure.
- Trial name
- NCT03751111
- Testing
- Naloxone
- Where
- China
- Volunteers
- 126 people
- Sponsor
- Xiangya Hospital of Central South University
Rectal Cancer
Neoadjuvant Fruquintinib Plus Tislelizumab Combined With mCapeOX Versus CapeOX for Mid-high pMMR/MSS Locally Advanced Rectal Cancer
The goal of this clinical trial is to learn if neoadjuvant Fruquintinib and Tislelizumab combined with mCapeOX works to treat mid-high pMMR/MSS locally advanced rectal cancer patients compared with CapeOX.
- Trial name
- PKUCH-R09 (NCT06443671)
- Testing
- CapeOX, Fruquintinib and Tislelizumab combined with mCapeOX
- Where
- China
- Volunteers
- 132 people
- Sponsor
- Peking University Cancer Hospital & Institute
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