Clinical trials: Rapid Diagnosis
Critical Illness, Fasting State
Ketosis, Immune Function and Metabolic Adaptation in Response to Short-term Fasting in Critical Illness
KETO-FAST is a pre-planned translational substudy of the FAST-ICU cluster-randomized cross-over trial. The substudy will characterize ketone body production and associated metabolic, autophagy-related, and immune cellular…
- Conditions
- Critical Illness, Fasting State, Ketosis, Nutrition
- Trial name
- KETO-FAST (NCT07738536)
- Testing
- Delayed nutrition, Standard nutrition, Fasting
- Where
- Sweden
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Karolinska University Hospital
Breast Cancer
Application of Rapid On-site Evaluation in Lymph Node Biopsy of Breast Cancer
The goal of this clinical trial is to evaluate the value of rapid on-site evaluation（ROSE） in lymph node biopsy of breast cancer.
- Trial name
- NCT06495736
- Testing
- Experimental: ROSE technique stain
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Yunnan Cancer Hospital
Preeclampsia
CercaTest™ Red Urine Test for Predicting Preeclampsia
The goal of this observational study is to predict preeclampsia in pregnant women aged 18 years or older with a singleton pregnancy at 20 or more weeks of gestation who present with suspected signs or symptoms of preeclampsia.
- Trial name
- PRE-CERCA (NCT07625501)
- Where
- Hong Kong
- Volunteers
- 1,000 people
- Sponsor
- Chinese University of Hong Kong
Depression
Evaluation of the Initial Prescription of Ketamine and Milnacipran in Depression in Patients With a Progressive Disease
KetaPal is a placebo-controlled randomized trial designed to demonstrate the antidepressant action of ketamine in palliative care situations.
- Trial name
- KETAPAL (NCT02783430)
- Testing
- Ketamine, Milnacipran
- Where
- 9 sites in France
- Volunteers
- 42 people
- Sponsor
- University Hospital, Lille
Acute Myeloid Leukemia, Adult
Individualized Induction Therapy for Non-elderly Acute Myeloid Leukemia Patients With Adverse Risk Features
Individualized induction therapy will be applied to the non-elderly acute myeloid leukemia (AML) patients with adverse genetic risk features guided by rapid screening with fluorescence in situ hybridization (FISH) and…
- Trial name
- NCT04752527
- Testing
- venetoclax combined with decitabine
- Where
- China
- Volunteers
- 42 people
- Sponsor
- The First Affiliated Hospital of Soochow University
Partially Edentulous Patients
Manually Versus Digitally Fabricated Removable Partial Dentures
In the clinical trial, the Computer Aided Design/Computer Aided Manufacturing (CAD/CAM) fabricated removable partial dentures (RPD's) are evaluated on casts and clinically compared with a traditional fabricated RPD for 50…
- Trial name
- NCT01191073
- Testing
- CAD/CAM fabricated RPD's, traditional fabricated RPD's
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- University Ghent
Covid19
Evaluation of the INDICAID™ COVID-19 Rapid Antigen Test
The INDICAID™ Rapid Antigen Test was used in real-world outbreak testing. The antigen test was used together with PCR testing. This study was designed to evaluate whether the addition of a rapid antigen test decreased time to…
- Trial name
- NCT04904510
- Testing
- INDICAID™ COVID-19 Rapid Antigen Test
- Where
- United States
- Volunteers
- 297 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Scars
Rapidly Absorbable Versus Non-absorbable Sutures for Mohs Surgery Repair on the Face: a Randomized Controlled Split-scar Study
This study aims to compare scar outcomes between rapidly absorbable and non-absorbable sutures (stitches) for the closure of wounds after skin cancer removal on the face.
- Trial name
- RAVNAS (NCT01932359)
- Testing
- rapidly absorbable suture (Vicryl Rapide), non-absorbable suture (Ethilon)
- Where
- Canada
- Volunteers
- 105 people
- Sponsor
- University of British Columbia
Intracranial Aneurysm
Success in Comaneci-assist Coils Embolization Surveillance Study (SUCCESS)
The Comaneci Embolization Assist Device is indicated for use in the neurovasculature as a temporary endovascular device used to assist in the coil embolization of wide-necked intracranial aneurysms with a neck width ≤ 10 mm.
- Trial name
- NCT04518670
- Testing
- Comaneci Embolization Assist Device
- Where
- 8 sites in United States
- Volunteers
- 90 people
- Sponsor
- Rapid Medical
Mild Cognitive Impairment, Lewy Body Dementia, Parkinson's Disease Rapid Eye Movement Sleep Behavior Disorder, Parkinson's Disease Dementia
A Study of Clenbuterol (CST-103) Co-administered With Nadolol (CST-107) in Subjects With Neurodegenerative Disorders
This is a Phase II, randomized, placebo-controlled, double-blind, crossover study on the CNS and pharmacodynamic effects of clenbuterol (CST-103) co-administered with nadolol (CST-107) in 4 subject populations with…
- Trial name
- CLIN-011 (NCT04739423)
- Where
- 7 sites in Australia, New Zealand and 1 more
- Volunteers
- 41 people
- Sponsor
- CuraSen Therapeutics, Inc.
Intracerebral Hemorrhage
Rapid Evacuation and Access of Cerebral Hemorrhage Registry
The goal of this observational study is to quantify the real-world effect of minimally invasive surgery (MIS) in patients with acute spontaneous supratentorial intracerebral hemorrhage.
- Trial name
- REACH (NCT07651631)
- Where
- United States
- Volunteers
- 2,500 people
- Sponsor
- Emory University
Lung Cancer
Partial Pressure of Oxygen Control Method in Identification of Intersegmental Plane
In recent years, an increasing number of pulmonary nodules have been detected through CT screening. The traditional surgical method for lung cancer is lobectomy combined with lymph node dissection.
- Trial name
- NCT06644066
- Testing
- Partial pressure of Oxygen Control method
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Tang-Du Hospital
Community-acquired Pneumonia
Use of a Rapid Diagnostic Test for Antibiotic De-escalation in Severe Community Acquired Pneumonia
The purpose of this study is to conduct an open-label step-wedge pilot clinical trial to compare an antibiotic strategy based on routine use of a novel rapid diagnostic test to usual care in critically ill adults with severe…
- Trial name
- BioFire (NCT04781829)
- Testing
- BioFire Pneumonia Panel
- Sponsor
- Northwestern University
Breast Neoplasms
Effects of Rapid Genetic Counseling and Testing in Newly Diagnosed Breast Cancer Patients
5-10% of breast cancer patients carry a mutation in the BRCA1 or BRCA2 gene. Genetic counseling and DNA testing are usually offered to selected patients after primary treatment has been completed (e.g.
- Trial name
- TIME (NCT00783822)
- Testing
- RGCT
- Where
- Netherlands
- Volunteers
- 265 people
- Sponsor
- The Netherlands Cancer Institute
Respiratory Virus Infection, Fever of Unknown Origin
Rapid Viral Diagnostics in Adults to Reduce Antimicrobial Consumption and Duration of Hospitalization
Viral respiratory infections are common and often require use of health care resources. Patients receive inappropriate bacterial antibiotics, which has many problems including side-effects, development of resistance and costs.
- Conditions
- Respiratory Virus Infection, Fever of Unknown Origin, Dyspnea, Chest Pain
- Trial name
- NCT02538770
- Testing
- Rapid diagnostics using Anyplex TMII RV16 Detection, Delayed diagnostics Anyplex TMII RV16 Detection
- Where
- 2 sites in Finland
- Volunteers
- 900 people
- Sponsor
- University of Oulu
HIV Infections
Rapid HIV Testing for Emergency Department Patients
The purpose of this study is to test data collection options in emergency departments (EDs) and to enhance ED patient awareness of the risk of HIV infection.
- Trial name
- NCT00676481
- Testing
- HIV risk education
- Where
- United States
- Volunteers
- 570 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Acid Base Disorder
Rapid Diagnostics for Genetic Disorders in Neonates
The goal of this study is to test a prototype genomic blood analysis for identifying rare diseases in infants hospitalized in the neonatal intensive care unit (NICU).
- Trial name
- NCT07005700
- Testing
- Targeted genomic sequencing
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Sharp HealthCare
Pneumonia, Methicillin-Resistant Staphylococcus Aureus
Trial of MRSA Polymerase Chain Reaction for Pneumonia
The purpose of this study is to conduct a randomized clinical trial to compare an antibiotic strategy based on a novel diagnostic test, polymerase chain reaction (PCR) to usual care, in critically ill adults with pneumonia…
- Trial name
- NCT02660554
- Testing
- Polymerase Chain Reaction (PCR)
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Northwestern University
Cleft Lip and Palate, Maxillary Expansion
Effectiveness of Two Maxillary Expanders in Improving the Transverse Skeletal and Dental Dimensions in Patients With Cleft Lip and Palate
This randomized controlled trial is designed to compare between quadlelix appliance vs hyrax expander regrading the their effectiveness in maxillary expansion in patients with cleft.
- Trial name
- NCT04331977
- Testing
- Maxillary Expansion
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Joint Arthrodesis, Joint Fixation
The SpeedPlate™ Rapid Compression Implant Study (The SPRINT™ Study)
Post-market, observational, multicenter, unblinded, ambidirectional cohort study to evaluate outcomes of study participants treated with the SpeedPlate™ product.
- Trial name
- SPRINT™ (NCT06548581)
- Testing
- SpeedPlate™ Rapid Compression Implants
- Where
- 5 sites in United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Treace Medical Concepts, Inc.
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