Clinical trials: Rapid Diagnosis
Pneumonia, Bacterial
Rapid De-escalation of Anti-MRSA Therapy Guided by S. Aureus Nares Screening in Case of Pneumonia
The current IDSA/ATS guidelines recommend Linezolid and Vancomycin for MRSA coverage in hospitalized patients with pneumonia, which is common clinical practice in Italy.
- Trial name
- SNAP (NCT06238297)
- Testing
- MRSA nasal swab based de-escalation
- Where
- Italy
- Volunteers
- 76 people
- Sponsor
- University of Bari Aldo Moro
Diabetes type1, Diabetes Mellitus, Type 1
Pilot of Pragmatic Delivery of Behavioral Approaches to Reduce Diabetes Distress in Adults With Type 1 Diabetes
This study is designed to test the feasibility and acceptability of behavioral approaches to reduce diabetes distress ("the expected burdens, concerns, fears, and threats that arise from the challenges of living with diabetes")…
- Conditions
- Diabetes type1, Diabetes Mellitus, Type 1, Diabetes, Autoimmune, Diabetes Mellitus
- Trial name
- ChargeUp (NCT06405386)
- Testing
- ReCharge, TakeCharge
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of North Carolina, Chapel Hill
Bipolar II Disorder, Major Depressive Episode
Open-Label Study of Geodon in Non-Rapid Cycling Bipolar II Patients With Major Depression
The purpose of this study is to evaluate the antidepressant effectiveness of Geodon for the treatment of patients diagnosed with Bipolar II disorder who are currently experiencing a major depressive episode.
- Trial name
- NCT00237666
- Testing
- Ziprasidone
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- The Medical Research Network
Diffuse Cutaneous Systemic Sclerosis
A Safety and Efficacy Study of FCR001 in Adults With Rapidly Progressive Diffuse Cutaneous Systemic Sclerosis
This is a multicenter, open-label study to evaluate the safety and tolerability and explore the efficacy of FCR001 cell therapy in adults with rapidly progressive Diffuse Cutaneous Systemic Sclerosis (dcSSc) at risk for organ…
- Trial name
- FREEDOM-3 (NCT05098145)
- Testing
- FCR001
- Where
- United States
- Sponsor
- Talaris Therapeutics Inc.
Penicillin Allergy, Hypersensitivity, Immediate
Risk-stratified Testing for Safe Removal of Penicillin Allergy Labels
The aim of this clinical trial is to analyze the negative predictive capacity and safety of risk-stratified direct drug provocation tests for patients with self-reported penicillin allergies.
- Conditions
- Penicillin Allergy, Hypersensitivity, Immediate, Hypersensitivity, Delayed, Hypersensitivity Response
- Trial name
- NCT06755281
- Testing
- Direct Oral challenge, standard of care
- Where
- 2 sites in Germany
- Volunteers
- 100 people
- Sponsor
- Deniz Göcebe
Neutropenic Fever
Fast-track Blood Test for Suspected Fever by Deficiency of a Kind of White Blood Cells As Main Defense Against Infection
This is a comparative study for adult participants with cancer who are suspected to have neutropenic fever (or fever with low neutrophil count) in emergency department.
- Trial name
- FRANCiS-NF (NCT05393505)
- Testing
- Meropenem Injection, Levofloxacin, Amoxicillin Clavulanate
- Where
- Hong Kong
- Volunteers
- 344 people
- Sponsor
- The University of Hong Kong
Focus is on Preoperative Psychiatric Charactarization of Elective Fast-track Hip and Knee Arthroplasty Patients
Psychiatric Disorder and Postoperative Morbidity in Hip and Knee Artroplasty
It has been established that patients with psychiatric disorders tend to do worse in a surgical setting. Some types of surgery with greater impact than others, including orthopedic surgery.
- Trial name
- NCT02576405
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Post Traumatic Stress Disorder, Sleep Disorder
Study of the Correlation Between Post-traumatic Stress Disorder and Paradoxical Sleep Behavior Disorder
Post-Traumatic Stress Disorder is a psychiatric disorder that occurs after a traumatic event and is estimated to affect 5 to 12% of the general population.
- Trial name
- TRAUMA-TCSP (NCT06221865)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Clermont-Ferrand
Pelvic Floor Muscle Electrophysiologic Therapy, Fast-Track Surgery
Effect of Pelvic Floor Muscle Electrophysiologic Therapy on Enhanced Recovery After Gynecologic Surgery
This study is to evaluate the effect of pelvic floor muscle electrophysiologic therapy on enhanced recovery after gynecologic surgery,to solve muscle soreness and retention of urine after laparoscopy, and endometrial repair after…
- Trial name
- NCT03524807
- Testing
- Electrophysiologic therapy
- Where
- China
- Volunteers
- 180 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Type 1 Diabetes
Evaluation of Gut Absorption Rate of Glucose After a Large Evening Meal in Type 1 Diabetes
Eight adolescent and young adult subjects with type 1 diabetes, age 16-24 years, will be recruited for this study on the basis of informed consent.
- Trial name
- NCT02782195
- Volunteers
- 16 people
- Sponsor
- University of Cambridge
Paroxysmal Atrial Fibrillation.
Atrial Fibrillation: Ablation or Surgical Treatment II: FAST II
The purpose of this study is to compare two invasive treatments of symptomatic paroxysmal atrial fibrillation: Percutaneous radiofrequency catheter ablation and mini invasive thoracoscopic radiofrequency ablation in patients…
- Trial name
- NCT01336075
- Testing
- Percutaneous radiofrequency catheter ablation, Mini invasive thoracoscopic radiofrequency ablation
- Where
- 3 sites in Denmark, Netherlands
- Volunteers
- 26 people
- Sponsor
- Aalborg University Hospital
Non-small Cell Lung Cancer (NSCLC)
ROSE for Improved Molecular Marker Testing Via EBUS
This research study is being done to compare two ways to conduct bronchoscopic biopsy of lymph nodes and other structures in the chest (i.e.
- Trial name
- ROSE/NoROSE (NCT04945317)
- Testing
- ROSE (presence of cytotech) & liquid prep, NO-ROSE (absence of cytotech) & liquid prep, ROSE (presence of cytotech) & tissue clot sample
- Where
- 4 sites in United States
- Volunteers
- 349 people
- Sponsor
- Johns Hopkins University
Diabetes Mellitus, Type 1
A Research Study Looking at How Faster Aspart Injected in Double Concentration Works in the Body of People With Type 1 Diabetes Mellitus
This study is looking at how five different formulations of faster aspart 200 U/mL reach and stay in the blood after injection. The purpose is to find a formulation that behaves similarly to the reference product called faster…
- Trial name
- NCT03723759
- Testing
- Faster Aspart 200 U/mL, Faster aspart 100 U/mL
- Where
- Germany
- Volunteers
- 56 people
- Sponsor
- Novo Nordisk A/S
Severe Pneumonia
Rapid Identification of Infectious Pathogens in Severe Pneumonia Guided by Bronchoscopic Imaging and Lung CT
Severe pneumonia requires rapid and accurate diagnosis for targeted treatment, but single lung CT has limitations in identifying pathogens and distinguishing infectious/non-infectious etiologies.
- Trial name
- IMG-GUIDE-IP (NCT07308340)
- Testing
- Standalone Lung CT for Severe Pneumonia Diagnosis, Bronchoscopic Imaging + Lung CT for Severe Pneumonia diagnosis
- Volunteers
- 400 people
- Sponsor
- The First Hospital of Jilin University
Coronary Artery Disease
Fast Assessment of STenosis Severity- FASTII Study
The Multicenter FAST (Fast Assessment of STenosis severity) study is a prospective observational multicenter study designed to evaluate the diagnostic accuracy of offline 3D-QCA based FFR, using CAAS Workstation (Pie Medical…
- Trial name
- FASTII (NCT03791320)
- Testing
- Vessel Fractional Flow Reserve
- Where
- 6 sites in United States, France and 4 more
- Volunteers
- 330 people
- Sponsor
- Erasmus Medical Center
Malaria
Can Treatment of Malaria be Restricted to Parasitologically Confirmed Malaria?
The investigators performed a prospective study, in order to assess the feasibility and safety of restricting antimalarials to rapid diagnostic test (RDT)-confirmed cases in children aged 5 to 15 years-old
- Trial name
- NCT00913146
- Where
- Benin
- Volunteers
- 484 people
- Sponsor
- Institut de Recherche pour le Developpement
FAST Scan
Clinical Feasibility of Full Free-Breathing Cardiac Magnetic Resonance Imaging
To evaluate the feasibility, efficiency, and diagnostic concordance of a full comprehensive free-breathing cardiac magnetic resonance protocol with motion correction and sensing.
- Trial name
- NCT07395843
- Testing
- Free-breathing CMR
- Where
- China
- Volunteers
- 605 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Gastroenteritis
Acute Gastroenteritis: Development of PCR Analysis and Algorithm for Fast Clarification of Isolation Indication
Isolation of contagious patients is expensive, requires more caregiver time, most of the patients perceive isolation as a mental strain and it has been shown that the level of care and observation is lower than in a normal ward.
- Trial name
- NCT02685527
- Where
- Denmark
- Volunteers
- 285 people
- Sponsor
- University of Southern Denmark
PTSD
Rapid Acceleration Process for Intensive Treatment of PTSD in 5 Days
Veterans with posttraumatic stress disorder (PTSD) need more effective treatments. Existing options can have limited adherence and can be very time-consuming. As such, alternative interventions are needed.
- Trial name
- RAPID5 (NCT07167940)
- Testing
- Transcranial magnetic stimulation
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- VA Office of Research and Development
Obstructive Sleep Apnea
Assessment of the Impact on the Quality of Life of Surgically Assisted Maxillary Expansion in Adult Patients Followed for Obstructive Sleep Apnea Syndrome
The research aims to assess the impact on quality of life of surgically maxillary expansion in adult patients followed for obstructive sleep apnea syndrome.
- Trial name
- QUAVIMAX (NCT04618991)
- Testing
- Filling the Quebec Sleep Questionnaire
- Where
- France
- Volunteers
- 9 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
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