Clinical trials: Rapid Diagnosis
Cutaneous Leishmaniases
Cutaneous Leishmaniasis Diagnostic Study
The performance of the CL Detect Rapid test will be tested in individuals with suspected cutaneous leishmaniasis in Ethiopia using both skin slit and dental broach samples against a combined reference of microscopy and PCR.
- Trial name
- NCT03837431
- Testing
- Skin slit, Dental broach, Tape disc
- Where
- Ethiopia
- Volunteers
- 351 people
- Sponsor
- Institute of Tropical Medicine, Belgium
Stroke
Effectiveness, Safety and Ease of Application of Excel Cryo Cooling Collar to Rapidly Reduce Core Brain Temperature
Research has shown that lowering brain temperature may have good results in heart attack patients. Lowering brain temperature may be a promising treatment for stroke patients.
- Trial name
- CryoCollar (NCT02703675)
- Testing
- Excel Cryo Cooling Collar
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Michel Torbey
Pleural Effusion, Malignant, Ascites, Malignant
Mass Response of Tumor Cells as a Biomarker for Rapid Therapy Guidance (TraveraRTGx)
The primary objective of this study, sponsored by Travera Inc. in Massachusetts, is to validate whether the mass response biomarker has potential to predict response of patients to specific therapies or therapeutic combinations…
- Conditions
- Pleural Effusion, Malignant, Ascites, Malignant, Carcinoma, Carcinoma, Hepatocellular
- Trial name
- TraveraRTGx (NCT05461430)
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Travera Inc
Lung Cancer (NSCLC), Perioperative Care
Mobilization Before and After Video-Assisted Thoracoscopic Surgery Lobectomy/Segmentectomy
To examine mobilization before/after Video-Assisted Thoracoscopic Surgery Lobectomy/Segmentectomy and further assess possible barriers to mobilization.
- Conditions
- Lung Cancer (NSCLC), Perioperative Care, Enhanced Recovery After Surgery
- Trial name
- NCT07338474
- Where
- Denmark
- Volunteers
- 51 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Hypersensitivity, Coronary Artery Disease
Physiopathology of Rapid Aspirin Desensitization
Aspirin is very effective in protecting patients with coronary artery disease against adverse cardiac events, because it is a potent "antiplatelet agent".
- Trial name
- NCT01118546
- Where
- France
- Volunteers
- 86 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Bipolar Disorder, Involutional Depression
Omega-3 Fatty Acids in the Treatment of Bipolar Disorder: A Double-Blind, Placebo-Controlled Trial
This study will examine the effectiveness of omega-3 fatty acids, compounds found in plants and fish, in treating bipolar disorder. Some studies have indicated that omega-3 fatty acids may be effective in treating mood disorders.
- Conditions
- Bipolar Disorder, Involutional Depression, Mood Disorder
- Trial name
- NCT00001146
- Testing
- Ethyl Eicosapentaenoic Acid, OmegaBrite
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- National Institute of Mental Health (NIMH)
Aortic Aneurysm
Fast Track Management in Elective Open Infrarenal Aortic Aneurysm Repair
Fast track programs have been introduced in many surgical fields to minimize postoperative morbidity and mortality. Morbidity after elective open infrarenal aneurysm repair is as high as 30%, mortality ranges up to 10%.
- Trial name
- NCT00615888
- Testing
- Fast track patient management, Traditional management
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University of Ulm
Chronic Kidney Disease
Simplified Rapid Hydration in Preventing CA-AKI Among Patients With Chronic Kidney Disease
No well-defined protocols exist to guide fluid administration for prevention of contrast-associated acute kidney injury in high risk patients.
- Trial name
- TIME (NCT02232997)
- Testing
- Standard Hydration, Simplified Hydration
- Where
- China
- Volunteers
- 1,002 people
- Sponsor
- Guangdong Provincial People's Hospital
Prostate Cancer, Multiparametric MRI
Deep Learning Super Resolution Reconstruction for Fast and Motion Robust T2-weighted Prostate MRI
The aim of this study was therefore to investigate a new unrolled DL super resolution reconstruction of an initially low-resolution Cartesian T2 turbo spin echo sequence (T2 TSE) and compare it qualitatively and quantitatively to…
- Trial name
- NCT05820113
- Testing
- Deep learning based reconstruction of T2-TSE sequence
- Where
- Germany
- Volunteers
- 109 people
- Sponsor
- University Hospital, Bonn
Sepsis, Septicemia
A Rapid Diagnostic of Risk in Hospitalized Patients Using Machine Learning
In this study, the investigators will deploy a software-based clinical decision support tool (eCARTv5) into the electronic health record (EHR) workflow of multiple hospital wards.
- Conditions
- Sepsis, Septicemia, Respiratory Failure, Hemodynamic Instability
- Trial name
- NCT05893420
- Testing
- eCARTv5 clinical deterioration monitoring, Standard of care control
- Where
- 3 sites in United States
- Volunteers
- 30,000 people
- Sponsor
- AgileMD, Inc.
Tuberculosis
Development of a Rapid and Accurate Diagnostic Assay for Tuberculosis
This study evaluates new technique for diagnosis of tuberculosis. Among patients who are suspected with tuberculosis, participants will be tested conventional method including Xpert TB/RIF assay, and new diagnostic technique…
- Trial name
- NCT03423550
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- Asan Medical Center
Dentin Hypersensitivity
Efficacy of Dissolvable Mineral Loaded Starch Particles Strips in Providing Rapid Relief of Dentin Hypersensitivity: A Randomized Clinical Trial
Dentinal Hypersensitivity is a common condition associated with exposed root surfaces that causes short, sharp pain in response to thermal, evaporative, or tactile stimuli, negatively affecting patients' daily activities and oral…
- Trial name
- NCT07669818
- Testing
- dissolvable mineral-loaded starch particle strips, Novamin containing toothpaste
- Where
- Egypt
- Volunteers
- 82 people
- Sponsor
- Cairo University
Emergency
Rapid Sequence Intubation at the Emergency Department
All patients undergoing emergent endotracheal intubation (RSI) at the Emergency Department will be screened for inclusion in this clinical study.
- Trial name
- NCT02297113
- Testing
- Macintosh blade, C-MAC videolaryngoscope
- Where
- Switzerland
- Volunteers
- 150 people
- Sponsor
- University of Zurich
Out-Of-Hospital Cardiac Arrest
Rapid Response VA-ECMO in Refractory Out-of-hospital Cardiac Arrest
A selected group of patients with refractory cardiac arrest may benefit from inhospital treatment and this may warrant transfer to the hospital with ongoing CPR.
- Trial name
- RESuSCITATe (NCT03658759)
- Testing
- Extracorporeal Cardiopulmonary Resuscitation
- Where
- Netherlands
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Sars-CoV-2 Infection
Clinical Evaluation of the SONA Saliva C-19 Rapid Self-Test for the Detection of COVID-19
The Sona Saliva C-19 Rapid Self-Test is a lateral flow assay intended for detection of the SARS-CoV-2 virus. Performance of the Sona Saliva C-19 Rapid Test assay will be assessed by comparison to an RT-PCR reference method.
- Trial name
- NCT05256589
- Testing
- Sona Saliva C-19 Rapid Self-test
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- Sona Nanotech Inc
Rheumatoid Arthritis
The Effect of Certolizumab Pegol on MRI Synovitis and Bone Edema in Rheumatoid Arthritis Patients
The purpose of this study is to determine whether Certolizumab pegol can rapidly reduce the inflammatory changes and inhibit erosions on hand and wrist MRI in patients with active moderate to severe rheumatoid arthritis.
- Trial name
- PICS (NCT01213017)
- Testing
- certolizumab pegol
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Oklahoma Medical Research Foundation
Alzheimer's Disease, Dementia
Safety and Efficacy of High Dose, Rapid Titration Galantamine in Patients With Alzheimer's Disease
The purpose of this study was to determine the safety and effectiveness of a relatively high dose of galantamine, 32 mg /day in a three-times daily dosage, compared with placebo in treating patients with Alzheimer's disease.
- Trial name
- NCT00338117
- Testing
- Galantamine hydrobromide
- Volunteers
- 554 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Stroke, Health Knowledge, Attitudes, Practice
Improving Parent Sign-Up for a Children's Stroke Awareness Program
Many families do not sign up for a school-based stroke awareness program (FAST Heroes) that teaches children and parents to recognize stroke symptoms and act quickly.
- Trial name
- NCT07745582
- Testing
- Printed Letter, E-mail Invitation, E-mail Invitation Plus Teacher Feedback
- Where
- Greece
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Macedonia
Atrial Fibrillation, Atrial Flutter
Intravenous Tedisamil in the Rapid Conversion of Atrial Fibrillation or Flutter to Normal Sinus Rhythm in Male Subjects
The purpose of this study is to demonstrate the ability of tedisamil to convert atrial fibrillation or flutter into normal sinus rhythm (NSR) in male patients.
- Trial name
- NCT00126061
- Testing
- Tedisamil sesquifumarate
- Where
- 26 sites in United States, Czechia and 3 more
- Sponsor
- Solvay Pharmaceuticals
Myocardial Infarction
Rapid Activity of Platelet Inhibitor Drugs Study 2
The aim of the RAPID study is to evaluate the superiority rapid onset of action of Ticagrelor 360 mg LD versus Prasugrel 60 mg LD, in 50 patients with STEMI (ST segment elevation myocardial infarction) undergoing PPCI with…
- Trial name
- NCT01805570
- Testing
- Prasugrel, Ticagrelor
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- David Antoniucci
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