Clinical trials: Rapid Sequence Intubation
Intubation; Difficult or Failed
Comparison of Ultrasound Techniques for Assessment of Endotracheal Tube Placement
This study is a single-center, randomized clinical trial conducted in an emergency department on intubated patients with rapid sequence intubation.
- Trial name
- NCT06656546
- Testing
- Tracheal Ultrasound, Lung Ultrasound, Diaphragm Ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Emergencies
Evaluation of Effectiveness of Two Different Doses of Mivacurium in Rapid Sequence Intubation
Mivacurium can be considered as an optimal choice for muscle relaxation in short duration surgeries, as butyrylcholinesterase can rapidly and reliably degrade this benzylisoquinoline muscle relaxant in vivo.
- Trial name
- RSI (NCT06072534)
- Testing
- "Mivacurium Chloride"
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Al-Azhar University
Intubation, Oxygen Inhalation Therapy
Pre- and Apnoeic Oxygenation for RSI in ED
Critically ill patients may need support for breathing by means of intubation, which is placement of a breathing tube into the windpipe.
- Trial name
- Pre-AeRATE (NCT03396094)
- Testing
- High-flow nasal cannulae (HFNC) oxygenation, Non-rebreather mask and standard nasal cannula
- Where
- Singapore
- Volunteers
- 192 people
- Sponsor
- National University Hospital, Singapore
Emergencies, Out-of-hospital Setting
Optimisation Strategy for Emergency Tracheal Intubation
This study has to objective to assess, in adults' patients needing tracheal intubation because of vital distress, the effect of a combined strategy to reduce intubation-related morbidity.
- Conditions
- Emergencies, Out-of-hospital Setting, Tracheal Intubation
- Trial name
- OSETIM (NCT05539391)
- Testing
- Data patient, Physical examination, Rapid sequence intubation (RSI) : Rocuronium /Bag-mask ventilation /GEB
- Where
- 22 sites in France
- Volunteers
- 1,500 people
- Sponsor
- University Hospital, Bordeaux
Rapid Sequence Induction and Intubation, Rocuronium
Comparison of Standard rapi̇d Sequential Intubation Protocol With Rocuronium in Emergency Department
Airway management and advanced airway management are the issues that are applied every day in emergency services and that the emergency physician should know best.
- Trial name
- NCT05343702
- Testing
- priming with rocuronium
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Respiratory Failure
HEAVEN Criteria: Prediction of Difficult Airway for In- Hospital Emergency Airway Management
The HEAVEN criteria were found valid to predict difficult airways during preclinical emergency intubations in a retrospective study.
- Trial name
- NCT04764799
- Testing
- Rapid sequence induction
- Where
- Switzerland
- Volunteers
- 2,800 people
- Sponsor
- Thomas Riva
Post-Traumatic Stress Disorder, Acute Respiratory Failure
Effect of Ketamine and Etomidate During RSI on Long Term Outcomes
The RSI-LTO study collects long-term outcomes from the RSI trial (NCT05277896). One-third of adults who are intubated in the ED or ICU experience symptoms of posttraumatic stress disorder (PTSD).
- Trial name
- RSI-LTO (NCT06179485)
- Testing
- Ketamine, Etomidate
- Where
- 6 sites in United States
- Volunteers
- 1,756 people
- Sponsor
- Vanderbilt University Medical Center
Tracheal Intubation Morbidity
Comparison of Intubation Duration Between Rapid Sequence Intubation (RSI) Technique and Non-RSI Technique
The purpose of this study is to evaluate intubation duration between rapid sequence intubation technique (RSI) and non-rapid sequence intubation technique (non-RSI) performed by emergency medicine residents in Siriraj hospital.
- Trial name
- NCT01474252
- Testing
- RSI
- Where
- Thailand
- Volunteers
- 224 people
- Sponsor
- Siriraj Hospital
Intubation Conditions
Intubating Conditions During Rapid Sequence Induction in Elderly With Either Suxamethonium 1.0 mg/kg or Rocuronium 1.0 mg/kg
The aim of this study is to determine the proportion of excellent tracheal intubation conditions at 60 seconds after administration of either rocuronium 1.0 mg/kg or suxamethonium 1 mg/kg in patients with age ≥ 80 years during…
- Trial name
- NCT04868409
- Testing
- Suxamethonium, Rocuronium
- Where
- 4 sites in Denmark
- Volunteers
- 102 people
- Sponsor
- Matias Vested
Rapid Sequence Induction Intubation
Effect of Cricoid Pressure on Macintosh, McGrath X-Blade and Glidescope Videolaryngoscopes in Rapid Sequence Induction Intubation
Non- Fasted patients need rapid sequence intubation. The investigators aimed to compare the intubation times of Macintosh , and McGrath X-Blade or Glidescope in these Ascenario.
- Trial name
- NCT02588157
- Testing
- Macintosh, Glidescope, McGrath MAC X-Blade
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Kocaeli University
Rapid Sequence Induction, Rapid Sequence Intubation
Rapid Sequence Intubation With Rocuronium in Elderly Patients
With the prolongation of life expectancy, the frequency of surgical intervention and anesthesia increases in elderly patients. The rapid Sequence Intubation(RSI) technique is preferred in patients with aspiration risk and who…
- Conditions
- Rapid Sequence Induction, Rapid Sequence Intubation, Rocuronium
- Trial name
- NCT05067829
- Testing
- Train of four(TOF)
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Ankara City Hospital Bilkent
Trauma, Shock, Traumatic
Comparison of Ketamine and Etomidate During Rapid Sequence Intubation in Trauma Patients
In trauma patients with high shock index, the investigators compare the effects on hemodynamics between ketamine and etomidate.
- Trial name
- NCT04120870
- Testing
- Etomidate Injection 0.2 mg/kg, Ketamine injection 2 mg/kg
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- Ajou University School of Medicine
Easy of Laryngoscopy Manipulation, Vocal Cord Position or Movement
Intubating Condition After Magnesium Pre-treatment
Magnesium had an inhibitory effect on neuromuscular transmission and caused a decrease in muscle fiber membrane excitability. It reduces the amount of acetylcholine that is released at the motor nerve terminal by decreasing the…
- Conditions
- Easy of Laryngoscopy Manipulation, Vocal Cord Position or Movement, Patient Reaction to Intubation and Cuff Inflation, Mean Arterial Pressure
- Trial name
- NCT01153256
- Testing
- magnesium sulphate, normal saline
- Where
- South Korea
- Volunteers
- 168 people
- Sponsor
- Seoul National University Bundang Hospital
Rapid Sequence Intubation
Pre-oxygenation With Real Time End-tidal Oxygen Measurements Versus Single Breath Measurements
This study examines the performance of a nasal cannula end-tidal oxygen (EtO2) measurement as compared to the gold standard of single breath end-tidal oxygen measurements in healthy volunteers.
- Trial name
- NCT03840486
- Testing
- Non-rebreather mask (NRBM), Non-invasive ventilator mask (NIV), Nasal cannula EtO2 sensor
- Where
- 2 sites in United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Emory University
Anesthesia
Comparison of Intubation Conditions During Rapid Sequence Induction Obtained With Modified Time Principal Induction With a Standard Intubation Dose of Rocuronium Versus Succinylcholine
The purpose of this study is to assess and compare conditions for tracheal intubation obtained with modified time principal induction with 0.6 mg/kg rocuronium and 1 mg/kg succinylcholine.
- Trial name
- NCT06029049
- Testing
- Modified Time Principle Induction (MTPI) with rocuronium, RSI succinylcholine
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- The University of Texas Health Science Center, Houston
Intubation Complication
End-tidal Oxygen Can Reliably Predict the Arterial Partial Pressure of Oxygen Among Emergency Department Patients
Recent studies have shown that end tidal oxygen (ETO2) monitoring can be useful to determine the adequacy of preoxygenation. No study has assessed the correlation between ETO2 values obtained during preoxygenation to predict the…
- Trial name
- NCT03842306
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- New York City Health and Hospitals Corporation
Apneic Oxygenation
A "Less-rapid" Sequence Anesthetic Induction/Intubation Sequence? Does Apneic Oxygenation by Means of an Oxygenating Laryngoscope Blade Prolong the "Duration of Apnea Without Desaturation" in Paralyzed Non-obese and Morbidly Obese Patients?
The study will test the efficacy of the Pentax AWSTM video laryngoscope (VLS) equipped with a P Blade (Figure 1) as the means to provide Apneic Oxygenation (AO) and prolong Duration of Apnea Without Desaturation (DAWD) in…
- Trial name
- NCT02943629
- Testing
- Apneic oxygenation: Eight minute, Without apneic oxygenation, Apneic oxygenation: five minutes
- Sponsor
- Vanderbilt University
Intubation; Difficult
Ketamine Versus Etomidate During Rapid Sequence Intubation: Consequences on Hospital Morbidity
The expected benefit is a reduction of the morbidity of patients admitted in the intensive care unit having received ketamine for intubation.
- Trial name
- KETASED (NCT00440102)
- Testing
- Ketamine, Etomidate
- Where
- France
- Volunteers
- 655 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Airway Control, Anesthesia
Ketamine Versus Etomidate for Rapid Sequence Intubation
The purpose of this study is to compare the effectiveness and safety of ketamine and etomidate during rapid sequence intubation (RSI).
- Conditions
- Airway Control, Anesthesia, Intubation, Complication
- Trial name
- NCT01823328
- Testing
- Ketamine, Etomidate
- Where
- United States
- Volunteers
- 143 people
- Sponsor
- Hennepin Healthcare Research Institute
Rapid Sequence Induction
Impact of Opioids on Heart Rate During Rapid Sequence Intubation
The patient is seen upstream by an anaesthetists resuscitator (MAR) in order to carry out his anesthesia consultation. If the patient meets the eligibility criteria he will be informed of the study and his signed consent will be…
- Trial name
- CANDY-CRASH (NCT05384665)
- Testing
- Remifentanil, Sufentanil
- Where
- France
- Volunteers
- 3 people
- Sponsor
- Centre Hospitalier Sud Francilien