Clinical trials: Reaching
Old Age; Debility, Peripheral Neuropathy
Protective Arm Balance Responses
The overall objective of this study is to investigate the effect of attention control training on reach-grasp stabilizing responses during fall-induced perturbations.
- Trial name
- PAT (NCT06388434)
- Testing
- Protective Arm Balance Response Training
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Phase 1, Bioavailability
A Study to Compare How Much Solifenacin Succinate and Mirabegron Reach the Blood When Administered Together as Fixed-dose Combination Tablets and With Single Individual Tablets of the Same Medications at Three Dose Levels
This study compares the pharmacokinetics (PK), safety and tolerability of fixed dose combination (FDC) tablets containing solifenacin succinate and mirabegron with the co-administration of single entity tablets (SET), at three…
- Conditions
- Phase 1, Bioavailability, Healthy Subjects
- Trial name
- NCT02010944
- Testing
- solifenacin succinate, mirabegron, mirabegron/solifenacin succinate
- Where
- Germany
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Europe B.V.
Dementia
Implementation Study of Dementia Guidelines in Primary Care
The purpose of this study is to determine whether a specially developed Dementia Training Program for duos of general practitioners and primary care nurses is able to increase the number dementia diagnoses in elderly people…
- Trial name
- NCT00459784
- Testing
- Dementia Training Program
- Where
- Netherlands
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Chronic Condition, Chronic Conditions, Multiple
EMBOSS A Person-centred Integrated-care for Chronic Diseases in Patients of Low Socio Economic Status
People of low socio economic status (SES) more often than others suffer from chronic diseases like diabetes mellitus, chronic obstructive pulmonary disease (COPD), or coronary diseases.
- Trial name
- EMBOSS (NCT05972031)
- Testing
- Person-centred integrated care intervention
- Where
- Netherlands
- Volunteers
- 540 people
- Sponsor
- Radboud University Medical Center
Asthma
Real-world Effectiveness of Combination Therapies in Primary Care Asthma Management
To evaluate whether beclomethasone dipropionate / formoterol (BDP/FOR; Fostair® 100/6) is at least equivalent in terms of exacerbation prevention to fluticasone dipropionate / salmeterol (FP/SAL; Seretide® 125) in matched asthma…
- Trial name
- REACH (NCT01908075)
- Testing
- FP/SAL, BDP/FOR
- Volunteers
- 194,723 people
- Sponsor
- Research in Real-Life Ltd
Hemophilia A, Prophylaxis of Bleeding
Prophylaxis Regimen for Hemophilia A Patients
Researchers are looking for a better way to treat people who have hemophilia A. Hemophilia A is a genetic bleeding disorder that is caused by the lack of a protein in the blood called "clotting factor 8" (FVIII).
- Trial name
- PREDICT (NCT05036278)
- Testing
- Damoctocog alfa-pegol is a recombinant B-domain deleted human coagulation FVIII variant site specifically conjugated with a 60 kDa, branched (30 kDa each) polyethylene glycol (PEG).
- Where
- 12 sites in United States
- Volunteers
- 21 people
- Sponsor
- Bayer
Food Insecurity
Comparing the Effectiveness of Two Produce Prescription Approaches On Fruit and Vegetable Intake and Food Security, While Exploring Implementation Outcomes Such as Reach, Implementation, Sustainability, and Cost
The produce prescription program is one type of food is medicine (FIM) programs, where healthcare providers "prescribe" fruits and vegetables (F\&V) to patients with low household incomes, experience food insecurity, and one or…
- Trial name
- NutriConnect (NCT06263751)
- Testing
- Product prescription program- NutriConnect Credit, Product prescription program- NutriConnect Delivery
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Washington University School of Medicine
Obesity, Obesity, Childhood
In-home Obesity Prevention to Reach Low-income Infants
Existing obesity prevention efforts have had limited success among underserved, low-income children. This study capitalizes on the strengths of a nationwide ongoing Home Visitation Program (HVP), which serves at-risk, low-income…
- Conditions
- Obesity, Obesity, Childhood, Obesity; Familial
- Trial name
- NCT03529695
- Testing
- Standard HVP Curriculum, Obesity Prevention
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Stroke
Reaching in Stroke 3rd Phase
The project targets stroke survivors to investigate the effect of augmented feedback (using robotic force cues and visual feedback) and rewards (game scores), on their upper limb reaching patterns and trunk compensatory movements
- Trial name
- RISP3 (NCT02912923)
- Testing
- Visual + Force Feedback, Visual + Force + Game Scores Feedback
- Where
- Canada
- Volunteers
- 23 people
- Sponsor
- University of British Columbia
Meconium Obstruction of Prematurity
Saline Enema Administration in Meconium Obstruction of Prematurity and Impact on the Resolution, Feeds, Microbiome, and Gut-brain Axis.
The goal of this clinical trial is to study the effect of twice-daily saline enema (SE) in the treatment obstruction of prematurity (MOP) in infants with the birth weight ≤1.25kg.
- Trial name
- NCT06048614
- Testing
- Saline Enema (SE), Glycerin Suppository
- Where
- 2 sites in Singapore
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Stroke
The Effect of Resistance to Participant-Supported Reaching on Workspace of the Hand in Severe Chronic Stroke
Disturbances in movement coordination are the least well understood but often the most debilitating with respect to functional recovery following stroke.
- Trial name
- NCT01548781
- Testing
- Impairment-based robotic intervention for reaching function
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Northwestern University
Obesity
State-wide Health Approach to Increase Reach and Effectiveness: Study 2
Behavioral weight loss programs can successfully reduce body weight, but these programs are available to limited numbers of overweight and obese individuals.
- Trial name
- SHARE (NCT01560130)
- Testing
- Shape Up Rhode Island + Online weight loss program, Shape Up Rhode Island + Online weight loss program + Groups, Shape Up Rhode Island + Online weight loss + Incentives
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Hodgkin Lymphoma
ANIMATE: Phase II Study of Nivolumab Monotherapy for Relapsed/Refractory Hodgkin Lymphoma
This is a single-arm, phase II, multi-centre study of the safety and efficacy of the PD-1 inhibitor, nivolumab, as second-line or third-line salvage therapy as a bridge to stem cell transplant (SCT) in relapsed/ refractory…
- Trial name
- ANIMATE (NCT03337919)
- Testing
- Nivolumab
- Where
- 10 sites in United Kingdom
- Volunteers
- 78 people
- Sponsor
- University College, London
Multiple Sclerosis
The Reliability and Validity of the Functional Reach Test in Patients With Multiple Sclerosis
Loss of limits of stability ability is one of the major components of balance dysfunction in MS. The functional reach test is quick and clinically available tool for assessing limits of stability but reliability and validity of…
- Trial name
- NCT04185688
- Testing
- Functional Reach Test
- Where
- Turkey (Türkiye)
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Gazi University
Intervention, Wait List Control
Restoring Empowerment and Choosing Hope (REACH)
The goals of REACH are to help adults develop the skills they need to develop healthy relationship and marriage skills, improve ability to parent and co-parent effectively, identify and enhance skills and abilities required to…
- Trial name
- REACH (NCT05299138)
- Testing
- Marriage and Relationship Enhancement Skills (MRES) Intervention
- Where
- United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Jewish Family & Children's Service of the Suncoast, Inc.
Dementia Alzheimers
Alzheimer's Family Caregiver Intervention in Vietnam
This is a single arm pilot study of 6-8 families to test the feasibility and acceptability of a Alzheimer's family caregiver intervention in Vietnam.
- Trial name
- NCT03100617
- Testing
- Psychosocial caregiver intervention
- Where
- Vietnam
- Volunteers
- 6 people
- Sponsor
- University of California, Davis
Cannabis Abuse, Cannabis Dependence
The Teen Marijuana Check-Up
This behavioral research is an efficacy trial evaluating an intervention called "The Teen Marijuana Check-Up" with non-treatment seeking adolescent marijuana users.
- Trial name
- TMCU3 (NCT00350285)
- Testing
- Motivational enhancement therapy, Marijuana education
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- University of Washington
Systemic Sclerosis, SSc
Rehabilitation for Arm Coordination and Hand Movement in Systemic Sclerosis
The purpose of this study is to test two rehabilitation programs to improve arm function for patients with scleroderma. This is a Phase 2 randomized controlled trial in which participants will be assessed at baseline, 8 weeks…
- Trial name
- REACH (NCT03482219)
- Testing
- Occupational therapy, Home app intervention
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Michigan
Individuals With C6-C7 Tetraplegia (AIS A or B)
Grasping Rehabilitation Using Motor Imagery With or With no Neurofeedback After Tetraplegia
Motor imagery has shown promising results to optimize tenodesis grasp in individuals with C6-C7 tetraplegia. However, efficacy of using motor imagery to improve grasping after tetraplegia requires further study with higher level…
- Trial name
- TETRAMINF (NCT03190863)
- Testing
- Motor imagery combined with neurofeedback (MINF), Motor imagery (MI), Control (C)
- Where
- 2 sites in France
- Volunteers
- 21 people
- Sponsor
- Hospices Civils de Lyon
Diabetes Mellitus, Type 2
Self Titration With Apidra to Reach Target Study (START)
Primary Objective: The primary objective of this study is to demonstrate non-inferiority of a patient-managed titration algorithm (including blood glucose monitoring) for the addition of a single dose of insulin glulisine at…
- Trial name
- NCT01013571
- Testing
- insulin glargine, Apidra (insulin glulisine)
- Where
- Canada
- Volunteers
- 493 people
- Sponsor
- Sanofi