Clinical trials: Recession
Gingival Recession
Clinical Evaluation of Single-stage Advanced Versus Rotated Flaps in the Treatment of Gingival Recessions
BACKGROUND: Several procedures have been reported for the surgical correction of gingival recession (GR), including the laterally positioned flap (LPF) and the coronally advanced flap (CAF), performed as single or two-stage…
- Trial name
- NCT02433912
- Testing
- Test - Laterally positioned flap, Control-Coronally positioned flap, 750 mg paracetamol
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Alveolar Bone Loss, Gingival Recession
Xenogenic Collagen Matrix vs. Connective Tissue Graft for Soft Tissue Augmentation Around Early Maxillary Implants
This study compares two methods used to improve gingival tissue around dental implants placed in (the maxillary esthetic zone). After a tooth is removed and a dental implant is placed early (usually 4-8 weeks later), additional…
- Conditions
- Alveolar Bone Loss, Gingival Recession, Peri-implant Mucositis
- Trial name
- NCT07024186
- Testing
- Xenogeneic Collagen Matrix, subepithelial connective tissue graft
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Minia University
Gingival Recession
Areal and Linear Comparison of Gingival Recession
Recent advances in digital technology have led to the emergence of precise methods for measuring gingival recession and tissue thickness.
- Trial name
- agr (NCT06502782)
- Testing
- digital assesment
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Gingival Recessions, Gingival Recession, Mucogingival Surgery
Optimizing Clinical Outcomes in CAF + SCTG: the Impact of Compressive Sutures
This randomized controlled clinical trial aims to evaluate the additional effect on clinical outcomes of compressive sutures associated with coronally advanced flap (CAF) and subepithelial connective tissue graft (SCTG) for the…
- Conditions
- Gingival Recessions, Gingival Recession, Mucogingival Surgery, Suture
- Trial name
- NCT06701786
- Testing
- Compressive Sutures (CSs) group, Without Compressive Sutures (WCSs) group
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- G. d'Annunzio University
Gingival Recession, Localized
Ultrasonographic Evaluation of the Connective Tissue Grafts Obtained With Two Different Methods in Root Coverage
Gingival recession is a clinical problem that increases with age and affects patient comfort. It is defined as the displacement of the gingival margin to a more apical position of the cementum-enamel border of the tooth.
- Trial name
- NCT06373783
- Testing
- subepithelial connective tissue graft, de- epithelize gingival graft, ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Gingival Recession
Titanium Prepared Platelet Rich Fibrin for Multiple Gingival Recessions
Objective: Titanium-prepared platelet-rich fibrin (T-PRF) is activated with titanium, which results in a more mature and aggregated form than PRF.
- Trial name
- NCT03121872
- Testing
- Root Coverage Surgery with T-PRF, Root Coverage Surgery with CTG
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Gingival Recession
Expression of Angiogenic Biomarkers During Healing of Intra-Oral Soft Tissue Engineered Grafts
The purpose of this observational research study is to understand more about wound healing of gum tissue. This study was the biomarker study of a small cohort of study participants derived from NCT01547962 (completed).
- Trial name
- NCT01134081
- Testing
- CelTx™, Free Gingival Graft
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Michigan
Gingival Thickness
Soft Tissue Augmentation Using CAF With Either SCTG and Vitamin C Versus SCTG Alone in Management of RT1 Gingival Recession
Compare gingival thickness following CAF With SCTG and Vitamin C Versus SCTG Alone in Management of RT1 Gingival Recession.
- Trial name
- NCT04632693
- Testing
- CAF with SCTG and Vitamin C injection, CAF with SCTG alone
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hyaluronic Acid, Gingival Recession, Localized
Hyaluronic Acid and Free Gingival Graft Healing
This study aims to evaluate the impact of locally applied hyaluronic acid on free gingival graft wound bed healing and palatal donor site wound healing. Forty subjects will be randomly divided in two separate groups.
- Conditions
- Hyaluronic Acid, Gingival Recession, Localized, Pain, Postoperative
- Trial name
- NCT05990049
- Testing
- Hyadent BG
- Where
- Croatia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Dental Abrasion, Gingival Recession
Evaluation of Two Resin Composites and Two Adhesives for a Novel Restorative Protocol to Treat Cervical Lesions
Non-carious cervical lesion is frequently associated with gingival recession, resulting in a combined lesion that has a different treatment prognosis when the two lesions appear alone.
- Conditions
- Dental Abrasion, Gingival Recession, Composite Resins
- Trial name
- NCT03215615
- Testing
- Periodontal surgery, Total Etch adhesive, Universal Adhesive
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Gingival Recession
Treatment Off Gingival Recession Defects Using a Xenogenic Acellular Dermal Matrix Compared to Connective Tissue Graft.
Limitation of donor site and significant postoperative morbidity are often described in connective tissue graft harvesting. We want to show if mucoderm used in tunnel technique to recover miller class I and II recessions defects…
- Trial name
- MUCODERM (NCT03162016)
- Testing
- transplants
- Where
- France
- Volunteers
- 12 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Gingival Recession, Generalized
Comparison Between Connective Graft and Xenogeneic Matrix, in Patients With Multiple Gingival Recessions
Subepithelial connective tissue graft (SCTG) is considered the gold standard for root coverage treatment. However, it is associated with postoperative morbidity, limited amount of donor tissue, and longer surgical time.
- Trial name
- NCT03207984
- Testing
- Root coverage surgery
- Where
- Brazil
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Periodontal Diseases
Pinhole Surgical Technique Compared to Connective Tissue Graft in Treatment of Gingival Recession
This study compares the efficacy of root coverage achieved by the Pinhole Surgical Technique (PST) technique and the Connective Tissue Graft (CTG) technique in the treatment of Miller class I and II gingival recession defects.
- Trial name
- NCT04356391
- Testing
- Connective Tissue Graft Technique, Pinhole Surgical Technique
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- State University of New York at Buffalo
Gingival Recession, Lack of Keratinized Gingiva (Disorder)
Progenitor Potential of Mesenchymal Stem Cells in Palatal Tissue Harvested From Molar and Premolar Sites
The primary purpose of this protocol is to isolate, investigate and compare the regenerative and differentiation potential of mesenchymal stem cells (MSC's) in the gingival (gum) tissue harvested from two different locations from…
- Trial name
- NCT03570333
- Testing
- progenitor potential of Gingival Mesenchymal cells
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Gingival Recession, Localized
The Efficacy of Amnion Chorion Allograft in Management of Gingival Recession.
the main goal of this clinical trial is to test the efficacy of amnion Chorion allograft in managing gingival recession. The main questions it aims to answer are: Is it effective in treating gingival recession, and how it…
- Trial name
- NCT06508476
- Testing
- Amnion Chorion membrane, connective tissue graft
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- Minia University
Gingival Recession
Advanced Platelet-Rich Fibrin and Coronally Advanced Flap for Gingival Recession Treatment
The goal of this clinical trial is to learn if adding a natural healing material works better to treat receding gums in adults. Receding gums is a condition where the gum tissue pulls back and exposes the tooth root.
- Trial name
- NCT07624591
- Testing
- Coronally Advanced Flap (CAF) combined with Advanced Platelet-Rich Fibrin (A-PRF), Coronally Advanced Flap (CAF) alone
- Where
- Vietnam
- Volunteers
- 11 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Gingival Recession
Gingival Augmentation and Root Coverage With Superficial and Deep Cut Acellular Dermal Matrices
This entire protocol involves procedures that are standard care and will randomize subjects to of one two routine care procedures. Patients needing root coverage for gingival recession will be enrolled.
- Trial name
- NCT05956496
- Testing
- Allograft Material ADM-S, Allograft Material ADM-D
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Gingival Recession, Localized
Comparing Two Different Tunneling Technique for Gingival Recession Treatment Using Two Different Matertial
The goal of this clinical trial is to compare two different tunneling surgical technique in treatment of gingival recession using two different materials.
- Trial name
- NCT06065774
- Testing
- The Laterally Closed Tunnel Technique with SCTG, The Laterally Closed Tunnel Technique with collagen matrix mucograft, Modified Coronally Advanced Tunnel Technique with SCTG.
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Gingival Recession
Diode Laser for Harvesting Gingival Graft
Aims: The aim of present randomized controlled clinical study was to evaluate whether the additional use of diode laser would facilitate the donor surgery, improve the palatal wound healing and reduce post-operative morbidity…
- Trial name
- NCT02441127
- Testing
- diode laser group, scalpel control group
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Cukurova University
Gingival Recession, Generalized, Gingival Recession, Localized
Clinical and Histological Evaluation of Subepithelial Connective Tissue Graft Maturation at Different Healing Timepoints, With and Without Topical Application of a Polynucleotide- and Hyaluronic Acid-Based Gel
This study evaluates whether a 9-week healing interval is sufficient for subepithelial connective tissue graft (SCTG) maturation after palatal harvesting, and whether topical application of a polynucleotide and hyaluronic acid…
- Conditions
- Gingival Recession, Generalized, Gingival Recession, Localized, Wound Healing, Palate; Wound
- Trial name
- NCT07708051
- Testing
- polynucleotide and hyaluronic acid gel, subepithelial connective tissue graft harvesting
- Volunteers
- 15 people
- Sponsor
- University of Sao Paulo