Clinical trials: Reconstructive Surgical Procedure
Pelvic Organ Prolapse
Vaginal Orthosis Use After Vaginal Reconstructive Surgery
A novel vaginal orthosis, or splint, made of silicone will be used daily to help support the healing vaginal reconstruction during the post-operative phase from week 2 to week 12.
- Trial name
- NOVa (NCT05812859)
- Testing
- Vaginal Orthosis (COSM Medical)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Anterior Cruciate Ligament Injury
Acute Anterior Cruciate Ligament Rupture; RecOnsTruction Or Repair?
To investigate the hypothesis that suture repair of a ruptured vkb, combined with a dynamic intraligamentary stabilization and microfracture of the femoral notch, results in at least equal effectiveness compared with an ACL…
- Trial name
- ROTOR (NCT02310854)
- Testing
- ACL Repair, ACL reconstruction
- Where
- Netherlands
- Volunteers
- 48 people
- Sponsor
- Orthopedisch Centrum Oost Nederland
Abdominal Pain, Acute Pain
Diagnostic Performance of Low-Dose CT for Acute Abdominal Conditions
The goal of this non-inferiority observational study is to assess the diagnostic performance of low-dose CT with deep learning image reconstruction (DLIR) in adult participants with acute abdominal conditions.
- Conditions
- Abdominal Pain, Acute Pain, Acute Cholecystitis, Acute Appendicitis
- Trial name
- DETECT_Acute (NCT05651360)
- Testing
- low-dose CT
- Where
- 2 sites in Denmark, Norway
- Volunteers
- 246 people
- Sponsor
- Oslo University Hospital
Breast Cancer
Mastectomy Reconstruction Outcomes Consortium (MROC) Study
The MROC Study seeks to evaluate and compare from the patient's point of view the leading options for breast reconstruction after mastectomy.
- Trial name
- MROC (NCT01723423)
- Where
- 11 sites in United States, Canada
- Volunteers
- 4,436 people
- Sponsor
- University of Michigan
Plastic Surgery, Reconstructive Surgery
STARS-R Registry: Retrospective Analysis of Poly-4-hydroxybutyrate (P4HB) Scaffold Use
This is a retrospective chart review performed at multiple clinics aimed at providing real-world evidence of the use and safety of the P4HB scaffold.
- Trial name
- NCT04195854
- Testing
- P4HB product
- Where
- 10 sites in United States
- Volunteers
- 1,183 people
- Sponsor
- C. R. Bard
Anterior Cruciate Ligament (ACL) Tear, Anterior Cruciate Ligament Reconstruction Rehabilitation
Analysis Of Knee Joint Of Patients With Anterior Cruciate Ligament Injury Undergoing Physiotherapy After Two Different Surgical Techniques: A Randomized Clinical Trial.
The objetive is compare knee joint stability, functional capacity, postural control, activation, and muscle strength of patients undergoing conventional Anterior Cruciate Ligament Reconstruction or the conventional Anterior…
- Trial name
- NCT06809920
- Testing
- Group 1 ACL reconstruction with quadruple flexor tendons and conventional physiotherapy, Group 2 ACL reconstruction with quadruple flexor tendons + ALL reconstruction
- Where
- 2 sites in Brazil
- Volunteers
- 26 people
- Sponsor
- Universidade Estadual de Londrina
The Impact of Adipose Tissue Quality on Fat Graft Retention
Lipofilling: Optimal Harvesting Techniques for Breast Reconstruction After Mastectomy in Plastic Aesthetic and Reconstructive Surgery
The primary aim of this project is to standardize the method for lipofilling by identifying the best technique. In this context, the study will investigate the impact of adipose tissue composition and ideal quantity of the…
- Trial name
- LipoTech (NCT05286424)
- Testing
- fat grafting
- Where
- Austria
- Volunteers
- 10 people
- Sponsor
- Medical University of Graz
Surgical Site Infection
SSI Rates in Patients Undergoing Mastectomy Without Reconstruction- A Multicenter, Double-blinded RCT.
Breast cancer is the second most prevalent malignancy in the world and an important component of treatment warrants surgical procedures such as mastectomy.
- Trial name
- NCT04577846
- Testing
- Cephalexin 500 MG
- Where
- 3 sites in Pakistan
- Volunteers
- 384 people
- Sponsor
- Aga Khan University
Anterior Cruciate Ligament Reconstruction
Effect of Patient Resilience on Return to Sport Post ACL Reconstruction Surgery
Despite the large majority of patients that undergo ACL reconstruction reporting successful outcomes in regard to tests of knee function, only about 2/3 return to their prior level or athletic activity after surgery.
- Trial name
- NCT03013231
- Testing
- Brief Resilience Scale
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- St. Louis University
Periacetabular Tumor
A Randomized Controlled Study Evaluating Modified Cup Anteversion Placement in Prevention of Postoperative Dislocation in Patients Undergoing Acetabular Tumor Resection and Reconstruction
The purpose of this clinical study is to investigate whether patients who receive modified anteversion angle (( α-15°)±10°) of the acetabular cup have a lower risk of dislocation within one year after surgery, compared to…
- Trial name
- NCT05593146
- Testing
- modified anteversion angle placement(( α-15°)±10°), conventional anteversion angle placement ( α±10°)
- Where
- China
- Volunteers
- 118 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Breast Cancer Lymphedema
Does Immediate Lymphatic Reconstruction Decrease the Risk of Lymphedema After Axillary Lymph Node Dissection
The researchers are doing this study to see if having immediate lymphatic reconstruction after axillary lymph node dissection (ALND) can decrease the development of lymphedema, a side effect of ALND.
- Trial name
- NCT04241341
- Testing
- Axillary Lymph Node Dissection with Immediate Lymphatic Reconstruction, Axillary Lymph Node Dissection without Immediate Lymphatic Reconstruction, quality-of-life questionnaires
- Where
- 7 sites in United States
- Volunteers
- 180 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
ACL Reconstruction
Methylprednisolone Addition to Multimodal Pain Regimens After Anterior Cruciate Ligament Reconstruction
Patients who are being seen for ACL tears will be approached in the UAB Orthopedic Clinic. Included patients will be those aged 14-65 undergoing ACL Reconstruction.
- Trial name
- NCT07605923
- Testing
- Methyl Prednisolone (MP), Standard Post-Operative Pain Control, Surgeon's Standard ACL Postoperative Regimen
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- University of Alabama at Birmingham
Venous Thrombosis
Ongoing Registry of Deep Venous Reconstructions
Ongoing registration of deep venous obstructive disease patients treated by means of percutaneous transluminal angioplasty (PTA) and stenting with or without endophlebectomy (surgical desobstruction, also termed endovenectomy) of…
- Trial name
- NCT02650453
- Testing
- Deep venous reconstruction
- Where
- Netherlands
- Volunteers
- 1,000 people
- Sponsor
- Maastricht University Medical Center
Otorhinolaryngologic Diseases
Reconstruction Implant Bone After Removal Using Porous Titanium Prosthesis
This trial will study the reconstruction of the anterior part of the mandible and the adjacent soft tissue parts by a mandibular prosthesis made in porous titanium, associated or not, to a latissimus dorsi or pectoral flap, to…
- Trial name
- NCT00213837
- Testing
- Mandibular prosthesis made of a new highly biointegratable material
- Where
- France
- Volunteers
- 7 people
- Sponsor
- University Hospital, Strasbourg, France
Congenital Heart Disease
Study to Assess Safety of the Pulmonary Valved Conduit (PV-001) in Subjects Undergoing Right Ventricular Outflow Tract Reconstruction
The study is a prospective, non-randomised, open label clinical study to assess the safety of the Bioabsorbable Pulmonary Valved (PV) conduit (PV-001) in subjects > 2 years and < 22 years of age, undergoing Right Ventricular…
- Trial name
- NCT02700100
- Testing
- Bioabsorbable Pulmonary Valved Conduit (PV-001)
- Where
- 3 sites in Hungary, Malaysia and 1 more
- Volunteers
- 12 people
- Sponsor
- Xeltis
Wound Healing, Surgical Wound
Evaluating rhPDGF-BB-Enhanced Wound Matrix for Head and Neck Reconstruction
Skin cancers such as basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and melanoma lesions that develop on the head and neck are treated by Mohs surgery or wide local excision to remove all tumor cells and preserve the…
- Trial name
- NCT06634030
- Testing
- RhPDGF-BB, Saline
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Vanderbilt University Medical Center
Reconstructive Tissue Surgery
Glucose Monitoring in Tissue Transfers
The purpose of this study is to determine if 1) a continuous glucose monitoring system can measure glucose levels in transferred tissue during reconstructive surgery, and 2) if glucose measurements from a continuous glucose…
- Trial name
- NCT00962130
- Testing
- Continuous glucose monitoring system
- Where
- United States
- Sponsor
- University of Wisconsin, Madison
Thoracic
Surgical Outcome Studies in Thoracic Wall Reconstruction With Codubix® Ribs
The aim of this observational study is to analyze the short- and long-term outcome after surgical implantation of the Codubix® Ribs prosthesis in a descriptive and non-statistical way.
- Trial name
- NCT06448728
- Where
- Switzerland
- Volunteers
- 9 people
- Sponsor
- University Hospital, Basel, Switzerland
Breastcancer, Mastectomy
Study Evaluating the Efficacy of Loco-regional Anaesthesia PECS on Chronic Pain of a Mastectomy
A non-randomized, mono-centric, prospective interventional study that will assess the efficacy of the loco-regional anesthesia PECS on the rate of chronic pain, 6 month after a patient will have either received a mastectomy or a…
- Trial name
- PECS (NCT03023007)
- Testing
- Loco-regional anaesthesia
- Where
- France
- Volunteers
- 194 people
- Sponsor
- Centre Oscar Lambret
Anterior Cruciate Ligament Tear
Comparison of Early Versus Delay Reconstruction in Anterior Cruciate Ligament Tearing
The purpose of this study is to determine which surgical method is better for anterior cruciate ligament teas in outcomes.
- Trial name
- NCT01580722
- Testing
- early reconstruction, delay reconstruction
- Where
- Iran
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences