Clinical trials: Reconstructive Surgical Procedures
Breast Cancer, LCIS
Tumor: Breast Ratio Study
This is an observational study of 3 arms: breast conservation therapy, mastectomy and reconstruction, and mastectomy only.
- Conditions
- Breast Cancer, LCIS, DCIS
- Trial name
- T:B (NCT02216136)
- Where
- United States
- Volunteers
- 162 people
- Sponsor
- Washington University School of Medicine
Breast Implant; Complications, Breast Implant Protrusion
Standard Silicone-based vs. B-Lite® Light Weight Breast Implant After Total Mastectomy and Radiotherapy for Breast Cancer
Reconstructive surgery with breast implants after total mastectomy for breast cancer is invariably related to several possible complications, such as atrophy of surrounding tissues, skin thinning, capsular contracture, wound…
- Conditions
- Breast Implant; Complications, Breast Implant Protrusion, Breast Cancer, Radiotherapy Side Effect
- Trial name
- BLITE-01 (NCT03737500)
- Testing
- B-Lite® light weight breast implant, Standard silicone-based breast implant
- Where
- Italy
- Volunteers
- 49 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Mastectomy; Lymphedema, Breast Cancer
Polyurethan Versus Non-polyurethan Covered Implants in Combination With Radiotherapy
The purpose of this multicenter retrospective cohort study is to determine the effect of radiotherapy on capsular contraction and implant loss rates in patients undergoing prepectoral immediate implant-based breast reconstruction…
- Trial name
- PRExRT (NCT06747065)
- Testing
- Radiotherapy
- Where
- Switzerland
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Basel, Switzerland
Papilla Reconstruction
Comparison of Connective Tissue Graft Versus Titanium Papillary Inserts in the Surgical Reconstruction of Interdental Papilla.
Aim and Objectives: The study aimed to evaluate the effectiveness of titanium inserts for interdental papilla reconstruction, comparing it with the Han and Takei technique using subepithelial connective tissue grafts.
- Trial name
- NCT07401667
- Testing
- TITANIUM INSERTS, CONNECTIVE TISSUE GRAFT
- Where
- India
- Volunteers
- 18 people
- Sponsor
- Dr R Viswa Chandra
Complete Tear, Knee, Anterior Cruciate Ligament
Early Viscosupplementation After ACL Reconstruction: a Randomized Controlled Trial
The possibility of using an intra-articular agent such as hyaluronic acid (HA) to reduce the post-operative inflammatory stress on the knee joint, limiting the use of other pain-killers and promoting a faster recovery after ACL…
- Trial name
- HA-ACL (NCT02630407)
- Testing
- viscosupplementation
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Istituto Ortopedico Rizzoli
Cleft Lip, Cleft Lip and Palate
Assessing the Results of Lip Surgery in Patients With Cleft Lip and Palate
The purpose of this study is to determine whether secondary (revision) surgery to the lip in patients with cleft lip and palate is effective in improving lip function and appearance.
- Trial name
- NCT00070811
- Testing
- Lip revision surgery
- Where
- United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Non-Small Cell Lung Cancer (NSCLC)
FDG PET/CT in Lung Cancer Staging
Prospective study of the effects of image acquisition and reconstruction parameters on accuracy of FDG PET/CT mediastinal nodal staging in NSCLC
- Trial name
- NCT02738398
- Testing
- FDG PET/CT
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Anterior Cruciate Ligament Reconstruction Rehabilitation
Effects of Core Exercises on Balance in People With and Without ACL Surgery
The main purpose of this study is to evaluate and compare the effects of an 8-week core stabilization exercise program on balance, trunk muscle endurance, and lower body strength.
- Trial name
- NCT07328139
- Testing
- Core Stabilization Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Biruni University
Anterior Cruciate Ligament Reconstruction
Iovera° to Treat Pain Associated With ACL Reconstruction and Rehabilitation
To evaluate the outcomes of patients undergoing iovera° treatment of the ISN and AFCN on postoperative knee pain and function following anterior cruciate ligament reconstruction
- Trial name
- NCT03688477
- Testing
- iovera°
- Where
- United States
- Sponsor
- Pacira Pharmaceuticals, Inc
Breast Reconstruction, Abdominal Wall Morbidity
Changes To The Abdominal Wall After DIEP Flap Breast Reconstruction
The purpose of this study was to perform an evaluation of the structural changes in the abdominal wall after harvesting a DIEP flap in breast reconstruction.
- Trial name
- NCT02563977
- Testing
- 2 year postop CT scan of the abdomen
- Where
- Norway
- Volunteers
- 14 people
- Sponsor
- Oslo University Hospital
Breast Implant; Complications, Breast Implantation; Methods, Safety and Performance
Safety and Performance of Motiva® Sizers
The Motiva® Sizer clinical study is a four-year, multicenter, post-marketing, and cohort study, designed to confirm the safety and performance of Motiva® Sizer in breast augmentation or reconstruction procedures.
- Conditions
- Breast Implant; Complications, Breast Implantation; Methods, Safety and Performance, Mammaplasty, Breast Reconstruction
- Trial name
- NCT06274736
- Testing
- Motiva Sizer
- Where
- Costa Rica
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Establishment Labs
ACL Reconstruction
Application of Multiple Vertical Jump Tests in Return-to-Play Assessment for Anterior Cruciate Ligament Reconstruction Athletes
Anterior cruciate ligament (ACL) injury is a common sports-related injury, particularly in sports that require extensive jumping and cutting movements.
- Trial name
- RTP-VJ (NCT07297511)
- Where
- Taiwan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University
the Clinical Effect of Surgical Tube Technique in Reconstruction of the Interproximal Papilla
Clinical Evaluation of the Use of Surgical Tube Technique Versus Hyaluronic AcidInjection in Reconstruction of the Interproximal Papilla
Restoring defective interdental papilla partially or totally in structure and function creates a challenge in dental field owing to the small working space and limited blood supply to the area.
- Trial name
- NCT05235477
- Testing
- Tube technique
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- waleed mohammad sabry
Scar Conditions and Fibrosis of Skin
Dermabrasion for Free Flap Aesthetic Enhancement
The purpose of this study is to evaluate the aesthetic benefit and safety of serial dermabrasion for free flap skin paddles and donor site scars in head and neck reconstruction.
- Trial name
- NCT07233200
- Testing
- Dermabrasion
- Volunteers
- 40 people
- Sponsor
- Milton S. Hershey Medical Center
Breast Cancer
SurgiMend in Two-stage Implant-based Breast Reconstruction in Patients With Pre-Mastectomy Radiotherapy
This is a prospective clinical study comparing two-stage breast reconstruction following mastectomy with and without the use of SurgiMend® PRS fetal bovine collagen matrix in patients with pre-mastectomy radiation therapy.
- Trial name
- NCT01959867
- Testing
- SurgiMend® PRS, No Intervention
- Sponsor
- Integra LifeSciences Corporation
Postoperative Pain Management
Perioperative Administration of Pregabalin in Patients Undergoing Arthroscopic Anterior Cruciate Ligament Reconstruction
To prove pregabalin's efficacy and safety in Thai patients scheduled for arthroscopic ACL reconstruction
- Trial name
- NCT01242332
- Testing
- Pregabalin
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Prince of Songkla University
Fistula, Surgery Site Fistula
ERAS in Gastrointerstinal Fistulas.
An enterocutaneous fistula (ECF) poses a major surgical problem. The definitive surgical repair of persistent fistulas remains a surgical challenge with a high rate of re-fistulation and mortality, and the reasons for that is not…
- Trial name
- NCT04771832
- Testing
- ERAS
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Stanley Dudrick's Memorial Hospital
Ventral Hernia
Hernia Repair in Multiply Morbid Patients
Support of a ventral hernia repair with a prosthetic mesh has been demonstrated to result in a diminished rate of hernia recurrence.
- Trial name
- RAM2P (NCT00930787)
- Testing
- Strattice Reconstructive Tissue Matrix (Hernia Repair), Proceed Surgical Mesh (Hernia repair)
- Where
- 13 sites in United States
- Volunteers
- 23 people
- Sponsor
- LifeCell
Breast Cancer, Cancer
Quantification of Breast Sensation Following Postmastectomy Breast Reconstruction
The purpose of this study is to evaluate the return of sensation in the breast(s) following breast mastectomy with and without reconstruction.
- Trial name
- NCT00588419
- Testing
- breast exam and questionaire
- Where
- United States
- Volunteers
- 153 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
ACL - Anterior Cruciate Ligament Rupture
Soft-tissue Quadriceps Autograft ACL-reconstruction in the Skeletally-immature vs. Hamstrings
To date, the use of the quadriceps tendon as an autograft option in primary paediatric Anterior Cruciate Ligament (ACL) reconstruction has not been well studied.
- Trial name
- SQuASH (NCT03896464)
- Testing
- Soft tissue hamstring autograft, Quadriceps tendon autograft
- Where
- 6 sites in Canada, Japan
- Volunteers
- 352 people
- Sponsor
- McMaster University