Clinical trials: Recovery From Anesthesia
Postoperative Residual Curarisation, Postoperative Hypoxemia
Postoperative Residual Curarisation at Arrival in the Post-anesthesia Care Unit
Several studies have documented that neuromuscular block often persists in the postanesthesia care unit (PACU). Residual paralysis is associated with postoperative complications such as hypoxia, weakness, and respiratory failure.
- Conditions
- Postoperative Residual Curarisation, Postoperative Hypoxemia, Postoperative Airway Obstruction
- Trial name
- NCT01362647
- Testing
- neuromuscular transmission monitoring, Pulse oximetry measurement
- Where
- Belgium
- Volunteers
- 625 people
- Sponsor
- Onze Lieve Vrouw Hospital
Delayed Emergence From Anesthesia
Effect of Calling the Patient's Name on Recovery From General Anesthesia
The purpose of this study is to find if we can shorten the recovery time by calling the patient's name during anesthesia reversal.
- Trial name
- NCT02149745
- Testing
- Calling the patient's name, Not calling the patient's name
- Where
- South Korea
- Volunteers
- 101 people
- Sponsor
- Seoul National University Hospital
Anesthesia, Surgery
Hypercapnic Spontaneous Hyperpnoea and Recovery From Sevoflurane Anesthesia
The rate of elimination of inhalation agent is directly proportional to the degree of alveolar ventilation. Using Isocapnic Hyperpnoea (IH) device, it is possible to maintain constant end-tidal CO2 with increased minute…
- Trial name
- NCT01151267
- Testing
- Standard Anesthesia management for post surgical patients, Hypercarbic Spontaneous Hyperpnoea
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- University Health Network, Toronto
Respiratory Function, Pediatric Anesthesia
Effects of Different Inspiratory:Expiratory Ratios on Respiratory and Recovery Outcomes During Dental Procedures Under General Anesthesia in Pediatric Patients
This observational study aims to evaluate the effects of different inspiratory to expiratory (I:E) ratios (1:2 vs. 1:3) during mechanical ventilation in pediatric patients undergoing dental procedures under general anesthesia.
- Conditions
- Respiratory Function, Pediatric Anesthesia, General Anesthesia
- Trial name
- NCT07323420
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Residual Neuromuscular Block
Impact of Sugammadex Versus Neostigmine on Early Postoperative Pulmonary Function
Residual neuromuscular blockade (NMB) after general anesthesia increases the risk of postoperative respiratory complications (atelectasis, pneumonia, re-intubation) and delays pulmonary function recovery.
- Trial name
- NCT07309393
- Testing
- Sugammadex, Neostigmine
- Where
- 3 sites in China
- Volunteers
- 240 people
- Sponsor
- Shanghai Pulmonary Hospital, Shanghai, China
Intensive Care, Surgical, Postoperative Care
Emergence Agitation in Adult Patients After Intracranial Surgery
Emergence agitation is a frequent complication that can have serious consequences during recovery from general anesthesia. However, agitation has been poorly investigated in patients after craniotomy.
- Conditions
- Intensive Care, Surgical, Postoperative Care, Neurosurgery
- Trial name
- NCT02318199
- Testing
- Anesthesia recovery after intracranial surgery
- Where
- 4 sites in China
- Volunteers
- 400 people
- Sponsor
- Capital Medical University
Pediatric
Effects of Chloral Hydrate on Induction, Maintenance, and Recovery From Sevoflurane Anesthesia in Day-case Pediatric Surgery
Effects of Choral Hydrate on Induction, Maintenance, and Recovery from Sevoflurane Anesthesia in Day-case Pediatric Surgery
- Trial name
- NCT01149226
- Testing
- chloral hydrate
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Yonsei University
Ventilatory Depression, Postoperative Respiratory Failure
Hyperoxia on Ventilation During Recovery From General Anesthesia
In this preliminary, crossover investigation the investigators will examine the effect of oxygen supplementation on the recovery of breathing in the immediate post-anesthesia period.
- Trial name
- NCT05922020
- Testing
- Oxygen gas
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Stanford University
Motility Function
Esophageal Manometry During Recovery From Anesthesia: Pilot Study
1. An intact pharyngoesophageal reflex is essential to protect the upper airway from aspiration of either mouth contents or regurgitated gastric refluxate. This reflex is essential at protecting the airway in all patients. 2.
- Trial name
- EMAP (NCT02661386)
- Testing
- Motility Procedure
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of California, San Francisco
Anesthesia
EEG Studies of Sevoflurane-Induced General Anesthesia
The investigators are performing this research study to find out how and where the anesthetic drugs sevoflurane and ketamine act in the brain.
- Trial name
- NCT03503578
- Testing
- Sevoflurane, Ketamine
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Laryngectomy; Status
Effect of Dexmedetomidine in Preventing Cough and Postoperative Pain After Laryngeal Surgery for Cancer
Background: During emergence from anesthesia for partial and total laryngectomy, severe airway reflex and systemic hypertension during recovery may lead to pneumoderm, hemorrhage, pneumomediastinum or pneumothorax.
- Trial name
- NCT03918889
- Testing
- Dexmedetomidine Injectable Product, Midazolam injection
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Anesthesia Recovery, Anesthesia Emergence
Intravenous Dexmedetomidine For The Quaity Of Emergence From General Anesthesia
In a prospective randomized clinical trial involving adult patients undergoing elective surgery under general anesthesia, the investigators will enroll 216 patients, and evaluate 3 doses of prophylactic dexmedetomidine as a means…
- Conditions
- Anesthesia Recovery, Anesthesia Emergence, Shivering, Postoperative Recovery
- Trial name
- NCT02141412
- Testing
- dexmedetomidine 0.25 µg/kg IV, dexmedetomidine 0.5 µg/kg IV, dexmedetomidine 1 µg/kg IV
- Where
- Lebanon
- Volunteers
- 216 people
- Sponsor
- American University of Beirut Medical Center
Residual Neuromuscular Blockade
Electromyographic Assessment of Onset and Recovery of Neuromuscular Blockade
Residual neuromuscular blockade (weakness) is a common occurrence in the postanesthesia care unit when muscle relaxant drugs have been used in the operating room.
- Trial name
- NCT01678625
- Testing
- Train-of-four ratio calculation (T4-EMG)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Endeavor Health
Quality of Recovery (QoR-15), Quality of Recovery From Anaesthesia
Validation of the Setswana Translated Quality of Recovery Questionnaire in Orthopaedic Patients at a Tertiary Hospital in South Africa
This observational study aims to evaluate the validity, reliability and feasibility of the Setswana-translated version of the 15-item Quality of Recovery (QoR-15) questionnaire.
- Trial name
- NCT07194369
- Where
- South Africa
- Volunteers
- 150 people
- Sponsor
- Sefako Makgatho Health Sciences University
Pain, Postoperative
Biobehavioral Recovery From Surgery and Anesthesia
Reducing postoperative pain leads to increased patient comfort and facilitates speedy recovery and discharge from the hospital following surgery.
- Trial name
- NCT00176696
- Testing
- Use of FACE monitor and BIS monitor
- Volunteers
- 20 people
- Sponsor
- University of Medicine and Dentistry of New Jersey
Residual Neuromuscular Blockade
Predictor of Residual Neuromuscular Blockade in Recovery Room After General Anesthesia
Background When general anesthesia was performed, neuromuscular blocking agents (NMBAs) are frequently used for facilitate tracheal intubation and keep patient still and relax during surgery.
- Trial name
- NCT02146859
- Where
- Thailand
- Volunteers
- 222 people
- Sponsor
- Mahidol University
Mechanical Ventilation
Thoraco-abdominal Volume Variations During Anesthesia Studied by OEP.
The aim of this study is to examine chest wall volume changes monitored by opto-electronic plethysmography during recovery from anesthesia and early postoperative period.
- Trial name
- NCT01474850
- Testing
- lung recruitment maneuver
- Where
- Sweden
- Volunteers
- 18 people
- Sponsor
- Uppsala University Hospital
Residual Neuromuscular Blockade
Comparison of the ToFscan and TetraGraph During Recovery of Neuromuscular Function in the Post Anesthesia Care Unit
The aim of this investigation is to compare the performance of two quantitative monitors utilized on post-anesthesia recovering patients.
- Trial name
- NCT03920670
- Testing
- TetraGraph (TG), ToFscan (TS)
- Where
- 3 sites in United States, Hungary
- Volunteers
- 120 people
- Sponsor
- Mayo Clinic
General Anesthetic, Electroencephalographic
Non-pharmacological Auditory and Somatosensory Stimulation in Anesthetic Emergence
This study intends to employ verbal stimulation, tactile stimulation, and kinetic stimulation as interventions during the emergence phase from general anesthesia to facilitate recovery.
- Trial name
- NCT07339618
- Testing
- Verbal Stimulation, Shoulder Tapping, Shoulder Shaking
- Where
- China
- Volunteers
- 205 people
- Sponsor
- West China Hospital
Brain Neoplasms, Surgery
Small-dose Dexmedetomidine Effects on Recovery Profiles of Supratentorial Tumors Patients From General Anesthesia
An excellent recovery profile is critical for neurosurgical anesthesia. Rapid awakening, smooth blood pressure and heart rate (HR), a higher degree of coordination, painless or mild pain, as well as better tolerance to…
- Trial name
- NCT02007798
- Testing
- dexmedetomidine, normal saline
- Where
- China
- Volunteers
- 150 people
- Sponsor
- China Medical University, China