Clinical trials: Recovery From Anesthesia
Anesthesia
EEG Studies of Ketamine General Anesthesia
We are doing this research study to find out how and where ketamine acts in the brain. Ketamine is an anesthetic (a drug or agent used to decrease or eliminate the feeling of pain by putting you in an unconscious state).
- Trial name
- NCT03553758
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Surgery
Study of Recovery of Strength After Surgery Comparing Two Different Medications for Reversal of Muscle Relaxant
The purpose of this study is to compare two different medications (neostigmine/glycopyrrolate and sugammadex) to see if one drug improves patient comfort regarding the return of muscle strength after surgery.
- Trial name
- NCT03116997
- Testing
- Neostigmine+glycopyrrolate, Sugammadex
- Where
- 4 sites in United States
- Volunteers
- 201 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Recovery
Comparison of Recovery From General Anesthesia in Remimazolam With Flumazenil vs. Propofol
This prospective randomized trial aims to compare recovery time from discontinuation of remimazolam followed by flumazenil administration vs.
- Trial name
- NCT05435911
- Testing
- REMIMAZOLAM BESYLATE 2.5 Mg in 1 mL INTRAVENOUS INJECTION, POWDER, LYOPHILIZED, for SOLUTION [BYFAVO], Flumazenil, Propofol
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Seoul National University Hospital
Emergence Agitation, Rhinoplasty
Use of Subanesthetic Dose Propofol Before Extubation
This study investigates whether administering a low, sub-anesthetic dose of propofol before extubation can reduce emergence agitation and improve perioperative comfort in patients undergoing rhinoplasty.
- Conditions
- Emergence Agitation, Rhinoplasty, Patient Satisfaction
- Trial name
- NCT07276633
- Testing
- Propofol (Sub-Anesthetic Dose)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Yuzuncu Yil University
Anesthesiology Management
Recovery From Anesthesia After Robotic Assisted Radical Cystectomy
Robot-assisted radical cystectomy (RARC) requires specific surgical conditions: steep Trendelenburg position, prolonged pneumoperitoneum, effective neuromuscular block until the final stages of surgery.
- Trial name
- NCT03144453
- Testing
- Sugammadex Injectable Product, Neostigmine, Atropine
- Where
- 2 sites in Italy
- Volunteers
- 50 people
- Sponsor
- Regina Elena Cancer Institute
Intraoral Tumor
Differences in Speed of Recovery From Anesthesia for Intraoral Surgery
The goal of this clinical trial is to compare two groups of patients going in general anesthesia for intraoral surgery, the first group TIVA with propofol and the second group inhalational with sevoflurane.
- Trial name
- PSIOS (NCT06275087)
- Testing
- Propofol, Sevoflurane
- Where
- Croatia
- Volunteers
- 42 people
- Sponsor
- Clinical Hospital Centre Zagreb
Brain Activity Under Sedation
EEG Studies of Induction and Recovery From Propofol Induced General Anesthesia
The purpose of this study is to investigate how the commonly used anesthetic drug propofol works in the brain to produce loss of consciousness.
- Trial name
- NCT01543633
- Testing
- Propofol
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Effect of General Anesthetic Dose on Recovery From Surgery
The BALANCED Anaesthesia Study
General anaesthesia is a reversible drug-induced coma. Too little can result in patients being partially conscious during surgery; too much can slow recovery after surgery.
- Trial name
- NCT02073357
- Testing
- Light general anaesthesia (BIS = 50), deep general anaesthesia (BIS = 35)
- Where
- United States
- Sponsor
- The Cleveland Clinic
Desflurane Anesthesia, Postoperative Recovery
The Quality of Recovery From General Anesthesia With Desflurane for Fundus Surgery
The goal of this clinical trials to study and compare the effects of "desflurane with remifentanil anesthesia (study group)" and "sevoflurane with remifentanil anesthesia (control group)" for elective fundus surgery anesthesia.
- Trial name
- NCT06241131
- Testing
- Desflurane Inhalant Product
- Volunteers
- 220 people
- Sponsor
- Sichuan Provincial People's Hospital
Obstetric Anesthesia Problems, Anesthesia Morbidity
Quality of Recovery From Obstetric Anaesthesia - a Multicentre Study
Quality of recovery is an important outcome measure in anaesthesia, whilst there are validated tools for this in surgery and regional anesthesia there are no fully validated tools for obstetrics anaesthesia.
- Conditions
- Obstetric Anesthesia Problems, Anesthesia Morbidity, Quality of Life
- Trial name
- ObsQoR (NCT04192045)
- Testing
- Survey
- Where
- United Kingdom
- Volunteers
- 1,638 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Residual Neuromuscular Blockade
Thumb vs Great Toe Recovery
Researches are comparing the accuracy of measuring muscle relaxation in the thumb versus the great toe.
- Trial name
- NCT04312256
- Testing
- TetraGraph
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Mayo Clinic
Patients Recovering From Inpatient Surgery
Halo Index and Adaptive Alarm Thresholds During Routine PACU Inpatient Care: "Normal" vs. "Non-normal" Recovery
The purpose of this study is to determine whether the Halo Index has utility in detecting the difference between normal and non-normal recovery of patients in the first few hours immediately following major inpatient surgery.
- Trial name
- Halo (NCT01811433)
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Donald Mathews
C.Delivery; Surgery (Previous), Gynecological, Inappropriate Device Stimulation of Tissue
The Effect of TEAS on the Quality of Early Recovery
During the past four decades, gynecologic laparoscopy has evolved from a limited method to an advanced operative approach that frequently serves as a substitute for laparotomy.
- Conditions
- C.Delivery; Surgery (Previous), Gynecological, Inappropriate Device Stimulation of Tissue, Delayed Emergence From Anesthesia
- Trial name
- NCT02619578
- Testing
- TEAS, Con, propofol, remifentanil, vecuronium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Guizhou Provincial People's Hospital
Postoperative Recovery, Quality of Recovery From Anaesthesia
Validation of the Greek Postoperative Quality of Recovery Score 15
The goal of this observational study is to translate a patient questionnaire about recovery after an operation into Greek and assess how accurate, reliable, acceptable, and feasible this Greek version is.
- Conditions
- Postoperative Recovery, Quality of Recovery From Anaesthesia, PROMs, Validation Study
- Trial name
- (QoR-15Gr) (NCT06699823)
- Testing
- Greek version of QoR-15
- Where
- Greece
- Volunteers
- 150 people
- Sponsor
- IASO Thessalias