Clinical trials: Recovery Period
Acute Ischemic Stroke
Eptifibatide in Endovascular Treatment of Acute Ischemic Stroke (EPOCH)
The study is a single-arm, open-label, multicenter clinical trial.The primary purpose of this trial is to evaluate the incidence of symptomatic intracranial hemorrhage in patients with acute ischemic stroke within 48 hours after…
- Trial name
- NCT03844594
- Testing
- Eptifibatide Injection
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Ministry of Science and Technology of the People´s Republic of China
Observation of Neuromuscular Block, Complication of Ventilation Therapy
Deep Neuromuscular Block During General Anaesthesia in Robotic Surgery
The aim of this project is to show, whether the use of the deep neuromuscular block in certain laparoscopic robot-assisted surgery can positively influence main physiological functions compared to the use of standard…
- Conditions
- Observation of Neuromuscular Block, Complication of Ventilation Therapy, Postoperative Recovery
- Trial name
- NCT03420937
- Testing
- Sugammadex, Neostigmine, Atropin Biotika
- Where
- Czechia
- Volunteers
- 138 people
- Sponsor
- University Hospital Olomouc
Osteoarthritis of Knee, Recovery Following Primary Total Knee Arthroplasty
Perioperative Colchicine for TKA
This study is a prospective, randomized, double-blinded, placebo-controlled study of the drug colchicine in the acute postoperative period for patients who are undergoing a total knee arthroplasty (TKA).
- Conditions
- Osteoarthritis of Knee, Recovery Following Primary Total Knee Arthroplasty, Perioperative Pain Control
- Trial name
- NCT06936709
- Testing
- Colchicine 1.8 mg + 0.6 mg
- Volunteers
- 75 people
- Sponsor
- Geisinger Clinic
Anemia
Efficiency of Patient Blood Management Protocol in Gynecological Surgery Department (PERIOPESGYNECO)
Perioperative anemia is associated with higher risk of red blood cell transfusion, higher rates of morbimortality and lower quality of postoperative recovery.
- Trial name
- PERIOPESGYNECO (NCT06493435)
- Volunteers
- 160 people
- Sponsor
- University Hospital, Angers
Anesthesia Recovery Period, Postoperative Complications
The Anesthesia Effects of Dexmedetomidine Combined With Desflurane or Propofol in Lobectomy
In one-lung ventilation surgery, compared with dexmedetomidine combined with propofol, dexmedetomidine combined with desflurane may be beneficial to accelerate patients' recovery and reduce postoperative pulmonary complications…
- Trial name
- NCT06207344
- Testing
- Dexmedetomidine and propofol, Dexmedetomidine and desflurane
- Where
- 2 sites in China
- Volunteers
- 120 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Fungal Infection
A Study to Assess the Mass Balance Recovery and Metabolite Profile & Identification of [14C]-APX001 in Healthy Males
This is a single-center, open-label, non-randomized, single dose study in healthy male subjects. It was planned to enroll 2 cohorts of 5 subjects (10 subjects in total), with the target of achieving data in 4 evaluable subjects…
- Trial name
- NCT04804059
- Testing
- [14C]-APX001 Oral Solution, [14C]-APX001 Solution for Infusion
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Basilea Pharmaceutica
Stroke, Cerebrovascular Accident
Fluoxetine Opens Window to Improve Motor Recovery After Stroke
The FLOW trial is a randomized placebo-controlled trial analyzing the effect of coupling an anti-depressant, fluoxetine (Prozac), and exercise to improve motor recovery following a stroke.
- Conditions
- Stroke, Cerebrovascular Accident, Cerebral Infarction, Brain Infarction
- Trial name
- FLOW (NCT03448159)
- Testing
- Fluoxetine Hydrochloride, Exercise Program
- Where
- 8 sites in Canada
- Volunteers
- 52 people
- Sponsor
- University Health Network, Toronto
Cranial Neurosurgery
Heart Rate Variability and Processed EEG Features as Predictors of Postoperative Outcomes After Cranial Neurosurgery
Patients undergoing cranial neurosurgery face a high-risk postoperative period, particularly during emergence from anesthesia and early recovery in the post-anesthesia care unit (PACU).
- Trial name
- HERO-PACU (NCT07443072)
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Healthy Subjects
A Study In Healthy Male Volunteers Designed To Investigate How A Radiolabelled Medicine Is Broken Down And Removed From The Body
The current study is designed to generate data for the investigation of absorption, distribution, metabolism and elimination (ADME) processes of pracinostat in humans, as well as generating samples for metabolite profiling and…
- Trial name
- NCT03495934
- Testing
- pracinostat
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Helsinn Healthcare SA
Pain, Postoperative, Analgesia
Prediction of Postoperative Pain by Nociception Monitoring
General anesthesia is a combination of hypnotic drugs and opioid analgesics. Modern general anesthesia aims to treat nociception induced by surgical stimulation while avoiding an overdose of opioid analgesics and reducing…
- Conditions
- Pain, Postoperative, Analgesia, Anesthesia Recovery Period, Opioid Use
- Trial name
- PredictPain (NCT05063227)
- Testing
- Observational: analgesia monitoring indices and changes in heart rate
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Acute Gastrointestinal Perforation, Enhanced Recovery After Surgery
Enhanced Recovery After Surgery Promotes the Rehabilitation of Patients With Acute Gastrointestinal Perforation in Perioperative Period
The enhanced recovery after surgery(ERAS) has been gradually extended from its initial colorectal surgery to almost all surgical fields. However, there are few reports about the application value of ERAS in emergency surgery.
- Trial name
- NCT07008313
- Testing
- The enhanced recovery after surgery, Traditional treatment methods.
- Where
- China
- Volunteers
- 362 people
- Sponsor
- Hebei Medical University
Patients Recovering From Inpatient Surgery
Halo Index and Adaptive Alarm Thresholds During Routine PACU Inpatient Care: "Normal" vs. "Non-normal" Recovery
The purpose of this study is to determine whether the Halo Index has utility in detecting the difference between normal and non-normal recovery of patients in the first few hours immediately following major inpatient surgery.
- Trial name
- Halo (NCT01811433)
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Donald Mathews
Is an Only Child
Use of Intraoperative Clonidine for Prevention of Postoperative Agitation in Pedriatic Anesthesia With Sevoflurane.
The purpose of this study is to determine efficacy of intraoperative clonidine to prevent postoperative agitation in pediatric anesthesia with sevoflurane.
- Trial name
- NCT02181543
- Testing
- Clonidine
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Professor Fernando Figueira Integral Medicine Institute
Anesthesia, Analgesia
Genetic Variants and Perioperative Morbidity and Mortality
Prospective association study to analyse perioperative patients' outcome. Outcome comprises intraoperative and postoperative complications e.g.
- Conditions
- Anesthesia, Analgesia, Surgical Procedure, Operative
- Trial name
- NCT02124499
- Where
- Switzerland
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Brain Injuries
Refined Nursing in Rehabilitation Training
This study is to explore the clinical effect of refined nursing in rehabilitation training for patients with brain injury during the recovery period.
- Trial name
- NCT06329934
- Testing
- Establishment of a hierarchical monitoring and management team, Assessment of pressure injury, Communication
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Xinxiang Central Hospital
Anesthesia, Spinal, Nerve Block
Machine Learning Prediction of Spinal Anaesthesia Block Duration
The duration of sensory and motor block after spinal anaesthesia varies widely between patients given the same dose of local anaesthetic.
- Conditions
- Anesthesia, Spinal, Nerve Block, Anesthesia Recovery Period
- Trial name
- NCT07816003
- Volunteers
- 255 people
- Sponsor
- Specialized Medical Center (SMC)
Pituitary Tumor
Effects of Total Intravenous Anesthesia With Propofol-remifentanil Versus Inhalational Anesthesia With Sevoflurane on Quality of Recovery in Patients Undergoing Transsphenoidal Surgery for Pituitary Tumor
A number of studies have compared the effects of total intravenous anesthesia(TIVA) versus inhalational anesthesia on perioperative period during transsphenoidal surgery.
- Trial name
- NCT02813044
- Testing
- total intravenous anesthesia (TIVA), inhalation anesthesia group
- Where
- South Korea
- Volunteers
- 82 people
- Sponsor
- Yonsei University
Healthy Volunteers
Single-dose Mass Balance Recovery and Metabolite Profile and Identification of 14C-XEN1101
This study will evaluate the mass balance recovery and metabolite profile, and will identify metabolite structures following a single oral dose of 14C-XEN1101 in healthy adult male subjects.
- Trial name
- NCT04952467
- Testing
- 14C-XEN1101
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Xenon Pharmaceuticals Inc.
Obesity, Non-diabetic Chronic Kidney Disease
SGLT2 Inhibitors in Glomerular Hyperfiltration
Glomerular hyperfiltration is a major risk factor for accelerated glomerular filtration rate (GFR) decline and renal and cardiovascular events despite optimized conservative therapy with blood pressure and blood glucose (in…
- Trial name
- EMPATHY (NCT04143581)
- Testing
- Empagliflozin 10 MG
- Sponsor
- Mario Negri Institute for Pharmacological Research
Pituitary Neoplasms
Desflurane and Anesthesia Recovery Period in Endonasal Endoscopic Pituitary Adenoma Resection
Nasal packing is required after endoscopic pituitary adenoma resection. The patient can only breathe through the mouth. The blood and secretion in the nasal cavity may be inhaled into the trachea after the operation.
- Trial name
- NCT05088252
- Testing
- Desflurane, Propofol
- Where
- China
- Volunteers
- 112 people
- Sponsor
- Beijing Tiantan Hospital